JP2018502115A5 - - Google Patents
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- JP2018502115A5 JP2018502115A5 JP2017534937A JP2017534937A JP2018502115A5 JP 2018502115 A5 JP2018502115 A5 JP 2018502115A5 JP 2017534937 A JP2017534937 A JP 2017534937A JP 2017534937 A JP2017534937 A JP 2017534937A JP 2018502115 A5 JP2018502115 A5 JP 2018502115A5
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- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims description 2
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462098560P | 2014-12-31 | 2014-12-31 | |
| US62/098,560 | 2014-12-31 | ||
| PCT/US2015/068055 WO2016109661A1 (en) | 2014-12-31 | 2015-12-30 | Natural killer cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213684A Division JP2021072786A (ja) | 2014-12-31 | 2020-12-23 | ナチュラルキラー細胞及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018502115A JP2018502115A (ja) | 2018-01-25 |
| JP2018502115A5 true JP2018502115A5 (https=) | 2019-02-21 |
Family
ID=56285039
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534937A Pending JP2018502115A (ja) | 2014-12-31 | 2015-12-30 | ナチュラルキラー細胞及びその使用 |
| JP2020213684A Pending JP2021072786A (ja) | 2014-12-31 | 2020-12-23 | ナチュラルキラー細胞及びその使用 |
| JP2022176993A Pending JP2023022037A (ja) | 2014-12-31 | 2022-11-04 | ナチュラルキラー細胞及びその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020213684A Pending JP2021072786A (ja) | 2014-12-31 | 2020-12-23 | ナチュラルキラー細胞及びその使用 |
| JP2022176993A Pending JP2023022037A (ja) | 2014-12-31 | 2022-11-04 | ナチュラルキラー細胞及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20180008637A1 (https=) |
| EP (1) | EP3240552A4 (https=) |
| JP (3) | JP2018502115A (https=) |
| KR (2) | KR20230146101A (https=) |
| CN (1) | CN107405364A (https=) |
| AU (2) | AU2015374055A1 (https=) |
| BR (1) | BR112017014269A2 (https=) |
| CA (1) | CA2972662A1 (https=) |
| EA (1) | EA201791443A1 (https=) |
| IL (1) | IL253248A0 (https=) |
| NZ (1) | NZ733213A (https=) |
| WO (1) | WO2016109661A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2948544A4 (en) | 2013-01-28 | 2016-08-03 | St Jude Childrens Res Hospital | CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES |
| DK3143134T3 (da) | 2014-05-15 | 2021-01-04 | Nat Univ Singapore | Modificerede, naturlige dræberceller og anvendelser deraf |
| EP3350316B1 (en) * | 2015-09-15 | 2024-05-08 | Stichting Radboud universitair medisch centrum | IMPROVED METHOD FOR EX VIVO EXPANSION CD34+HSPCs INTO NK CELLS USING AN ARYL HYDROCARBON RECEPTOR ANTAGONIST |
| EA201890960A1 (ru) * | 2015-10-15 | 2018-10-31 | Селулэрити, Инк. | Натуральные киллеры и клетки ilc3 и их применение |
| US20200179341A1 (en) * | 2016-11-04 | 2020-06-11 | Ohio State Innovation Foundation | Methods and compositions for treating multiple myeloma and increasing antibody dependent cell cytotoxicity by targeting the aryl hydrocarbon receptor |
| JP2020503043A (ja) * | 2016-12-30 | 2020-01-30 | セルラリティ インコーポレイテッド | 遺伝子改変されたナチュラルキラー細胞 |
| BR112019019917A2 (pt) | 2017-03-27 | 2020-04-22 | Nat Univ Singapore | receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais |
| CA3056591A1 (en) | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
| BR112020003116A2 (pt) * | 2017-08-17 | 2020-08-04 | Ikena Oncology, Inc. | inibidores de ahr e usos dos mesmos |
| KR102167548B1 (ko) * | 2017-09-21 | 2020-10-19 | 한국생명공학연구원 | 자연살해세포의 제조방법 및 그의 용도 |
| WO2019059713A2 (ko) * | 2017-09-21 | 2019-03-28 | 한국생명공학연구원 | 자연살해세포의 제조방법 및 그의 용도 |
| EP3749685A4 (en) | 2018-02-09 | 2021-12-22 | National University of Singapore | ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY |
