JP2023016083A - Cosmetic or topical skin preparation containing 3-o-ethyl ascorbic acid - Google Patents

Abstract

To provide a thickener that can be used for a cosmetic or a topical skin preparation containing 3-O-ethyl ascorbic acid in a wide pH region including an acidic region, the thickener being superior in all of thickening effect, viscosity stability, and usability.SOLUTION: A cellulose nanofiber having an anionic functional group is used as a thickener. This invention can provide a cosmetic or a topical skin preparation containing 3-O-ethyl ascorbic acid that satisfies all of thickening effect, viscosity stability, and usability.SELECTED DRAWING: None

Description

TECHNICAL FIELD The present invention relates to cosmetics or external preparations for skin containing 3-O-ethylascorbic acid.

3-O-ethylascorbic acid is widely used as an active ingredient in cosmetics and external preparations for skin as one of ascorbic acid derivatives with improved stability of ascorbic acid. 3-O-ethylascorbic acid, like ascorbic acid, has various physiologically active actions such as antioxidant, whitening, promotion of collagen production, promotion of hyaluronic acid production, scavenging of intracellular active oxygen, suppression of carbonyl protein, and anti-blue light. , is known to have effects such as moisturizing.

In cosmetics and external preparations for skin, it is common practice to impart appropriate viscosity to preparations for the purpose of enhancing usability such as ease of application and ease of removal from containers. Thickeners used in cosmetics and topical skin preparations include synthetic polymer-based thickeners such as carboxyvinyl polymers and alkyl acrylate/methacrylate polymers, as well as xanthan gum and hydroxyethyl cellulose. polysaccharide-based thickeners are known. However, when 3-O-ethylascorbic acid is blended, there are problems that a sufficient thickening effect cannot be obtained with a general thickening agent, the viscosity decreases over time, and the feeling of use is bad. rice field. In addition, as described in Patent Document 1, 3-O-ethylascorbic acid is known to have improved stability in the acidic pH range, and preparations containing 3-O-ethylascorbic acid As a thickening agent used in the above, one that can be used in a wide pH range including an acidic range is desired.

As a solution to the above problems, Patent Document 2 proposes a thickener having a sulfate ester group or a sulfonic acid group in the molecule, or a thickener having a hydrophobic group without a carboxyl group in the molecule. However, the thickening effect and the feeling of use were not always sufficient.

JP 2013-227264 A JP 2010-070492

An object of the present invention is to provide a cosmetic composition or external skin preparation containing 3-O-ethylascorbic acid with a thickening effect, viscosity stability, and a feeling of use that can be used in a wide pH range including an acidic range. To provide an excellent thickener for all of

As a result of intensive studies aimed at solving the above problems, the present inventors found that the above problems can be solved by using cellulose nanofibers having an anionic functional group as a thickening agent, and have completed the present invention. completed.

INDUSTRIAL APPLICABILITY According to the present invention, it is possible to obtain a 3-O-ethylascorbic acid-containing cosmetic or topical skin preparation that satisfies all of the thickening effect, viscosity stability, and feeling of use.

The cellulose nanofiber having an anionic functional group, which is the component (A) used in the present invention, is obtained by chemically introducing an anionic functional group into cellulose extracted from a plant cell wall or the like, followed by fibrillation. It is a fine cellulose fiber that has been miniaturized to the nano level. Cellulose, which is a raw material for the cellulose nanofibers having an anionic functional group of the present invention, includes wood pulp obtained from coniferous trees, broad-leaved trees, etc.; Wood pulp, cellulose isolated from sea squirts, cellulose isolated from seaweed, and the like can be used. The method for producing the cellulose nanofibers having an anionic functional group of the present invention is not particularly limited, and those produced by known chemical treatment and fibrillation treatment can be used.

As for the fiber diameter of the cellulose nanofiber having an anionic functional group of the present invention, the number average fiber diameter is 2 to 150 nm, preferably 2 to 100 nm. Although the aspect ratio (fiber length/fiber diameter) is not particularly limited, it should be 20 to 10,000 on average, preferably 50 to 2,000. The fiber length and fiber diameter can be determined by image analysis using AFM, TEM, SEM, or the like.

Specific examples of the anionic functional group to be introduced into the cellulose nanofibers of the present invention include a carboxy group, a phosphoric acid group, and a sulfone group. These anionic functional group-introduced cellulose nanofibers are also called carboxylated cellulose nanofibers, phosphate esterified cellulose nanofibers, and sulfonated cellulose nanofibers. As the cellulose nanofibers having anionic functional groups used in the present invention, commercially available products can be preferably used. Specifically, carboxylated cellulose nanofibers include Rheocrysta C-2PS (manufactured by Daiichi Kogyo Seiyaku Co., Ltd.), Celenpia TC-01A (manufactured by Nippon Paper Industries), and Celenpia CS-01C (manufactured by Nippon Paper Industries); As the esterified cellulose nanofiber, Auro Visco CS (manufactured by Oji Holdings Co., Ltd.); and as the sulfonated cellulose nanofiber, Stellafine (manufactured by Marusumi Paper Co., Ltd.) can be used.

The amount of component (A) to be added to the cosmetic composition or external preparation for skin of the present invention may be appropriately adjusted so as to obtain desired properties, and is not particularly limited, but is generally 0.01 to 5 masses. %, preferably 0.05 to 3 mass %.

3-O-ethylascorbic acid, the component (B) used in the present invention, is an ascorbic acid derivative obtained by ethyl-etherifying the hydroxyl group at the 3-position of ascorbic acid. The method for producing 3-O-ethylascorbic acid is not particularly limited, and one produced by a known method can be used. As a commercial product, Nippon Fine Chemical Co., Ltd. sells VC Ethyl (trade name), and such a commercial product can be preferably used.

The amount of component (B) to be blended in the cosmetic or topical skin preparation of the present invention is not particularly limited, but is 0.01 to 2% by mass, preferably 0.05 to 1% by mass.

In order to further improve the stability of 3-O-ethylascorbic acid, the cosmetic or topical skin preparation of the present invention preferably has a pH of 3 to 6, preferably 3.5 to 5.5. Adjustment of pH can be carried out according to a conventional method using an acid, an alkali, a pH adjuster, or the like.

Despite containing 3-O-ethylascorbic acid, the cosmetic or topical skin preparation of the present invention can be thickened by the component (A) in a wide pH range including an acidic range, and therefore has desired properties. can be adjusted. In addition, the decrease in viscosity over time is small, and the feeling of use is also excellent. From the viewpoint of exhibiting such effects more, component (A) is more preferably selected from carboxylated cellulose nanofibers and phosphate esterified cellulose nanofibers. Furthermore, phosphate-esterified cellulose nanofibers are most preferred from the viewpoint of transparency of formulations and stability of 3-O-ethylascorbic acid.

For the purpose of improving the stability of 3-O-ethylascorbic acid, the cosmetic or topical skin preparation of the present invention further contains a monohydric alcohol having 1 to 3 carbon atoms and a polyhydric alcohol as component (C). It is preferable to contain one or more selected from. Specific examples of monohydric alcohols having 1 to 3 carbon atoms include methanol, ethanol, propanol, isopropyl alcohol and the like. Specific examples of polyhydric alcohols include ethylene glycol, propylene glycol, 1,3-propanediol, 1,2-butylene glycol, 1,3-butylene glycol, 2,3-butylene glycol, 2-methyl -1,3-propanediol, 3-methyl-1,3-butanediol (isopentyldiol), tetramethylene glycol, hexylene glycol, caprylyl glycol, 1,2-pentanediol (pentylene glycol), 1, dihydric alcohols such as 2-hexanediol, 1,2-heptanediol, 1,2-octanediol and 1,2-decanediol; trihydric alcohols such as glycerin, trimethylolpropane and 1,2,6-hexanetriol; hydric alcohols; sugar alcohols such as sorbitol, xylitol, erythritol, maltitol, mannitol, and pentaerythritol; glyceryl ethers such as ethylglycerin, butylglycerin, hexylglycerin, and ethylhexylglycerin; diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol , polyhydric alcohol polymers such as dipropylene glycol, tripropylene glycol, polypropylene glycol, diglycerin, triglycerin, tetraglycerin, and polyglycerin. These may be used alone or in combination of two or more. Among these, from the viewpoint of stability of 3-O-ethylascorbic acid, ethanol, propylene glycol, 1,3-propanediol, 1,3-butylene glycol, 1,2-pentanediol, glycerin, dipropylene glycol, Diglycerin and the like are preferred, and ethanol, 1,3-butylene glycol and dipropylene glycol are more preferred. The amount of component (C) to be added to the cosmetic composition or external skin preparation of the present invention is not particularly limited, but from the viewpoint of the stability of 3-O-ethylascorbic acid, it is 1 to 50% by mass, preferably 3% by mass. ~30% by mass.

For the purpose of improving the stability of 3-O-ethylascorbic acid, it is preferable that the cosmetic or topical skin preparation of the present invention further contain a chelating agent as component (D). Chelating agents include edetic acid (ethylenediaminetetraacetic acid), hydroxyethylethylenediaminetriacetic acid, pentetic acid (diethylenetriaminepentaacetic acid), phytic acid, etidronic acid (hydroxyethanediphosphonic acid), citric acid, gluconic acid, succinic acid, and tartaric acid. , polyaspartic acid, polyglutamic acid, polyphosphoric acid, metaphosphoric acid, phosphoric acid and salts thereof. Among these, edetic acid, hydroxyethylethylenediaminetriacetic acid, pentetic acid, etidronic acid, citric acid and salts thereof are more preferred. The amount of component (D) to be added to the cosmetic composition or external skin preparation of the present invention is not particularly limited, but from the viewpoint of the stability of 3-O-ethylascorbic acid, it is preferably 0.01 to 5% by mass. is 0.05 to 2% by mass.

