JP2023053328A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023053328A5 JP2023053328A5 JP2023021295A JP2023021295A JP2023053328A5 JP 2023053328 A5 JP2023053328 A5 JP 2023053328A5 JP 2023021295 A JP2023021295 A JP 2023021295A JP 2023021295 A JP2023021295 A JP 2023021295A JP 2023053328 A5 JP2023053328 A5 JP 2023053328A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- sequence shown
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024062451A JP7696658B2 (ja) | 2017-12-24 | 2024-04-09 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017247109 | 2017-12-24 | ||
| JP2017247109 | 2017-12-24 | ||
| JP2019560545A JP7233720B2 (ja) | 2017-12-24 | 2018-12-19 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
| PCT/JP2018/046888 WO2019124468A1 (ja) | 2017-12-24 | 2018-12-19 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019560545A Division JP7233720B2 (ja) | 2017-12-24 | 2018-12-19 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062451A Division JP7696658B2 (ja) | 2017-12-24 | 2024-04-09 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023053328A JP2023053328A (ja) | 2023-04-12 |
| JP2023053328A5 true JP2023053328A5 (https=) | 2023-10-25 |
| JP7475088B2 JP7475088B2 (ja) | 2024-04-26 |
Family
ID=66993541
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019560545A Active JP7233720B2 (ja) | 2017-12-24 | 2018-12-19 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
| JP2023021295A Active JP7475088B2 (ja) | 2017-12-24 | 2023-02-15 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
| JP2024062451A Active JP7696658B2 (ja) | 2017-12-24 | 2024-04-09 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019560545A Active JP7233720B2 (ja) | 2017-12-24 | 2018-12-19 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024062451A Active JP7696658B2 (ja) | 2017-12-24 | 2024-04-09 | ヒトメソセリンを特異的に認識する細胞表面分子、ｉｌ－７、及びｃｃｌ１９を発現する免疫担当細胞 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20200323920A1 (https=) |
| EP (1) | EP3730612B1 (https=) |
| JP (3) | JP7233720B2 (https=) |
| KR (1) | KR102830462B1 (https=) |
| CN (1) | CN111511911B (https=) |
| AU (1) | AU2018388079B2 (https=) |
| BR (1) | BR112020012848A2 (https=) |
| CA (1) | CA3086658A1 (https=) |
| EA (1) | EA202091488A1 (https=) |
| FI (1) | FI3730612T3 (https=) |
| IL (1) | IL275453B2 (https=) |
| MX (1) | MX2020006666A (https=) |
| PT (1) | PT3730612T (https=) |
| SA (1) | SA520412282B1 (https=) |
| SG (1) | SG11202005908WA (https=) |
| TW (1) | TWI811278B (https=) |
| WO (1) | WO2019124468A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112771166B (zh) * | 2018-08-31 | 2025-03-04 | 诺伊尔免疫生物科技株式会社 | 表达car的t细胞和car表达载体 |
| CN120484122A (zh) | 2019-01-11 | 2025-08-15 | 米纳瓦生物技术公司 | 抗可变muc1*抗体及其用途 |
| JP7436056B2 (ja) * | 2019-10-28 | 2024-02-21 | ノイルイミューン・バイオテック株式会社 | がんを治療するための医薬、組み合わせ医薬、医薬組成物、免疫応答性細胞、核酸送達媒体、及び製品 |
