JP2018502115A5 - - Google Patents

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Publication number
JP2018502115A5
JP2018502115A5 JP2017534937A JP2017534937A JP2018502115A5 JP 2018502115 A5 JP2018502115 A5 JP 2018502115A5 JP 2017534937 A JP2017534937 A JP 2017534937A JP 2017534937 A JP2017534937 A JP 2017534937A JP 2018502115 A5 JP2018502115 A5 JP 2018502115A5
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Japan
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medium
concentration
present
cells
substituents
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JP2017534937A
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English (en)
Japanese (ja)
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JP2018502115A (ja
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Priority claimed from PCT/US2015/068055 external-priority patent/WO2016109661A1/en
Publication of JP2018502115A publication Critical patent/JP2018502115A/ja
Publication of JP2018502115A5 publication Critical patent/JP2018502115A5/ja
Pending legal-status Critical Current

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JP2017534937A 2014-12-31 2015-12-30 ナチュラルキラー細胞及びその使用 Pending JP2018502115A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462098560P 2014-12-31 2014-12-31
US62/098,560 2014-12-31
PCT/US2015/068055 WO2016109661A1 (en) 2014-12-31 2015-12-30 Natural killer cells and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020213684A Division JP2021072786A (ja) 2014-12-31 2020-12-23 ナチュラルキラー細胞及びその使用

Publications (2)

Publication Number Publication Date
JP2018502115A JP2018502115A (ja) 2018-01-25
JP2018502115A5 true JP2018502115A5 (https=) 2019-02-21

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017534937A Pending JP2018502115A (ja) 2014-12-31 2015-12-30 ナチュラルキラー細胞及びその使用
JP2020213684A Pending JP2021072786A (ja) 2014-12-31 2020-12-23 ナチュラルキラー細胞及びその使用
JP2022176993A Pending JP2023022037A (ja) 2014-12-31 2022-11-04 ナチュラルキラー細胞及びその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2020213684A Pending JP2021072786A (ja) 2014-12-31 2020-12-23 ナチュラルキラー細胞及びその使用
JP2022176993A Pending JP2023022037A (ja) 2014-12-31 2022-11-04 ナチュラルキラー細胞及びその使用

Country Status (12)

Country Link
US (2) US20180008637A1 (https=)
EP (1) EP3240552A4 (https=)
JP (3) JP2018502115A (https=)
KR (2) KR20230146101A (https=)
CN (1) CN107405364A (https=)
AU (2) AU2015374055A1 (https=)
BR (1) BR112017014269A2 (https=)
CA (1) CA2972662A1 (https=)
EA (1) EA201791443A1 (https=)
IL (1) IL253248A0 (https=)
NZ (1) NZ733213A (https=)
WO (1) WO2016109661A1 (https=)

Families Citing this family (32)