The cosmetic or topical skin preparation of the present invention may optionally contain water and additive components usually blended in cosmetics, such as oily bases, moisturizers/texture improvers, surfactants, polymers/thickeners/thickeners. Gelling agents, antioxidants, reducing agents, oxidizing agents, antioxidants, whitening agents, vitamins and their derivatives, plant/animal/microbe extracts, UV absorbers, antibacterial/preservatives, pH adjusters/acids・Alkali, solvent/propellant, antipruritic agent, exfoliating/dissolving agent, antiperspirant, cooling agent, astringent, enzymes, nucleic acids, anti-inflammatory agent/anti-inflammatory agent, hair growth agent/blood circulation promoter/irritant agents, hormones, anti-wrinkle/anti-aging agents, stimulant-relieving agents, cooling agents, warming agents, powders, dyes/colorants/dyes/pigments, fragrances, etc., to the extent that they do not impair the effects of the present invention. You may have

Oily bases include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, arachyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, cerachyl alcohol, batyl alcohol, hexyldecanol, isostearyl alcohol, 2-octyldodecanol, higher alcohols such as dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylenic acid, 12-hydroxystearic acid, palmitoleic acid, oleic acid, linoleic acid, linoleic acid, erucic acid, docosahexaenoic acid, eicosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acids, long-chain α-hydroxy fatty acids, dimer acid, Higher fatty acids such as hydrogenated dimer acid, metallic soaps such as aluminum salts, calcium salts, magnesium salts, zinc salts, potassium salts, sodium salts thereof, and nitrogen-containing derivatives such as amides; Hydrocarbons such as light liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene, vaseline, solid paraffin; candelilla wax, carnauba wax, rice wax, Waxes such as Japan wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax, petrolatum, Fischer-Tropsch wax, polyethylene wax, ethylene-propylene copolymer; coconut oil, palm oil, palm kernel oil, safflower oil , olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadowfoam oil, persic oil, tea tree oil, peppermint oil, corn oil, Plants such as rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil, peanut oil, rice bran oil, cocoa butter, shea butter, hydrogenated coconut oil, hydrogenated castor oil, jojoba oil, and hydrogenated jojoba oil Oils and fats; Animal fats and oils such as beef tallow, milk fat, horse fat, egg yolk oil, mink oil, and turtle oil; Animal waxes such as whale wax, lanolin, and orange roughy oil ; Liquid lanolin, reduced lanolin, adsorbed purified lanolin, lanolin acetate, liquid lanolin acetate, hydroxyl lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin acetate alcohol, lanolin such as acetic acid (cetyl/lanolyl) ester Phospholipids such as lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin and other sphingolipids, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof, and lysolecithin; , partially hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids and other phospholipid derivatives; cholesterol, dihydrocholesterol, lanosterol, dihydrolanosterol, phytosterol, sterols such as cholic acid; sapogenins; Cholesteryl acetate, cholesteryl nonanoate, cholesteryl stearate, cholesteryl isostearate, cholesteryl oleate, di(cholesteryl/behenyl/octyldodecyl) N-lauroyl-L-glutamate, di(cholesteryl/octyl N-lauroyl-L-glutamate) dodecyl), N-lauroyl-L-glutamic acid di(phytosteryl/behenyl/octyldodecyl), N-lauroyl-L-glutamic acid di(phytosteryl/octyldodecyl), N-lauroylsarcosine alkyl esters such as isopropyl, 12-hydroxy Cholesteryl stearate, macadamia nut oil fatty acid cholesteryl, macadamia nut oil fatty acid phytosteryl, sunflower seed oil fatty acid phytosteryl, phytosteryl isostearate, soft lanolin fatty acid cholesteryl, hard lanolin fatty acid cholesteryl, long-chain branched fatty acid cholesteryl, long-chain α-hydroxy fatty acid cholesteryl, etc. Esters; lipid complexes such as phospholipid/cholesterol complexes and phospholipid/phytosterol complexes; Hexyldecyl octanoate, isotridecyl isononanoate, isononyl isononanoate, octyl isononanoate, isotridecyl isononanoate, ne Isodecyl openpentanoate, isotridecyl neopentanoate, isostearyl neopentanoate, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl lanolin fatty acid, dicaprylyl carbonate, hexyldecyl dimethyloctanoate, octyldodecyl erucate , isostearic acid hydrogenated castor oil, ethyl oleate, avocado oil fatty acid ethyl, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, isopropyl lanolin fatty acid, methylheptyl laurate, methylheptyl myristate, methylheptyl palmitate , methylheptyl isostearate, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl succinate, monoalcohol carboxylic acid esters such as triethyl citrate; cetyl lactate, Hydrogenated castor oil monoisostearate, γ-erucalactone, oxyesters such as diisostearyl malate; glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, tri(caprylic acid/capric acid) ) glyceryl, tri (caprylic/capric/myristate/stearate) glyceryl, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), eicosane diacid glyceryl behenate, trimethylolpropane trioctanoate, Trimethylolpropane triisostearate, neopentyl glycol dioctoate, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol dioctoate, propylene glycol dioleate, pentaerythrityl tetraoctanoate, hydrogenation Rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, (isostearate/sebacate) ditrimethylolpropane, pentaerythrityl triethylhexanoate, (hydroxystearate/stearate/rosinate) dipentaerythrityl, diglyceryl diisostearate, tetraisostearin Polyglyceryl Acid, Polyglyceryl-10 Nonisostearate, Deca (Erucic Acid/Isostearic Acid/Ricinolei acid) polyglyceryl-8, (hexyldecanoic acid/sebacic acid) diglyceryl oligoester, glycol distearate (ethylene glycol distearate), 3-methyl-1,5-pentanediol dineopentanoate, 2,4-diethyl dineopentanoate polyhydric alcohol fatty acid esters such as 1,5-pentanediol; alkyl ethers such as dicaprylyl ether; diisopropyl dimer dilinoleate, diisostearyl dimer dilinoleate, di(isostearyl/phytosteryl) dimer dilinoleate, Dimer dilinoleic acid (phytosteryl/behenyl), dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl), dimer dilinoleyl dimer dilinoleate, dimer dilinoleyl diisostearate, dimer dilinoleyl hydrogenated rosin Derivatives of dimer acids or dimer diols such as condensates, dimer dilinoleic acid hydrogenated castor oil, hydroxyalkyl dimer dilinoleyl ethers; coconut fatty acid monoethanolamide (cocamide MEA), coconut fatty acid diethanolamide (cocamide DEA), laurin Acid Monoethanolamide (Lauramide MEA), Lauric Acid Diethanolamide (Lauramide DEA), Lauric Acid Monoisopropanolamide (Lauramide MIPA), Palmitic Acid Monoethanolamide (Palmitamid MEA), Palmitic Acid Diethanolamide (Palmitamic DEA), Coconut Fatty Acid Fatty acid alkanolamides such as methylethanolamide (cocamide methyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopentasiloxane), phenyltrimethicone, Diphenyl dimethicone, phenyl dimethicone, (aminoethylaminopropylmethicone/dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicone such as aminopropyl dimethicone and amodimethicone, cation-modified silicone, dimethicone copolyol, etc. Polyether-modified silicone, polyglycerin-modified silicone, sugar-modified silicone, carboxylic acid-modified silicone, phosphoric acid-modified silicone, sulfuric acid-modified silicone, alkyl-modified silicone, fatty acid-modified silicone, aluminum Kill ether-modified silicone, amino acid-modified silicone, peptide-modified silicone, fluorine-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone, alkyl-modified and polyether-modified silicone, amidoalkyl-modified silicone, aminoglycol-modified silicone , aminophenyl-modified silicones, polysiloxane-oxyalkylene copolymers, and other silicones; perfluorodecane, perfluorooctane, perfluoropolyether, and other fluorine-based oils are preferred.

Moisturizers and texture improvers include glycol alkyl ethers such as diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, and diethylene glycol dibutyl ether; (eicosanedioic acid/tetradecanedioic acid) polyglyceryl water-soluble esters such as -10, polyglyceryl-10 tetradecanedioate, bisethoxydiglycol cyclohexanedicarboxylate; glucose, fructose, galactose, mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose , raffinose, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrins and modified cyclodextrins such as maltosylation and hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, Arabinogalactan, dextrin, dextran, glycogen, ethyl glucoside, saccharides such as glucosylethyl methacrylate polymer or copolymer and derivatives thereof; hyaluronic acid, sodium hyaluronate; sodium chondroitin sulfate; mucoitin sulfate, caronin sulfate, keratosulfate , dermatan sulfate; white fungus extract, white fungus polysaccharide; fructans such as inulin and levan; fucoidan; tuberose polysaccharide, naturally occurring polysaccharide; -5-carboxylic acid and salts thereof such as sodium; betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, asparagine, asparagine Amino acids such as acid, cysteine, cystine, methionine, leucine, isoleucine, valine, tryptophan, histidine, taurine, γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid, carnitine, carnosine, creatine, and salts thereof; collagen, fish Derived Collagen, Atelocollagen, Gelatin, Elastin, Collagen Degradation Peptide, Hydrolyzed Collagen, Hydroxypropylammonium Chloride Hydrolyzed Collagen, Elastin Degradation Peptide, Keratin Degradation Peptide, Hydrolyzed Keratin, Conchiolin Degradation Peptide, Hydrolyzed Protein peptides such as conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soybean proteolytic peptide, wheat proteolytic peptide, hydrolyzed wheat protein, casein-degrading peptide, acylated peptide, and derivatives thereof; palmitoyl oligo Acylated peptides such as peptides, palmitoyl pentapeptides, and palmitoyl tetrapeptides; silylated peptides; lactic acid bacteria culture medium, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycosides, glutathione, albumin, Whey; choline chloride, phosphoryl choline; placental extract, aerastin, collagen, aloe extract, hamamelis water, luffa water, chamomilla extract, licorice extract, comfrey extract, silk extract, rose rose extract, yarrow extract, eucalyptus extract, melilot Animal/plant extracts such as extracts, natural ceramides (types 1, 2, 3, 4, 5, 6), ceramides such as hydroxyceramides, pseudoceramides, glycosphingolipids, ceramides, and sugar-ceramide-containing extracts are preferred. It is mentioned as.

