CO2018004937A2 - Células asesinas naturales y células ilc3 y usos de las mismas - Google Patents

Células asesinas naturales y células ilc3 y usos de las mismas

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Publication number
CO2018004937A2
CO2018004937A2 CONC2018/0004937A CO2018004937A CO2018004937A2 CO 2018004937 A2 CO2018004937 A2 CO 2018004937A2 CO 2018004937 A CO2018004937 A CO 2018004937A CO 2018004937 A2 CO2018004937 A2 CO 2018004937A2
Authority
CO
Colombia
Prior art keywords
cells
ilc3
methods
natural killer
ilc3 cells
Prior art date
Application number
CONC2018/0004937A
Other languages
English (en)
Spanish (es)
Inventor
Robert J Hariri
Eric Law
Xiaokui Zhang
Ivana Djuretic
Lin Kang
Vanessa Voskinarian-Berse
Bhavani Stout
Wolfgang Hofgartner
James Edinger
Vladimir Jankovic
Original Assignee
Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of CO2018004937A2 publication Critical patent/CO2018004937A2/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61K40/42—Cancer antigens
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Biomedical Technology (AREA)
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  • Wood Science & Technology (AREA)
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  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
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CONC2018/0004937A 2015-10-15 2018-05-09 Células asesinas naturales y células ilc3 y usos de las mismas CO2018004937A2 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562242246P 2015-10-15 2015-10-15
US201562272984P 2015-12-30 2015-12-30
US201662403571P 2016-10-03 2016-10-03
PCT/US2016/056988 WO2017066530A1 (en) 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof

Publications (1)

Publication Number Publication Date
CO2018004937A2 true CO2018004937A2 (es) 2018-09-28

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ID=58517926

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CONC2018/0004937A CO2018004937A2 (es) 2015-10-15 2018-05-09 Células asesinas naturales y células ilc3 y usos de las mismas

Country Status (17)

Country Link
US (2) US20180346877A1 (https=)
EP (1) EP3362075B1 (https=)
JP (3) JP2018535666A (https=)
KR (1) KR20180059555A (https=)
CN (1) CN109310710A (https=)
AU (1) AU2016340005B2 (https=)
BR (1) BR112018007538A2 (https=)
CA (1) CA3002066A1 (https=)
CO (1) CO2018004937A2 (https=)
EA (1) EA201890960A1 (https=)
IL (1) IL258666B2 (https=)
MX (1) MX2018004600A (https=)
MY (1) MY201637A (https=)
NZ (1) NZ741612A (https=)
SG (2) SG10201912576PA (https=)
TW (1) TW201732037A (https=)
WO (1) WO2017066530A1 (https=)

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CA3077325A1 (en) * 2017-09-28 2019-04-04 Celularity Inc. Tumor suppression using human placenta-derived intermediate natural killer (pink) cells in combination with an antibody
US12011460B2 (en) 2018-02-20 2024-06-18 Universite De Montreal Expansion of NK and DC cells in vivo mediating immune response
CN108486054B (zh) * 2018-04-12 2022-04-19 平安爱普德（北京）生物技术有限公司 一种体外扩增i型天然细胞毒性淋巴细胞ilc1/nk的方法
CN113454207A (zh) * 2018-11-30 2021-09-28 细胞结构公司 用新型芳香族化合物扩增自然杀伤细胞和ilc3细胞
WO2020231200A1 (ko) * 2019-05-15 2020-11-19 오정훈 효율적 자연살해세포 배양방법 및 이의 배지첨가 키트
WO2020252464A1 (en) * 2019-06-14 2020-12-17 Celularity Inc. Populations of natural killer cells for treating cancers
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AU2020409437A1 (en) * 2019-12-18 2022-07-14 Universite De Montreal Modulators of Cullin 3 adaptor KBTBD4 as anti-cancer compounds
WO2021155312A1 (en) * 2020-01-29 2021-08-05 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
US12195759B2 (en) 2020-02-21 2025-01-14 FullHope Biomedical Co., Ltd. Modified natural killer cells, pharmaceutical composition, manufacturing method thereof, and method of using the same
JP7793284B2 (ja) * 2020-03-02 2026-01-05 株式会社ガイアバイオメディシン 高活性ｎｋ細胞の処理方法
KR20220048775A (ko) * 2020-10-13 2022-04-20 주식회사 노보셀바이오 Nk 세포를 유효성분으로 포함하는 항바이러스 조성물
CN112285083B (zh) * 2020-10-28 2022-01-07 上海睿钰生物科技有限公司 一种细胞杀伤效力的评价方法
CN112251406B (zh) * 2020-10-30 2023-06-09 曹峰林 一种nk细胞活化阶段的外泌体分选方法
US11591381B2 (en) 2020-11-30 2023-02-28 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
KR20240063899A (ko) * 2021-09-08 2024-05-10 가부시키가이샤 가이아바이오메디신 세포의 처리 방법
WO2025028596A1 (ja) * 2023-08-02 2025-02-06 株式会社ヘリオス ナチュラルキラー細胞の製造方法
CN117511867B (zh) * 2023-10-07 2024-08-06 深圳泽医细胞治疗集团有限公司 一种靶向肺部且高表达nkg2d的nk细胞的培养试剂盒及其应用

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