JP2023502843A5 - - Google Patents

Info

Publication number
JP2023502843A5
JP2023502843A5 JP2022519139A JP2022519139A JP2023502843A5 JP 2023502843 A5 JP2023502843 A5 JP 2023502843A5 JP 2022519139 A JP2022519139 A JP 2022519139A JP 2022519139 A JP2022519139 A JP 2022519139A JP 2023502843 A5 JP2023502843 A5 JP 2023502843A5
Authority
JP
Japan
Prior art keywords
sequence
fusion polypeptide
cancer
amino acid
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022519139A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023502843A (ja
Filing date
Publication date
Priority claimed from GB201913804A external-priority patent/GB201913804D0/en
Application filed filed Critical
Publication of JP2023502843A publication Critical patent/JP2023502843A/ja
Publication of JP2023502843A5 publication Critical patent/JP2023502843A5/ja
Pending legal-status Critical Current

Links

JP2022519139A 2019-09-25 2020-09-25 癌を処置するために使用されるil-15融合ペプチド Pending JP2023502843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1913804.9 2019-09-25
GB201913804A GB201913804D0 (en) 2019-09-25 2019-09-25 Fusion polypeptides
PCT/GB2020/052328 WO2021058973A1 (en) 2019-09-25 2020-09-25 Il-15 fusion peptides used to treat cancer

Publications (2)

Publication Number Publication Date
JP2023502843A JP2023502843A (ja) 2023-01-26
JP2023502843A5 true JP2023502843A5 (enExample) 2023-09-28

Family

ID=68425465

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022519139A Pending JP2023502843A (ja) 2019-09-25 2020-09-25 癌を処置するために使用されるil-15融合ペプチド

Country Status (9)

Country Link
US (1) US20220372097A1 (enExample)
EP (1) EP4034552A1 (enExample)
JP (1) JP2023502843A (enExample)
CN (1) CN114651014A (enExample)
AU (1) AU2020351698A1 (enExample)
CA (1) CA3155100A1 (enExample)
GB (1) GB201913804D0 (enExample)
IL (1) IL291560A (enExample)
WO (1) WO2021058973A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
GB202304385D0 (en) 2023-03-24 2023-05-10 Prostate Cancer Res Combinatorial IL-15 therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
GB9614871D0 (en) 1996-07-15 1996-09-04 Smithkline Beecham Plc Compounds
US20070160578A1 (en) * 2005-12-14 2007-07-12 The Gov. Of The Usa As Represented By The Secretary Of The Dep. Of Health And Human Services Expansion of natural killer and CD8 T-cells with IL-15R/ligand activator complexes
GB0915519D0 (en) 2009-09-04 2009-10-07 King S College London Ntithrombotic compounds
WO2012054509A2 (en) * 2010-10-22 2012-04-26 Dana-Farber Cancer Institute, Inc. Discovery of regulatory t cells programmed to suppress an immune response
WO2018161026A1 (en) * 2017-03-03 2018-09-07 Obsidian Therapeutics, Inc. Il15 compositions and methods for immunotherapy
WO2019006472A1 (en) * 2017-06-30 2019-01-03 Xencor, Inc. TARGETED HETETRODIMERIC FUSION PROTEINS CONTAINING IL-15 / IL-15RA AND ANTIGEN-BINDING DOMAINS
CA3086040A1 (en) * 2017-12-19 2019-06-27 Blaze Bioscience, Inc. Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof
AU2019228381B2 (en) * 2018-02-28 2021-12-16 Pfizer Inc. IL-15 variants and uses thereof
CA3090407A1 (en) * 2018-03-01 2019-09-06 Glycotope Gmbh Fusion protein constructs comprising an anti-muc1 antibody and il-15

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