JP2023058608A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023058608A5 JP2023058608A5 JP2023017816A JP2023017816A JP2023058608A5 JP 2023058608 A5 JP2023058608 A5 JP 2023058608A5 JP 2023017816 A JP2023017816 A JP 2023017816A JP 2023017816 A JP2023017816 A JP 2023017816A JP 2023058608 A5 JP2023058608 A5 JP 2023058608A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- subject
- biomarkers
- hae
- levels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000090 biomarker Substances 0.000 claims 15
- 238000000034 method Methods 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 11
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 206010019860 Hereditary angioedema Diseases 0.000 claims 7
- 201000010099 disease Diseases 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 7
- 239000000126 substance Substances 0.000 claims 6
- 102100038222 60 kDa heat shock protein, mitochondrial Human genes 0.000 claims 4
- 108010058432 Chaperonin 60 Proteins 0.000 claims 4
- 239000011230 binding agent Substances 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 4
- 230000004913 activation Effects 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 102000004899 14-3-3 Proteins Human genes 0.000 claims 2
- 238000002965 ELISA Methods 0.000 claims 2
- 101000818893 Homo sapiens 14-3-3 protein beta/alpha Proteins 0.000 claims 2
- 101000964898 Homo sapiens 14-3-3 protein zeta/delta Proteins 0.000 claims 2
- 102100033474 Interleukin-36 alpha Human genes 0.000 claims 2
- 108050004801 Interleukin-36 alpha Proteins 0.000 claims 2
- 108700012928 MAPK14 Proteins 0.000 claims 2
- 102000006404 Mitochondrial Proteins Human genes 0.000 claims 2
- 108010058682 Mitochondrial Proteins Proteins 0.000 claims 2
- 102100023482 Mitogen-activated protein kinase 14 Human genes 0.000 claims 2
- 102100034943 Peptidyl-prolyl cis-trans isomerase F, mitochondrial Human genes 0.000 claims 2
- 101710191011 Peptidyl-prolyl cis-trans isomerase F, mitochondrial Proteins 0.000 claims 2
- 102000001253 Protein Kinase Human genes 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 230000002438 mitochondrial effect Effects 0.000 claims 2
- 108060006633 protein kinase Proteins 0.000 claims 2
- 102100021408 14-3-3 protein beta/alpha Human genes 0.000 claims 1
- 102100040685 14-3-3 protein zeta/delta Human genes 0.000 claims 1
- 102100024736 ATP-dependent RNA helicase DDX19B Human genes 0.000 claims 1
- 101710113909 ATP-dependent RNA helicase DDX19B Proteins 0.000 claims 1
- 102100026761 Eukaryotic translation initiation factor 5A-1 Human genes 0.000 claims 1
- 101710126270 Eukaryotic translation initiation factor 5A-1 Proteins 0.000 claims 1
- 108010051975 Glycogen Synthase Kinase 3 beta Proteins 0.000 claims 1
- 102100022975 Glycogen synthase kinase-3 alpha Human genes 0.000 claims 1
- 102100038104 Glycogen synthase kinase-3 beta Human genes 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 claims 1
- 108010049611 glycogen synthase kinase 3 alpha Proteins 0.000 claims 1
- 238000003119 immunoblot Methods 0.000 claims 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023218832A JP7693788B2 (ja) | 2016-09-16 | 2023-12-26 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
