JP2023021316A5 - - Google Patents
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- Publication number
- JP2023021316A5 JP2023021316A5 JP2022199375A JP2022199375A JP2023021316A5 JP 2023021316 A5 JP2023021316 A5 JP 2023021316A5 JP 2022199375 A JP2022199375 A JP 2022199375A JP 2022199375 A JP2022199375 A JP 2022199375A JP 2023021316 A5 JP2023021316 A5 JP 2023021316A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pyridyl
- trifluoromethyl
- phenyl
- pyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17187560 | 2017-08-23 | ||
| EP17187560.2 | 2017-08-23 | ||
| JP2020510114A JP7201260B2 (ja) | 2017-08-23 | 2018-08-23 | ピリジンアミン－ピリドンおよびピリミジンアミン－ピリドン化合物 |
| PCT/EP2018/072790 WO2019038389A1 (en) | 2017-08-23 | 2018-08-23 | PYRIDINAMINE-PYRIDONE AND PYRIMIDINAMINE-PYRIDONE COMPOUNDS |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020510114A Division JP7201260B2 (ja) | 2017-08-23 | 2018-08-23 | ピリジンアミン－ピリドンおよびピリミジンアミン－ピリドン化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023021316A JP2023021316A (ja) | 2023-02-10 |
| JP2023021316A5 true JP2023021316A5 (https=) | 2023-09-26 |
Family
ID=59686885
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020510114A Active JP7201260B2 (ja) | 2017-08-23 | 2018-08-23 | ピリジンアミン－ピリドンおよびピリミジンアミン－ピリドン化合物 |
| JP2022199375A Ceased JP2023021316A (ja) | 2017-08-23 | 2022-12-14 | ピリジンアミン－ピリドンおよびピリミジンアミン－ピリドン化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020510114A Active JP7201260B2 (ja) | 2017-08-23 | 2018-08-23 | ピリジンアミン－ピリドンおよびピリミジンアミン－ピリドン化合物 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US11208423B2 (https=) |
| EP (2) | EP4169581A1 (https=) |
| JP (2) | JP7201260B2 (https=) |
| KR (1) | KR102730753B1 (https=) |
| CN (3) | CN111094271B (https=) |
| AU (2) | AU2018320418B2 (https=) |
| CY (1) | CY1125728T1 (https=) |
| DK (1) | DK3672948T3 (https=) |
| ES (1) | ES2929424T3 (https=) |
| FI (1) | FI3672948T3 (https=) |
| HR (1) | HRP20221454T1 (https=) |
| HU (1) | HUE060805T2 (https=) |
| IL (3) | IL292488B2 (https=) |
| LT (1) | LT3672948T (https=) |
| PL (1) | PL3672948T3 (https=) |
| PT (1) | PT3672948T (https=) |
| RS (1) | RS63795B1 (https=) |
| SI (1) | SI3672948T1 (https=) |
| SM (1) | SMT202200493T1 (https=) |
| TW (2) | TW202325302A (https=) |
| WO (1) | WO2019038389A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111094271B (zh) * | 2017-08-23 | 2023-02-28 | 思普瑞特生物科学公司 | 吡啶胺-吡啶酮化合物和嘧啶胺-吡啶酮化合物 |
| BR112020012651A2 (pt) | 2017-12-22 | 2020-12-01 | Ravenna Pharmaceuticals, Inc. | compostos derivados de aril-bipiridina amina como inibidores da fosfatidilinositol fosfato quinase, composição farmacêutica compreendendo os mesmos e usos terapêuticos dos ditos compostos |
| WO2021113506A1 (en) * | 2019-12-04 | 2021-06-10 | Chdi Foundation, Inc. | Atm kinase inhibitors and compositions and methods of use thereof |
| EP4251163A1 (en) | 2020-11-25 | 2023-10-04 | Deciphera Pharmaceuticals, LLC | Anti-viral activity of vps34 inhibitors |
| EP4251165A1 (en) * | 2020-11-25 | 2023-10-04 | Deciphera Pharmaceuticals, LLC | Morpholino derivatives as vsp34 inhibitors for use in the treatment of a viral infection |
| WO2022115562A1 (en) | 2020-11-25 | 2022-06-02 | Deciphera Pharmaceuticals, Llc | Morpholino derivatives as vsp34 inhibitors for use in the treatment of a viral infection |
| US20240277852A1 (en) * | 2021-05-20 | 2024-08-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors and degraders of pip4k protein |
| AU2022326573A1 (en) * | 2021-08-13 | 2024-02-15 | Deciphera Pharmaceuticals, Llc | Combination therapy of vps34 inhibitors and sting agonist for use in the treatment of cancer |
| JP2025513452A (ja) * | 2022-04-22 | 2025-04-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | 疼痛の治療のためのヘテロアリール化合物 |
