JP2023519266A5 - - Google Patents

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Publication number
JP2023519266A5
JP2023519266A5 JP2022557797A JP2022557797A JP2023519266A5 JP 2023519266 A5 JP2023519266 A5 JP 2023519266A5 JP 2022557797 A JP2022557797 A JP 2022557797A JP 2022557797 A JP2022557797 A JP 2022557797A JP 2023519266 A5 JP2023519266 A5 JP 2023519266A5
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JP
Japan
Prior art keywords
alkyl
aryl
group
cycloalkyl
alkenyl
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JP2022557797A
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English (en)
Japanese (ja)
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JP2023519266A (ja
JP7542644B2 (ja
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Priority claimed from PCT/IB2021/000163 external-priority patent/WO2021191680A1/en
Publication of JP2023519266A publication Critical patent/JP2023519266A/ja
Publication of JP2023519266A5 publication Critical patent/JP2023519266A5/ja
Application granted granted Critical
Publication of JP7542644B2 publication Critical patent/JP7542644B2/ja
Active legal-status Critical Current
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JP2022557797A 2020-03-24 2021-03-24 チアミンの類似体及び誘導体と結合するアプタマー Active JP7542644B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062994135P 2020-03-24 2020-03-24
US62/994,135 2020-03-24
PCT/IB2021/000163 WO2021191680A1 (en) 2020-03-24 2021-03-24 Aptamers that bind thiamine analogs and derivatives

Publications (3)

Publication Number Publication Date
JP2023519266A JP2023519266A (ja) 2023-05-10
JP2023519266A5 true JP2023519266A5 (https=) 2024-04-03
JP7542644B2 JP7542644B2 (ja) 2024-08-30

Family

ID=75888083

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022557797A Active JP7542644B2 (ja) 2020-03-24 2021-03-24 チアミンの類似体及び誘導体と結合するアプタマー

Country Status (12)

Country Link
US (1) US12570988B2 (https=)
EP (1) EP4127176A1 (https=)
JP (1) JP7542644B2 (https=)
KR (1) KR102879552B1 (https=)
CN (1) CN115698292A (https=)
AU (1) AU2021243743B2 (https=)
BR (1) BR112022019284A2 (https=)
CA (1) CA3172864A1 (https=)
IL (1) IL296711B2 (https=)
MX (1) MX2022011940A (https=)
PH (1) PH12022552557A1 (https=)
WO (1) WO2021191680A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3239306A1 (en) * 2021-12-15 2023-06-22 Xuecui GUO Aptamers and small molecule ligands
CN117417301A (zh) * 2022-01-26 2024-01-19 上海日馨医药科技股份有限公司 含硫类化合物、其药物组合物及应用
EP4599064A1 (en) * 2022-10-07 2025-08-13 Okinawa Institute of Science and Technology School Corporation An rna aptamer that binds to asp7967 or an analogue thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2614150A1 (en) 2010-09-07 2013-07-17 Yeda Research and Development Co. Ltd. Thiamine pyrophosphate (tpp) riboswitch mutants producing vitamin b1 enriched food and feed crops
KR102699584B1 (ko) 2015-02-02 2024-08-28 메이라지티엑스 유케이 Ii 리미티드 대안적 스플라이싱의 압타머 매개 조절에 의한 유전자 발현 제어
ES2954929T3 (es) 2016-02-02 2023-11-27 Meiragtx Uk Ii Ltd Regulación de expresión génica mediante control mediado por aptámeros de ribozimas de autocorte
AU2017213835C1 (en) 2016-02-02 2024-04-18 MeiraGTx Gene Regulation Limited Regulation of gene expression through aptamer-modulated polyadenylation
ES3024480T3 (en) 2017-02-21 2025-06-04 Meiragtx Uk Ii Ltd Regulation of gene expression by aptamer-mediated accessibility of polyadenylation signals
SG11201908043UA (en) 2017-03-02 2019-09-27 Meiragtx Uk Ii Limited Regulation of gene expression by aptamer-modulated rnase p cleavage

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