Preferred surfactants include anionic surfactants, nonionic surfactants, cationic surfactants, amphoteric surfactants, polymeric surfactants, and the like. There is no particular limitation on the HLB of the surfactant, and a surfactant with a low HLB of about 1 to a surfactant with a high HLB of about 20 can be used, and a combination of a low HLB and a high HLB is also preferred. Examples of preferred surfactants include anionic surfactants such as fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfate salts such as sodium lauryl sulfate, triethanolamine lauryl sulfate and ammonium lauryl sulfate; Sodium sulfate, polyoxyethylene alkyl sulfates such as triethanolamine laureth sulfate; sodium cocoyl methyl taurate, potassium cocoyl methyl taurate, sodium lauroyl methyl taurate, sodium myristoyl methyl taurate, sodium lauroyl methyl alanine, sodium lauroyl sarcosine, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines, sodium methylalanine lauroyl glutamate; sodium cocoyl glutamate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoyl alanine triethanolamine , acyl amino acid salts such as dilauroyl glutamic acid lysine Na; polyoxyethylene alkyl ether acetate salts such as sodium laureth acetate; succinate ester salts such as lauroyl monoethanolamide sodium succinate; fatty acid alkanolamide ether carboxylate; fatty acid alkanolamide sulfates; fatty acid glyceride sulfates such as hydrogenated coconut oil fatty acid sodium glycerol sulfate; alkylbenzene polyoxyethylene sulfates; olefin sulfonates such as sodium α-olefin sulfonate; Alkyl sulfosuccinates such as disodium lauryl acid and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate, monolauroyl monoethanolamide sodium polyoxyethylene sulfosuccinate, and alkyl ether sulfosuccinates such as sodium lauryl polypropylene glycol sulfosuccinate; tetradecyl Alkylbenzenesulfonates such as sodium benzenesulfonate, triethanolamine tetradecylbenzenesulfonate; alkylnaphthalenesulfonates; alkanesulfonates; α-sulfo fatty acid methyl ester salts; acyl isethionates; Alkyl sulfoacetates; Alkyl ether phosphate salts such as sodium laureth phosphate, sodium dilaureth phosphate, sodium trilaureth phosphate and sodium monooleth phosphate; Alkyl phosphate salts such as potassium lauryl phosphate; Sodium caseinate; Phosphates; Fatty acid amide ether phosphates; Phospholipids such as phosphatidylglycerol, phosphatidylinositol, phosphatidic acid, cyclic lysophosphatidic acid or salts thereof; Anionic surfactants, etc.; nonionic surfactants include laureth (polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), beheneth (polyoxy ethylene behenyl ether), isosteareth (polyoxyethylene isostearyl ether), octyldodeceth (polyoxyethylene octyldodecyl ether), and other polyoxyethylene alkyl ethers of various polyoxyethylene addition numbers; polyoxyethylene alkylphenyl ethers; Polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, poly Castor oil and hydrogenated castor oil derivatives such as oxyethylene hydrogenated castor oil maleic acid; Polyoxyethylene phytosterol; Polyoxyethylene cholesterol; Polyoxyethylene cholestanol; Polyoxyethylene lanolin; Polyoxyethylene reduced lanolin; Propylene cetyl ether, polyoxyethylene/polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene/polyoxypropylene monobutyl ether, polyoxyethylene/polyoxypropylene hydrogenated lanolin, polyoxyethylene/polyoxypropylene glycerin ether, etc. Polyoxyethylene/polyoxypropylene alkyl ether; Polyoxyethylene/polyoxypropylene glycol; (poly)glycerin polyoxypropylene glycol such as PPG-9 diglyceryl; glyceryl stearate Ceryl, Glyceryl Isostearate, Glyceryl Palmitate, Glyceryl Myristate, Glyceryl Oleate, Glyceryl Cocoate, Monocottonseed Glycerol, Glyceryl Monoerucate, Glyceryl Sesquioleate, α,α'-Glyceryl Pyroglutamate Oleate, Monostearin Glycerin fatty acid partial esters such as acid glycerin malic acid; 2, polyglyceryl-10 destearate, polyglyceryl-2 isostearate, 3, 4, 5, 6, 8, 10, polyglyceryl-2 diisostearate (diglyceryl diisostearate), 3, 10 , polyglyceryl-2 triisostearate, polyglyceryl-2 tetraisostearate, polyglyceryl-10 decaisostearate, polyglyceryl-oleate-2, 3, 4, 5, 6, 8, 10, polyglyceryl dioleate- 6, polyglycerol fatty acid esters such as polyglyceryl-2 trioleate and polyglyceryl-10 decaoleate; ethylene glycol mono fatty acid esters such as ethylene glycol monostearate; propylene glycol mono fatty acid esters such as propylene glycol monostearate; pentaerythritol moieties Fatty acid ester; sorbitol partial fatty acid ester; maltitol partial fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan sesquioleate, sorbitan Sorbitan fatty acid esters such as trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; sucrose fatty acid esters, methylglucoside fatty acid esters, sugar derivative partial esters such as trehalose undecylenate; caprylyl Alkyl glucosides such as glucoside; Alkyl polyglycosides; Glycolipids such as mannosylerythritol lipids; Lanolin alcohol; Reduced lanolin; Olei Polyoxyethylene fatty acid mono- and diesters such as polyoxyethylene propylene glycol fatty acid esters; Polyoxyethylenes such as polyoxyethylene glycerin monostearate, polyoxyethylene glycerin monoisostearate, and polyoxyethylene glycerin triisostearate Polyoxyethylene glycerin fatty acid esters such as monooleate; Polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate ; polyoxyethylene sorbitol fatty acid esters such as polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol pentaoleate, polyoxyethylene sorbitol monostearate; polyoxyethylene methyl glucoside fatty acid ester; Oxyethylene alkyl ether fatty acid esters; Polyoxyethylene animal and vegetable oils and fats such as polyoxyethylene sorbitol beeswax; Alkyl glyceryl ethers such as isostearyl glyceryl ether, chimyl alcohol, selachyl alcohol and batyl alcohol; Oxyethylene alkylamine; tetrapolyoxyethylene/tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponin and sophorolipid; polyoxyethylene fatty acid amide; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil Fatty Acid Diethanolamide (Cocamide DEA), Lauric Acid Monoethanolamide (Lauramide MEA), Lauric Acid Diethanolamide (Lauramide DEA), Lauric Acid Monoisopropanolamide (Lauramide MIPA), Palmitic Acid Monoethanolamide (Partamide MEA), Palmitic Acid Diethanolamide fatty acid alkanolamides such as de (partamide DEA) and coconut oil fatty acid methylethanolamide (cocamide methyl MEA); alkyldimethylamine oxides such as lauramine oxide, cocamine oxide, stearamine oxide and behenamine oxide; alkylethoxydimethylamines oxide; polyoxyethylene alkyl mercaptan; polyether such as dimethicone copolyol; silicone-based nonionic surfactants such as ether-modified silicones, polysiloxane/oxyalkylene copolymers, polyglycerin-modified silicones, and sugar-modified silicones; cationic surfactants include behentrimonium chloride and steartrimonium chloride , cetrimonium chloride, lauryltrimonium chloride and the like; alkyltrimethylammonium bromide such as stearyltrimonium bromide; dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; Fatty acid amidoamines such as stearamidoethyldiethylamine and salts thereof; Alkyl ether amines such as stearoxypropyldimethylamine and salts or quaternary salts thereof; Long-chain branched fatty acids (12-31) aminopropylethyldimethylammonium ethyl sulfate, lanolin ethyl sulfate Fatty acid amide-type quaternary ammonium salts such as fatty acid aminopropylethyldimethylammonium; polyoxyethylene alkylamines and their salts or quaternary salts; alkylamine salts; fatty acid amide guanidinium salts; alkyl ether amine monium salts; ammonium salts; benzalkonium salts; benzethonium salts; pyridinium salts such as cetylpyridinium chloride; imidazolinium salts; silicone-based cationic surfactants such as modified silicone, cation-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone; fatty acid amide alkyl-N,N-dimethylamino acid betaines such as cocamidopropyl betaine and lauramidopropyl betaine; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; Alkylsulfobetaine such as dimethyltaurine; Sulfuric acid betaine such as alkyldimethylaminoethanol sulfate; Phosphate betaine such as alkyldimethylaminoethanol phosphate; Phospholipids such as lysolecithin, hydrogenated soybean phospholipids, partially hydrogenated soybean phospholipids, hydrogenated egg yolk phospholipids, partially hydrogenated egg yolk phospholipids, and hydroxylated lecithin; Silicone-based amphoteric surfactants, etc.; polymeric surfactants include polyvinyl alcohol, sodium alginate, starch derivatives, tragacanth gum, acrylic acid/methacrylate alkyl copolymers; and silicone-based various surfactants.

Polymers, thickeners and gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, gum arabic, tara gum, tamarind, furcelleran, karaya gum, tororo mallow, cara gum, tragacanth gum, pectin, pectic acid and sodium. Salts such as salts, salts such as alginic acid and sodium salts, mannan; starches such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salts, xanthan gum, pullulan, gellan gum, chitin , chitosan, agar, cassava extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose and salts thereof such as sodium, methylhydroxypropylcellulose, sodium cellulose sulfate, dialkyldimethyl Cellulose and its derivatives such as ammonium sulfate cellulose, crystalline cellulose, and cellulose powder; starch-based polymers such as soluble starch, carboxymethyl starch, methylhydroxypropyl starch, methyl starch, hydroxypropyltrimonium chloride starch, corn starch aluminum octenylsuccinate, etc. starch derivatives; sodium alginate, alginic acid derivatives such as propylene glycol alginate; Polyoxypropylene copolymer; Amphoteric methacrylic acid ester copolymer such as (methacryloyloxyethyl carboxybetaine/alkyl methacrylate) copolymer, (acrylates/stearyl acrylate/ethylamine methacrylate) copolymer; (dimethicone/vinyl dimethicone) cross Polymer, (alkyl acrylate/diacetone acrylamide) copolymer, (alkyl acrylate/diacetone acrylamide) copolymer AMP; partially saponified polyvinyl acetate, maleic acid copolymer; vinylpyrrolidone-dialkylaminoalkyl methacrylate copolymer; Acrylic resin alkanolamine; polyester, water-dispersible polyester; polya Crylamide; polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its salt such as sodium salt, acrylic acid/methacrylic acid ester copolymer; acrylic acid/alkyl methacrylate copolymer Polymer: cationized cellulose such as polyquaternium-10, diallyldimethylammonium chloride/acrylamide copolymer such as polyquaternium-7, acrylic acid/diallyldimethylammonium chloride copolymer such as polyquaternium-22, acrylic acid such as polyquaternium-39・Acrylic acid/methyl acrylate/chloride such as diallyldimethylammonium chloride/acrylamide copolymer, acrylic acid/cationized methacrylic acid ester copolymer, acrylic acid/cationized methacrylic acid amide copolymer, polyquaternium-47, etc. methacrylamidopropyltrimethylammonium copolymer, chloride methacrylic acid choline ester polymer; cationized polysaccharides such as cationized oligosaccharide, cationized dextran, guar hydroxypropyltrimonium chloride; polyethyleneimine; cationic polymer; Polymer of 2-methacryloyloxyethylphosphorylcholine and copolymer with butyl methacrylate copolymer; acrylic resin emulsion, polyethyl acrylate emulsion, polyacrylic alkyl ester emulsion, polyvinyl acetate resin emulsion, natural rubber latex, synthetic Polymer emulsions such as latex; nitrocellulose; polyurethanes and various copolymers; various silicones; acrylic-silicone graft copolymers and other silicone-based copolymers; salts thereof; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride, fumed silica (ultrafine anhydrous silicic acid), aluminum magnesium silicate, sodium magnesium silicate, metal soap, dialkyl phosphate metal salt, Bentonite, hectorite, organically modified clay minerals, sucrose fatty acid esters, and fructo-oligosaccharide fatty acid esters are preferred.

