JP2023511616A5 - - Google Patents
Info
- Publication number
- JP2023511616A5 JP2023511616A5 JP2022545799A JP2022545799A JP2023511616A5 JP 2023511616 A5 JP2023511616 A5 JP 2023511616A5 JP 2022545799 A JP2022545799 A JP 2022545799A JP 2022545799 A JP2022545799 A JP 2022545799A JP 2023511616 A5 JP2023511616 A5 JP 2023511616A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- tautomer
- stereoisomer
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20154031 | 2020-01-28 | ||
| EP20154031.7 | 2020-01-28 | ||
| PCT/EP2021/051697 WO2021151865A1 (en) | 2020-01-28 | 2021-01-26 | Modulators of the integrated stress response pathway |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023511616A JP2023511616A (ja) | 2023-03-20 |
| JP2023511616A5 true JP2023511616A5 (https=) | 2024-02-02 |
| JP7699595B2 JP7699595B2 (ja) | 2025-06-27 |
Family
ID=69374193
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545799A Active JP7699595B2 (ja) | 2020-01-28 | 2021-01-26 | 統合的ストレス応答経路の調節因子 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230125481A1 (https=) |
| EP (1) | EP4096665A1 (https=) |
| JP (1) | JP7699595B2 (https=) |
| KR (1) | KR20220133252A (https=) |
| CN (1) | CN114980894B (https=) |
| AU (1) | AU2021213289A1 (https=) |
| BR (1) | BR112022012643A2 (https=) |
| CA (1) | CA3162526A1 (https=) |
| IL (1) | IL294805A (https=) |
| MX (1) | MX2022009243A (https=) |
| WO (1) | WO2021151865A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| US12091392B2 (en) | 2019-02-13 | 2024-09-17 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| MA54953A (fr) * | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| MX2022011143A (es) | 2020-03-11 | 2022-10-13 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| US20230391763A1 (en) | 2020-10-22 | 2023-12-07 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| JP2023546224A (ja) | 2020-10-22 | 2023-11-01 | エヴォテック・インターナショナル・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 統合ストレス応答経路のモジュレーター |
| MX2023004623A (es) | 2020-10-22 | 2023-05-12 | Evotec Int Gmbh | Moduladores de la via integrada de respuesta al estres. |
| WO2024109736A1 (zh) * | 2022-11-21 | 2024-05-30 | 深圳众格生物科技有限公司 | 一种化合物、包含其的药物组合物及其合成方法和用途 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4033412A1 (de) | 1990-10-20 | 1992-04-23 | Bayer Ag | Fungizide mittel auf basis von heterocyclisch substituierten sulfonen |
| JP6806562B2 (ja) | 2013-03-15 | 2021-01-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ｅＩＦ２α経路の調節因子 |
| EP3082805B1 (en) * | 2013-12-20 | 2020-02-05 | Institute for Drug Discovery, LLC | Substituted amino triazoles, and methods using same |
| TW201808888A (zh) | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808903A (zh) | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TW201808914A (zh) | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| TWI763668B (zh) | 2016-05-05 | 2022-05-11 | 美商嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| CA3026982A1 (en) | 2016-06-08 | 2017-12-14 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| AU2017279027A1 (en) | 2016-06-08 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Chemical Compounds |
| WO2018225093A1 (en) | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds as atf4 pathway inhibitors |
| CN110896634A (zh) | 2017-07-03 | 2020-03-20 | 葛兰素史密斯克莱知识产权发展有限公司 | 作为atf4抑制剂用于治疗癌症和其它疾病的2-(4-氯苯氧基)-n-((1-(2-(4-氯苯氧基)乙炔氮杂环丁烷-3-基)甲基)乙酰胺衍生物和相关化合物 |
| US20210145771A1 (en) | 2017-07-03 | 2021-05-20 | Glaxosmithkline Intellectual Property Development Limited | N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1] pentan-1-yl)-2-cyclobutane-1- carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases |
| CN118239937A (zh) | 2017-08-09 | 2024-06-25 | 戴纳立制药公司 | 化合物、组合物及方法 |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| EP3704125B1 (en) | 2017-11-02 | 2026-03-11 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| US11939320B2 (en) | 2017-11-02 | 2024-03-26 | Abbvie Inc. | Modulators of the integrated stress pathway |
| EP3704096B1 (en) | 2017-11-02 | 2026-04-22 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37958A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37957A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CA3080804A1 (en) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| EP3704098B1 (en) | 2017-11-02 | 2024-01-24 | Calico Life Sciences LLC | Modulators of the integrated stress pathway |
| SG11202004009TA (en) | 2017-11-02 | 2020-05-28 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| WO2019118785A2 (en) | 2017-12-13 | 2019-06-20 | Praxis Biotech LLC | Inhibitors of integrated stress response pathway |
| WO2019183589A1 (en) | 2018-03-23 | 2019-09-26 | Denali Therapeutics Inc. | Modulators of eukaryotic initiation factor 2 |
| WO2019193540A1 (en) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Heteroaryl derivatives of formula (i) as atf4 inhibitors |
| WO2019193541A1 (en) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors |
-
2021
- 2021-01-26 AU AU2021213289A patent/AU2021213289A1/en active Pending
- 2021-01-26 WO PCT/EP2021/051697 patent/WO2021151865A1/en not_active Ceased
- 2021-01-26 CA CA3162526A patent/CA3162526A1/en active Pending
- 2021-01-26 US US17/759,490 patent/US20230125481A1/en active Pending
- 2021-01-26 IL IL294805A patent/IL294805A/en unknown
- 2021-01-26 KR KR1020227029412A patent/KR20220133252A/ko active Pending
- 2021-01-26 JP JP2022545799A patent/JP7699595B2/ja active Active
- 2021-01-26 CN CN202180011613.3A patent/CN114980894B/zh active Active
- 2021-01-26 MX MX2022009243A patent/MX2022009243A/es unknown
- 2021-01-26 BR BR112022012643A patent/BR112022012643A2/pt unknown
- 2021-01-26 EP EP21702218.5A patent/EP4096665A1/en active Pending
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