|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
EP1690934A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5562909A
(en)
|
1993-07-12 |
1996-10-08 |
Massachusetts Institute Of Technology |
Phosphazene polyelectrolytes as immunoadjuvants
|
|
WO1995006477A1
(en)
|
1993-08-31 |
1995-03-09 |
Gliatech, Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
EP0815134B1
(en)
|
1995-03-14 |
2002-06-05 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
|
WO1997021728A1
(en)
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6071493A
(en)
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US6043283A
(en)
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
US7588766B1
(en)
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
NZ540564A
(en)
|
1999-11-29 |
2007-04-27 |
Neurochem Int Ltd |
Vaccine for the prevention and treatment of Alzheimer's and amyloid related diseases
|
|
BRPI0108676B8
(pt)
|
2000-02-24 |
2021-05-25 |
Lilly Co Eli |
anticorpos humanizados que sequestram peptídeo amilóide beta e seus usos no tratamento de condições caracterizadas por formação de placas amiloides, bem como composição farmacêutica que compreende os referidos anticorpos
|
|
AU2007234495A1
(en)
|
2000-09-08 |
2007-12-06 |
Board Of Regents, The University Of Texas System |
Biopanning and rapid analysis of selective interactive ligands (BRASIL)
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
JP2005501220A
(ja)
|
2000-12-19 |
2005-01-13 |
パラチン テクノロジーズ インク． |
ペプチドおよび蛋白質の標的特異的折りたたみ部位の識別
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
CA2487528A1
(en)
|
2002-07-24 |
2004-02-12 |
Innogenetics N.V. |
Prevention, treatment and diagnosis of diseases associated with beta-amyloid formation and/or aggregation
|
|
WO2010011999A2
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
EP1585520A1
(en)
|
2002-12-24 |
2005-10-19 |
Neurochem (International) Limited |
Therapeutic formulations for the treatment of beta-amyloid related diseases
|
|
DE602004027348D1
(de)
|
2003-02-10 |
2010-07-08 |
Applied Molecular Evolution |
Abeta-bindende moleküle
|
|
CN1795207A
(zh)
*
|
2003-03-28 |
2006-06-28 |
森托科尔公司 |
抗淀粉状蛋白抗体、组合物、方法和用途
|
|
PE20050627A1
(es)
|
2003-05-30 |
2005-08-10 |
Wyeth Corp |
Anticuerpos humanizados que reconocen el peptido beta amiloideo
|
|
CA2538076A1
(en)
|
2003-09-12 |
2005-03-24 |
The Regents Of The University Of California |
Monoclonal antibodies specific for conformational epitopes of prefibrillar aggregates
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
US20050267029A1
(en)
|
2004-04-02 |
2005-12-01 |
Ancsin John B |
Compounds which modulate amyloidogenesis and methods for their identification and use
|
|
TW200636066A
(en)
|
2004-12-15 |
2006-10-16 |
Elan Pharm Inc |
Humanized antibodies that recognize beta amyloid peptide
|
|
WO2006066089A1
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Humanized amyloid beta antibodies for use in improving cognition
|
|
EP1676859A1
(en)
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
EP1893576A4
(en)
|
2005-05-27 |
2010-03-17 |
Univ Kingston |
TREATMENT OF PROTEIN DISORDERING
|
|
US8067372B2
(en)
|
2005-11-10 |
2011-11-29 |
Alzheimer's Institute Of America, Inc. |
Modulation of angiogenesis by A-beta peptide fragments
|
|
UA99097C2
(ru)
|
2005-12-12 |
2012-07-25 |
Ф. Хоффманн-Ля Рош Аг |
Композиция, содержащая антитела к амилоиду бета 4, имеющие гликозилированный вариабельный участок
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
KR20150002879A
(ko)
|
2006-10-02 |
2015-01-07 |
에이씨 이뮨 에스.에이. |
아밀로이드 베타에 대해 인간화된 항체
|
|
PT2121754E
(pt)
|
2007-01-18 |
2015-05-11 |
Lilly Co Eli |
Fab de beta-amilóide peguilado
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
EP2527366B1
(en)
|
2007-06-12 |
2017-08-16 |
AC Immune S.A. |
Monoclonal anti beta amyloid antibody
|
|
PL2170389T3
(pl)
*
|
2007-06-12 |
2015-03-31 |
Ac Immune Sa |
Humanizowane przeciwciało przeciw amyloidowi beta
|
|
PT2182983E
(pt)
|
2007-07-27 |
2014-09-01 |
Janssen Alzheimer Immunotherap |
Tratamento de doenças amiloidogénicas com anticorpos anti-abeta humanizados
|
|
SG178809A1
(en)
|
2007-10-05 |
2012-03-29 |
Genentech Inc |
Use of anti-amyloid beta antibody in ocular diseases
|
|
CA2701788C
(en)
|
2007-10-05 |
2017-06-13 |
Genentech, Inc. |
Humanized beta-amyloid antibody for treating ocular diseases
|
|
US20090246191A1
(en)
|
2007-10-11 |
2009-10-01 |
University Of Tennessee Research Foundation |
Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
US8343493B2
(en)
|
2007-10-29 |
2013-01-01 |
Innogenetics N.V. |
Antibodies specific of the β-amyloid peptides and their uses as diagnostic agents or drugs
|
|
DK2207568T3
(en)
|
2007-11-16 |
2017-09-18 |
Univ Rockefeller |
ANTIBODIES SPECIFIC TO THE PROTOFIBRILE FORM OF BETA AMYLOID PROTEIN
|
|
DK2237803T3
(en)
|
2007-12-28 |
