JP2023171766A5 - - Google Patents
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- JP2023171766A5 JP2023171766A5 JP2023145605A JP2023145605A JP2023171766A5 JP 2023171766 A5 JP2023171766 A5 JP 2023171766A5 JP 2023145605 A JP2023145605 A JP 2023145605A JP 2023145605 A JP2023145605 A JP 2023145605A JP 2023171766 A5 JP2023171766 A5 JP 2023171766A5
- Authority
- JP
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- Prior art keywords
- cells
- medium
- population
- natural killer
- culturing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000012258 culturing Methods 0.000 claims description 42
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- 239000003795 chemical substances by application Substances 0.000 claims description 36
- 238000000034 method Methods 0.000 claims description 36
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562242246P | 2015-10-15 | 2015-10-15 | |
| US62/242,246 | 2015-10-15 | ||
| US201562272984P | 2015-12-30 | 2015-12-30 | |
| US62/272,984 | 2015-12-30 | ||
| US201662403571P | 2016-10-03 | 2016-10-03 | |
| US62/403,571 | 2016-10-03 | ||
| JP2018519316A JP2018535666A (ja) | 2015-10-15 | 2016-10-14 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
| PCT/US2016/056988 WO2017066530A1 (en) | 2015-10-15 | 2016-10-14 | Natural killer cells and ilc3 cells and uses thereof |
| JP2021171231A JP2022023148A (ja) | 2015-10-15 | 2021-10-19 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021171231A Division JP2022023148A (ja) | 2015-10-15 | 2021-10-19 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023171766A JP2023171766A (ja) | 2023-12-05 |
| JP2023171766A5 true JP2023171766A5 (https=) | 2024-04-04 |
Family
ID=58517926
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519316A Pending JP2018535666A (ja) | 2015-10-15 | 2016-10-14 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
| JP2021171231A Pending JP2022023148A (ja) | 2015-10-15 | 2021-10-19 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
| JP2023145605A Pending JP2023171766A (ja) | 2015-10-15 | 2023-09-07 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519316A Pending JP2018535666A (ja) | 2015-10-15 | 2016-10-14 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
| JP2021171231A Pending JP2022023148A (ja) | 2015-10-15 | 2021-10-19 | ナチュラルキラー細胞およびｉｌｃ３細胞ならびにそれらの使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20180346877A1 (https=) |
| EP (1) | EP3362075B1 (https=) |
| JP (3) | JP2018535666A (https=) |
| KR (1) | KR20180059555A (https=) |
| CN (1) | CN109310710A (https=) |
| AU (1) | AU2016340005B2 (https=) |
| BR (1) | BR112018007538A2 (https=) |
| CA (1) | CA3002066A1 (https=) |
| CO (1) | CO2018004937A2 (https=) |
| EA (1) | EA201890960A1 (https=) |
| IL (1) | IL258666B2 (https=) |
| MX (1) | MX2018004600A (https=) |
| MY (1) | MY201637A (https=) |
| NZ (1) | NZ741612A (https=) |
| SG (2) | SG10201912576PA (https=) |
| TW (1) | TW201732037A (https=) |
| WO (1) | WO2017066530A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| WO2019067792A1 (en) * | 2017-09-28 | 2019-04-04 | Celularity, Inc. | TUMOR CONTROL WITH INTERMEDIATE NATURAL KILLER CELLS DERIVED FROM HUMAN PLACENTA (PINK) IN COMBINATION WITH ANTIBODY |
| CN112135618A (zh) * | 2018-02-20 | 2020-12-25 | 蒙特利尔大学 | 体内介导免疫应答的nk和dc细胞的扩增 |
| CN108486054B (zh) * | 2018-04-12 | 2022-04-19 | 平安爱普德（北京）生物技术有限公司 | 一种体外扩增i型天然细胞毒性淋巴细胞ilc1/nk的方法 |
| AU2019387491A1 (en) * | 2018-11-30 | 2021-05-27 | Celularity Inc. | Expansion of natural killer cells and ILC3 cells with novel aromatic compounds |
| WO2020231200A1 (ko) * | 2019-05-15 | 2020-11-19 | 오정훈 | 효율적 자연살해세포 배양방법 및 이의 배지첨가 키트 |
| US20220265712A1 (en) * | 2019-06-14 | 2022-08-25 | Celularity Inc. | Populations of natural killer cells for treating cancers |
| JP2022542321A (ja) * | 2019-07-29 | 2022-09-30 | デヴェラ セラピューティクス インコーポレイテッド | 免疫療法のためのｎｋ細胞組成物および調製物ならびにそれらの製造のための方法 |
| EP4076466B1 (en) * | 2019-12-18 | 2026-03-11 | Universite De Montreal | Modulators of cullin 3 adaptor kbtbd4 as anti-cancer compounds |
| US20220000919A1 (en) * | 2020-01-29 | 2022-01-06 | Celularity Inc. | Placental derived natural killer cells for treatment of coronavirus infections |
