JP2023528292A5 - - Google Patents
Info
- Publication number
- JP2023528292A5 JP2023528292A5 JP2022571242A JP2022571242A JP2023528292A5 JP 2023528292 A5 JP2023528292 A5 JP 2023528292A5 JP 2022571242 A JP2022571242 A JP 2022571242A JP 2022571242 A JP2022571242 A JP 2022571242A JP 2023528292 A5 JP2023528292 A5 JP 2023528292A5
- Authority
- JP
- Japan
- Prior art keywords
- alkylene
- alkyl
- chloro
- trifluoromethyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20175820.8 | 2020-05-20 | ||
| EP20175820.8A EP3912625A1 (en) | 2020-05-20 | 2020-05-20 | Novel maxi-k potassium channel openers for the treatment of fragile x associated disorders |
| PCT/EP2021/063463 WO2021234084A1 (en) | 2020-05-20 | 2021-05-20 | Maxi-k potassium channel openers for the treatment of fragile x associated disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023528292A JP2023528292A (ja) | 2023-07-04 |
| JP2023528292A5 true JP2023528292A5 (enExample) | 2024-05-28 |
Family
ID=70802691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022571242A Pending JP2023528292A (ja) | 2020-05-20 | 2021-05-20 | 脆弱Ｘ関連障害の処置のためのｍａｘｉ－Ｋカリウムチャネルオープナー |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20240351994A1 (enExample) |
| EP (2) | EP3912625A1 (enExample) |
| JP (1) | JP2023528292A (enExample) |
| KR (1) | KR20230016194A (enExample) |
| CN (1) | CN115666554A (enExample) |
| AU (1) | AU2021274879A1 (enExample) |
| BR (1) | BR112022023318A2 (enExample) |
| CA (1) | CA3177423A1 (enExample) |
| DK (1) | DK4153170T3 (enExample) |
| ES (1) | ES3065116T3 (enExample) |
| FI (1) | FI4153170T3 (enExample) |
| HR (1) | HRP20260481T1 (enExample) |
| IL (1) | IL297493A (enExample) |
| LT (1) | LT4153170T (enExample) |
| MX (1) | MX2022014461A (enExample) |
| PH (1) | PH12022553155A1 (enExample) |
| PL (1) | PL4153170T3 (enExample) |
| PT (1) | PT4153170T (enExample) |
| RS (1) | RS67993B1 (enExample) |
| SI (1) | SI4153170T1 (enExample) |
| SM (1) | SMT202600144T1 (enExample) |
| WO (1) | WO2021234084A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023147597A2 (en) * | 2022-01-31 | 2023-08-03 | The Board Of Regents Of The University Of Texas System | Allosteric sting modulators and methods of use |
| WO2025233532A1 (en) | 2024-05-10 | 2025-11-13 | Les Laboratoires Servier | Maxi-k potassium channel openers and therapeutic applications thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565483A (en) | 1995-06-07 | 1996-10-15 | Bristol-Myers Squibb Company | 3-substituted oxindole derivatives as potassium channel modulators |
| JP2000191661A (ja) * | 1998-12-25 | 2000-07-11 | Mitsubishi-Tokyo Pharmaceuticals Inc | 環状アミド化合物 |
| FR2807038B1 (fr) | 2000-04-03 | 2002-08-16 | Sanofi Synthelabo | Nouveaux derives d'indolin-2-one, leur preparation et les compositions pharmaceutiques les contenant |
| EP1303269B1 (en) | 2000-06-29 | 2005-12-07 | NeuroSearch A/S | Use of 3-substituted oxindole derivatives as kcnq potassium channel modulators |
| US6348486B1 (en) | 2000-10-17 | 2002-02-19 | American Home Products Corporation | Methods for modulating bladder function |
| HUP0400063A2 (hu) | 2001-02-20 | 2004-04-28 | Bristol-Myers Squibb Company | Fluor-oxo-indolszármazékok mint KCNQ káliumcsatorna modulátorok, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények |
| FR2827604B1 (fr) * | 2001-07-17 | 2003-09-19 | Sanofi Synthelabo | Nouveaux derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2- one, un procede pour leur preparation et les compositions pharmaceutiques en contenant |