| CN111235113A (zh) * | 2020-01-21 | 2020-06-05 | 南京北恒生物科技有限公司 | 包含嵌合抗原受体的免疫细胞及其用途 |
| JP7138989B1 (ja) * | 2020-08-04 | 2022-09-20 | セレンジーン インコーポレイテッド | メソテリンに特異的に結合する抗メソテリンキメラ抗原受容体 |
| KR102770127B1 (ko) * | 2020-10-28 | 2025-02-21 | 주식회사 티에스디라이프사이언스 | 이종 면역세포에 대한 화학주성을 유도하는 형질전환된 면역세포 |
| CN113380324B (zh) * | 2021-05-17 | 2023-06-27 | 西安交通大学 | 一种T细胞受体序列motif组合识别检测方法、存储介质及设备 |
| EP4377355A4 (en) * | 2021-07-29 | 2025-06-18 | Takeda Pharmaceutical Company Limited | CAR-EXPRESSING IMMUNE CELLS WITH SPECIFIC TARGETTING OF MESOTHELIN AND USES THEREOF |
| AU2022318416A1 (en) | 2021-07-29 | 2024-01-25 | Takeda Pharmaceutical Company Limited | Engineered immune cell that specifically targets mesothelin and uses thereof |
| CN113651893B (zh) * | 2021-08-12 | 2023-08-01 | 上海生物制品研究所有限责任公司 | 联合her2和meso双靶点car-t载体及其构建方法和在癌症中的应用 |
| CN119923410A (zh) * | 2022-07-28 | 2025-05-02 | 莱蒂恩技术公司 | 用于治疗实体瘤的嵌合抗原受体治疗 |
| US20240261406A1 (en) | 2023-02-02 | 2024-08-08 | Minerva Biotechnologies Corporation | Chimeric antigen receptor compositions and methods for treating muc1* diseases |
| WO2025255291A1 (en) * | 2024-06-07 | 2025-12-11 | Memorial Sloan-Kettering Cancer Center | Chimeric antigen receptors targeting mesothelin and use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2928287B2 (ja) | 1988-09-29 | 1999-08-03 | 協和醗酵工業株式会社 | 新規ポリペプチド |
| US7795411B2 (en) * | 2006-10-05 | 2010-09-14 | Fred Hutchinson Cancer Research Center | Vectors for expressing in vivo biotinylated recombinant proteins |
| MX2010005603A (es) * | 2007-11-26 | 2010-08-02 | Bayer Schering Pharma Ag | Anticuerpos antimesotelina y usos de los mismos. |
| CA2718321A1 (en) | 2008-03-27 | 2009-10-01 | Dimiter S. Dimitrov | Human anti-mesothelin monoclonal antibodies |
| WO2010028795A1 (en) * | 2008-09-10 | 2010-03-18 | F. Hoffmann-La Roche Ag | Multivalent antibodies |
| CA2776143A1 (en) * | 2009-10-01 | 2011-04-07 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
| AR079944A1 (es) * | 2010-01-20 | 2012-02-29 | Boehringer Ingelheim Int | Anticuerpo neutralizante de la actividad de un anticoagulante |
| US9272002B2 (en) | 2011-10-28 | 2016-03-01 | The Trustees Of The University Of Pennsylvania | Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting |
| EP4166148B1 (en) | 2014-06-06 | 2026-02-18 | Memorial Sloan-Kettering Cancer Center | Mesothelin-targeted chimeric antigen receptors and uses thereof |
| SI3597742T1 (sl) * | 2014-10-09 | 2022-11-30 | Yamaguchi University | CAR ekspresijski vektor in T celice, ki izražajo CAR |
| CA3017442A1 (en) * | 2016-03-17 | 2017-09-21 | Yamaguchi University | Immunocompetent cell and expression vector expressing regulatory factors of immune function |
| EP3439675A4 (en) * | 2016-04-08 | 2019-12-18 | Purdue Research Foundation | METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY |
