CN114980894B - 整合应激反应途径的调节剂 - Google Patents

整合应激反应途径的调节剂 Download PDF

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CN114980894B
CN114980894B CN202180011613.3A CN202180011613A CN114980894B CN 114980894 B CN114980894 B CN 114980894B CN 202180011613 A CN202180011613 A CN 202180011613A CN 114980894 B CN114980894 B CN 114980894B
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compound
chloro
pharmaceutically acceptable
oxadiazol
acetamide
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CN114980894A (zh
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C·J·布朗
J·L·卡尔
M·沙巴
J·M·施克瑞安茨
D·S·沃尔特
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Evertec International Co ltd
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Evertec International Co ltd
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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CN202180011613.3A 2020-01-28 2021-01-26 整合应激反应途径的调节剂 Active CN114980894B (zh)

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CN115190813B (zh) 2020-03-11 2024-10-15 埃沃特克国际有限责任公司 整合应激反应途径的调节剂
EP4232153A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
RS66455B1 (sr) 2020-10-22 2025-02-28 Evotec Int Gmbh Modulatori puta integrisanog odgovora na stres
EP4232447A1 (en) 2020-10-22 2023-08-30 Evotec International GmbH Modulators of the integrated stress response pathway
AU2023384649A1 (en) * 2022-11-21 2025-05-22 Shenzhen Zhongge Biological Technology Co., Ltd. Compound, pharmaceutical composition containing same, synthesis method therefor and use thereof

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CN114980894A (zh) 2022-08-30
JP7699595B2 (ja) 2025-06-27
KR20220133252A (ko) 2022-10-04
AU2021213289A1 (en) 2022-07-07
BR112022012643A2 (pt) 2022-09-06
WO2021151865A1 (en) 2021-08-05
CA3162526A1 (en) 2021-08-05
EP4096665A1 (en) 2022-12-07
MX2022009243A (es) 2022-08-16
IL294805A (en) 2022-09-01
JP2023511616A (ja) 2023-03-20
US20230125481A1 (en) 2023-04-27

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