JP2023126852A5 - - Google Patents
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- JP2023126852A5 JP2023126852A5 JP2023105962A JP2023105962A JP2023126852A5 JP 2023126852 A5 JP2023126852 A5 JP 2023126852A5 JP 2023105962 A JP2023105962 A JP 2023105962A JP 2023105962 A JP2023105962 A JP 2023105962A JP 2023126852 A5 JP2023126852 A5 JP 2023126852A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- cells
- composition according
- isoform
- surface protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16196858 | 2016-11-02 | ||
| EP16196860.7 | 2016-11-02 | ||
| EP16196860 | 2016-11-02 | ||
| EP16196858.1 | 2016-11-02 | ||
| EPPCT/EP2017/059799 | 2017-04-25 | ||
| PCT/EP2017/059799 WO2017186718A1 (en) | 2016-04-25 | 2017-04-25 | Allele editing and applications thereof |
| EP17197820 | 2017-10-23 | ||
| EP17197820.8 | 2017-10-23 | ||
| PCT/EP2017/077826 WO2018083071A1 (en) | 2016-11-02 | 2017-10-30 | Immunologically discernible cell surface variants for use in cell therapy |
| JP2019521099A JP7305539B2 (ja) | 2016-11-02 | 2017-10-30 | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521099A Division JP7305539B2 (ja) | 2016-11-02 | 2017-10-30 | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023126852A JP2023126852A (ja) | 2023-09-12 |
| JP2023126852A5 true JP2023126852A5 (https=) | 2023-12-04 |
| JP7676472B2 JP7676472B2 (ja) | 2025-05-14 |
Family
ID=62075802
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521099A Active JP7305539B2 (ja) | 2016-11-02 | 2017-10-30 | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 |
| JP2023105962A Active JP7676472B2 (ja) | 2016-11-02 | 2023-06-28 | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521099A Active JP7305539B2 (ja) | 2016-11-02 | 2017-10-30 | 細胞療法に使用するための、免疫学的に識別できる細胞表面変異体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20190365806A1 (https=) |
| EP (2) | EP4360639A3 (https=) |
| JP (2) | JP7305539B2 (https=) |
| KR (2) | KR20190072639A (https=) |
| CN (1) | CN110191948A (https=) |
| AU (1) | AU2017355218B2 (https=) |
| BR (1) | BR112019008975A2 (https=) |
| CA (1) | CA3041582A1 (https=) |
| DK (1) | DK3535392T3 (https=) |
| ES (1) | ES2977969T3 (https=) |
| FI (1) | FI3535392T3 (https=) |
| HR (1) | HRP20240842T1 (https=) |
| HU (1) | HUE067685T2 (https=) |
| IL (1) | IL266362B2 (https=) |
| LT (1) | LT3535392T (https=) |
| MX (1) | MX2019005125A (https=) |
| PL (1) | PL3535392T3 (https=) |
| SG (1) | SG11201903454VA (https=) |
| SI (1) | SI3535392T1 (https=) |
| WO (1) | WO2018083071A1 (https=) |
| ZA (1) | ZA201902426B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS61907B1 (sr) | 2015-04-06 | 2021-06-30 | Subdomain Llc | Polipeptidi koji sadrže de novo vezujući domen i njihova primena |
| AU2016337525B2 (en) | 2015-10-16 | 2022-01-20 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for inhibition of lineage specific antigens |
| US11499168B2 (en) | 2016-04-25 | 2022-11-15 | Universitat Basel | Allele editing and applications thereof |