| KR102790597B1 (ko) * | 2017-10-10 | 2025-04-07 | 고쿠리츠다이가쿠호우진 야마구치 다이가쿠 | 메모리 기능을 갖는 t세포 또는 b세포의 증강제, 악성 종양 재발 억제제 및 t세포 또는 b세포에 메모리 기능을 유도하는 유도제 |
-
2018
- 2018-12-19 WO PCT/JP2018/046888 patent/WO2019124468A1/ja not_active Ceased
- 2018-12-19 FI FIEP18892953.3T patent/FI3730612T3/fi active
- 2018-12-19 BR BR112020012848-1A patent/BR112020012848A2/pt unknown
- 2018-12-19 CA CA3086658A patent/CA3086658A1/en active Pending
- 2018-12-19 AU AU2018388079A patent/AU2018388079B2/en active Active
- 2018-12-19 JP JP2019560545A patent/JP7233720B2/ja active Active
- 2018-12-19 KR KR1020207019665A patent/KR102830462B1/ko active Active
- 2018-12-19 CN CN201880082572.5A patent/CN111511911B/zh active Active
- 2018-12-19 US US16/956,855 patent/US20200323920A1/en not_active Abandoned
- 2018-12-19 IL IL275453A patent/IL275453B2/en unknown
- 2018-12-19 SG SG11202005908WA patent/SG11202005908WA/en unknown
- 2018-12-19 PT PT188929533T patent/PT3730612T/pt unknown
- 2018-12-19 EA EA202091488A patent/EA202091488A1/ru unknown
- 2018-12-19 EP EP18892953.3A patent/EP3730612B1/en active Active
- 2018-12-19 MX MX2020006666A patent/MX2020006666A/es unknown
- 2018-12-20 TW TW107146245A patent/TWI811278B/zh active
-
2020
- 2020-06-20 SA SA520412282A patent/SA520412282B1/ar unknown
-
2023
- 2023-02-15 JP JP2023021295A patent/JP7475088B2/ja active Active
-
2024
- 2024-01-10 US US18/409,191 patent/US20240139248A1/en not_active Abandoned
- 2024-04-09 JP JP2024062451A patent/JP7696658B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023053328A5 (https=) | ||
| CN113784732B (zh) | 靶向bcma的工程化免疫细胞及其用途 | |
| TWI728308B (zh) | 一種結合ｂｃｍａ的嵌合抗原受體（ｃａｒ）及其應用 | |
| CN113784733B (zh) | 靶向bcma的工程化免疫细胞及其用途 | |
| JP6285553B2 (ja) | 抗ｃｄ３０キメラ抗原受容体およびその使用 | |
| CN108603200B (zh) | 优化的慢病毒转移载体及其用途 | |
| JP2023139070A5 (https=) | ||
| JP2023514385A (ja) | 新規キメラ抗原受容体とその使用 | |
| EP4729532A2 (en) | Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20 | |
| WO2019149250A1 (zh) | 一种结合bcma的嵌合抗原受体(car)及其应用 | |
| KR20230095083A (ko) | Cd7 표적의 키메라 항원 수용체 및 이의 용도 | |
| JP7404279B2 (ja) | 様々な構築物最適化を備えたｔ細胞抗原カプラ | |
| CN110157738B (zh) | 靶向cd19和cd22的工程化免疫细胞及其应用 | |
| JP2024505955A (ja) | 新型キメラ抗原受容体及びその使用 | |
| CN108138148A (zh) | T细胞的激活和扩增 | |
| KR20230066007A (ko) | 신규한 보조자극 도메인을 포함하는 키메라 항원 수용체 및 이의 용도 | |
| CN115216449A (zh) | 工程化免疫细胞及其用途 | |
| WO2018111340A1 (en) | Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells | |
| JP2024510898A (ja) | Ｒｏｒ１を標的とするキメラ抗原受容体 | |
| CN117004604A (zh) | 一种ciita基因被敲除的工程化免疫细胞及其用途 | |
| JP7849891B2 (ja) | Ｃｅａを認識するキメラ抗原受容体（ｃａｒ）発現細胞 | |
| CN109554349B (zh) | Pd-1基因表达沉默的工程化免疫细胞 | |
| CN111499766B (zh) | 针对慢性淋巴细胞白血病的免疫效应细胞、其制备方法和应用 | |
| CN115785279A (zh) | 包含新型共刺激结构域的嵌合抗原受体及其用途 | |
| CN115873801A (zh) | 工程化免疫细胞及其用途 |