| US12195759B2 (en) * | 2020-02-21 | 2025-01-14 | FullHope Biomedical Co., Ltd. | Modified natural killer cells, pharmaceutical composition, manufacturing method thereof, and method of using the same |
| JP7793284B2 (ja) * | 2020-03-02 | 2026-01-05 | 株式会社ガイアバイオメディシン | 高活性ｎｋ細胞の処理方法 |
| KR20220048775A (ko) * | 2020-10-13 | 2022-04-20 | 주식회사 노보셀바이오 | Nk 세포를 유효성분으로 포함하는 항바이러스 조성물 |
| CN112285083B (zh) * | 2020-10-28 | 2022-01-07 | 上海睿钰生物科技有限公司 | 一种细胞杀伤效力的评价方法 |
| CN112251406B (zh) * | 2020-10-30 | 2023-06-09 | 曹峰林 | 一种nk细胞活化阶段的外泌体分选方法 |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| JPWO2023038037A1 (https=) * | 2021-09-08 | 2023-03-16 | ||
| WO2025028596A1 (ja) * | 2023-08-02 | 2025-02-06 | 株式会社ヘリオス | ナチュラルキラー細胞の製造方法 |
| CN117511867B (zh) * | 2023-10-07 | 2024-08-06 | 深圳泽医细胞治疗集团有限公司 | 一种靶向肺部且高表达nkg2d的nk细胞的培养试剂盒及其应用 |
Family Cites Families (13)
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|---|---|---|---|---|
| US5709859A (en) * | 1991-01-24 | 1998-01-20 | Bristol-Myers Squibb Company | Mixed specificity fusion proteins |
| PE20100362A1 (es) * | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
| WO2012075412A1 (en) * | 2010-12-03 | 2012-06-07 | Michael Verneris | Generation of natural killer cells and lymphoid tissue inducer-like (lti-like) nk-22 cells |
| WO2012128622A1 (en) * | 2011-03-18 | 2012-09-27 | Ipd-Therapeutics B.V. | Generation of nk cells and nk-cell progenitors |
| EP2807165B1 (en) * | 2012-01-27 | 2019-05-15 | Université de Montréal | Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells |
| DK2812011T3 (da) | 2012-02-08 | 2020-02-24 | Glycostem Therapeutics B V | Differentiering ex vivo af nk-celler fra cd34+ hæmatopoietiske celler |
| JP2015526088A (ja) * | 2012-08-13 | 2015-09-10 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞及びその使用 |
| US9074186B2 (en) * | 2012-08-15 | 2015-07-07 | Boston Medical Center Corporation | Production of red blood cells and platelets from stem cells |
| EP3041494A4 (en) * | 2013-09-05 | 2017-10-18 | Sanford-Burnham Medical Research Institute | Modulation of gamma delta t cells |
| KR102308597B1 (ko) * | 2013-10-17 | 2021-10-01 | 내셔널 유니버시티 오브 싱가포르 | 다중 종양에 대항하여 항체-의존성 세포 세포독성을 촉발시키는 키메라 수용체 |
| BR112017014269A2 (pt) * | 2014-12-31 | 2018-03-27 | Anthrogenesis Corp | células exterminadoras naturais e usos das mesmas |
| EP3350316B1 (en) | 2015-09-15 | 2024-05-08 | Stichting Radboud universitair medisch centrum | IMPROVED METHOD FOR EX VIVO EXPANSION CD34+HSPCs INTO NK CELLS USING AN ARYL HYDROCARBON RECEPTOR ANTAGONIST |
| BR112018072701A2 (pt) * | 2016-05-07 | 2019-02-19 | Celularity, Inc. | métodos de tratamento de leucemia mieloide aguda e mieloma múltiplo usando células exterminadoras naturais |
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2016
- 2016-10-14 EA EA201890960A patent/EA201890960A1/ru unknown
- 2016-10-14 EP EP16856249.4A patent/EP3362075B1/en active Active
- 2016-10-14 US US15/768,505 patent/US20180346877A1/en not_active Abandoned
- 2016-10-14 NZ NZ741612A patent/NZ741612A/en not_active IP Right Cessation
- 2016-10-14 CN CN201680074724.8A patent/CN109310710A/zh active Pending
- 2016-10-14 TW TW105133346A patent/TW201732037A/zh unknown
- 2016-10-14 KR KR1020187013666A patent/KR20180059555A/ko not_active Ceased
- 2016-10-14 AU AU2016340005A patent/AU2016340005B2/en not_active Ceased
- 2016-10-14 WO PCT/US2016/056988 patent/WO2017066530A1/en not_active Ceased
- 2016-10-14 SG SG10201912576PA patent/SG10201912576PA/en unknown
- 2016-10-14 CA CA3002066A patent/CA3002066A1/en active Pending
- 2016-10-14 BR BR112018007538A patent/BR112018007538A2/pt not_active Application Discontinuation
- 2016-10-14 SG SG11201803117YA patent/SG11201803117YA/en unknown
- 2016-10-14 JP JP2018519316A patent/JP2018535666A/ja active Pending
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2018
- 2018-05-09 CO CONC2018/0004937A patent/CO2018004937A2/es unknown
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2021
- 2021-10-19 JP JP2021171231A patent/JP2022023148A/ja active Pending
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2022
- 2022-11-16 US US18/056,088 patent/US20230142803A1/en active Pending
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2023
- 2023-09-07 JP JP2023145605A patent/JP2023171766A/ja active Pending
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