| GEP20074230B (en) | 2002-03-20 | 2007-11-12 | Bristol Myers Squibb Co | Phosphate prodrugs of fluorooxindoles |
| CA2555812A1 (en) * | 2004-02-13 | 2005-09-01 | President And Fellows Of Harvard College | 3-3-di-substituted-oxindoles as inhibitors of translation initiation |
| NZ550222A (en) * | 2004-04-08 | 2010-09-30 | Topotarget As | Diphenyl ox-indol-2-one compounds and their use in the treatment of cancer |
| US7576082B2 (en) * | 2005-06-24 | 2009-08-18 | Hoffman-La Roche Inc. | Oxindole derivatives |
| CA2684552A1 (en) * | 2007-04-24 | 2008-10-30 | Topotarget A/S | Substituted 3-(4-hydroxyphenyl)-indolin-2-one compounds |
| FR2920023B1 (fr) * | 2007-08-16 | 2013-02-08 | Sanofi Aventis | Derives de l'indol-2-one disubstitues en 3, leur preparation et leur application en therapeutique |
| ES2398676T3 (es) * | 2007-12-07 | 2013-03-20 | Abbott Gmbh & Co. Kg | Derivados de oxindol sustituidos con amidometilo y su uso para la producción de un medicamento para el tratamiento de enfermedades dependientes de la vasopresina |
| HRP20150882T1 (hr) * | 2008-10-17 | 2015-09-25 | Xenon Pharmaceuticals Inc. | Spirooksindolski spojevi i njihova upotreba kao terapijska sredstva |
| US9029080B2 (en) * | 2008-11-06 | 2015-05-12 | Basf Se | Screening assay for insecticides |
| EP2540295A1 (en) * | 2011-06-27 | 2013-01-02 | Centre national de la recherche scientifique | Compositions for the treatment of Fragile X syndrome |
| EP2978757B1 (en) * | 2013-03-27 | 2017-02-08 | Boehringer Ingelheim International GmbH | Indolinone analogues as brd4 inhibitors |
| US20180318285A1 (en) * | 2015-03-10 | 2018-11-08 | President And Fellows Of Harvard College | Methods for treatment of autism spectrum disorders |
| KR102510784B1 (ko) * | 2017-03-30 | 2023-03-15 | 엑스더블유파마 리미티드 | 이환형 헤테로아릴 유도체 및 이의 제조 및 용도 |
| US20220267329A1 (en) * | 2019-03-08 | 2022-08-25 | The University Of Buea | Dihydro-Spiro[Indoline-3:1'-Isoquinolin]-2-Ones and Their Analogues and Derivatives and Methods of Treating Cancer and Other Diseases |
-
2020
- 2020-05-20 EP EP20175820.8A patent/EP3912625A1/en not_active Withdrawn
-
2021
- 2021-05-20 PT PT217271477T patent/PT4153170T/pt unknown
- 2021-05-20 EP EP21727147.7A patent/EP4153170B1/en active Active
- 2021-05-20 KR KR1020227044772A patent/KR20230016194A/ko active Pending
- 2021-05-20 IL IL297493A patent/IL297493A/en unknown
- 2021-05-20 BR BR112022023318A patent/BR112022023318A2/pt unknown
- 2021-05-20 RS RS20260429A patent/RS67993B1/sr unknown
- 2021-05-20 DK DK21727147.7T patent/DK4153170T3/da active
- 2021-05-20 PL PL21727147.7T patent/PL4153170T3/pl unknown
- 2021-05-20 PH PH1/2022/553155A patent/PH12022553155A1/en unknown
- 2021-05-20 SM SM20260144T patent/SMT202600144T1/it unknown
- 2021-05-20 AU AU2021274879A patent/AU2021274879A1/en active Pending
- 2021-05-20 WO PCT/EP2021/063463 patent/WO2021234084A1/en not_active Ceased
- 2021-05-20 JP JP2022571242A patent/JP2023528292A/ja active Pending
- 2021-05-20 HR HRP20260481TT patent/HRP20260481T1/hr unknown
- 2021-05-20 ES ES21727147T patent/ES3065116T3/es active Active
- 2021-05-20 MX MX2022014461A patent/MX2022014461A/es unknown
- 2021-05-20 CA CA3177423A patent/CA3177423A1/en active Pending
- 2021-05-20 US US17/999,400 patent/US20240351994A1/en active Pending
- 2021-05-20 SI SI202130410T patent/SI4153170T1/sl unknown
- 2021-05-20 CN CN202180035813.2A patent/CN115666554A/zh active Pending
- 2021-05-20 LT LTEPPCT/EP2021/063463T patent/LT4153170T/lt unknown
- 2021-05-20 FI FIEP21727147.7T patent/FI4153170T3/fi active
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