Antioxidants include tocopherol (vitamin E), tocopherol derivatives such as tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and/or derivatives thereof; erythorbic acid and derivatives thereof; sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfite; thiotaurine, hypotaurine; It is mentioned as. Preferred reducing agents include thioglycolic acid, cysteine, cysteamine, and the like. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate. Antioxidants include ascorbic acid, ascorbic acid phosphate salts such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; Ascorbic acid fatty acid esters such as palmitate and ascorbic acid tetraisopalmitate; ascorbic acid such as 3-O-ethylascorbic acid, 2-O-ethylascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, hexylglyceryl ascorbic acid Acid ethers; ascorbic acid glucosides such as ascorbic acid-2-glucoside and fatty acid esters thereof; ascorbic acid derivatives such as ascorbyl sulfate esters and tocopheryl ascorbyl phosphate; retinol, retinol acetate, retinol palmitate, hydrogenated retinol, etc. vitamin A; vitamin E such as tocopherol, tocopherol acetate, and tocotrienol; carotenoids such as carotene, lycopene, astaxanthin, and lutein; polyphenols; coenzyme Q10, lipoic acid, lactoferrin, sesamin, hesperidin, protoanthocyanidin, lignan, chlorogenic acid, rutin, fullerene, platinum nanocolloid and the like.

Whitening agents include hydroquinone glycosides such as arbutin and α-arbutin and their esters; ascorbic acid, ascorbic acid phosphate salts such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; ascorbic acid Ascorbic acid fatty acid esters such as monostearate, ascorbic acid monopalmitate, ascorbic acid dipalmitate, ascorbic acid tetraisopalmitate; 2-O-ethyl ascorbic acid, cetyl ascorbic acid, glyceryl ascorbic acid, ascorbic acid ethers such as hexylglyceryl ascorbic acid; ascorbic acid glucosides such as ascorbic acid-2-glucoside and fatty acid esters thereof; ascorbic acid derivatives such as ascorbyl sulfate and tocopheryl ascorbyl phosphate; tranexamic acid and cetyl tranexamic acid tranexamic acid derivatives such as tranexamic acid amide; licorice extract-related substances such as glabridin, glabren, liquiritin, isoliquiritin; kojic acid, ellagic acid, ferulic acid and derivatives thereof, placenta extract, glutathione, oryzanol, butylresorcinol, oil-soluble chamomilla extract , oil-soluble licorice extract, Nishikawayanagi extract, and saxifrage extract are preferred.

Examples of vitamins and derivatives thereof include vitamin A such as retinol, retinol acetate, and retinol palmitate; flavin adenine dinucleotide, cyanocobalamin, folic acids, nicotinic acids such as nicotinamide and benzyl nicotinate, B vitamins such as choline; vitamin Cs such as ascorbic acid and salts thereof such as sodium; vitamin D; Vitamin E such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphate salts such as ascorbyl phosphate sodium salt and ascorbyl phosphate magnesium salt, ascorbyl tetra Ascorbic acid fatty acid esters such as isopalmitate, ascorbyl stearate, ascorbyl palmitate, and ascorbyl dipalmitate, ascorbic acid alkyl ethers such as ascorbyl ethyl ether, ascorbic acid glucosides such as ascorbic acid-2-glucoside, and fatty acid esters thereof , ascorbic acid derivatives such as tocopheryl ascorbyl phosphate; vitamin derivatives such as tocopherol nicotinate, tocopheryl acetate, tocopherol linoleate, tocopherol ferulate, tocopherol phosphate, tocotrienols, and other various vitamin derivatives are preferred. It is mentioned as.

Plant/animal/microorganism extracts include iris extract, angelica keiskei extract, asunaro extract, asparagus extract, avocado extract, amacha extract, almond extract, altea extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, and ginkgo biloba extract. , inchkou extract, fennel extract, turmeric extract, oolong tea extract, urticaria extract, age extract, Echinashi leaf extract, trillium extract, Scutellaria root extract, Phellodendron bark extract, Coptis extract, Barley extract, Panax ginseng extract, Hypericum extract, Dead nettle extract, Ononis extract , Dutch mustard extract, orange extract, seawater dried matter, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolyzed silk, kakkon extract, chamomile extract, oil-soluble chamomile extract, carrot extract, wormwood extract, oat extract, karkade extract, licorice extract, oil-soluble licorice extract, kiwi extract, kiwi extract, cloud ear extract, cinchona extract, cucumber extract, paulownia leaf extract, guanosine, guava extract, kujin extract, gardenia extract, kumazasa extract, clara extract, walnut Extract, Chestnut extract, Grapefruit extract, Clematis extract, Black rice extract, Brown sugar extract, Black vinegar extract, Chlorella extract, Mulberry extract, Gentian extract, Gennoshoko extract, Black tea extract, Yeast extract, Koboku extract, Coffee extract, Burdock extract, Rice extract, Fermented rice extract, fermented rice bran extract, rice germ oil, comfrey extract, collagen, cowberry extract, rhinoceros extract, rhinoceros extract, rhinoceros extract, saffron extract, salvia extract, soapwort extract, bamboo grass extract, hawthorn extract, sansha extract, sunflower extract Shoyu extract, Shiitake extract, Rhododendron extract, Shikon extract, Perilla extract, Linden extract, Spiraea extract, Jatoba extract, Peony extract, Shokyu extract, Shobu root extract, White birch extract, White fungus extract, Horsetail extract, Stevia extract, Fermented stevia extract, Nishikawaryu extract , Ivy Extract, Hawthorn Extract, Sambucus Extract, Yarrow Extract, Mentha Extract, Sage Extract, Mallow Extract, Cnidium Extract, Assembly Extract, Sohakuhi Extract, Rhubarb Extract , soybean extract, turmeric extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, cinnamon extract, chimp extract, tea tree oil, sweet tea extract, capsicum extract, angelica extract, calendula officinalis extract, tonin extract, spruce extract, houttuynia cordata extract, Tomato extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, bakumondou extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, cypress extract, bisabolol, cypress extract, bifidobacterium extract , loquat extract, coltsfoot extract, coltsfoot extract, butterbur extract, bukuryo extract, butcher bloom extract, grape extract, grape seed extract, propolis, luffa extract, safflower extract, peppermint extract, bodaiju extract, button extract, hop extract, mica squid extract, pine extract, horse chestnut extract, skunk cabbage extract, soapberry extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, saxifrage extract, yuzu extract, lily extract, coix seed extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea Extracts such as lychee extract, lettuce extract, lemon extract, forsythia extract, astragalus extract, rose extract, rosemary extract, Roman chamomile extract, royal jelly extract, and burnet extract are preferred.

UV absorbers include para-aminobenzoic acid, para-aminobenzoic acid monoglycerol ester, N,N-dipropoxy para-aminobenzoic acid ethyl ester, N,N-diethoxy para-aminobenzoic acid ethyl ester, N,N-dimethyl para-aminobenzoic acid ethyl ester. Benzoic acid-based UV absorbers such as esters, N,N-dimethylpara-aminobenzoic acid butyl ester, N,N-dimethylpara-aminobenzoic acid ethyl ester; Anthranilic acid-based UV absorbers such as homomenthyl-N-acetylanthranilate; Salicylic acid and salicylic acid UV absorbers such as sodium salts thereof, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate; octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl -2,5-diisopropylcinnamate, ethyl-2,4-diisopropylcinnamate, methyl-2,4-diisopropylcinnamate, propyl-p-methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxy Cinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (cinoxate), cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenyl Cinnamic acid-based UV absorbers such as cinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxycinnamate, ferulic acid and derivatives thereof;2, 4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2'-dihydroxy-4,4'-dimethoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy- 4-methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4' -benzophenones such as phenyl-benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone UV absorber; 3-(4'-methylbenzylidene)-d,l-camphor, 3-benzylidene-d,l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5 -methylphenylbenzotriazole; 2-(2'-hydroxy-5'-t-octylphenyl)benzotriazole; 2-(2'-hydroxy-5'-methylphenylbenzotriazole; dibenzalazine; dianisoylmethane; 5-( 3,3-dimethyl-2-norbornylidene)-3-pentan-2-one; dibenzoylmethane derivatives such as 4-t-butylmethoxydibenzoylmethane; octyl triazone; urocanic acid and urocanic acid derivatives such as ethyl urocanate 2-(2′-hydroxy-5′-methylphenyl)benzotriazole, 1-(3,4-dimethoxyphenyl)-4,4-dimethyl-1,3-pentanedione, dimethoxybenzylidenedioxoimidazolidinepropionic acid Preferable examples include hydantoin derivatives such as 2-ethylhexyl, phenylbenzimidasozole sulfonic acid, terephthalylidene dicamfursulfonic acid, drometrizole trisiloxane, methyl anthranilate, rutin and its derivatives, oryzanol and its derivatives.

Antibacterial/antiseptic agents include parabens (hydroxybenzoic acid esters) such as methylparaben, ethylparaben, propylparaben, and butylparaben; phenoxyethanol; 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol 1,2-alkanediols such as; 2-ethylhexyl glyceryl ether (ethylhexylglycerin) and other alkyl glyceryl ethers; salicylic acid; lanolin fatty acid and salts thereof; sodium benzoate; Imidazolinone derivatives; imidazolinium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides, quaternary ammonium salts; Acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, hinokitiol; other phenols such as phenol, isopropylphenol, cresol, thymol, parachlorophenol, phenylphenol, phenylphenol sodium; phenylethyl alcohol, photosensitizers, antibacterial zeolites and silver ions are preferred, but when used as an antibacterial agent or antiseptic for the purpose of preserving, phenoxyethanol; 1,2-pentanediol; 1,2-pentanediol; 1,2-alkanediols such as 1,2-hexanediol and 1,2-octanediol; alkyl glyceryl ethers such as 2-ethylhexyl glyceryl ether are more preferably used.

pH adjusters, acids, and alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, and monoethanol. Amines, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxide Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferred.

Solvents/propellants include lower alcohols such as ethanol, 2-propanol (isopropyl alcohol), butanol and isobutyl alcohol; glycols such as propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol and isopentyldiol. Classes: Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether glycol ethers such as ethylene glycol monoethyl ether acetate, diethylene glycol monoethyl ether acetate and propylene glycol monoethyl ether acetate; glycol ether esters such as diethoxyethyl succinate and ethylene glycol disuccinate; benzyl Propellants such as alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate, acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbons, next-generation freon; LPG, dimethyl ether, and carbon dioxide are preferred.