| JP2025094023A JP2025124852A (ja) | 2016-09-16 | 2025-06-05 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395712P | 2016-09-16 | 2016-09-16 | |
| US62/395,712 | 2016-09-16 | ||
| US201762518492P | 2017-06-12 | 2017-06-12 | |
| US62/518,492 | 2017-06-12 | ||
| JP2019514252A JP7225089B2 (ja) | 2016-09-16 | 2017-09-15 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514252A Division JP7225089B2 (ja) | 2016-09-16 | 2017-09-15 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023218832A Division JP7693788B2 (ja) | 2016-09-16 | 2023-12-26 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023058608A JP2023058608A (ja) | 2023-04-25 |
| JP2023058608A5 true JP2023058608A5 (https=) | 2023-07-19 |
| JP7412616B2 JP7412616B2 (ja) | 2024-01-12 |
Family
ID=59974881
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514252A Active JP7225089B2 (ja) | 2016-09-16 | 2017-09-15 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
| JP2023017816A Active JP7412616B2 (ja) | 2016-09-16 | 2023-02-08 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
| JP2023218832A Active JP7693788B2 (ja) | 2016-09-16 | 2023-12-26 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
| JP2025094023A Pending JP2025124852A (ja) | 2016-09-16 | 2025-06-05 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514252A Active JP7225089B2 (ja) | 2016-09-16 | 2017-09-15 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023218832A Active JP7693788B2 (ja) | 2016-09-16 | 2023-12-26 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
| JP2025094023A Pending JP2025124852A (ja) | 2016-09-16 | 2025-06-05 | 接触活性化系に関連する疾患のタンパク質バイオマーカー |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11815516B2 (https=) |
| EP (1) | EP3513196B1 (https=) |
| JP (4) | JP7225089B2 (https=) |
| KR (3) | KR102806918B1 (https=) |
| CN (2) | CN109716138B (https=) |
| AU (3) | AU2017325983B2 (https=) |
| BR (1) | BR112019005179A2 (https=) |
| CA (1) | CA3037154A1 (https=) |
| CO (1) | CO2019002599A2 (https=) |
| IL (2) | IL265195B2 (https=) |
| MX (2) | MX2019002932A (https=) |
| WO (1) | WO2018053244A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017325986B2 (en) | 2016-09-16 | 2023-12-14 | Takeda Pharmaceutical Company Limited | Metabolite biomarkers for diseases associated with the contact activation system |
| CN113092769A (zh) * | 2019-12-23 | 2021-07-09 | 首都医科大学附属北京世纪坛医院 | 尿液补体c4-a及其多肽片段在过敏性疾病中的应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| PT739355E (pt) | 1994-01-11 | 2005-01-31 | Dyax Corp | Proteinas de 'dominio de kunitz' inibidoras de calicreina e seus analogos |
| US7399837B2 (en) * | 1995-12-22 | 2008-07-15 | Smithkline Beecham Corporation | Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders |
| JP2001174463A (ja) * | 1999-12-17 | 2001-06-29 | Hsp Research Institute Inc | 自己免疫疾患又は腫瘍の診断方法 |
| AU2001274888A1 (en) * | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20040152633A1 (en) | 2001-05-31 | 2004-08-05 | Jorgensen Marianne Ulrich | Kunitz-type sequences and polypeptides |
| WO2003103475A2 (en) | 2002-06-07 | 2003-12-18 | Dyax Corp. | Prevention and reduction of blood loss |
| JP4399593B2 (ja) * | 2004-04-01 | 2010-01-20 | 国立大学法人 千葉大学 | インフルエンザ脳症の検査法、及び、ヒト髄液中に発現するタンパク質からなるマーカ、診断薬、診断キット |
| EP1598428A1 (en) * | 2004-05-18 | 2005-11-23 | Georg Dewald | Methods and kits to detect Hereditary angioedema type III |
