JP2023522701A5 - - Google Patents
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- Publication number
- JP2023522701A5 JP2023522701A5 JP2022563451A JP2022563451A JP2023522701A5 JP 2023522701 A5 JP2023522701 A5 JP 2023522701A5 JP 2022563451 A JP2022563451 A JP 2022563451A JP 2022563451 A JP2022563451 A JP 2022563451A JP 2023522701 A5 JP2023522701 A5 JP 2023522701A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063012603P | 2020-04-20 | 2020-04-20 | |
| US63/012,603 | 2020-04-20 | ||
| PCT/US2021/028166 WO2021216556A2 (en) | 2020-04-20 | 2021-04-20 | Oligonucleotides for msh3 modulation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023522701A JP2023522701A (ja) | 2023-05-31 |
| JP2023522701A5 true JP2023522701A5 (https=) | 2024-05-02 |
| JPWO2021216556A5 JPWO2021216556A5 (https=) | 2024-05-02 |
Family
ID=78270051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022563451A Pending JP2023522701A (ja) | 2020-04-20 | 2021-04-20 | Ｍｓｈ３調節のためのオリゴヌクレオチド |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210355491A1 (https=) |
| EP (1) | EP4138860A4 (https=) |
| JP (1) | JP2023522701A (https=) |
| AU (1) | AU2021260581A1 (https=) |
| CA (1) | CA3176204A1 (https=) |
| WO (1) | WO2021216556A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3277811B1 (en) | 2015-04-03 | 2020-12-23 | University of Massachusetts | Fully stabilized asymmetric sirna |
| US10633653B2 (en) | 2015-08-14 | 2020-04-28 | University Of Massachusetts | Bioactive conjugates for oligonucleotide delivery |
| JP7406793B2 (ja) | 2017-06-23 | 2023-12-28 | ユニバーシティー オブ マサチューセッツ | ２テイル自己デリバリー型ｓｉＲＮＡおよび関連方法 |
| JP7627042B2 (ja) | 2018-08-23 | 2025-02-05 | ユニバーシティー オブ マサチューセッツ | Ｏ－メチルリッチ完全安定化オリゴヌクレオチド |
| CN113614232A (zh) | 2019-01-18 | 2021-11-05 | 马萨诸塞大学 | 动态药代动力学修饰锚 |
| MX2022001710A (es) | 2019-08-09 | 2022-05-10 | Univ Massachusetts | Oligonucleótidos modificados químicamente dirigidos a los snp. |
| US12365894B2 (en) | 2019-09-16 | 2025-07-22 | University Of Massachusetts | Branched lipid conjugates of siRNA for specific tissue delivery |
| WO2021226549A1 (en) * | 2020-05-08 | 2021-11-11 | Triplet Therapeutics, Inc. | Methods for the treatment of nucleotide repeat expansion disorders associated with msh3 activity |
| WO2021242883A1 (en) | 2020-05-26 | 2021-12-02 | University Of Massachusetts | Synthetic oligonucleotides having regions of block and cluster modifications |
| AR122534A1 (es) | 2020-06-03 | 2022-09-21 | Triplet Therapeutics Inc | Métodos para el tratamiento de los trastornos de expansión por repetición de nucleótidos asociados con la actividad de msh3 |
| EP4164656A4 (en) * | 2020-06-11 | 2025-10-22 | Ionis Pharmaceuticals Inc | COMPOUNDS AND METHODS FOR REDUCING MSH3 EXPRESSION |
| WO2022212231A2 (en) | 2021-03-29 | 2022-10-06 | Alnylam Pharmaceuticals, Inc. | Huntingtin (htt) irna agent compositions and methods of use thereof |
| WO2023076450A2 (en) * | 2021-10-29 | 2023-05-04 | Alnylam Pharmaceuticals, Inc. | HUNTINGTIN (HTT) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF |
| US20230313198A1 (en) * | 2021-12-17 | 2023-10-05 | University Of Massachusetts | Oligonucleotides for mlh3 modulation |
| US20240035027A1 (en) * | 2022-05-04 | 2024-02-01 | University Of Massachusetts | Oligonucleotides for pms2 modulation |
| AU2023272008A1 (en) * | 2022-05-16 | 2024-12-12 | Atalanta Therapeutics, Inc. | Compositions and methods for treatment of microsatellite dna expansion disorders |
| WO2024064954A2 (en) * | 2022-09-23 | 2024-03-28 | The Children's Hospital Of Philadelphia | Compositions and methods for treating huntington's disease and related disorders |
| WO2025078602A1 (en) * | 2023-10-11 | 2025-04-17 | Uniqure Biopharma B.V. | Nucleic acid regulation of msh3 in repeat expansion disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO974597A0 (en) * | 1997-10-10 | 1997-11-06 | Rhone-Poulenc Agro | Methods for obtaining plant varieties |
| US7361468B2 (en) * | 2004-07-02 | 2008-04-22 | Affymetrix, Inc. | Methods for genotyping polymorphisms in humans |
| WO2013120037A1 (en) * | 2012-02-10 | 2013-08-15 | Regents Of The University Of Minnesota | Dna assimilation |
| WO2015171918A2 (en) * | 2014-05-07 | 2015-11-12 | Louisiana State University And Agricultural And Mechanical College | Compositions and uses for treatment thereof |
| TN2017000354A1 (en) * | 2015-02-10 | 2019-01-16 | Genzyme Corp | VARIANT RNAi |
| SMT202000454T1 (it) * | 2015-04-03 | 2020-11-10 | Univ Massachusetts | Cmposti oligonucleotidici per bersagliare l'mrn della huntingtina |
| US20170009304A1 (en) * | 2015-07-07 | 2017-01-12 | Splicingcodes.Com | Method and kit for detecting fusion transcripts |
| WO2017132669A1 (en) * | 2016-01-31 | 2017-08-03 | University Of Massachusetts | Branched oligonucleotides |
| JP7714162B6 (ja) * | 2018-12-03 | 2025-09-08 | タケダ ファーマシューティカルズ ユーエスエー インコーポレイテッド | Ｍｓｈ３活性に関連するトリヌクレオチドリピート伸長障害の処置のための方法 |
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2021
- 2021-04-20 US US17/235,153 patent/US20210355491A1/en active Pending
- 2021-04-20 EP EP21792058.6A patent/EP4138860A4/en active Pending
- 2021-04-20 WO PCT/US2021/028166 patent/WO2021216556A2/en not_active Ceased
- 2021-04-20 CA CA3176204A patent/CA3176204A1/en active Pending
- 2021-04-20 JP JP2022563451A patent/JP2023522701A/ja active Pending
- 2021-04-20 AU AU2021260581A patent/AU2021260581A1/en active Pending