Examples of antipruritic agents include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitors and the like. Examples of exfoliating/dissolving agents include salicylic acid, sulfur, resorcinol, selenium sulfide, pyridoxine, glycolic acid, and the like. Examples of antiperspirants include aluminum chlorohydroxy, aluminum chloride, zinc oxide, and zinc paraphenolsulfonate. Examples of cooling agents include menthol and methyl salicylate. Examples of astringents include citric acid, tartaric acid, lactic acid, aluminum/potassium sulfate, tannic acid, and caffeine. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease, and the like. Preferred nucleic acids include ribonucleic acid and its salts, deoxyribonucleic acid and its salts, and disodium adenosine triphosphate.

Antiphlogistic agents and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhizic acid derivatives, salicylic acid and its derivatives, azelaic acid and its derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, Chlorpheniramine maleate; plant extracts such as peach leaf extract and mugwort leaf extract are preferred. Hair growth agents, blood circulation promoters, and stimulants include plant extracts and tinctures such as assembly extract, capsicum tincture, ginger tincture, ginger extract, and cantharis tincture; , borneol, cyclanderate, cinnarizine, tolazoline, acetylcholine, verapamil, cepharanthine, γ-oryzanol, cepharanthine, vitamin E and derivatives such as tocopherol nicotinate and tocopherol acetate, γ-oryzanol, nicotinic acid and nicotinamide, benzyl nicotinate Derivatives such as ester-inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, flavanonol derivatives, stigmasterol or stigmastanol and its glycosides, and minoxidil are preferred. It is mentioned as. Preferred hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone, and the like.

Anti-wrinkle/anti-aging agents include ascorbic acid, ascorbic acid phosphate salts such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; ascorbic acid monostearate, ascorbic acid monopalmitate, Ascorbic acid fatty acid esters such as ascorbic acid dipalmitate and ascorbic acid tetraisopalmitate; Ascorbic acid glucoside such as acid-2-glucoside and fatty acid esters thereof; ascorbic acid sulfate ester, tocopheryl ascorbyl phosphate and other ascorbic acid derivatives; retinol, retinol acetate, retinol palmitate, hydrogenated retinol and other vitamin A groups; Nicotinamide, glutathione, cysteine, crocetin, sericin, geraniol, glycerin glucoside, lactoferrin, proanthocyanin, pantothenic acid, panthenol, soybean saponin, levelerol, isoflavone, coenzyme Q10, chondroitin sulfate, acetylglucosamine, glycerophosphatidylcholine , hydrolyzed hyaluronic acid, collagen peptide, conchiolin hydrolyzate, adenosine 5'-monophosphate, phosphatidylinositol, trifluoride isopropyloxopropylaminocarbonylpyrrolidinecarbonylmethylpropylaminocarbonylbenzoylaminoacetic acid Na, tranexamic acid and derivatives thereof, etc. It is mentioned as a preferable one.

Irritation-relieving agents include mannosylerythritol lipid, diethylene glycol oligomer dimer dilinoleate, diisostearyl malate, N-acyl-L-glutamic acid, trehalose monofatty acid ester, fatty acid amidoamine oxide, alkyldimethylamine oxide, phenylethyl glucoside, Lauryl glucoside, ferulic acid glucoside, salicin, cedrol, polyethylene glycol, polypropylene glycol and the like are preferred. Preferred cooling agents include menthol, camphor, menthyl lactate, monomenthyl succinate, menthyl acetate, borneol, cineol, thymol, peppermint oil, peppermint oil and derivatives thereof. Examples of warming agents include vanillin and its derivatives, nonanoic acid vanillylamide, shogaol, gingerol, capsicum tincture, capsicum extract, nicotinic acid derivatives such as benzyl nicotinate, methyl nicotinate, phenyl nicotinate, tocopherol nicotinate, capsaicin, and the Netherlands. Mustard extract, Japanese pepper extract, ginger extract, cantari extract and the like are preferred.

Powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluoroapatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (e.g. zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, red iron oxide, yellow iron oxide, black iron oxide, ultramarine blue, Prussian blue, carbon black, titanium oxide, fine and ultrafine titanium oxide, zinc oxide , fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silicic anhydride), mica titanium, fish scale foil, boron nitride, photochromic pigment, synthetic fluorine phlogopite, fine particle composite powder, gold, aluminum, etc. Inorganic powders of various sizes and shapes, and these are treated with various surface treatment agents such as silicone such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents to make them hydrophobic or Inorganic powder such as hydrophilized powder; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, styrene-acrylic acid copolymer resin powder, polyester powder, benzoguanamine resin powder, polyethylene terephthalate・Organic powders and surface-treated powders of various sizes and shapes, such as polymethyl methacrylate layered powder, polyethylene terephthalate/aluminum/epoxy layered powder, urethane powder, silicone powder, Teflon (registered trademark) powder, etc., organic and inorganic Composite powders are preferred. Examples of inorganic salts include sodium chloride-containing salts such as table salt, common salt, rock salt, sea salt, and natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum/potassium sulfate (alum), aluminum/ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na, and 3Na phosphate, phosphoric acid Potassiums, calcium phosphates, and magnesium phosphates are preferred.

Colorants/colorants/dyes/pigments include Brown No. 201, Black No. 401, Purple No. 201, Purple No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 202, Blue No. 203 and Blue No. 204. , Blue No. 205, Blue No. 403, Blue No. 404, Green No. 3, Green No. 201, Green No. 202, Green No. 204, Green No. 205, Green No. 3, Green No. 401, Green No. 402, Red No. 102, Red 104-1, red 105-1, red 106, red 2, red 3, red 201, red 202, red 203, red 204, red 205, red 206, red 207 , Red No. 208, Red No. 213, Red No. 214, Red No. 215, Red No. 218, Red No. 219, Red No. 220, Red No. 221, Red No. 223, Red No. 225, Red No. 226, Red No. 227, Red 228, Red 230-1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503 , Red No. 504, Red No. 505, Red No. 506, Orange No. 201, Orange No. 203, Orange No. 204, Orange No. 205, Orange No. 206, Orange No. 207, Orange No. 401, Orange No. 402, Orange No. 403, Yellow 201, yellow 202-1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404, yellow Legal dyes such as No. 405, Yellow No. 406, Yellow No. 407, and Yellow No. 5; Other acid dyes such as Acid Red 14; Basic dyes such as Arianor Sienna Brown, Arianor Madder Red, Arianor Steel Blue, and Arianor Straw Yellow; HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydroxypropylamino-3-nitrophenol, N,N'-bis(2-hydroxyethyl)-2-nitro-p-phenylenediamine, HC Blue 2, Basic Blue 26 and other nitro dyes; Disperse dyes; Inorganic white pigments such as titanium dioxide and zinc oxide; Inorganic red pigments such as iron oxide (red iron oxide) and iron titanate; Inorganic brown pigments such as γ-iron oxide; Inorganic yellow pigments such as yellow iron oxide and ocher Inorganic black pigments such as black iron oxide and low order titanium oxide; Inorganic pigments such as mango violet and cobalt violet Purple pigments; Inorganic green pigments such as chromium oxide, chromium hydroxide, and cobalt titanate; Inorganic blue pigments such as ultramarine blue and Prussian blue; Titanium oxide-coated mica, titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, colored oxide Pearl pigments such as titanium-coated mica, bismuth oxychloride, and fish scale foil; metal powder pigments such as aluminum powder, copper powder, and gold; Quercetin, crocin, chlorophyll, curcumin, cochineal, shikonin and other naphthoquinones, bixin, flavones, betacyanidin, henna, hemoglobin, lycopene, riboflavin, rutin and other natural pigments and dyes; p-phenylenediamine, toluene-2,5 - oxidation dye intermediates such as diamine, o-, m-, or p-aminophenol, m-phenylenediamine, 5-amino-2-methylphenol, resorcinol, 1-naphthol, 2,6-diaminopyridine, etc. and salts thereof autooxidative dyes such as indolines; and dihydroxyacetone are preferred.

Fragrances include acetylcedrene, amyl cinnamaldehyde, allyl amyl glycolate, β-ionone, iso-e-super, isobutylquinoline, iris oil, iron, indole, ylang-ylang oil, undecanal, undecenal, γ-undecenal, Estragole, eugenol, oakmoss, opoponax resinoid, orange oil, eugenol, aurantiol, galacsolid, carvacrol, L-carvone, camphor, cannon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile , isobornyl acetate, geranyl acetate, dimethylbenzyl carbyl acetate, styraryl acetate, cedryl acetate, terpinel acetate, p-t-butylcyclohexyl acetate, betiveryl acetate, benzyl acetate, linalyl acetate, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, Cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromyrcenol, jasmine absolute, jasmine lactone, cis-jasmone, citral, citronenol, citronellal, cinnamon bark oil, 1,8-cineol, cinnamaldehyde, styrax Resinoids, cedarwood oil, cedren, cedrol, celery seed oil, thyme oil, damascone, damascenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, tripral, nerol, nonanal, 2,6-nonadienol, nonalactone, patchouli Alcohol, vanilla absolute, vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitgrain oil, hexylcinnamaldehyde, cis-3-hexenol, peruvian balsam, vetiver oil, vetiverol , peppermint oil, pepper oil, heliotropine, bergamot oil, benzyl benzoate, borneol, myresinoid, musk ketone, methylnonylacetaldehyde, γ-methylionone, menthol, L-menthol, L-mentone, eucalyptus oil, β-ionone, lime oil , lavender oil, D-limonene, linalool, lilal, lilial, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils and other synthetic fragrances and natural Perfumes and various blended perfumes are preferred.

Preferable examples of water include ordinary water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionized water, and cluster water.

In addition to these, the Standards for Cosmetic Ingredients, Standards for Ingredients by Cosmetic Type, List of Ingredients Displayed by the Japan Cosmetic Industry Association, INCI Dictionary (The International Cosmetic Ingredient Dictionary and Handbook), Standards for Quasi-drug Ingredients, Japanese Pharmacopoeia, Pharmaceutical Additives Ingredients listed in standards, food additives compendium, etc., and in Japanese and foreign patent publications and patent publication publications (including publication publications and republication) that belong to the classification of A61K7 and A61K8 in the international patent classification IPC Known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as those described, can be contained in known combinations and blending ratios and blending amounts.

Types of the cosmetics of the present invention include hair cosmetics, skin cosmetics, make-up cosmetics, aromatic cosmetics, body cosmetics and the like. The cosmetic of the present invention can be produced according to ordinary methods.

