JP2023520047A5 - - Google Patents
Info
- Publication number
- JP2023520047A5 JP2023520047A5 JP2022559873A JP2022559873A JP2023520047A5 JP 2023520047 A5 JP2023520047 A5 JP 2023520047A5 JP 2022559873 A JP2022559873 A JP 2022559873A JP 2022559873 A JP2022559873 A JP 2022559873A JP 2023520047 A5 JP2023520047 A5 JP 2023520047A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- cationic lipid
- optionally substituted
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025244099A JP2026048786A (ja) | 2020-04-01 | 2025-12-10 | フェノール酸脂質系カチオン性脂質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063003698P | 2020-04-01 | 2020-04-01 | |
| US63/003,698 | 2020-04-01 | ||
| PCT/US2021/025128 WO2021202694A1 (en) | 2020-04-01 | 2021-03-31 | Phenolic acid lipid based cationic lipids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025244099A Division JP2026048786A (ja) | 2020-04-01 | 2025-12-10 | フェノール酸脂質系カチオン性脂質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023520047A JP2023520047A (ja) | 2023-05-15 |
| JP2023520047A5 true JP2023520047A5 (enExample) | 2024-04-11 |
| JP7791103B2 JP7791103B2 (ja) | 2025-12-23 |
Family
ID=75625666
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022559873A Active JP7791103B2 (ja) | 2020-04-01 | 2021-03-31 | フェノール酸脂質系カチオン性脂質 |
| JP2025244099A Pending JP2026048786A (ja) | 2020-04-01 | 2025-12-10 | フェノール酸脂質系カチオン性脂質 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025244099A Pending JP2026048786A (ja) | 2020-04-01 | 2025-12-10 | フェノール酸脂質系カチオン性脂質 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP4126813A1 (enExample) |
| JP (2) | JP7791103B2 (enExample) |
| CN (2) | CN115667207B (enExample) |
| WO (1) | WO2021202694A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4313115A1 (en) | 2021-03-25 | 2024-02-07 | Translate Bio, Inc. | Optimized nucleotide sequences encoding the extracellular domain of human ace2 protein or a portion thereof |
| JP2024515668A (ja) * | 2021-04-19 | 2024-04-10 | トランスレイト バイオ， インコーポレイテッド | Ｍｒｎａの送達のための改善された組成物 |
| US20240398940A1 (en) | 2021-09-03 | 2024-12-05 | CureVac SE | Novel lipid nanoparticles for delivery of nucleic acids |
| EP4422698A1 (en) | 2021-10-29 | 2024-09-04 | CureVac SE | Improved circular rna for expressing therapeutic proteins |
| US20250099614A1 (en) | 2022-01-28 | 2025-03-27 | CureVac SE | Nucleic acid encoded transcription factor inhibitors |
| US20250345407A1 (en) | 2022-05-25 | 2025-11-13 | CureVac SE | Nucleic acid based vaccine encoding an escherichia coli fimh antigenic polypeptide |
| EP4608442A1 (en) | 2022-10-28 | 2025-09-03 | GlaxoSmithKline Biologicals S.A. | Nucleic acid based vaccine |
| EP4637813A1 (en) | 2022-12-20 | 2025-10-29 | Sanofi Pasteur | Rhinovirus mrna vaccine |
| WO2024184500A1 (en) | 2023-03-08 | 2024-09-12 | CureVac SE | Novel lipid nanoparticle formulations for delivery of nucleic acids |
| WO2024230934A1 (en) | 2023-05-11 | 2024-11-14 | CureVac SE | Therapeutic nucleic acid for the treatment of ophthalmic diseases |
| TW202543585A (zh) | 2024-03-08 | 2025-11-16 | 美商健臻公司 | 脂質奈米粒子 |
| WO2026003373A1 (en) | 2024-06-28 | 2026-01-02 | Sanofi | Phenolic acid lipid based cationic lipids |
| WO2026008743A1 (en) | 2024-07-02 | 2026-01-08 | Sanofi Pasteur Inc. | Water-soluble polyanionic polymer as adjuvant for carrier-formulated nucleic acid |
