JP2024546954A5 - - Google Patents

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Publication number
JP2024546954A5
JP2024546954A5 JP2024535970A JP2024535970A JP2024546954A5 JP 2024546954 A5 JP2024546954 A5 JP 2024546954A5 JP 2024535970 A JP2024535970 A JP 2024535970A JP 2024535970 A JP2024535970 A JP 2024535970A JP 2024546954 A5 JP2024546954 A5 JP 2024546954A5
Authority
JP
Japan
Prior art keywords
nucleotide
aptamer
sequence encoding
sequence
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024535970A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546954A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/000762 external-priority patent/WO2023111686A2/en
Publication of JP2024546954A publication Critical patent/JP2024546954A/ja
Publication of JP2024546954A5 publication Critical patent/JP2024546954A5/ja
Pending legal-status Critical Current

Links

JP2024535970A 2021-12-15 2022-12-15 アプタマー及び小分子リガンド Pending JP2024546954A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163361400P 2021-12-15 2021-12-15
US63/361,400 2021-12-15
PCT/IB2022/000762 WO2023111686A2 (en) 2021-12-15 2022-12-15 Aptamers and small molecule ligands

Publications (2)

Publication Number Publication Date
JP2024546954A JP2024546954A (ja) 2024-12-26
JP2024546954A5 true JP2024546954A5 (https=) 2025-12-22

Family

ID=85511135

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024535970A Pending JP2024546954A (ja) 2021-12-15 2022-12-15 アプタマー及び小分子リガンド

Country Status (10)

Country Link
US (1) US20250101436A1 (https=)
EP (1) EP4448769A2 (https=)
JP (1) JP2024546954A (https=)
KR (1) KR20240133703A (https=)
CN (1) CN118786217A (https=)
AU (1) AU2022409938A1 (https=)
CA (1) CA3239306A1 (https=)
IL (1) IL313463A (https=)
MX (1) MX2024007448A (https=)
WO (1) WO2023111686A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2024305450A1 (en) 2023-06-14 2026-01-22 MeiraGTx Gene Regulation Limited Small molecule ligands and aptamers
WO2025027580A1 (en) 2023-08-01 2025-02-06 Meiragtx Uk Ii Limited Riboswitch-regulated expression of chimeric antigen receptors
WO2025212263A1 (en) * 2024-04-05 2025-10-09 The University Of North Carolina At Chapel Hill Quinoxaline containing rna-targeting ligands, compositions thereof, and methods of making and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2614150A1 (en) * 2010-09-07 2013-07-17 Yeda Research and Development Co. Ltd. Thiamine pyrophosphate (tpp) riboswitch mutants producing vitamin b1 enriched food and feed crops
KR102699584B1 (ko) * 2015-02-02 2024-08-28 메이라지티엑스 유케이 Ii 리미티드 대안적 스플라이싱의 압타머 매개 조절에 의한 유전자 발현 제어
ES2954929T3 (es) * 2016-02-02 2023-11-27 Meiragtx Uk Ii Ltd Regulación de expresión génica mediante control mediado por aptámeros de ribozimas de autocorte
SG11201908043UA (en) * 2017-03-02 2019-09-27 Meiragtx Uk Ii Limited Regulation of gene expression by aptamer-modulated rnase p cleavage
BR112022019284A2 (pt) * 2020-03-24 2023-02-14 Meiragtx Uk Ii Ltd Aptâmeros que se ligam a análogos e derivados de tiamina

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