To explain the types of the cosmetics of the present invention in more detail, hair cosmetics include shampoos such as oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, hair color shampoos, rinse-integrated shampoos; Hair care agents such as treatments, hair packs, hair mists, and hair oils; Hair foams, hair mousses, hair sprays, hair waxes, hair gels, hair creams, water greases, set lotions, pomades, ticks, and other hair styling agents; Color lotions, hair color treatments, Hair manicure, hair dye such as oxidation hair dye; hair tonic, hair liquid, hair blow, split ends coat, permanent wave agent, straight perm agent, hair bleach, hair color pre-treatment, hair color after-treatment, perm pre-treatment , perm after treatment, and hair growth agents are preferred.

Skin cosmetics include lotions such as softening lotion, astringent lotion, cleansing lotion, multi-layer type lotion, and liposome lotion; emollient lotion, moisturizing lotion, milky lotion, nourishing lotion, nourishing milk, skin Moisture, moisturizing emulsion, massage lotion, keratin smoother, elbow lotion, hand lotion, body lotion; emollient cream, nourishing cream, nourishing cream, vanishing cream, moisturizing cream, night cream, massage cream, cleansing cream, Creams such as make-up cream, base cream, pre-makeup cream, sunscreen cream, suntan cream, depilatory cream, deodorant cream, shaving cream, keratin softening cream; gels such as moisturizing gel, whitening gel, all-in-one gel; moisturizing essence , whitening essence, moisturizing serum, whitening serum; sunscreens such as sun protect, sun protector, UV care milk, sunscreen; packs and masks such as peel-off packs, powder packs, washing packs, oil packs, cleansing masks Types; cleansing foam, cleansing cream, cleansing milk, cleansing lotion, cleansing gel, cleansing oil, etc.; paste facial cleansing foam, gel facial cleansing foam, foaming facial cleansing foam, facial cleansing powder, cosmetic soap, transparent soap, medicated soap, liquid soap , facial cleansers such as shaving soap;

Preferred examples of makeup cosmetics include lipsticks, lip glosses, foundations, blushers, powders/powder powders, concealers, eyeliners, mascara, eyeshadows, eyebrows, eyebrows, nail enamels, enamel removers, and nail treatments.

Perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, paste perfume, fragrant powder, perfumed soap, body lotion, and bath oil are preferable examples of fragrant cosmetics.

Body cosmetics include body cleansers such as body shampoo, deodorant cosmetics such as deodorant lotions, deodorant powders, deodorant sprays, and deodorant sticks, decolorants, hair removal agents, bath agents, and insect repellent sprays. Repellers are preferred.

Preferred types of the external preparation for skin of the present invention include ointments, lotions, cream or gel-like external preparations, patches, liniments, liquid coatings, and the like. It can also be used as an oral cosmetic such as toothpaste and mouthwash.

Formulations of the cosmetic or external preparation for skin of the present invention include emulsions such as oil-in-water (O/W) type, water-in-oil (W/O) type, W/O/W type, and O/W/O type. type cosmetics, oil-based cosmetics, solid cosmetics, liquid cosmetics, paste-type cosmetics, stick-type cosmetics, volatile oil-type cosmetics, powder-type cosmetics, jelly-type cosmetics, gel-type cosmetics, paste-type cosmetics Preferable dosage forms include cosmetics, emulsified polymer type cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

The present invention will be described in more detail by the following examples, but the present invention is not limited to these.

Evaluation of Gel Cosmetics Gel cosmetics were prepared with the compositions shown in Tables 1 and 2 (Examples 1 and 2, Comparative Examples 1 to 7). The resulting gel cosmetics were evaluated for initial viscosity, viscosity stability (50° C./1 month), feeling during use, and 3-O-ethylascorbic acid residual rate (50° C./1 month). Evaluation methods are described below. The results are shown in Tables 1 and 2 together.

<Evaluation of viscosity stability>
The viscosity of the gel cosmetic was measured initially and after storage at 50°C/1 month, and the viscosity reduction rate after 50°C/1 month with respect to the initial viscosity (viscosity after 100-50°C/1 month/initial viscosity x 100 ) was calculated. The results were shown by the following criteria based on the calculated viscosity reduction rate. The viscosity was measured at 25° C. using a Brookfield viscometer (manufactured by Toki Sangyo Co., Ltd.).

Judgment criteria Viscosity reduction rate is less than 20%: ○
Viscosity reduction rate of 20% or more to less than 50%: △
Viscosity reduction rate is 50% or more: ×

<Method for evaluating usability>
Two items, sticky feeling at the time of application and dry feeling after drying, were evaluated according to the following evaluation criteria. The results were shown by the following criteria based on the average score of five panelists.

Evaluation Criteria <Smoothness at the time of application>
Not felt at all: 5 points Not felt much: 4 points Normal: 3 points Somewhat felt: 2 points Very felt: 1 point <Smooth feeling after drying>
Very much: 5 points Somewhat: 4 points Normal: 3 points Not very: 2 points Not at all: 1 point

Judgment criteria [Average score] : [Judgment]
4.5 or more: ◎
3.5 or more to less than 4.5: ○
1.5 or more to less than 3.5: △
Less than 1.5: ×

<Method for evaluating residual rate of 3-O-ethylascorbic acid>
HPLC (column: octadecylsilylated silica gel column, eluent: 0.01 M sodium dihydrogen phosphate aqueous solution/acetonitrile = 96/4, column temperature: 40 ° C., flow rate: 1 mL / min, detector: UV245 nm), 3-O-ethyl ascorbic acid residual rate after 50 ° C. / 1 month (50 ° C. / after 1 month content/initial content×100) was calculated.

From the results in Tables 1 and 2, Examples 1 and 2 using the component (A) of the present invention as a thickening agent satisfy all of the thickening effect, viscosity stability, and feel during use. None of Comparative Examples 1 to 7, which used other thickening agents, satisfied all requirements. In addition, compared to Example 2, Example 1 has a transparent appearance, a very high 3-O-ethylascorbic acid residual rate, and excellent stability of 3-O-ethylascorbic acid. From these results, it was found that phosphate-esterified cellulose nanofibers are more preferable as the component (A) of the present invention.

Example 3 Lotion
Ingredient Amount (% by mass)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Department A Auro Visco CS (Oji Holdings) 10.0
Tremoist-TP (Nippon Fine Chemicals) 0.1
Sodium hyaluronate 0.1
Purified water 20.0
Part B 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Nicotinamide 5.0
Ethanol 7.0
BG 7.0
Glycerin 5.0
Inulin-SC (Nippon Fine Chemical) 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Methylparaben 0.1
Phenoxyethanol 0.2
Citric acid 0.05
Na citrate Amount that pH becomes 4.5 Pentetate pentasodium 0.10
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was stirred to form a viscous liquid. Part B was heated to about 70° C. and dissolved uniformly. Part A was added to part B at about 50° C. and dissolved uniformly by stirring.

Example 4 Lotion Ingredients Amount (% by mass)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A PrimeLipid PI (Nippon Fine Chemicals) 0.25
BG 5.0
Dipropylene glycol 3.0
1,2-Pentanediol 3.0
Part B Nicotinamide 1.0
Tranexamic acid (Nippon Fine Chemicals) 1.0
Purified water 30.0
Department C Auro Visco CS (Oji Holdings) 10.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Neosolue-Aqua (Nippon Fine Chemicals) 1.0
Phytopresome MEL (Nippon Fine Chemicals) 0.2
Dipotassium glycyrrhizinate 0.1
Inulin-SC (Nippon Fine Chemicals) 0.1
Citric acid 0.1
Na citrate Amount that pH becomes 4.5 Pentetate pentasodium 0.05
Phytic acid 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount that totals 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of parts A and B was heated to 70° C., and part A was added while stirring part B with a homomixer (7000 rpm) to prepare a nanovesicle solution. After cooling, the pre-mixed part C was added to obtain a uniform liquid.

Example 5 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A BG 5.0
Inositol 0.5
Glycyrrhizinate 2K 0.01
Ethanol 3.0
Phenoxyethanol 0.2
Methylparaben 0.15
Citric acid 0.1
Na citrate Amount that makes the pH 4.5 Purified water Amount that makes the total 100 Part B Purified water 5.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Department C Auro Visco CS (Oji Holdings) 8.0
Carboxylated cellulose nanofiber (2% aqueous solution) 3.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 80° C. and dissolved uniformly. After cooling part A to 40° C., part B and part C were added to obtain a uniform liquid.

Example 6 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A BG 5.0
Neosolue-AquaS (Nippon Fine Chemicals) 1.5
Ethanol 3.0
Phenoxyethanol 0.2
Methylparaben 0.15
Citric acid Amount that makes pH 4.5 Na citrate 0.1
Purified water Amount to be 100 in total Part B Purified water 5.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Department C Auro Visco CS (Oji Holdings) 15.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 80° C. and dissolved uniformly. After cooling part A to 40° C., part B and part C were added to obtain a uniform liquid.

Example 7 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytopresome (Nippon Fine Chemicals) 0.2
BG 10.0
Part B Purified water 20.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 0.5
Succinic acid Appropriate amount Na succinate 0.1
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water 100 in total Part D Auro Visco CS (Oji Holdings) 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Mix part A and slowly add to part B with stirring. Further, pre-mixed parts C and D were added to obtain a uniform liquid.

Example 8 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytopresome MEL (Nippon Fine Chemicals) 3.0
DPG 3.0
Glycerin 1.0
Part B Purified water 20.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.7
Neosolue-Aqulio (Nippon Fine Chemicals) 0.5
Nicotinamide 0.3
Betaine 1.0
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water 100 in total Part D Auro Visco CS (Oji Holdings) 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Mix part A and slowly add to part B with stirring. Further, pre-mixed parts C and D were added to obtain a uniform liquid.

Example 9 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Diglycerin 3.0
Hydrolyzed hyaluronic acid 0.01
Arginine 0.05
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Betaine 0.5
Pullulan 0.5
Arginine 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount to be 100 in total Part B 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 1.0
Auro Visco CS (Oji Holdings) 4.0
Carboxylated cellulose nanofiber (2% aqueous solution) 4.0
Sodium hyaluronate 0.01
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was warmed to about 80° C. and mixed uniformly. Part B was added to make a uniform liquid.

Example 10 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Diglycerin 3.0
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
PEG/PPG/polybutylene glycol-8/5/3 glycerin 0.5
Glucosylceramide 0.5
Glucosylrutin 0.01
Polyquaternium-51 0.5
Acetyl hexapeptide-8 0.001
Hydrolyzed Collagen 0.05
Arginine 0.05
Phenoxyethanol 0.2
Methylparaben 0.15
Xanthan gum 0.1
Purified water Total amount to be 100 Part B 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.3
Auro Visco CS (Oji Holdings) 5.0
Tremoist-TP (Nippon Fine Chemicals) 0.01
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was warmed to about 80° C. and mixed uniformly. Part B was added to make a uniform liquid.

