JP2023522990A5 - - Google Patents

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Publication number
JP2023522990A5
JP2023522990A5 JP2022564281A JP2022564281A JP2023522990A5 JP 2023522990 A5 JP2023522990 A5 JP 2023522990A5 JP 2022564281 A JP2022564281 A JP 2022564281A JP 2022564281 A JP2022564281 A JP 2022564281A JP 2023522990 A5 JP2023522990 A5 JP 2023522990A5
Authority
JP
Japan
Prior art keywords
compound
pharmaceutically acceptable
acceptable salt
formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022564281A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023522990A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/019285 external-priority patent/WO2021216195A1/en
Publication of JP2023522990A publication Critical patent/JP2023522990A/ja
Publication of JP2023522990A5 publication Critical patent/JP2023522990A5/ja
Priority to JP2025104709A priority Critical patent/JP2025134881A/ja
Pending legal-status Critical Current

Links

JP2022564281A 2020-04-23 2021-02-23 Sarsの治療のための化合物 Pending JP2023522990A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025104709A JP2025134881A (ja) 2020-04-23 2025-06-20 Sarsの治療のための化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063014501P 2020-04-23 2020-04-23
US63/014,501 2020-04-23
US202063120079P 2020-12-01 2020-12-01
US63/120,079 2020-12-01
PCT/US2021/019285 WO2021216195A1 (en) 2020-04-23 2021-02-23 Compounds for the treatment of sars

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025104709A Division JP2025134881A (ja) 2020-04-23 2025-06-20 Sarsの治療のための化合物

Publications (2)

Publication Number Publication Date
JP2023522990A JP2023522990A (ja) 2023-06-01
JP2023522990A5 true JP2023522990A5 (enExample) 2024-02-14

Family

ID=78269813

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022564281A Pending JP2023522990A (ja) 2020-04-23 2021-02-23 Sarsの治療のための化合物
JP2025104709A Pending JP2025134881A (ja) 2020-04-23 2025-06-20 Sarsの治療のための化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025104709A Pending JP2025134881A (ja) 2020-04-23 2025-06-20 Sarsの治療のための化合物

Country Status (10)

Country Link
US (1) US20230159516A1 (enExample)
EP (1) EP4139280A4 (enExample)
JP (2) JP2023522990A (enExample)
KR (1) KR20230005240A (enExample)
CN (1) CN115667209A (enExample)
AU (1) AU2021259145A1 (enExample)
BR (1) BR112022021381A2 (enExample)
CA (1) CA3176370A1 (enExample)
MX (1) MX2022013081A (enExample)
WO (1) WO2021216195A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11124497B1 (en) 2020-04-17 2021-09-21 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
US11174231B1 (en) 2020-06-09 2021-11-16 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
JP2024102382A (ja) * 2021-05-18 2024-07-31 国立研究開発法人国立国際医療研究センター 抗ウイルス活性等の生理活性を有する化合物
WO2022256434A1 (en) * 2021-06-02 2022-12-08 ACEA Therapeutics, Inc. Protease inhibitors as antivirals
US20230033285A1 (en) * 2021-06-16 2023-02-02 The Scripps Research Institute Protease Inhibitors for Treatment of Coronavirus Infections
CN114456211B (zh) * 2021-09-03 2024-03-26 中国药科大学 一种拟肽类化合物及其制备方法和应用
CN115806570B (zh) * 2021-11-15 2023-09-12 南京知和医药科技有限公司 一种拟肽衍生物及其药物组合物和用途
KR20250109233A (ko) * 2022-11-22 2025-07-16 머크 샤프 앤드 돔 엘엘씨 코로나바이러스 감염을 치료 또는 예방하기 위한 프로테아제 억제제로서의 2-아미노-n-(4-아미노-3,4-디옥소-1-(2-옥소피롤리딘-3-일)부탄-2-일)벤즈아미드 유도체

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3507486B2 (ja) 1991-03-15 2004-03-15 アムジエン・インコーポレーテツド 顆粒球コロニー刺激因子の肺内投与
US5451569A (en) 1994-04-19 1995-09-19 Hong Kong University Of Science And Technology R & D Corporation Limited Pulmonary drug delivery system
PA8507801A1 (es) * 1999-12-03 2002-08-26 Agouron Pharma Compuestos y composiciones antipicornavirales, sus usos farmaceuticos y los materiales para su sintesis
WO2004093860A1 (en) * 2003-04-21 2004-11-04 Pfizer Inc. Inhibitors of sars related coronavirus proteinase
EP1704142A4 (en) * 2003-12-31 2008-08-20 Taigen Biotechnology Co Ltd PROTEASE INHIBITORS
WO2006061714A2 (en) * 2004-12-09 2006-06-15 Pfizer Inc. Anticoronaviral compounds and compositions, their pharmaceutical uses and materials for their synthesis
US20110269834A1 (en) * 2008-08-21 2011-11-03 The Board Of Trustees Of The University Of Illinois Compounds and methods for treating respiratory diseases
EP2718261B1 (en) * 2011-06-08 2016-02-24 Nitto Denko Corporation Compounds for targeting drug delivery and enhancing sirna activity
CN102838523A (zh) * 2011-06-23 2012-12-26 南开大学 抗肠病毒71(ev71)戊内酰胺类化合物及其制备方法和用途
CA2850003C (en) * 2011-09-27 2020-01-07 Kansas State University Research Foundation Broad-spectrum antivirals against 3c or 3c-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses
CN103130710B (zh) * 2011-11-29 2015-12-16 南开大学 抗肠病毒71(ev71)己内酰胺醛类化合物及其制备方法和用途
CN106928206B (zh) * 2015-12-31 2022-02-18 中国科学院上海药物研究所 醛基类化合物及其制法和用途
CN110818691A (zh) * 2018-08-09 2020-02-21 中国科学院上海药物研究所 酮酰胺类化合物及其制备方法、药物组合物和用途
BR112021023814A2 (pt) * 2020-06-09 2022-12-20 Pardes Biosciences Inc Inibidores de proteases de cisteína e métodos de uso das mesmas

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