| CA3053534A1 (en) * | 2017-02-17 | 2018-08-23 | Purdue Research Foundation | Targeted ligand-payload based drug delivery for cell therapy |
| RU2019130504A (ru) | 2017-02-28 | 2021-03-30 | Вор Байофарма, Инк. | Композиции и способы ингибирования линиеспецифических белков |
| KR20250070609A (ko) | 2017-11-14 | 2025-05-20 | 아르셀엑스, 인크. | 다기능성 면역 세포 요법 |
| US11464803B2 (en) | 2017-11-14 | 2022-10-11 | Arcellx, Inc. | D-domain containing polypeptides and uses thereof |
| RS67119B1 (sr) | 2017-11-14 | 2025-09-30 | Arcellx Inc | Polipeptidi koji obuhvataju d domen i njihove upotrebe |
| AU2019265019B2 (en) | 2018-05-11 | 2025-11-06 | Beam Therapeutics Inc. | Methods of substituting pathogenic amino acids using programmable base editor systems |
| KR20210045360A (ko) | 2018-05-16 | 2021-04-26 | 신테고 코포레이션 | 가이드 rna 설계 및 사용을 위한 방법 및 시스템 |
| US12281151B2 (en) | 2018-06-29 | 2025-04-22 | City Of Hope | CD6 targeted chimeric antigen receptors for treatment of certain autoimmune disorders |
| WO2020043750A1 (en) * | 2018-08-28 | 2020-03-05 | Roche Innovation Center Copenhagen A/S | Neoantigen engineering using splice modulating compounds |
| CA3110837A1 (en) | 2018-08-28 | 2020-03-05 | Vor Biopharma Inc. | Genetically engineered hematopoietic stem cells and uses thereof |
| EP3908372A1 (en) * | 2019-01-13 | 2021-11-17 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Antibodies specific to human nectin-2 |
| KR102689877B1 (ko) * | 2019-11-28 | 2024-08-01 | 주식회사 센트릭스바이오 | CD300c 항원 또는 그의 수용체에 특이적으로 결합하는 키메라 항원 수용체 |
| WO2021138454A1 (en) * | 2019-12-30 | 2021-07-08 | City Of Hope | Methods of making and using regulatory t cells and effector t cells having chimeric antigen receptors targeted to cd6, cd19, and/or an il-13r for treatment of autoimmune disorders and cancers |
| KR102347797B1 (ko) * | 2020-03-03 | 2022-01-07 | 한국과학기술원 | 대식세포 세포 표면 항원 및 이의 다양한 용도 |
| EP4126243A4 (en) * | 2020-03-27 | 2024-06-12 | The Trustees of Indiana University | Immunotherapeutic targets in multiple myeloma and methods for their identification |
| JP2024502820A (ja) * | 2020-12-31 | 2024-01-23 | ブイオーアール バイオファーマ インコーポレーテッド | Ｃｄ３４遺伝子改変のための組成物及び方法 |
| WO2022150831A1 (en) * | 2021-01-07 | 2022-07-14 | Innovative Cellular Therapeutics Holdings, Ltd. | Car cells and polyspecific binding molecules for treating solid tumor |
| CN112852875B (zh) * | 2021-02-26 | 2022-10-21 | 福建省立医院 | 示踪肿瘤T淋巴细胞浸润的CD3e转基因小鼠模型的构建方法 |
| CN113109575A (zh) * | 2021-04-16 | 2021-07-13 | 浙江普罗亭健康科技有限公司 | 一种用于监测人体免疫状态的40抗体试剂盒及应用 |
| CN113125733A (zh) * | 2021-04-16 | 2021-07-16 | 浙江普罗亭健康科技有限公司 | 一种用于监测人体免疫状态的42抗体试剂盒及应用 |
| CN113125755A (zh) * | 2021-04-16 | 2021-07-16 | 浙江普罗亭健康科技有限公司 | 一种用于监测人体免疫状态的9抗体试剂盒及应用 |
| CN113125718A (zh) * | 2021-04-16 | 2021-07-16 | 浙江普罗亭健康科技有限公司 | 一种用于监测人体免疫状态的45抗体试剂盒及应用 |
| CN113125754A (zh) * | 2021-04-16 | 2021-07-16 | 浙江普罗亭健康科技有限公司 | 一种用于监测人体免疫状态的23抗体试剂盒及应用 |
| AU2021447099A1 (en) * | 2021-05-27 | 2023-02-16 | Cas Lamvac (Guangzhou) Biomedical Technology Co., Ltd. | Method and kit for analyzing phenotype and function of CD303 |