Example 11 Gel lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-PP (Nippon Fine Chemicals) 1.0
Glycerin 5.0
Sorbitol liquid (70%) 5.0
Glyceryl behenate 0.8
Stearic acid 0.3
PEG-10 dimethicone 0.4
Part B Phenoxyethanol 0.3
Pullulan 0.2
Ethylhexylglycerin 0.2
Poly HEMA glucoside 0.05
Polymethacryloyllysine 0.05
Crystalline cellulose powder 0.1
Locust bean gum 0.03
Sodium hyaluronate 0.01
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.05
Auro Visco CS (Oji Holdings) 40.0
Tremoist-TP (Nippon Fine Chemicals) 0.1
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 70°C and dispersed uniformly. Part B was mixed, stirred well, homogenized and heated to about 70°C. Part B was added to part A, the mixture was stirred at about 70°C using a homomixer, cooled to about 40°C, and part C was added.

Example 12 Gel lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-PP (Nippon Fine Chemicals) 0.5
Glycerin 5.0
Sorbitol liquid (70%) 5.0
Glyceryl behenate 0.8
Stearic acid 0.3
PEG-20 hydrogenated castor oil 0.1
Polyglyceryl-10 oleate 0.1
Part B Phenoxyethanol 0.3
Pullulan 0.2
Ethylhexylglycerin 0.2
Polymethacryloyllysine 0.05
Crystalline cellulose powder 0.1
Locust bean gum 0.03
Hydroxyethyl cellulose 0.05
Sodium hyaluronate 0.01
Carbomer 0.06
K hydroxide 0.05
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 25.0
Carboxylated cellulose nanofiber (2% aqueous solution) 25.0
Tremoist-TP (Nippon Fine Chemicals) 0.005
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 70°C and dispersed uniformly. Part B was mixed, stirred well, homogenized and heated to about 70°C. Part B was added to part A, stirred at about 70°C using a homomixer, and cooled to about 40°C. Add mixed Part C and mix evenly.

Example 13 Transparent gel
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 3.0
PEG-4000 0.2
Methylgluceth-10 1.0
Phenoxyethanol 0.3
Pyridoxine hydrochloride 0.05
Ethylhexylglycerin 0.2
Hydrolyzed Collagen 0.01
Purified water 100 in total Part B Auro Visco CS (Oji Holdings) 20.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.9
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was stirred to form a uniform liquid. The B part and the C part were added to the A part and made uniform.

Example 14 Emulsion
Ingredient Amount (% by mass)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Sorbitan stearate 0.5
PEG-10 stearate 0.5
Polysorbate 60 0.5
Neosolue-DiSM (Nippon Fine Chemicals) 1.0
Plandool-LG2 (Nippon Fine Chemicals) 1.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
Plandool-S (Nippon Fine Chemicals) 1.0
Squalane 3.0
Polyglyceryl-2 diisostearate 1.0
Jojoba oil 1.0
Ethylparaben 0.1
Part B Auro Visco CS (Oji Holdings) 10.0
(Ammonium acryloyldimethyltaurate/VP) copolymer 0.05
Purified water 20.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Tranexamic acid (Nippon Fine Chemicals) 1.0
BG 5.0
Dipropylene glycol 3.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Citric acid 0.07
Na citrate Amount that makes pH 5.0 Phytic acid 0.5
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 70° C. and dissolved uniformly. Part B was stirred to form a viscous liquid. Part C was heated to about 70° C. and dissolved uniformly. Add part C to part A, emulsify with a homomixer, cool, add part B at about 50° C., and stir to obtain a uniform liquid.

Example 15 Emulsion
Ingredient Amount (% by mass)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-C (Nippon Fine Chemicals) 1.0
BG 10.0
Glycerin 9.0
Part B Bisethylhexyloxyphenol methoxyphenyltriazine
1.0
Diethylaminohydroxybenzoyl hexyl benzoate 1.0
Ethylhexyl Triazone 1.0
Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 2.0
Diethylhexyl Sebacate (Nippon Fine Chemicals) 3.0
Diethyl Sebacate (Nippon Fine Chemicals) 3.0
Diisopropyl sebacate (Nippon Fine Chemicals) 6.0
behenyl alcohol 2.0
Plandool-LG3 (Nippon Fine Chemicals) 0.5
Plandool-SUN (Nippon Fine Chemicals) 0.5
Plandool-ISS (Nippon Fine Chemicals) 0.5
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Nicotinamide 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Citric acid 0.05
Na citrate Amount that pH becomes 5.0 Pentetate pentasodium 0.05
Methylparaben Appropriate amount Purified water Amount that makes the total 100 Part D Auro Visco CS (Oji Holdings) 10.0
Water-dispersed titanium oxide 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Disperse part A evenly. Part B and part C are heated to about 70° C. and melted. After gradually adding part B to part A, gradually add part C and emulsify. Cool while stirring, add part D at 45°C and stir.

Example 16 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Diisostearyl malate 5.0
Plandool-DP (Nippon Fine Chemicals) 1.0
Cetyl ethylhexanoate (Nippon Fine Chemicals) 10.0
Cetanol 1.2
Phenyltrimethicone 3.0
Ethylparaben 0.1
Myristyl alcohol 2.0
Oleyl alcohol 1.0
Part B Auro Visco CS (Oji Holdings) 25.0
Carboxylated cellulose nanofiber (2% aqueous solution) 10.0
Stealoxy hydroxypropyl methylcellulose 0.1
Xanthan gum 0.1
Purified water 20.0
Part C Phytocompo-PP (Nippon Fine Chemicals) 1.0
Pentylene glycol 3.0
Glycerin 8.0
Part D 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Purified water 20.0
Part E Phenoxyethanol 0.2
Methylparaben 0.15
Phytic acid 0.5
Succinic acid Appropriate amount Na succinate Appropriate amount Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－ --
(Preparation method)
Part A and part E were each heated to about 70° C. and dissolved uniformly. Part B was stirred to form a viscous liquid. Part C was heated to about 70° C. and evenly dispersed. After adding part A while stirring part C with a homodisper, part E was added while stirring. Part D and part B were added at about 50° C. and dissolved uniformly by stirring.

Example 17 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-C (Nippon Fine Chemicals) 1.0
Hydrogenated Lysolecithin (Nippon Fine Chemicals) 0.1
Part B Mineral oil 5.0
Triethylhexanoin (Nippon Fine Chemicals) 3.0
LUSPLAN SR-DM4 (Nippon Fine Chemical) 0.5
Hydrogenated polyisobutene 3.5
Isododecane 1.5
Cetostearyl alcohol 1.0
Arachyl alcohol 0.1
Jojoba Alcohol 3.0
chimyl alcohol 0.3
Serachyl alcohol 0.1
Hexyldecanol 0.5
Part C (Hydroxyethyl acrylate/Na acryloyldimethyltaurate) copolymer
0.2
Purified water 20.0
Part D Neosolue-AquaS (Nippon Fine Chemicals) 0.5
Polyquaternium-51 1.0
Ascorbyl Glucoside 1.0
Potassium hydroxide 0.2
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount to total 100 Part E 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.1
Carboxylated cellulose nanofiber (2% aqueous solution) 25.0
Carbomer 0.15
K hydroxide 0.06
Tremoist-TP (Nippon Fine Chemicals) 0.1
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling, add part C and part E at about 50°C, stir and cool to about 40°C.

Example 18 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Diisostearyl malate 5.0
Plandool-DP (Nippon Fine Chemicals) 1.0
Cetyl ethylhexanoate (Nippon Fine Chemicals) 10.0
Cetanol 1.2
Phenyltrimethicone 3.0
Ethylparaben 0.1
Myristyl alcohol 2.0
Oleyl alcohol 1.0
Part B Auro Visco CS (Oji Holdings) 10.0
Stealoxy hydroxypropyl methylcellulose 0.1
Xanthan gum 0.1
Purified water 20.0
Part C Phytocompo-PP (Nippon Fine Chemicals) 1.0
Pentylene glycol 3.0
Glycerin 8.0
Part D 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Purified water 5.0
Part E Phenoxyethanol 0.2
Methylparaben 0.15
Phytic acid 0.5
Citric acid Appropriate amount Na citrate Appropriate amount Purified water Amount that makes the total 100－－－－－－－－－－－－－－－－－－－－－ ----
(Preparation method)
Part A and part E were each heated to about 70° C. and dissolved uniformly. Part B was stirred to form a viscous liquid. Part C was heated to about 70° C. and evenly dispersed. After adding part A while stirring part C with a homodisper, part E was added while stirring. Part D and part B were added at about 50° C. and dissolved uniformly by stirring.

Example 19 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 3.0
Diglycerin 1.0
BG 7.0
Phytocompo-C (Nippon Fine Chemicals) 1.0
Hydrogenated Lysolecithin (Nippon Fine Chemicals) 0.1
Part B Mineral oil 5.0
Triethylhexanoin (Nippon Fine Chemicals) 3.0
LUSPLAN SR-DM4 (Nippon Fine Chemical) 0.5
Hydrogenated polyisobutene 3.5
Isododecane 1.5
Cetostearyl alcohol 1.0
Arachyl alcohol 0.1
Jojoba Alcohol 3.0
chimyl alcohol 0.3
Serachyl alcohol 0.1
Hexyldecanol 0.5
Part C (Hydroxyethyl acrylate/Na acryloyldimethyltaurate) copolymer
0.2
Purified water 20.0
Part D Neosolue-AquaS (Nippon Fine Chemicals) 0.5
Polyquaternium-51 1.0
Tranexamic acid 1.0
Potassium hydroxide 0.2
Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount to total 100 Part E 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.8
Auro Visco CS (Oji Holdings) 1.0
Tremoist-TP (Nippon Fine Chemicals) 0.1
Ethanol 10.0
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling, add part C and part E at about 50°C, stir and cool to about 40°C.

Example 20 Emulsion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-SP (Nippon Fine Chemicals) 8.0
Hydrogenated Lysophospholipid (Nippon Fine Chemicals) 0.1
Part B LUSPLAN SR-DM4 (Nippon Fine Chemicals) 5.0
Squalane 4.0
Caprylic/capric triglyceride (Nippon Fine Chemicals) 4.0
α-olefin oligomer 2.5
Cyclopentasiloxane 3.5
Cetanol 1.5
Glyceryl stearate 1.0
Part C DPG 5.0
Hydroxyproline 0.05
Citric acid 0.01
Na citrate 0.09
Phenoxyethanol 0.3
Methylparaben 0.1
Acrylic acid-alkyl methacrylate copolymer 0.1
K hydroxide 0.1
Purified water 100 in total Part D 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 15.0
Tremoist-TP (Nippon Fine Chemicals) 0.01
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Parts A to C were each taken, heated to about 70° C., and mixed homogeneously. After gradually adding part B to part A while stirring with a homodisper, part C was added at about 70° C. and emulsified. After cooling to about 40° C., the mixed Part D was added and mixed evenly.

