JP2023078418A5 - - Google Patents
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- Publication number
- JP2023078418A5 JP2023078418A5 JP2023049452A JP2023049452A JP2023078418A5 JP 2023078418 A5 JP2023078418 A5 JP 2023078418A5 JP 2023049452 A JP2023049452 A JP 2023049452A JP 2023049452 A JP2023049452 A JP 2023049452A JP 2023078418 A5 JP2023078418 A5 JP 2023078418A5
- Authority
- JP
- Japan
- Prior art keywords
- tautomer
- trifluoromethyl
- alkyl
- compound
- pyrazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962939821P | 2019-11-25 | 2019-11-25 | |
| US62/939,821 | 2019-11-25 | ||
| PCT/US2020/062020 WO2021108408A1 (en) | 2019-11-25 | 2020-11-24 | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use |
| JP2022529556A JP7254246B2 (ja) | 2019-11-25 | 2020-11-24 | デルタ－５デサチュラーゼ阻害剤としての複素環式化合物及び使用方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022529556A Division JP7254246B2 (ja) | 2019-11-25 | 2020-11-24 | デルタ－５デサチュラーゼ阻害剤としての複素環式化合物及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023078418A JP2023078418A (ja) | 2023-06-06 |
| JP2023078418A5 true JP2023078418A5 (enExample) | 2023-11-20 |
| JP7698676B2 JP7698676B2 (ja) | 2025-06-25 |
Family
ID=73855555
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022529556A Active JP7254246B2 (ja) | 2019-11-25 | 2020-11-24 | デルタ－５デサチュラーゼ阻害剤としての複素環式化合物及び使用方法 |
| JP2023049452A Active JP7698676B2 (ja) | 2019-11-25 | 2023-03-27 | デルタ－５デサチュラーゼ阻害剤としての複素環式化合物及び使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022529556A Active JP7254246B2 (ja) | 2019-11-25 | 2020-11-24 | デルタ－５デサチュラーゼ阻害剤としての複素環式化合物及び使用方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US11512097B2 (enExample) |
| EP (1) | EP4065223A1 (enExample) |
| JP (2) | JP7254246B2 (enExample) |
| KR (2) | KR20230154292A (enExample) |
| CN (2) | CN114728167B (enExample) |
| AR (1) | AR120556A1 (enExample) |
| AU (1) | AU2020392087B2 (enExample) |
| BR (1) | BR112022010054A2 (enExample) |
| CA (1) | CA3162281A1 (enExample) |
| CL (2) | CL2022001357A1 (enExample) |
| CO (1) | CO2022008690A2 (enExample) |
| CR (1) | CR20220308A (enExample) |
| IL (1) | IL293191B2 (enExample) |
| JO (1) | JOP20220125A1 (enExample) |
| MX (1) | MX2022006281A (enExample) |
| PE (1) | PE20231097A1 (enExample) |
| PH (1) | PH12022551282A1 (enExample) |
| SA (1) | SA522432710B1 (enExample) |
| TW (2) | TWI815061B (enExample) |
| UY (1) | UY38971A (enExample) |
| WO (1) | WO2021108408A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11220510B2 (en) * | 2018-04-09 | 2022-01-11 | Incyte Corporation | Pyrrole tricyclic compounds as A2A / A2B inhibitors |
| PH12022551282A1 (en) * | 2019-11-25 | 2023-11-29 | Amgen Inc | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use |
| CN115557903A (zh) * | 2022-09-27 | 2023-01-03 | 山东潍坊润丰化工股份有限公司 | 一种特草定的制备方法 |
| TW202434254A (zh) | 2022-11-23 | 2024-09-01 | 美商安進公司 | 選擇用於fads1調節劑治療的患者之方法 |
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| DE3130633A1 (de) | 1981-08-01 | 1983-02-17 | Basf Ag, 6700 Ludwigshafen | 7-amino-azolo(1,5-a)pyrimidine und diese enthaltende fungizide |
| JP2641443B2 (ja) | 1986-04-07 | 1997-08-13 | クミアイ化学工業株式会社 | ５Ｈ−１，３，４−チアジアゾロ〔３，２−ａ〕ピリミジン−５−オン誘導体及びこれを有効成分とする農園芸用殺菌剤 |
| US6096753A (en) | 1996-12-05 | 2000-08-01 | Amgen Inc. | Substituted pyrimidinone and pyridone compounds and methods of use |
| CN1328277C (zh) | 1996-12-05 | 2007-07-25 | 安姆根有限公司 | 取代的嘧啶酮和吡啶酮化合物和它们的应用 |
| CA2386942A1 (en) | 1999-10-15 | 2001-04-26 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| US6537998B1 (en) * | 1999-10-15 | 2003-03-25 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| AU2003238157A1 (en) | 2002-06-18 | 2003-12-31 | Sankyo Company, Limited | Fused-ring pyrimidin-4(3h)-one derivatives, processes for the preparation and uses thereof |
