JP2023511686A5 - - Google Patents

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Publication number
JP2023511686A5
JP2023511686A5 JP2022545136A JP2022545136A JP2023511686A5 JP 2023511686 A5 JP2023511686 A5 JP 2023511686A5 JP 2022545136 A JP2022545136 A JP 2022545136A JP 2022545136 A JP2022545136 A JP 2022545136A JP 2023511686 A5 JP2023511686 A5 JP 2023511686A5
Authority
JP
Japan
Prior art keywords
renal
antigen
acid sequence
binding fragment
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022545136A
Other languages
English (en)
Japanese (ja)
Other versions
JP7706458B2 (ja
JP2023511686A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/051753 external-priority patent/WO2021151889A1/en
Publication of JP2023511686A publication Critical patent/JP2023511686A/ja
Publication of JP2023511686A5 publication Critical patent/JP2023511686A5/ja
Application granted granted Critical
Publication of JP7706458B2 publication Critical patent/JP7706458B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022545136A 2020-01-27 2021-01-26 腎疾患の治療に使用するための抗αvβ8インテグリン抗体 Active JP7706458B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062966258P 2020-01-27 2020-01-27
US62/966,258 2020-01-27
PCT/EP2021/051753 WO2021151889A1 (en) 2020-01-27 2021-01-26 ANTI-αVβ8 INTEGRIN ANTIBODIES FOR USE IN TREATING KIDNEY DISEASE

Publications (3)

Publication Number Publication Date
JP2023511686A JP2023511686A (ja) 2023-03-22
JP2023511686A5 true JP2023511686A5 (https=) 2024-01-23
JP7706458B2 JP7706458B2 (ja) 2025-07-11

Family

ID=74561850

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022545136A Active JP7706458B2 (ja) 2020-01-27 2021-01-26 腎疾患の治療に使用するための抗αvβ8インテグリン抗体

Country Status (18)

Country Link
US (1) US20230112035A1 (https=)
EP (1) EP4096785A1 (https=)
JP (1) JP7706458B2 (https=)
KR (1) KR20220132567A (https=)
CN (1) CN115151305A (https=)
AR (1) AR121193A1 (https=)
AU (1) AU2021213403B2 (https=)
BR (1) BR112022014633A2 (https=)
CA (1) CA3167390A1 (https=)
CL (1) CL2022001999A1 (https=)
CO (1) CO2022011661A2 (https=)
CR (1) CR20220392A (https=)
EC (1) ECSP22066085A (https=)
IL (1) IL294814A (https=)
MX (1) MX2022009165A (https=)
PH (1) PH12022551863A1 (https=)
TW (1) TWI854088B (https=)
WO (1) WO2021151889A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7654539B2 (ja) 2018-09-07 2025-04-01 ファイザー・インク 抗αvβ8抗体、組成物及びその使用
EP4587473A1 (en) 2022-09-12 2025-07-23 Institut National de la Santé et de la Recherche Médicale New anti-itgb8 antibodies and its uses thereof
CN120936626A (zh) * 2023-03-31 2025-11-11 基因泰克公司 抗αvβ8整合素抗体及使用方法
CN117143241B (zh) * 2023-10-26 2024-02-23 迈威(上海)生物科技股份有限公司 与人整合素蛋白itgav/itgb8特异性结合的单克隆抗体
CN117126282B (zh) * 2023-10-26 2024-01-12 迈威(上海)生物科技股份有限公司 抗体及其在制备阻断αvβ8与Latent TGF-β的结合的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
AU2011217848B8 (en) 2010-02-18 2015-09-24 The Regents Of The University Of California Integrin aVB8 neutralizing antibody
KR102010098B1 (ko) * 2011-08-17 2019-08-13 더 리전트 오브 더 유니버시티 오브 캘리포니아 인테그린 알파-v 베타-8에 결합하는 항체
EP3139957A4 (en) * 2014-05-06 2018-04-25 Scholar Rock, Inc. Compositions and methods for growth factor modulation
SI3157561T1 (sl) 2014-06-17 2020-08-31 Medlmmune Limited Izboljšana protitelesa alfa-V beta-8
EP3634485A4 (en) * 2017-06-07 2021-07-21 Silverback Therapeutics, Inc. CONJUGATES OF ANTIBODIES CONTAINING IMMUNOMODULATOR COMPOUNDS AND THEIR USES
AU2019318538B2 (en) * 2018-08-08 2025-02-06 The General Hospital Corporation Polypeptide integrin antagonists

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