SA520412282B1 - خلية مؤهلة مناعيًا تعبر عن جزيء سطح خلية يتعرف على وجه التحديد على ccl19 il-7 ميزوثيلين بشري، - Google Patents

خلية مؤهلة مناعيًا تعبر عن جزيء سطح خلية يتعرف على وجه التحديد على ccl19 il-7 ميزوثيلين بشري،

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Publication number
SA520412282B1
SA520412282B1 SA520412282A SA520412282A SA520412282B1 SA 520412282 B1 SA520412282 B1 SA 520412282B1 SA 520412282 A SA520412282 A SA 520412282A SA 520412282 A SA520412282 A SA 520412282A SA 520412282 B1 SA520412282 B1 SA 520412282B1
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SA
Saudi Arabia
Prior art keywords
mesothelin
surface molecule
immunocompetent
cell surface
cell
Prior art date
Application number
SA520412282A
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Arabic (ar)
English (en)
Inventor
تامادا كوجي
اداتشي كيشي
ساكودا يوكيمي
Original Assignee
نويلي-ايمون بيوتيك, انك.
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Application filed by نويلي-ايمون بيوتيك, انك. filed Critical نويلي-ايمون بيوتيك, انك.
Publication of SA520412282B1 publication Critical patent/SA520412282B1/ar

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/0636—T lymphocytes
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5418—IL-7
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    • A61K35/14—Blood; Artificial blood
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    • A—HUMAN NECESSITIES
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    • A61K40/4255—Mesothelin [MSLN]
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SA520412282A 2017-12-24 2020-06-20 خلية مؤهلة مناعيًا تعبر عن جزيء سطح خلية يتعرف على وجه التحديد على ccl19 il-7 ميزوثيلين بشري، SA520412282B1 (ar)

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JP2017247109 2017-12-24

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SA520412282B1 true SA520412282B1 (ar) 2023-11-09

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US (2) US20200323920A1 (https=)
EP (1) EP3730612B1 (https=)
JP (3) JP7233720B2 (https=)
KR (1) KR102830462B1 (https=)
CN (1) CN111511911B (https=)
AU (1) AU2018388079B2 (https=)
BR (1) BR112020012848A2 (https=)
CA (1) CA3086658A1 (https=)
EA (1) EA202091488A1 (https=)
IL (1) IL275453B2 (https=)
MX (1) MX2020006666A (https=)
PT (1) PT3730612T (https=)
SA (1) SA520412282B1 (https=)
SG (1) SG11202005908WA (https=)
TW (1) TWI811278B (https=)
WO (1) WO2019124468A1 (https=)

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JP7436056B2 (ja) * 2019-10-28 2024-02-21 ノイルイミューン・バイオテック株式会社 がんを治療するための医薬、組み合わせ医薬、医薬組成物、免疫応答性細胞、核酸送達媒体、及び製品
CN111235113A (zh) * 2020-01-21 2020-06-05 南京北恒生物科技有限公司 包含嵌合抗原受体的免疫细胞及其用途
JP7138989B1 (ja) 2020-08-04 2022-09-20 セレンジーン インコーポレイテッド メソテリンに特異的に結合する抗メソテリンキメラ抗原受容体
CN116391030A (zh) * 2020-10-28 2023-07-04 Tsd 生命科学有限公司 诱导异质免疫细胞趋化的转化免疫细胞
CN113380324B (zh) * 2021-05-17 2023-06-27 西安交通大学 一种T细胞受体序列motif组合识别检测方法、存储介质及设备
CA3227581A1 (en) 2021-07-29 2023-02-02 Takeda Pharmaceutical Company Limited Engineered immune cell that specifically targets mesothelin and uses thereof
CA3227745A1 (en) * 2021-07-29 2023-02-02 Takeda Pharmaceutical Company Limited Car-expressing immune cells that specifically target mesothelin and uses thereof
CN113651893B (zh) * 2021-08-12 2023-08-01 上海生物制品研究所有限责任公司 联合her2和meso双靶点car-t载体及其构建方法和在癌症中的应用
AU2023314413A1 (en) 2022-07-28 2025-02-13 Lentigen Technology, Inc. Chimeric antigen receptor therapies for treating solid tumors
US20240261406A1 (en) 2023-02-02 2024-08-08 Minerva Biotechnologies Corporation Chimeric antigen receptor compositions and methods for treating muc1* diseases
WO2025255291A1 (en) * 2024-06-07 2025-12-11 Memorial Sloan-Kettering Cancer Center Chimeric antigen receptors targeting mesothelin and use thereof

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JP2023053328A (ja) 2023-04-12
EP3730612A1 (en) 2020-10-28
EP3730612A4 (en) 2021-09-01
JP7696658B2 (ja) 2025-06-23
SG11202005908WA (en) 2020-07-29
EA202091488A1 (ru) 2020-09-23
CN111511911A (zh) 2020-08-07
PT3730612T (pt) 2026-03-30
CA3086658A1 (en) 2019-06-27
IL275453A (en) 2020-08-31
WO2019124468A1 (ja) 2019-06-27
TWI811278B (zh) 2023-08-11
IL275453B2 (en) 2024-06-01
TW201930589A (zh) 2019-08-01
AU2018388079B2 (en) 2024-11-14
US20200323920A1 (en) 2020-10-15
JP7233720B2 (ja) 2023-03-07
BR112020012848A2 (pt) 2021-01-26
EP3730612B1 (en) 2026-02-04
US20240139248A1 (en) 2024-05-02
IL275453B1 (en) 2024-02-01
AU2018388079A1 (en) 2020-07-16
MX2020006666A (es) 2020-08-31
JP2024086826A (ja) 2024-06-28
KR20200103708A (ko) 2020-09-02
KR102830462B1 (ko) 2025-07-04
JP7475088B2 (ja) 2024-04-26
JPWO2019124468A1 (ja) 2021-01-21

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