| EP2500031A3 (en) | 2005-02-24 | 2012-12-26 | Joslin Diabetes Center, Inc. | Compositions and Methods for Treating Vascular Permeability |
| GB2428240A (en) * | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
| WO2007059966A1 (en) * | 2005-11-23 | 2007-05-31 | Georg Dewald | Detection and treatment of drug associated angioedema |
| US7276480B1 (en) | 2005-12-30 | 2007-10-02 | Dyax Corp. | Prevention and reduction of blood loss |
| US20090104605A1 (en) * | 2006-12-14 | 2009-04-23 | Gary Siuzdak | Diagnosis of sepsis |
| US20110159011A1 (en) | 2008-08-28 | 2011-06-30 | Wyeth Llc | Uses of il-22, il-17, and il-1 family cytokines in autoimmune diseases |
| US8883153B2 (en) * | 2009-03-27 | 2014-11-11 | The Research for The State University of New York | Methods for preventing and treating angioedema |
| EP3459564B1 (en) | 2010-01-06 | 2021-10-27 | Takeda Pharmaceutical Company Limited | Plasma kallikrein binding proteins |
| US9102942B2 (en) * | 2010-02-04 | 2015-08-11 | EWHA University—Industry Collaboration Foundation | Pharmaceutical composition for inhibiting abnormal proliferation of cells |
| JP2011226882A (ja) * | 2010-04-19 | 2011-11-10 | Kitasato Institute | 泌尿器系疾患マーカー及びその抗体、並びに泌尿器系疾患診断用キット |
| CA2823776A1 (en) | 2011-01-06 | 2012-07-12 | Dyax Corp. | Plasma kallikrein binding proteins |
| WO2012170947A2 (en) * | 2011-06-10 | 2012-12-13 | Isis Pharmaceuticals, Inc. | Methods for modulating factor 12 expression |
| US20130102486A1 (en) * | 2011-10-20 | 2013-04-25 | The Board Of Trustees Of The Leland Stanford Junior University | Perp as a prognostic and diagnostic marker for dysplasia and cancer |
| EP2946206B1 (en) * | 2013-01-20 | 2019-01-09 | Dyax Corp. | Evaluation, assays and treatment of pkal-mediated disorders |
| WO2014113712A1 (en) * | 2013-01-20 | 2014-07-24 | Dyax Corp. | Evaluation and treatment of bradykinin-mediated disorders |
| TWI755763B (zh) * | 2013-06-04 | 2022-02-21 | 美商再生元醫藥公司 | 藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法 |
| JP6757252B2 (ja) * | 2013-10-21 | 2020-09-16 | ダイアックス コーポレーション | 血漿カリクレイン系バイオマーカーを決定するためのアッセイ |
| CA2927695C (en) * | 2013-10-21 | 2022-03-01 | Dyax Corp. | Diagnosis and treatment of autoimmune diseases |
| AU2015209481C1 (en) * | 2014-01-21 | 2020-10-29 | Takeda Pharmaceutical Company Limited | Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema |
| EP3132053B1 (en) * | 2014-04-15 | 2020-09-30 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Differential diagnosis of eczema and psoriasis |
| EA201990730A1 (ru) | 2016-09-16 | 2019-08-30 | Дайэкс Корп. | Рнк-биомаркеры для наследственного ангионевротического отека |
| AU2017325986B2 (en) | 2016-09-16 | 2023-12-14 | Takeda Pharmaceutical Company Limited | Metabolite biomarkers for diseases associated with the contact activation system |
-
2017
- 2017-09-15 KR KR1020237009552A patent/KR102806918B1/ko active Active
- 2017-09-15 CN CN201780057056.2A patent/CN109716138B/zh active Active
- 2017-09-15 EP EP17777136.7A patent/EP3513196B1/en active Active
- 2017-09-15 JP JP2019514252A patent/JP7225089B2/ja active Active
- 2017-09-15 CA CA3037154A patent/CA3037154A1/en active Pending
- 2017-09-15 IL IL265195A patent/IL265195B2/en unknown
- 2017-09-15 US US16/333,155 patent/US11815516B2/en active Active