| JP2004107228A (ja) | 2002-09-17 | 2004-04-08 | Nippon Nohyaku Co Ltd | 双環性ピリミジノン誘導体及びこれを有効成分とする除草剤 |
| PE20051089A1 (es) | 2004-01-22 | 2006-01-25 | Novartis Ag | Derivados de pirazolo [1,5-a] pirimidin-7-il-amina como inhibidores de quinasa de proteina |
| US20050222171A1 (en) | 2004-01-22 | 2005-10-06 | Guido Bold | Organic compounds |
| WO2006067401A1 (en) | 2004-12-24 | 2006-06-29 | Astrazeneca Ab | Heterocyclic compounds as ccr2b antagonists |
| WO2007002701A2 (en) | 2005-06-27 | 2007-01-04 | Amgen Inc. | Anti-inflammatory aryl nitrile compounds |
| WO2007027012A1 (en) | 2005-07-18 | 2007-03-08 | Samsung Electronics Co., Ltd. | Video coding method and apparatus for reducing mismatch between encoder and decoder |
| AU2006274075A1 (en) | 2005-07-27 | 2007-02-01 | Basf Se | Fungicide 6-phenyl-triazolopyrimidinyl amines |
| JP2009502864A (ja) | 2005-07-27 | 2009-01-29 | ビーエーエスエフ ソシエタス・ヨーロピア | 殺菌性の５−メチル−６−フェニルトリアゾロピリミジニルアミン |
| BRPI0614104A2 (pt) | 2005-07-27 | 2016-11-22 | Basf Ag | compostos, processo para preparar compostos, agente fungicida, semente, e, processo para combater fungos nocivos fitopatogênicos |
| BRPI0616985B1 (pt) | 2005-10-06 | 2021-10-26 | Merck Sharp & Dohme Corp. | Composto de pirazolo[1,5-a]pirimidina, e, uso de um composto |
| KR20090073120A (ko) | 2006-09-28 | 2009-07-02 | 노파르티스 아게 | 피라졸로[1,5-ａ]피리미딘 유도체 및 이들의 치료 용도 |
| JP2010505881A (ja) | 2006-10-05 | 2010-02-25 | ギリアード・パロ・アルト・インコーポレイテッド | ステアロイルＣｏＡデサチュラーゼインヒビターとして使用するための二環式窒素含有複素環式化合物 |
| US8173661B2 (en) | 2006-11-08 | 2012-05-08 | The Rockefeller University | Alpha-IIB-beta-3 inhibitors and uses thereof |
| WO2008089307A2 (en) | 2007-01-18 | 2008-07-24 | Lexicon Pharmaceuticals, Inc. | Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer |
| US20080200458A1 (en) | 2007-01-18 | 2008-08-21 | Joseph Barbosa | Methods and compositions for the treatment of body composition disorders |
| BRPI0806347A2 (pt) | 2007-01-19 | 2011-09-06 | Basf Se | misturas fungicidas, agente fungicida, método para combater fungos nocivos fitopagênicos, semente, e, processo para preparar um agente |
| WO2008092836A2 (en) | 2007-01-30 | 2008-08-07 | Basf Se | Method for improving plant health |
| BRPI0809045A2 (pt) | 2007-03-23 | 2014-09-02 | Basf Se | Combinações de substância ativa, uso de combinações de substância ativa, métodos para combater fungos fitopatogênicos indesejáveis, para preparar agentes pesticidas, e para tratar sementes, e, produto de revestimento de semente |
| CA2709784A1 (en) | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| JP2011516496A (ja) | 2008-04-04 | 2011-05-26 | ギリアード サイエンシーズ， インコーポレイテッド | ステアロイル−ＣｏＡデサチュラーゼの阻害剤として使用するためのピロロトリアジノン誘導体 |
| US8119647B2 (en) * | 2008-04-23 | 2012-02-21 | Glenmark Pharmaceuticals S.A. | Fused pyrimidineone compounds as TRPV3 modulators |
| US20100099561A1 (en) | 2008-10-15 | 2010-04-22 | E.I. Du Pont De Nemours And Company | Heterobicyclic alkylthio-bridged isoxazolines |
| US20100190747A1 (en) | 2009-01-27 | 2010-07-29 | Hideo Suzuki | Fused ring compound and use thereof |
| HRP20140754T2 (hr) | 2009-06-29 | 2015-07-17 | Incyte Corporation | Pirimidinoni kao inhibitori pi3k |
| WO2011114148A1 (en) * | 2010-03-17 | 2011-09-22 | Astrazeneca Ab | 4h- [1, 2, 4] triazolo [5, 1 -b] pyrimidin-7 -one derivatives as ccr2b receptor antagonists |
| JPWO2012011592A1 (ja) | 2010-07-23 | 2013-09-09 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| WO2012125629A1 (en) | 2011-03-14 | 2012-09-20 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors |
| US8952012B2 (en) | 2012-05-24 | 2015-02-10 | Colorado State University Research Foundation | Inhibition of delta-6 desaturase for the treatment of cardiometabolic disease |