| CN112135618A (zh) * | 2018-02-20 | 2020-12-25 | 蒙特利尔大学 | 体内介导免疫应答的nk和dc细胞的扩增 |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| KR20210016567A (ko) | 2018-05-30 | 2021-02-16 | 글리코스템 떼라퓨틱스 비.브이. | Car nk 세포 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| US20220025327A1 (en) * | 2018-10-01 | 2022-01-27 | Universiteit Gent | Accelerated human hematopoeitic stem cell differentiation towards mature natural killer cells with enhanced antibody-dependent cytotoxic activity |
| CN109294985B (zh) * | 2018-10-25 | 2022-02-18 | 江苏普瑞康生物医药科技有限公司 | 一种用于nk细胞体外扩增的培养基体系及nk细胞体外扩增的方法 |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| AU2019387491A1 (en) * | 2018-11-30 | 2021-05-27 | Celularity Inc. | Expansion of natural killer cells and ILC3 cells with novel aromatic compounds |
| WO2020124256A1 (en) * | 2018-12-21 | 2020-06-25 | Stemcell Technologies Canada Inc. | Media and methods for differentiating natural killer cells |
| JP7335001B2 (ja) * | 2019-01-18 | 2023-08-29 | アセポディア バイオテクノロジーズ リミテッド | 新規ｃｄ１６＋ナチュラルキラーおよびｃｄ１６＋ナチュラルキラー細胞の培養方法 |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| KR102298639B1 (ko) * | 2019-03-28 | 2021-09-07 | 한국생명공학연구원 | 면역세포의 제조방법 및 그의 용도 |
| CN110079529A (zh) * | 2019-04-28 | 2019-08-02 | 成都美杰赛尔生物科技有限公司 | 用于靶向敲除人NKG2A/KLRC1基因的sgRNA、表达载体、试剂盒及其用途 |
| US20220265712A1 (en) * | 2019-06-14 | 2022-08-25 | Celularity Inc. | Populations of natural killer cells for treating cancers |
| CN113652393B (zh) * | 2020-05-12 | 2023-08-15 | 内蒙古大学 | 一种提高牛胚胎干细胞多能性的方法 |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CN113046314B (zh) * | 2021-03-30 | 2022-11-25 | 中国科学技术大学 | 一种人脐血或骨髓造血干细胞体外诱导扩增蜕膜样自然杀伤细胞的方法 |
| CN113337466B (zh) * | 2021-07-13 | 2023-03-24 | 杭州原生生物科技有限公司 | 一种无血清nk分化培养基及其制备方法 |
| CN115381959A (zh) * | 2022-09-30 | 2022-11-25 | 上海纳米技术及应用国家工程研究中心有限公司 | 一种治疗肝癌的联合用药 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2666746T3 (es) * | 2010-07-13 | 2018-05-07 | Anthrogenesis Corporation | Métodos para generar linfocitos citolíticos naturales |
| EP2807165B1 (en) * | 2012-01-27 | 2019-05-15 | Université de Montréal | Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells |
| DK2812011T3 (da) * | 2012-02-08 | 2020-02-24 | Glycostem Therapeutics B V | Differentiering ex vivo af nk-celler fra cd34+ hæmatopoietiske celler |
| US9175266B2 (en) * | 2012-07-23 | 2015-11-03 | Gamida Cell Ltd. | Enhancement of natural killer (NK) cell proliferation and activity |
| JP2015526088A (ja) * | 2012-08-13 | 2015-09-10 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞及びその使用 |
-
2015
- 2015-12-30 BR BR112017014269A patent/BR112017014269A2/pt not_active Application Discontinuation
- 2015-12-30 KR KR1020237033327A patent/KR20230146101A/ko not_active Ceased
- 2015-12-30 EA EA201791443A patent/EA201791443A1/ru unknown
- 2015-12-30 EP EP15876255.9A patent/EP3240552A4/en not_active Withdrawn
- 2015-12-30 KR KR1020177021038A patent/KR20170098938A/ko not_active Ceased
- 2015-12-30 US US15/541,004 patent/US20180008637A1/en not_active Abandoned
- 2015-12-30 WO PCT/US2015/068055 patent/WO2016109661A1/en not_active Ceased
- 2015-12-30 CA CA2972662A patent/CA2972662A1/en active Pending
- 2015-12-30 JP JP2017534937A patent/JP2018502115A/ja active Pending
- 2015-12-30 CN CN201580077231.5A patent/CN107405364A/zh active Pending
- 2015-12-30 AU AU2015374055A patent/AU2015374055A1/en not_active Abandoned
- 2015-12-30 NZ NZ733213A patent/NZ733213A/en not_active IP Right Cessation
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2017
- 2017-06-29 IL IL253248A patent/IL253248A0/en unknown
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2020
- 2020-05-18 US US16/876,979 patent/US20200330516A1/en not_active Abandoned
- 2020-12-23 JP JP2020213684A patent/JP2021072786A/ja active Pending
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2021
- 2021-12-06 AU AU2021282387A patent/AU2021282387A1/en not_active Abandoned
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2022
- 2022-11-04 JP JP2022176993A patent/JP2023022037A/ja active Pending
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