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EP2948544A4 (en) 2013-01-28 2016-08-03 St Jude Childrens Res Hospital CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
AU2015259877B2 (en) 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
EP3350316B1 (en) * 2015-09-15 2024-05-08 Stichting Radboud universitair medisch centrum IMPROVED METHOD FOR EX VIVO EXPANSION CD34+HSPCs INTO NK CELLS USING AN ARYL HYDROCARBON RECEPTOR ANTAGONIST
MY201637A (en) * 2015-10-15 2024-03-06 Celularity Inc Natural killer cells and ilc3 cells and uses thereof
WO2018085775A1 (en) * 2016-11-04 2018-05-11 Ohio State Innovation Foundation Methods and compositions for treating multiple myeloma and increasing antibody dependent cell cytotoxicity by targeting the aryl hydrocarbon receptor
JP2020503043A (ja) * 2016-12-30 2020-01-30 セルラリティ インコーポレイテッド 遺伝子改変されたナチュラルキラー細胞
KR102660336B1 (ko) 2017-03-27 2024-04-26 내셔널 유니버시티 오브 싱가포르 절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
MX2019011570A (es) 2017-03-27 2019-11-18 Nat Univ Singapore Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
WO2019036657A1 (en) * 2017-08-17 2019-02-21 Kyn Therapeutics AHR INHIBITORS AND USES THEREOF
WO2019059713A2 (ko) * 2017-09-21 2019-03-28 한국생명공학연구원 자연살해세포의 제조방법 및 그의 용도
KR102167548B1 (ko) 2017-09-21 2020-10-19 한국생명공학연구원 자연살해세포의 제조방법 및 그의 용도
AU2019219454A1 (en) 2018-02-09 2020-08-27 National University Of Singapore Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
US12011460B2 (en) 2018-02-20 2024-06-18 Universite De Montreal Expansion of NK and DC cells in vivo mediating immune response
CN112055717B (zh) 2018-04-02 2024-04-26 新加坡国立大学 用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
JP2021525066A (ja) 2018-05-30 2021-09-24 グリコステム セラピューティクス ベスローテン フェンノートシャップ Car nk細胞
EP3844186A4 (en) 2018-08-29 2022-08-17 National University of Singapore METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
CA3112951A1 (en) * 2018-10-01 2020-04-09 Universiteit Gent Accelerated human hematopoietic stem cell differentiation towards mature natural killer cells with enhanced antibody-dependent cytotoxic activity
CN109294985B (zh) * 2018-10-25 2022-02-18 江苏普瑞康生物医药科技有限公司 一种用于nk细胞体外扩增的培养基体系及nk细胞体外扩增的方法
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
CN113454207A (zh) * 2018-11-30 2021-09-28 细胞结构公司 用新型芳香族化合物扩增自然杀伤细胞和ilc3细胞
WO2020124256A1 (en) * 2018-12-21 2020-06-25 Stemcell Technologies Canada Inc. Media and methods for differentiating natural killer cells
CA3125503A1 (en) * 2019-01-18 2020-07-23 Acepodia Biotechnologies Ltd. A novel cd16+ natural killer cell and a method of culturing cd16+ natural killer cell
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
WO2020197318A1 (ko) * 2019-03-28 2020-10-01 한국생명공학연구원 Car 유전자가 도입된 nk 세포의 제조방법 및 그의 용도
CN110079529A (zh) * 2019-04-28 2019-08-02 成都美杰赛尔生物科技有限公司 用于靶向敲除人NKG2A/KLRC1基因的sgRNA、表达载体、试剂盒及其用途
WO2020252464A1 (en) * 2019-06-14 2020-12-17 Celularity Inc. Populations of natural killer cells for treating cancers
CN113652393B (zh) * 2020-05-12 2023-08-15 内蒙古大学 一种提高牛胚胎干细胞多能性的方法
US11591381B2 (en) 2020-11-30 2023-02-28 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
CN113046314B (zh) * 2021-03-30 2022-11-25 中国科学技术大学 一种人脐血或骨髓造血干细胞体外诱导扩增蜕膜样自然杀伤细胞的方法
CN113337466B (zh) * 2021-07-13 2023-03-24 杭州原生生物科技有限公司 一种无血清nk分化培养基及其制备方法
CN115381959A (zh) * 2022-09-30 2022-11-25 上海纳米技术及应用国家工程研究中心有限公司 一种治疗肝癌的联合用药

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MX342995B (es) * 2010-07-13 2016-10-21 Anthrogenesis Corp Métodos de generar células asesinas naturales.
PT2807165T (pt) * 2012-01-27 2019-07-12 Univ Montreal Derivados de pirimido[4,5-b]indole e sua utilização na expansão de células estaminais hematopoiéticas
DK2812011T3 (da) * 2012-02-08 2020-02-24 Glycostem Therapeutics B V Differentiering ex vivo af nk-celler fra cd34+ hæmatopoietiske celler
US9175266B2 (en) * 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
CN114134113A (zh) * 2012-08-13 2022-03-04 人类起源公司 自然杀伤细胞及其用途

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