NZ741612A - Natural killer cells and ilc3 cells and uses thereof - Google Patents

Natural killer cells and ilc3 cells and uses thereof

Info

Publication number
NZ741612A
NZ741612A NZ741612A NZ74161216A NZ741612A NZ 741612 A NZ741612 A NZ 741612A NZ 741612 A NZ741612 A NZ 741612A NZ 74161216 A NZ74161216 A NZ 74161216A NZ 741612 A NZ741612 A NZ 741612A
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NZ
New Zealand
Prior art keywords
cells
medium
population
culturing
days
Prior art date
Application number
NZ741612A
Other languages
English (en)
Inventor
Robert Hariri
Lin Kang
Eric Law
Bhavani Stout
Vanessa Voskinarian-Berse
Xiaokui Zhang
Ivana Djuretic
Wolfgang Hofgartner
James Edinger
Vladimir Jankovic
Original Assignee
Celularity Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celularity Inc filed Critical Celularity Inc
Publication of NZ741612A publication Critical patent/NZ741612A/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
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    • A61K40/42—Cancer antigens
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
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    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2501/20—Cytokines; Chemokines
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
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  • Wood Science & Technology (AREA)
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  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
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NZ741612A 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof NZ741612A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562242246P 2015-10-15 2015-10-15
US201562272984P 2015-12-30 2015-12-30
US201662403571P 2016-10-03 2016-10-03
PCT/US2016/056988 WO2017066530A1 (en) 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof

Publications (1)

Publication Number Publication Date
NZ741612A true NZ741612A (en) 2022-12-23

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ID=58517926

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ741612A NZ741612A (en) 2015-10-15 2016-10-14 Natural killer cells and ilc3 cells and uses thereof

Country Status (17)

Country Link
US (2) US20180346877A1 (https=)
EP (1) EP3362075B1 (https=)
JP (3) JP2018535666A (https=)
KR (1) KR20180059555A (https=)
CN (1) CN109310710A (https=)
AU (1) AU2016340005B2 (https=)
BR (1) BR112018007538A2 (https=)
CA (1) CA3002066A1 (https=)
CO (1) CO2018004937A2 (https=)
EA (1) EA201890960A1 (https=)
IL (1) IL258666B2 (https=)
MX (1) MX2018004600A (https=)
MY (1) MY201637A (https=)
NZ (1) NZ741612A (https=)
SG (2) SG10201912576PA (https=)
TW (1) TW201732037A (https=)
WO (1) WO2017066530A1 (https=)

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TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
WO2019067792A1 (en) * 2017-09-28 2019-04-04 Celularity, Inc. TUMOR CONTROL WITH INTERMEDIATE NATURAL KILLER CELLS DERIVED FROM HUMAN PLACENTA (PINK) IN COMBINATION WITH ANTIBODY
CN112135618A (zh) * 2018-02-20 2020-12-25 蒙特利尔大学 体内介导免疫应答的nk和dc细胞的扩增
CN108486054B (zh) * 2018-04-12 2022-04-19 平安爱普德（北京）生物技术有限公司 一种体外扩增i型天然细胞毒性淋巴细胞ilc1/nk的方法
AU2019387491A1 (en) * 2018-11-30 2021-05-27 Celularity Inc. Expansion of natural killer cells and ILC3 cells with novel aromatic compounds
WO2020231200A1 (ko) * 2019-05-15 2020-11-19 오정훈 효율적 자연살해세포 배양방법 및 이의 배지첨가 키트
US20220265712A1 (en) * 2019-06-14 2022-08-25 Celularity Inc. Populations of natural killer cells for treating cancers
JP2022542321A (ja) * 2019-07-29 2022-09-30 デヴェラ セラピューティクス インコーポレイテッド 免疫療法のためのｎｋ細胞組成物および調製物ならびにそれらの製造のための方法
EP4076466B1 (en) * 2019-12-18 2026-03-11 Universite De Montreal Modulators of cullin 3 adaptor kbtbd4 as anti-cancer compounds
US20220000919A1 (en) * 2020-01-29 2022-01-06 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
US12195759B2 (en) * 2020-02-21 2025-01-14 FullHope Biomedical Co., Ltd. Modified natural killer cells, pharmaceutical composition, manufacturing method thereof, and method of using the same
JP7793284B2 (ja) * 2020-03-02 2026-01-05 株式会社ガイアバイオメディシン 高活性ｎｋ細胞の処理方法
KR20220048775A (ko) * 2020-10-13 2022-04-20 주식회사 노보셀바이오 Nk 세포를 유효성분으로 포함하는 항바이러스 조성물
CN112285083B (zh) * 2020-10-28 2022-01-07 上海睿钰生物科技有限公司 一种细胞杀伤效力的评价方法
CN112251406B (zh) * 2020-10-30 2023-06-09 曹峰林 一种nk细胞活化阶段的外泌体分选方法
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
JPWO2023038037A1 (https=) * 2021-09-08 2023-03-16
WO2025028596A1 (ja) * 2023-08-02 2025-02-06 株式会社ヘリオス ナチュラルキラー細胞の製造方法
CN117511867B (zh) * 2023-10-07 2024-08-06 深圳泽医细胞治疗集团有限公司 一种靶向肺部且高表达nkg2d的nk细胞的培养试剂盒及其应用

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