| WO2023283585A2 (en) | 2021-07-06 | 2023-01-12 | Vor Biopharma Inc. | Inhibitor oligonucleotides and methods of use thereof |
| AU2022324093A1 (en) | 2021-08-02 | 2024-02-08 | Vor Biopharma Inc. | Compositions and methods for gene modification |
| JP2024530465A (ja) | 2021-08-06 | 2024-08-21 | ウニバズィテート バーゼル | 細胞療法に使用するための識別可能な細胞表面タンパク質変異体 |
| EP4448573A1 (en) | 2021-12-16 | 2024-10-23 | Universität Basel | Discernible cell surface protein variants of cd117 for use in cell therapy |
| AU2022422572A1 (en) | 2021-12-23 | 2024-06-06 | Cimeio Therapeutics Ag | Discernible cell surface protein variants of cd45 for use in cell therapy |
| CN114292830B (zh) * | 2021-12-31 | 2024-05-03 | 复旦大学 | 蛋白SaCas9的抗原表位及其在基因编辑中的应用 |
| WO2024015925A2 (en) * | 2022-07-13 | 2024-01-18 | Vor Biopharma Inc. | Compositions and methods for artificial protospacer adjacent motif (pam) generation |
| WO2024073751A1 (en) | 2022-09-29 | 2024-04-04 | Vor Biopharma Inc. | Methods and compositions for gene modification and enrichment |
| EP4611807A1 (en) * | 2022-11-04 | 2025-09-10 | The Board of Trustees of the Leland Stanford Junior University | Rebalancing the immune system through depletion of myeloid-biased hematopoietic stem cells |
| CN117912552B (zh) * | 2023-01-07 | 2025-03-28 | 杭州链康医学检验实验室有限公司 | 一种pdx模型单细胞转录组数据的分析方法、设备和介质 |
| EP4688850A1 (en) | 2023-04-03 | 2026-02-11 | Universität Basel | Discernible cell surface protein variants of cd33 for use in cell therapy |
| WO2025031965A1 (en) | 2023-08-04 | 2025-02-13 | Cimeio Therapeutics Ag | Discernible cell surface protein variants of cd52 for use in cell therapy |
| WO2025132801A1 (en) | 2023-12-19 | 2025-06-26 | Cimeio Therapeutics Ag | Discernible protein variants of bcl-2 for use in cell therapy |
| CN120738344A (zh) * | 2025-08-26 | 2025-10-03 | 北京康美天鸿生物科技有限公司 | 检测地中海贫血基因突变的引物组及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002070738A2 (en) * | 2001-03-07 | 2002-09-12 | Andre Schuh | Diagnosis and treatment of blood disorders |
| EP1674479A1 (en) * | 2004-12-22 | 2006-06-28 | Memorial Sloan-Kettering Cancer Center | Modulation of Fc Gamma receptors for optimizing immunotherapy |
| WO2007087453A2 (en) * | 2006-01-27 | 2007-08-02 | Cellerant Therapeutics, Inc. | Compositions and methods for treating haematological proliferative disorders |
| WO2008067115A2 (en) * | 2006-11-03 | 2008-06-05 | The Board Of Trustees Of The Leland Stanford Junior University | Selective immunodepletion of endogenous stem cell niche for engraftment |
| WO2009023816A1 (en) * | 2007-08-15 | 2009-02-19 | Emory University | Methods of making monoclonal antibodies using fusion- peptide epitope adoptive transfer (f-peat) technology |
| CN102271711B (zh) * | 2008-12-12 | 2014-06-18 | 国立大学法人东京大学 | 每种维持移植物抗肿瘤效应的免疫重建促进剂或感染预防剂 |
| PL3360964T3 (pl) | 2012-12-06 | 2020-03-31 | Sigma-Aldrich Co. Llc | Modyfikacja i regulacja genomu oparta na crispr |