2015-10-05 |
Prothena Biosciences Ltd |
Treatment and prophylaxis of amyloidosis
|
|
WO2009143489A2
(en)
|
2008-05-22 |
2009-11-26 |
Archer Pharmaceuticals, Inc. |
Modulation of angiogenesis by a-beta peptide fragments
|
|
AT506819B1
(de)
*
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
AT506820B1
(de)
|
2008-06-12 |
2011-07-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzine gegen alzheimer-krankheit
|
|
RU2011100127A
(ru)
|
2008-06-12 |
2012-07-20 |
Аффирис Аг (At) |
Соединение, содержащее пептид, для лечения симптомов болезни паркинсона
|
|
US9045555B2
(en)
|
2008-07-01 |
2015-06-02 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vaccine against amyloid folding intermediate
|
|
US9801865B2
(en)
|
2008-09-24 |
2017-10-31 |
The United States Of America As Represented By The Department Of Veteran Affairs |
Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
|
|
AU2009301580B2
(en)
|
2008-10-06 |
2015-11-26 |
The University Of British Columbia |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
CN102459335B
(zh)
*
|
2009-04-17 |
2015-11-25 |
伊缪纳斯制药株式会社 |
特异性结合Aβ寡聚体的抗体及其用途
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
ES2624835T3
(es)
|
2009-08-06 |
2017-07-17 |
Immunas Pharma, Inc. |
Anticuerpos que se unen específicamente a los oligómeros A beta y uso de los mismos
|
|
CN102597233B
(zh)
*
|
2009-08-07 |
2014-10-29 |
协和发酵麒麟株式会社 |
人源化抗淀粉样-b寡聚体抗体
|
|
EP2478365A1
(en)
|
2009-09-18 |
2012-07-25 |
Probiodrug AG |
Novel assay for the detection of amyloid beta peptides
|
|
CA2789963C
(en)
|
2010-02-26 |
2019-09-03 |
Bioarctic Neuroscience Ab |
Protofibril-binding antibodies and their use in therapeutic and diagnostic methods for parkinson's disease, dementia with lewy bodies and other alpha-synucleinopathies
|
|
RU2644335C2
(ru)
|
2010-03-03 |
2018-02-08 |
Зе Юниверсити Оф Бритиш Коламбия |
Эпитоп, специфичный к олигомеру амилоида бета, и антитела
|
|
PH12012502079A1
(en)
|
2010-04-16 |
2013-02-11 |
Ac Immune Sa |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
EP2377860A1
(en)
|
2010-04-16 |
2011-10-19 |
AC Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
CN103298833B
(zh)
|
2010-08-14 |
2015-12-16 |
Abbvie公司 |
β淀粉样蛋白结合蛋白
|
|
WO2012051498A2
(en)
|
2010-10-15 |
2012-04-19 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
US20120321694A1
(en)
|
2010-10-27 |
2012-12-20 |
Daniel Larocque |
Compositions and uses
|
|
FR2966827B1
(fr)
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
EP2511296A1
(en)
|
2011-04-12 |
2012-10-17 |
Araclón Biotech, S. L. |
Antibody, kit and method for determination of amyloid peptides
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
CN104093454A
(zh)
|
2011-11-10 |
2014-10-08 |
坎格尼美国股份有限公司 |
治疗阿耳茨海默氏病的组合物和方法
|
|
EP2659908A1
(en)
|
2012-05-01 |
2013-11-06 |
Affiris AG |
Compositions
|
|
CA2885924C
(en)
|
2012-08-21 |
2022-12-13 |
Institute For Molecular Medicine, Inc. |
Compositions and methods related to diseases associated with deposits of amyloid, tau, and alpha-synuclein
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
WO2015017900A1
(en)
|
2013-08-05 |
2015-02-12 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
AU2014312215B2
(en)
*
|
2013-08-28 |
2020-02-27 |
Abbvie Stemcentrx Llc |
Site-specific antibody conjugation methods and compositions
|
|
EP3102611A4
(en)
|
2014-02-03 |
2017-08-23 |
Cangene Corporation |
Humanized beta-amyloid binding molecules and uses thereof
|
|
US10501733B2
(en)
*
|
2015-02-27 |
2019-12-10 |
University Of Washington |
Polypeptide assemblies and methods for the production thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
SI3334431T1
(sl)
|
2015-08-11 |
2020-01-31 |
Novartis Ag |
5-bromo-2,6-di-(1h-pirazol-l-il)pyrimidin-4-amin za uporabo v zdravljenju raka
|
|
CA3004496A1
(en)
|
2015-11-09 |
2017-05-18 |
Neil R. Cashman |
Epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
US10759837B2
(en)
|
2015-11-09 |
2020-09-01 |
The University Of British Columbia |
Anti-amyloid beta antibodies binding to a cyclic amyloid beta peptide
|
|
JP6952351B2
(ja)
|
2015-11-09 |
2021-10-20 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
集団座標バイアシングによりミスフォールディングタンパク質エピトープを予測するためのシステムおよび方法
|
|
CA3004494A1
(en)
*
|
2015-11-09 |
2017-05-18 |
The University Of British Columiba |
Epitopes in amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
US10772969B2
(en)
|
2015-11-09 |
2020-09-15 |
The University Of British Columbia |
N-terminal epitopes in amyloid beta and conformationally-selective antibodies thereto
|
|
EP3374380A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
C-terminal epitopes in amyloid-beta and conformation-sensitive antibodies
|
|
CN109476729A
(zh)
|
2016-07-18 |
2019-03-15 |
英属哥伦比亚大学 |
淀粉样蛋白β的抗体
|
|
US20180125920A1
(en)
*
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|