- 2017-09-15 IL IL315799A patent/IL315799A/en unknown
- 2017-09-15 AU AU2017325983A patent/AU2017325983B2/en active Active
- 2017-09-15 BR BR112019005179-1A patent/BR112019005179A2/pt unknown
- 2017-09-15 CN CN202311187493.XA patent/CN117192130A/zh active Pending
- 2017-09-15 KR KR1020197010801A patent/KR102513485B1/ko active Active
- 2017-09-15 MX MX2019002932A patent/MX2019002932A/es unknown
- 2017-09-15 WO PCT/US2017/051749 patent/WO2018053244A1/en not_active Ceased
- 2017-09-15 KR KR1020257015097A patent/KR20250073510A/ko active Pending
-
2019
- 2019-03-13 MX MX2024009782A patent/MX2024009782A/es unknown
- 2019-03-21 CO CONC2019/0002599A patent/CO2019002599A2/es unknown
-
2023
- 2023-02-08 JP JP2023017816A patent/JP7412616B2/ja active Active
- 2023-10-04 US US18/480,709 patent/US20240142468A1/en active Pending
- 2023-12-26 JP JP2023218832A patent/JP7693788B2/ja active Active
-
2024
- 2024-03-07 AU AU2024201506A patent/AU2024201506B2/en active Active
-
2025
- 2025-06-05 JP JP2025094023A patent/JP2025124852A/ja active Pending
-
2026
- 2026-02-19 AU AU2026201253A patent/AU2026201253A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Larsson et al. | The effects of age and gender on plasma levels of 63 cytokines | |
| Cehofski et al. | Aqueous fibronectin correlates with severity of macular edema and visual acuity in patients with branch retinal vein occlusion: a proteome study | |
| CN109716137B (zh) | 用于与接触活化系统相关的疾病的代谢产物生物标记 | |
| JP2023058608A5 (https=) | ||
| JP2016513253A (ja) | 急性呼吸促迫症候群（ａｒｄｓ）関連バイオマーカーを測定する方法、患者におけるａｒｄｓの進行および治療をモニターする方法 | |
| Bartosik‐Psujek et al. | Total tau and S100b proteins in different types of multiple sclerosis and during immunosuppressive treatment with mitoxantrone | |
| JP6732914B2 (ja) | トリプトファニルｔＲＮＡ合成酵素を利用した感染症又は感染合併症の診断用組成物と診断マーカー検出方法 | |
| Shin et al. | Identification of ganglioside GM 2 activator playing a role in cancer cell migration through proteomic analysis of breast cancer secretomes | |
| JP6645981B2 (ja) | サーマルシフトアッセイを使用して薬物反応の減少の指標となるバイオマーカーを識別するための方法 | |
| CN101023356A (zh) | 诊断肝纤维化的方法 | |
| Matsumoto et al. | Proteomic comparison between abdominal and thoracic aortic aneurysms | |
| EP3189337A1 (en) | Biomarker signatures for lyme disease and methods of use thereof | |
| Dong et al. | Proteomic profiling to identify blood biomarkers predictive of response to azithromycin in children and adolescents with cystic fibrosis | |
| US20160223537A1 (en) | Identification of novel biomarkers of flares of systemic lupus erythematosus | |
| KR20040012854A (ko) | 미생물의 동정 방법 | |
| KR102681006B1 (ko) | 뇌의 레닌-안지오텐신 시스템 인자를 이용한 알츠하이머병의 진단 방법 | |
| SI24638A (sl) | Fluorometrična imunska metoda za določanje protiteles proti dvojnoverižni DNA | |
| US20140051598A1 (en) | Diagnostic biomarker to predict women at risk for preterm delivery | |
| Korte et al. | Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus | |
| JP2019529906A5 (https=) | ||
| Barenghi et al. | Saliva: challenges, possibilities, and limits of the diagnostic use Part 2–pre-analytical and analytical aspects | |
| JP5876673B2 (ja) | 精神障害の診断方法および診断薬キット | |
| US20130115638A1 (en) | Method and rapid test for determining the fertility of sperm | |
| JP7307479B2 (ja) | ＩｇＡ腎症診断用キット | |
| JP2011107116A (ja) | 脳梗塞の検査方法 |