JP2023537534A5 - - Google Patents

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Publication number
JP2023537534A5
JP2023537534A5 JP2023510439A JP2023510439A JP2023537534A5 JP 2023537534 A5 JP2023537534 A5 JP 2023537534A5 JP 2023510439 A JP2023510439 A JP 2023510439A JP 2023510439 A JP2023510439 A JP 2023510439A JP 2023537534 A5 JP2023537534 A5 JP 2023537534A5
Authority
JP
Japan
Prior art keywords
epitope
fragment
antibody
polyspecific
polyspecific antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023510439A
Other languages
English (en)
Japanese (ja)
Other versions
JP7847579B2 (ja
JP2023537534A (ja
Filing date
Publication date
Priority claimed from PCT/GB2020/051959 external-priority patent/WO2021032963A1/en
Priority claimed from GBGB2102224.9A external-priority patent/GB202102224D0/en
Priority claimed from GBGB2102222.3A external-priority patent/GB202102222D0/en
Application filed filed Critical
Priority claimed from PCT/IB2021/057509 external-priority patent/WO2022034562A1/en
Publication of JP2023537534A publication Critical patent/JP2023537534A/ja
Publication of JP2023537534A5 publication Critical patent/JP2023537534A5/ja
Application granted granted Critical
Publication of JP7847579B2 publication Critical patent/JP7847579B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023510439A 2020-08-14 2021-08-14 多特異性抗tcrデルタ可変1抗体 Active JP7847579B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/GB2020/051959 WO2021032963A1 (en) 2019-08-16 2020-08-14 Therapeutic uses of anti-tcr delta variable 1 antibodies
GBPCT/GB2020/051959 2020-08-14
GBGB2102224.9A GB202102224D0 (en) 2021-02-17 2021-02-17 Anti-TRC delta variable 1 antibodies
GB2102222.3 2021-02-17
GB2102224.9 2021-02-17
GBGB2102222.3A GB202102222D0 (en) 2021-02-17 2021-02-17 Multispecific anti-TCR delta variable 1 antibodies
PCT/IB2021/057509 WO2022034562A1 (en) 2020-08-14 2021-08-14 Multispecific anti-tcr delta variable 1 antibodies

Publications (3)

Publication Number Publication Date
JP2023537534A JP2023537534A (ja) 2023-09-01
JP2023537534A5 true JP2023537534A5 (https=) 2024-08-21
JP7847579B2 JP7847579B2 (ja) 2026-04-17

Family

ID=80247426

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023510439A Active JP7847579B2 (ja) 2020-08-14 2021-08-14 多特異性抗tcrデルタ可変1抗体

Country Status (18)

Country Link
EP (7) EP4265642B1 (https=)
JP (1) JP7847579B2 (https=)
KR (1) KR20230083267A (https=)
CN (1) CN116209456A (https=)
AU (1) AU2021323512A1 (https=)
BR (1) BR112023002741A2 (https=)
CA (1) CA3188682A1 (https=)
CO (1) CO2023003009A2 (https=)
DK (2) DK4010082T4 (https=)
ES (2) ES2943063T3 (https=)
FI (2) FI4010082T4 (https=)
IL (1) IL300517A (https=)
LT (2) LT4010082T (https=)
MX (1) MX2023001728A (https=)
PL (2) PL4269444T3 (https=)
PT (2) PT4010082T (https=)
SI (2) SI4010082T1 (https=)
WO (1) WO2022034562A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL4269444T3 (pl) 2020-08-14 2025-01-13 GammaDelta Therapeutics Limited Wieloswoiste przeciwciała anty-tcr zmienne delta 1
WO2023250485A1 (en) * 2022-06-23 2023-12-28 LAVA Therapeutics N.V. Assay for t cell dependent multispecific compounds
WO2024193459A1 (en) * 2023-03-17 2024-09-26 Nanjing Legend Biotech Co., Ltd. METHODS OF CULTURING Vδ1 T CELLS
WO2025147597A1 (en) * 2024-01-05 2025-07-10 Eugit Therapeutics, Inc. Targeting payloads
WO2025191133A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Il-21 muteins, fusion proteins comprising the same and uses thereof
WO2025191136A1 (en) 2024-03-15 2025-09-18 Avidicure Ip B.V. Muteins of 4-1bb ligand extracellular domain, fusion proteins comprising the same and uses thereof

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2546268A1 (en) 2011-07-13 2013-01-16 F-Star Biotechnologische Forschungs - und Entwicklungsges. M.B.H. Internalising immunoglobulin
WO2015063069A1 (en) * 2013-10-28 2015-05-07 Benjamin Felder Chimeric antigen receptors with antigen binding domains derived from gamma delta t cell receptors
GB201506423D0 (en) * 2015-04-15 2015-05-27 Tc Biopharm Ltd Gamma delta T cells and uses thereof
AU2016274633B2 (en) 2015-06-09 2022-04-21 Gammadelta Therapeutics Ltd Methods for the production of TCR gamma delta+ T cells
EP3344658B1 (en) 2015-09-02 2022-05-11 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Antibodies specific to human t-cell immunoglobulin and itim domain (tigit)
WO2017072367A1 (en) 2015-10-30 2017-05-04 Cancer Research Technology Limited EXPANSION OF NON-HAEMATOPOIETIC TISSUE-RESIDENT γδ T CELLS AND USES OF THESE CELLS
US11299708B2 (en) 2016-05-12 2022-04-12 Adicet Bio, Inc. Methods for selective expansion of γδ T-cell populations and compositions thereof
GB201612520D0 (en) 2016-07-19 2016-08-31 F-Star Beta Ltd Binding molecules
US20180028566A1 (en) 2016-07-29 2018-02-01 New York University Gamma delta t cells as a target for treatment of solid tumors
US10546518B2 (en) 2017-05-15 2020-01-28 Google Llc Near-eye display with extended effective eyebox via eye tracking
EP3645050A4 (en) 2017-06-25 2021-08-11 Systimmune, Inc. Multi-specific antibodies and methods of making and using thereof
EP3743081A4 (en) 2018-01-23 2021-12-01 New York University SPECIFIC ANTIBODIES OF THE DELTA 1 CHAIN OF THE T-LYMPHOCYTE RECEPTOR
AU2019344300A1 (en) * 2018-09-19 2021-04-22 LAVA Therapeutics N.V. Dual acting CD1D immunoglobulin
GB201818243D0 (en) 2018-11-08 2018-12-26 Gammadelta Therapeutics Ltd Methods for isolating and expanding cells
US12084500B2 (en) * 2019-01-23 2024-09-10 New York University Antibodies specific to delta 1 chain of T cell receptor
CN113993893A (zh) * 2019-02-01 2022-01-28 拉法医疗有限公司 新cd40结合抗体
CA3136251A1 (en) 2019-04-08 2020-10-15 Memorial Sloan Kettering Cancer Center Cd19 antibodies and methods of using the same
JP2022545196A (ja) * 2019-08-16 2022-10-26 ガンマデルタ セラピューティクス リミテッド 抗tcrデルタ可変1抗体の治療的使用
JP7764364B2 (ja) 2019-08-16 2025-11-05 ガンマデルタ セラピューティクス リミティッド エクスビボγδ T細胞集団
PL4269444T3 (pl) 2020-08-14 2025-01-13 GammaDelta Therapeutics Limited Wieloswoiste przeciwciała anty-tcr zmienne delta 1
AU2022224391A1 (en) 2021-02-17 2023-08-24 Gammadelta Therapeutics Ltd Anti-tcr delta variable 1 antibodies

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