| EP3666795A1 (en) * | 2013-03-12 | 2020-06-17 | Molecular Templates, Inc. | Cytotoxic proteins comprising cell-targeting binding regions and shiga toxin a subunit regions for selective killing of specific cell types |
| ES2791598T3 (es) | 2013-06-05 | 2020-11-05 | Bellicum Pharmaceuticals Inc | Métodos para inducir apoptosis parcial utilizando polipéptidos de caspasa |
| CA2914213A1 (en) * | 2013-06-17 | 2014-12-24 | Alain Moreau | A method of increasing gipcr signalization in the cells of a scoliotic subject |
| WO2016014837A1 (en) * | 2014-07-25 | 2016-01-28 | Sangamo Biosciences, Inc. | Gene editing for hiv gene therapy |
| US10201606B2 (en) * | 2014-11-26 | 2019-02-12 | Miltenyi Biotec Gmbh | Combination immunotherapy of antigen-recognizing receptors and hematopoietic cells for the treatment of diseases |
| HK1256681A1 (zh) * | 2015-04-06 | 2019-10-04 | President And Fellows Of Harvard College | 用於非清髓性预处理的组合物和方法 |
| WO2017079400A1 (en) | 2015-11-04 | 2017-05-11 | The Trustees Of The University Of Pennsylvania | Methods and compositions for gene editing in hematopoietic stem cells |
| JP2019508037A (ja) * | 2016-02-16 | 2019-03-28 | イェール ユニバーシティーＹａｌｅ Ｕｎｉｖｅｒｓｉｔ | 標的化遺伝子編集を増強するための組成物およびその使用方法 |
| JP2019508051A (ja) * | 2016-03-14 | 2019-03-28 | エディタス・メディシン、インコーポレイテッド | β異常ヘモグロビン症を治療するためのＣＲＩＳＰＲ／ＣＡＳ関連方法および組成物 |
| US11499168B2 (en) * | 2016-04-25 | 2022-11-15 | Universitat Basel | Allele editing and applications thereof |
-
2017
- 2017-10-30 LT LTEPPCT/EP2017/077826T patent/LT3535392T/lt unknown
- 2017-10-30 EP EP24155910.3A patent/EP4360639A3/en active Pending
- 2017-10-30 US US16/346,185 patent/US20190365806A1/en active Pending
- 2017-10-30 KR KR1020197015826A patent/KR20190072639A/ko not_active Ceased
- 2017-10-30 SG SG11201903454VA patent/SG11201903454VA/en unknown
- 2017-10-30 IL IL266362A patent/IL266362B2/en unknown
- 2017-10-30 MX MX2019005125A patent/MX2019005125A/es unknown
- 2017-10-30 KR KR1020247009264A patent/KR20240043810A/ko active Pending
- 2017-10-30 PL PL17797585.1T patent/PL3535392T3/pl unknown
- 2017-10-30 JP JP2019521099A patent/JP7305539B2/ja active Active
- 2017-10-30 ES ES17797585T patent/ES2977969T3/es active Active
- 2017-10-30 EP EP17797585.1A patent/EP3535392B1/en active Active
- 2017-10-30 CA CA3041582A patent/CA3041582A1/en active Pending
- 2017-10-30 WO PCT/EP2017/077826 patent/WO2018083071A1/en not_active Ceased
- 2017-10-30 BR BR112019008975-6A patent/BR112019008975A2/pt active Search and Examination
- 2017-10-30 CN CN201780067985.1A patent/CN110191948A/zh active Pending
- 2017-10-30 FI FIEP17797585.1T patent/FI3535392T3/fi active
- 2017-10-30 AU AU2017355218A patent/AU2017355218B2/en active Active
- 2017-10-30 HR HRP20240842TT patent/HRP20240842T1/hr unknown
- 2017-10-30 DK DK17797585.1T patent/DK3535392T3/da active
- 2017-10-30 HU HUE17797585A patent/HUE067685T2/hu unknown
- 2017-10-30 SI SI201731518T patent/SI3535392T1/sl unknown
-
2019
- 2019-04-16 ZA ZA2019/02426A patent/ZA201902426B/en unknown
-
2023
- 2023-06-28 JP JP2023105962A patent/JP7676472B2/ja active Active
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