| US20140275092A1 (en) | 2013-03-13 | 2014-09-18 | Constellation Pharmaceuticals, Inc. | Pyrazolo compounds and uses thereof |
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| WO2015064714A1 (ja) | 2013-10-31 | 2015-05-07 | 国立大学法人東京大学 | オートタキシン阻害活性を有する１－置換イミダゾピリミジノン誘導体 |
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| KR102458990B1 (ko) | 2014-04-23 | 2022-10-25 | 미쓰비시 타나베 파마 코퍼레이션 | 신규한 바이시클릭 또는 트리시클릭 헤테로시클릭 화합물 |
| WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
| JP6791717B2 (ja) | 2015-10-22 | 2020-11-25 | 田辺三菱製薬株式会社 | 医薬組成物 |
| JP2017091808A (ja) | 2015-11-10 | 2017-05-25 | 株式会社フジクラ | 酸化物超電導線材の製造方法及び超電導コイルの製造方法 |
| EP3394032A4 (en) | 2015-12-21 | 2019-09-18 | The University of Chicago | COMPOUNDS AND METHODS OF TREATMENT, DETECTION AND IDENTIFICATION OF COMPOUNDS FOR THE TREATMENT OF PARASITIC ILLNESSES BY APICOMPLEXA |
| MX390277B (es) | 2016-08-31 | 2025-03-20 | Servier Lab | Inhibidores de procesos metabolicos celulares. |
| WO2018039972A1 (en) * | 2016-08-31 | 2018-03-08 | Agios Pharmaceuticals, Inc. | Inhibitors of cellular metabolic processes |
| CN106749271B (zh) * | 2016-12-07 | 2019-04-05 | 青岛科技大学 | 一类[1,2,4]-三氮唑并[1,5-a]嘧啶酮类杂环化合物、其制备方法及其用途 |
| SG11201910197SA (en) | 2017-05-15 | 2019-11-28 | Dana Farber Cancer Inst Inc | Compounds for treating dengue virus infection and other viral infections |
| WO2018229683A1 (en) | 2017-06-15 | 2018-12-20 | Novartis Ag | 5,6-fused-bicyclic compounds and compositions for the treatment of parasitic diseases |
| KR20200032751A (ko) | 2017-09-15 | 2020-03-26 | 아두로 바이오테크, 인코포레이티드 | 피라졸로피리미디논 화합물 및 그의 용도 |
| PH12022551282A1 (en) | 2019-11-25 | 2023-11-29 | Amgen Inc | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use |
-
2020
- 2020-11-24 PH PH1/2022/551282A patent/PH12022551282A1/en unknown
- 2020-11-24 WO PCT/US2020/062020 patent/WO2021108408A1/en not_active Ceased
- 2020-11-24 BR BR112022010054A patent/BR112022010054A2/pt unknown
- 2020-11-24 PE PE2022000849A patent/PE20231097A1/es unknown
- 2020-11-24 JP JP2022529556A patent/JP7254246B2/ja active Active
- 2020-11-24 CN CN202080081465.8A patent/CN114728167B/zh active Active
- 2020-11-24 US US17/103,389 patent/US11512097B2/en active Active
- 2020-11-24 MX MX2022006281A patent/MX2022006281A/es unknown
- 2020-11-24 CA CA3162281A patent/CA3162281A1/en active Pending
- 2020-11-24 AU AU2020392087A patent/AU2020392087B2/en active Active
- 2020-11-24 KR KR1020237037455A patent/KR20230154292A/ko active Pending
- 2020-11-24 JO JOP/2022/0125A patent/JOP20220125A1/ar unknown
- 2020-11-24 IL IL293191A patent/IL293191B2/en unknown
- 2020-11-24 CN CN202410291075.3A patent/CN118161500A/zh active Pending
- 2020-11-24 EP EP20828193.1A patent/EP4065223A1/en active Pending
- 2020-11-24 CR CR20220308A patent/CR20220308A/es unknown
- 2020-11-24 KR KR1020227021152A patent/KR102598203B1/ko active Active
- 2020-11-25 TW TW109141315A patent/TWI815061B/zh active
- 2020-11-25 UY UY0001038971A patent/UY38971A/es unknown
- 2020-11-25 TW TW112142068A patent/TWI867822B/zh active
- 2020-11-25 AR ARP200103274A patent/AR120556A1/es unknown
-
2021
- 2021-03-16 US US17/203,457 patent/US20210221824A1/en not_active Abandoned
-
2022
- 2022-05-24 SA SA522432710A patent/SA522432710B1/ar unknown
- 2022-05-24 CL CL2022001357A patent/CL2022001357A1/es unknown
- 2022-06-22 CO CONC2022/0008690A patent/CO2022008690A2/es unknown
- 2022-11-18 US US18/056,863 patent/US12448396B2/en active Active
-
2023
- 2023-03-27 JP JP2023049452A patent/JP7698676B2/ja active Active
- 2023-08-22 CL CL2023002486A patent/CL2023002486A1/es unknown
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