| US20250236609A1 (en) * | 2023-12-13 | 2025-07-24 | Deciphera Pharmaceuticals, Llc | Vps34 inhibitors and methods of use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2485166A1 (en) * | 2002-05-21 | 2003-12-04 | Amgen Inc. | Substituted pyrimidinone and pyridinone compounds |
| AU2011346567A1 (en) | 2010-12-21 | 2013-07-25 | Novartis Ag | Bi-heteroaryl compounds as Vps34 inhibitors |
| DK2655375T3 (en) | 2010-12-23 | 2015-03-09 | Sanofi Sa | PYRIMIDINON DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF |
| GB201120317D0 (en) | 2011-11-24 | 2012-01-04 | Queen Mary & Westfield College | Screening method |
| FR2992314B1 (fr) | 2012-06-22 | 2015-10-16 | Sanofi Sa | Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one et 1,2,3,4-tetrahydro-pyrimido{1,2-a}pyrimidin-6-one comportant une morpholine substituee, leur preparation et leur utilisation pharmaceutique |
| AU2015206652A1 (en) | 2014-01-14 | 2016-08-04 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2015108881A1 (en) | 2014-01-14 | 2015-07-23 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| MA39822A (fr) | 2014-04-03 | 2018-02-06 | Janssen Pharmaceutica Nv | Dérivés de pyrimidine bicycle |
| MA39823A (fr) | 2014-04-03 | 2018-01-09 | Janssen Pharmaceutica Nv | Dérivés de pyridine macrocyclique |
| WO2016001789A1 (en) | 2014-06-30 | 2016-01-07 | Pfizer Inc. | Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer |
| AU2017219846B2 (en) * | 2016-02-19 | 2021-05-13 | Sprint Bioscience Ab | 6-aryl-4-morpholin-1-ylpyridone compounds useful for the treatment of cancer and diabetes |
| DK3416957T3 (da) | 2016-02-19 | 2020-09-21 | Sprint Bioscience Ab | 6-heterocyclyl-4-morpholin-4-ylpyridin-2-on-forbindelser anvendelige ved behandlingen af cancer og diabetes |
| CN111094271B (zh) * | 2017-08-23 | 2023-02-28 | 思普瑞特生物科学公司 | 吡啶胺-吡啶酮化合物和嘧啶胺-吡啶酮化合物 |
-
2018
- 2018-08-23 CN CN201880060298.1A patent/CN111094271B/zh active Active
- 2018-08-23 ES ES18759610T patent/ES2929424T3/es active Active
- 2018-08-23 FI FIEP18759610.1T patent/FI3672948T3/fi active
- 2018-08-23 IL IL292488A patent/IL292488B2/en unknown
- 2018-08-23 EP EP22199439.5A patent/EP4169581A1/en not_active Withdrawn
- 2018-08-23 CN CN202310112015.6A patent/CN116041320A/zh active Pending
- 2018-08-23 RS RS20221114A patent/RS63795B1/sr unknown
- 2018-08-23 SI SI201830781T patent/SI3672948T1/sl unknown
- 2018-08-23 SM SM20220493T patent/SMT202200493T1/it unknown
- 2018-08-23 DK DK18759610.1T patent/DK3672948T3/da active
- 2018-08-23 HR HRP20221454TT patent/HRP20221454T1/hr unknown
- 2018-08-23 PT PT187596101T patent/PT3672948T/pt unknown
- 2018-08-23 WO PCT/EP2018/072790 patent/WO2019038389A1/en not_active Ceased
- 2018-08-23 HU HUE18759610A patent/HUE060805T2/hu unknown
- 2018-08-23 IL IL302293A patent/IL302293A/en unknown
- 2018-08-23 PL PL18759610.1T patent/PL3672948T3/pl unknown
- 2018-08-23 US US16/639,900 patent/US11208423B2/en active Active
- 2018-08-23 AU AU2018320418A patent/AU2018320418B2/en not_active Ceased
- 2018-08-23 EP EP18759610.1A patent/EP3672948B1/en active Active
- 2018-08-23 TW TW111140666A patent/TW202325302A/zh unknown
- 2018-08-23 KR KR1020207007544A patent/KR102730753B1/ko active Active
- 2018-08-23 CN CN202310137693.8A patent/CN116041321A/zh active Pending
- 2018-08-23 LT LTEPPCT/EP2018/072790T patent/LT3672948T/lt unknown
- 2018-08-23 JP JP2020510114A patent/JP7201260B2/ja active Active
- 2018-08-23 TW TW107129494A patent/TWI785102B/zh not_active IP Right Cessation
-
2020
- 2020-02-20 IL IL272808A patent/IL272808B/en unknown
-
2021
- 2021-11-18 US US17/530,119 patent/US11780858B2/en active Active
-
2022
- 2022-12-14 JP JP2022199375A patent/JP2023021316A/ja not_active Ceased
- 2022-12-29 CY CY20221100816T patent/CY1125728T1/el unknown
-
2023
- 2023-07-06 AU AU2023204378A patent/AU2023204378A1/en not_active Abandoned
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