JP2023522841A5 - - Google Patents
Info
- Publication number
- JP2023522841A5 JP2023522841A5 JP2022559980A JP2022559980A JP2023522841A5 JP 2023522841 A5 JP2023522841 A5 JP 2023522841A5 JP 2022559980 A JP2022559980 A JP 2022559980A JP 2022559980 A JP2022559980 A JP 2022559980A JP 2023522841 A5 JP2023522841 A5 JP 2023522841A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- compound
- haloalkyl
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063010108P | 2020-04-15 | 2020-04-15 | |
| US63/010,108 | 2020-04-15 | ||
| PCT/US2021/027538 WO2021211882A1 (en) | 2020-04-15 | 2021-04-15 | Methods for preparing tyrosine receptor kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522841A JP2023522841A (ja) | 2023-06-01 |
| JP2023522841A5 true JP2023522841A5 (https=) | 2024-04-26 |
| JP7767301B2 JP7767301B2 (ja) | 2025-11-11 |
Family
ID=78083713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022559980A Active JP7767301B2 (ja) | 2020-04-15 | 2021-04-15 | チロシン受容体キナーゼ阻害剤を調製する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12606565B2 (https=) |
| EP (1) | EP4135700A4 (https=) |
| JP (1) | JP7767301B2 (https=) |
| KR (1) | KR20230011912A (https=) |
| CN (1) | CN115515591B (https=) |
| AU (1) | AU2021255613A1 (https=) |
| BR (1) | BR112022020114A2 (https=) |
| CA (1) | CA3172681A1 (https=) |
| IL (1) | IL296921A (https=) |
| MX (1) | MX2022012437A (https=) |
| WO (1) | WO2021211882A1 (https=) |
| ZA (1) | ZA202209792B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202005237SA (en) | 2017-12-15 | 2020-07-29 | Pyramid Biosciences Inc | 5-(2-(2,5-difluorophenyl)pyrrolidin-1 -yl)-3-(1h-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine derivatives and related compounds as trk kinase inhibitors for treating cancer |
| IL296921A (en) | 2020-04-15 | 2022-12-01 | Pyramid Biosciences Inc | Methods for making receptor tyrosine kinase inhibitors |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4911920A (en) | 1986-07-30 | 1990-03-27 | Alcon Laboratories, Inc. | Sustained release, comfort formulation for glaucoma therapy |
| FR2588189B1 (fr) | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| JP2594486B2 (ja) | 1991-01-15 | 1997-03-26 | アルコン ラボラトリーズ インコーポレイテッド | 局所的眼薬組成物 |
| US5212162A (en) | 1991-03-27 | 1993-05-18 | Alcon Laboratories, Inc. | Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions |
| CN101242844A (zh) * | 2005-06-10 | 2008-08-13 | 詹森药业有限公司 | 作为激酶调节剂的氨基嘧啶类化合物 |
| UA95244C2 (ru) * | 2005-06-22 | 2011-07-25 | Плексикон, Инк. | Соединения и способ модулирования активности киназ, и показания для их применения |
| WO2008037477A1 (en) | 2006-09-29 | 2008-04-03 | Novartis Ag | Pyrazolopyrimidines as p13k lipid kinase inhibitors |
| KR101324804B1 (ko) | 2008-05-13 | 2013-11-01 | 아이알엠 엘엘씨 | 키나제 억제제로서의 질소 함유 융합 헤테로사이클 및 그의 조성물 |
| MY169791A (en) | 2008-10-22 | 2019-05-15 | Array Biopharma Inc | Substituted pyrazolo [1,5-a] pyrimidine compounds as trk kinase inhibitors |
| EP2348860B1 (en) | 2008-10-31 | 2015-05-27 | Genentech, Inc. | Pyrazolopyrimidine jak inhibitor compounds and methods |
| WO2012022045A1 (en) * | 2010-08-20 | 2012-02-23 | Hutchison Medipharma Limited | Pyrrolopyrimidine compounds and uses thereof |
| EP3812387A1 (en) | 2011-07-21 | 2021-04-28 | Sumitomo Dainippon Pharma Oncology, Inc. | Heterocyclic protein kinase inhibitors |
| WO2014055928A2 (en) * | 2012-10-04 | 2014-04-10 | University Of Utah Research Foundation | Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors |
| FR3029769A1 (fr) | 2014-12-10 | 2016-06-17 | Tornier Sa | Kit pour une prothese d'epaule |
| CA2971024C (en) | 2014-12-15 | 2023-09-26 | Handok Inc. | Fused ring heteroaryl compounds and their use as trk inhibitors |
| AR103297A1 (es) | 2014-12-30 | 2017-05-03 | Forma Therapeutics Inc | Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina |
| JP6475084B2 (ja) | 2015-05-21 | 2019-02-27 | 臼井国際産業株式会社 | トルクセンサ用シャフトの製造設備およびその製造方法 |
| WO2018005533A1 (en) * | 2016-07-01 | 2018-01-04 | G1 Therapeutics, Inc. | Antiproliferative pyrimidine-based compounds |
| SG11202005237SA (en) * | 2017-12-15 | 2020-07-29 | Pyramid Biosciences Inc | 5-(2-(2,5-difluorophenyl)pyrrolidin-1 -yl)-3-(1h-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine derivatives and related compounds as trk kinase inhibitors for treating cancer |
| IL296921A (en) | 2020-04-15 | 2022-12-01 | Pyramid Biosciences Inc | Methods for making receptor tyrosine kinase inhibitors |
-
2021
- 2021-04-15 IL IL296921A patent/IL296921A/en unknown
- 2021-04-15 CN CN202180024618.XA patent/CN115515591B/zh active Active
- 2021-04-15 CA CA3172681A patent/CA3172681A1/en active Pending
- 2021-04-15 WO PCT/US2021/027538 patent/WO2021211882A1/en not_active Ceased
- 2021-04-15 JP JP2022559980A patent/JP7767301B2/ja active Active
- 2021-04-15 KR KR1020227033977A patent/KR20230011912A/ko active Pending
- 2021-04-15 EP EP21787908.9A patent/EP4135700A4/en active Pending
- 2021-04-15 AU AU2021255613A patent/AU2021255613A1/en active Pending
- 2021-04-15 MX MX2022012437A patent/MX2022012437A/es unknown
- 2021-04-15 BR BR112022020114A patent/BR112022020114A2/pt unknown
- 2021-04-15 US US17/918,880 patent/US12606565B2/en active Active
-
2022
- 2022-09-01 ZA ZA2022/09792A patent/ZA202209792B/en unknown
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