| WO2026030375A2 (en) | 2024-07-30 | 2026-02-05 | Genzyme Corporation | Lipid nanoparticles and methods of manufacture and use thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4500707A (en) | 1980-02-29 | 1985-02-19 | University Patents, Inc. | Nucleosides useful in the preparation of polynucleotides |
| US5132418A (en) | 1980-02-29 | 1992-07-21 | University Patents, Inc. | Process for preparing polynucleotides |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| US4668777A (en) | 1981-03-27 | 1987-05-26 | University Patents, Inc. | Phosphoramidite nucleoside compounds |
| US4973679A (en) | 1981-03-27 | 1990-11-27 | University Patents, Inc. | Process for oligonucleo tide synthesis using phosphormidite intermediates |
| US4401796A (en) | 1981-04-30 | 1983-08-30 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
| US4373071A (en) | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
| US5153319A (en) | 1986-03-31 | 1992-10-06 | University Patents, Inc. | Process for preparing polynucleotides |
| US5262530A (en) | 1988-12-21 | 1993-11-16 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| US5047524A (en) | 1988-12-21 | 1991-09-10 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
| US5885613A (en) | 1994-09-30 | 1999-03-23 | The University Of British Columbia | Bilayer stabilizing components and their use in forming programmable fusogenic liposomes |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US5700642A (en) | 1995-05-22 | 1997-12-23 | Sri International | Oligonucleotide sizing using immobilized cleavable primers |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| WO1999052894A1 (en) * | 1998-04-09 | 1999-10-21 | Meiji Seika Kaisha, Ltd. | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof |
| JP6557722B2 (ja) * | 2014-05-30 | 2019-08-07 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 核酸の送達のための生分解性脂質 |
| PL3386484T3 (pl) * | 2015-12-10 | 2022-07-25 | Modernatx, Inc. | Kompozycje i sposoby dostarczania środków terapeutycznych |
| JP2019519601A (ja) | 2016-05-18 | 2019-07-11 | モダーナティエックス・インコーポレイテッドＭｏｄｅｒｎａＴＸ， Ｉｎｃ． | 急性間欠性ポルフィリン症の治療のためのポルホビリノゲン脱アミノ酵素をコードするポリヌクレオチド |
| AU2017357758B2 (en) | 2016-11-10 | 2023-11-16 | Translate Bio, Inc. | Improved process of preparing mRNA-loaded lipid nanoparticles |
| EP4186888B1 (en) | 2017-03-15 | 2025-11-26 | ModernaTX, Inc. | Compound and compositions for intracellular delivery of therapeutic agents |
| JP7488193B2 (ja) * | 2018-05-24 | 2024-05-21 | トランスレイト バイオ， インコーポレイテッド | チオエステルカチオン性脂質 |
| EP3849617A1 (en) * | 2018-09-14 | 2021-07-21 | Translate Bio, Inc. | Composition and methods for treatment of methylmalonic acidemia |
| CN110526885A (zh) * | 2019-08-20 | 2019-12-03 | 上海英诺富成生物科技有限公司 | 麦考酚酸的前体药物及其制备方法 |
-
2021
- 2021-03-31 CN CN202180039080.XA patent/CN115667207B/zh active Active
- 2021-03-31 WO PCT/US2021/025128 patent/WO2021202694A1/en not_active Ceased
- 2021-03-31 EP EP21720636.6A patent/EP4126813A1/en active Pending
- 2021-03-31 CN CN202511243318.7A patent/CN121318756A/zh active Pending
- 2021-03-31 JP JP2022559873A patent/JP7791103B2/ja active Active
-
2025
- 2025-12-10 JP JP2025244099A patent/JP2026048786A/ja active Pending
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