Example 21 Cream
Ingredient Amount (% by mass)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-LG1 (Nippon Fine Chemicals) 0.5
Plandool-MAS (Nippon Fine Chemicals) 0.5
Plandool-H (Nippon Fine Chemicals) 0.5
Plandool-G (Nippon Fine Chemicals) 0.5
LUSPLAN PI-DA (Nippon Fine Chemicals) 0.5
Diethylhexyl succinate (Nippon Fine Chemicals) 3.0
behenyl alcohol 2.0
Stearyl alcohol 1.2
Glyceryl stearate 1.5
Polyglyceryl-10 isostearate 1.5
Ethylparaben 0.1
Part B Auro Visco CS (Oji Holdings) 10.0
Carboxylated cellulose nanofiber (2% aqueous solution) 10.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Arbutin (Nippon Fine Chemicals) 1.0
Nicotinamide 1.0
Purified water 10.0
Part D 1,3-butylene glycol 5.0
Glycerin 3.0
Neosolue-Aqulio (Nippon Fine Chemicals) 0.5
Etidronic acid 0.05
Sodium pyrosulfite 0.05
Citric acid 0.05
Na citrate Amount that makes pH 5.0 Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was mixed and heated to about 70° C. to dissolve uniformly. Part C was mixed and evenly dissolved. Part D was mixed and heated to about 70° C. to dissolve uniformly. After adding part D to part A and emulsifying with a homomixer, the mixture was cooled and added to part B and part C at about 50° C. and stirred to form a uniform liquid.

Example 22 Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Mineral oil 7.8
Vaseline 7.0
Squalane 0.2
Jojoba oil 0.15
Microcrystalline wax 2.4
Paraffin wax 2.0
Al Distearate 0.9
Hydrogenated polyisobutene 2.8
Lanolin alcohol (Nippon Fine Chemicals) 2.3
Octyldodecanol 3.0
Part B Mg sulfate 0.5
Sodium benzoate 0.1
Concentrated glycerin 3.5
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 13.0
Purified water 100 in total Part C Mg stearate 0.9
Cyclomethicone 2.5
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were dissolved by heating and dispersed uniformly. Part B was gradually added to part A, emulsified, mixed with dispersed part C, and cooled while stirring. Add part C at about 40° C. and mix evenly.

Example 23 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 9.0
DPG 5.0
Phytocompo-PP (Nippon Fine Chemicals) 1.0
Part B Mineral oil 8.0
Vaseline 10.0
Pentaerythrityl tetraisostearate 5.0
Astaxanthin 0.01
Cetyl PG hydroxyethyl palmitamide 0.05
Sodium cyclic lysophosphatidate 0.01
Dipentaerythrityl hexahydroxystearate 1.0
Part C Carbomer 0.1
K hydroxide 0.07
Xanthan gum 0.1
Purified water 10.0
Part D Phenoxyethanol 0.4
Ethylhexylglycerin 0.2
Methylparaben 0.05
Purified water Amount to be 100 in total Part E 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.7
Auro Visco CS (Oji Holdings) 4.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling, add part C and part E at about 50°C, stir and cool to about 40°C.

Example 24 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Squalane 10.0
Stearic acid 1.0
Plandool-ISS (Nippon Fine Chemicals) 1.0
Macadamia nut oil 3.0
Hydrogenated rapeseed oil alcohol 2.0
Olive oil fatty acid cetearyl 1.0
Olive oil fatty acid sorbitan 0.8
Polyglyceryl-10 oleate 1.0
Part B Auro Visco CS (Oji Holdings) 18.0
Acrylic acid-alkyl methacrylate copolymer 0.1
K hydroxide 0.07
(acryloyldimethyltaurate ammonium/
Beheneth methacrylate-25) Crosspolymer 0.2
Purified water 10.0
Hydrolyzed poly γ-glutamic acid K 0.1
Sodium polyglutamate 0.1
Oligopeptide-24 0.05
Part C Glycerin 9.0
Propanediol 10.0
PEG-8 5.0
Methylparaben 0.1
Phenoxyethanol 0.3
Purified water Amount to be 100 in total Part D 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 1.0
Tremoist-TP (Nippon Fine Chemicals) 0.05
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to a viscous liquid. Part D was mixed to form a uniform liquid. While stirring part C with a homomixer, part A was added and emulsified. After cooling to about 50°C, parts B and D were added, stirred and cooled to about 40°C.

Example 25 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Mineral oil 8.0
Plandool-MAS (Nippon Fine Chemicals) 2.0
Plandool-LG1 (Nippon Fine Chemicals) 1.0
Paraffin wax 3.0
Shea Butter 3.0
Squalane 8.0
Cetanol 1.8
Hydrogenated Cocoglyceryl 0.8
Glyceryl stearate 1.0
behenyl alcohol 1.5
Sorbitan Stearate 1.0
Methyl glucose sesquistearate 1.5
Part B Auro Visco CS (Oji Holdings) 30.0
Xanthan gum 0.1
Hydroxyethyl cellulose 0.1
Microcrystalline cellulose powder 0.3
Stealoxy hydroxypropyl methylcellulose 0.1
Purified water 20.0
Part C Glycerin 8.0
DPG 5.0
Sorbitol 2.0
Methylparaben 0.15
Purified water Amount to be 100 in total Part D 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 1.0
Tremoist-TP (Nippon Fine Chemicals) 0.1
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part B was mixed and stirred to a viscous liquid. Part D was mixed to form a uniform liquid. While stirring part C with a homomixer, part A was added and emulsified. After cooling to about 50°C, parts B and D were added, stirred and cooled to about 40°C.

Example 26 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 9.0
Phytocompo-C (Nippon Fine Chemicals) 1.0
Glucosylrutin 0.001
Part B Argania spinosa kernel oil 1.0
Theobroma Grange Florum Seed Oil 1.0
Astaxanthin 0.005
Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 0.5
Ethylhexyl Stearate 3.0
Plandool-ISS (Nippon Fine Chemical) 2.0
Carnauba wax 0.5
Steareth-2 2.5
Steareth-21 1.8
Cetanol 3.0
Tocopheryl Acetate 0.03
Squalane 6.0
Part C Carbomer 0.1
Auro Visco CS (Oji Holdings) 4.0
Arginine 0.1
Hydroxypropyl Chitosan 0.2
Ethanol 3.0
Purified water 10.0
Panthenol 0.5
Retinol palmitate 0.05
Part D Methylparaben 0.15
Purified water Amount to be 100 in total Part E 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.5
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling to about 50°C, add part C and part E, stir and cool to about 40°C.

Example 27 Skin care cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 12.0
BG 6.0
Phytocompo-PP (Nippon Fine Chemicals) 2.5
Part B Mineral Oil 3.0
Olive fruit oil 3.0
olive oil 1.5
Shea butter 1.0
Plandool-S (Nippon Fine Chemicals) 1.0
Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 3.0
Sucrose stearate 0.8
Cetearyl glucoside 1.2
behenyl alcohol 1.5
Ascorbyl Tetrahexyldecanoate 7.0
Lauroyl Sarcosine Isopropyl 2.0
Hydrogenated Cocoglyceryl 3.0
Cetanol 2.5
Sorbitan stearate 0.8
Part C xanthan gum 0.05
Tuberose polysaccharide 0.01
Water-soluble collagen 0.05
Hydrolyzed Collagen 0.5
Sodium pyrosulfite 0.03
Part D Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Propanediol 3.0
Methylparaben 0.1
Purified water Amount to be 100 in total Part E 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.4
Auro Visco CS (Oji Holdings) 10.0
Tremoist-TP (Nippon Fine Chemicals) 0.02
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. Part E was mixed to form a uniform liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling to about 50°C, add part C and part E, stir and cool to about 40°C.

Example 28 Hand Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Diisostearyl malate 8.0
Lanolin Fatty Acid Cholesteryl (Nippon Fine Chemicals) 5.0
LUSPLAN SR-DM4 (Nippon Fine Chemical) 0.1
Squalane 8.0
Macadamia nut oil 0.5
Rosehip oil 1.0
meadowfoam oil 1.0
Vaseline 15.0
Microcrystalline wax 2.0
Glyceryl stearate 2.0
Cetanol 2.0
Cetyl Phosphate 1.0
Beeswax 3.0
Propylparaben 0.1
Tocopherol 0.05
Perfluoropolyether 1.0
Part B Glycerin 8.0
1,2-Hexanediol 3.0
Methylparaben 0.1
Ethylhexylglycerin 0.5
Phenoxyethanol 0.3
Citric acid 0.10
Na citrate Amount that makes the pH 4.5 Water Amount that makes the total 100 Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.8
Auro Visco CS (Oji Holdings) 15.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part B was heated to about 70° C. and dissolved. Part A was placed in another container and heated to about 80° C. to dissolve. Part A was added to part B while stirring with a homomixer to emulsify. After emulsification and cooling to about 40° C., part C was added and mixed uniformly.

Example 29 Hand Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Vaseline 5.0
Plandool-G (Nippon Fine Chemicals) 0.5
(Dimethicone/vinyl dimethicone) crosspolymer 0.3
(vinyl dimethicone/lauryl dimethicone) crosspolymer 0.5
(Dimethicone/PEG-10/15) crosspolymer 0.5
(PEG-15/lauryl dimethicone) crosspolymer 0.2
(alkyl acrylate/dimethicone) copolymer 0.1
Cetyl ethylhexanoate (Nippon Fine Chemicals) 10.0
Propylparaben 0.1
Squalane 5.0
Part B Diglycerin 5.0
Methylparaben 0.1
Part C xanthan gum (2% aqueous solution) 2.0
Auro Visco CS (Oji Holdings) 10.0
(acrylamide/ammonium acrylate) copolymer 0.5
Water 100 in total Part D 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 1.0
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
After dissolving part B, add part A and warm to about 70° C. (part E). Part C was brought to about 70°C. Part C was added to part E while stirring, and the mixture was stirred and mixed with a homomixer for about 3 minutes. After cooling to about 40° C., the mixed Part D was added and mixed evenly.

Example 30 Hand Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Squalane 10.0
Vaseline 20.0
Polyglyceryl-10 Pentastearate 2.0
Microcrystalline wax 4.0
Sodium stearoyl lactylate 1.3
Al stearate 1.5
Mg stearate 1.0
Ca stearate 0.1
Part B LUSPLAN PI-DA (Nippon Fine Chemicals) 5.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
Plandool-DP (Nippon Fine Chemicals) 0.8
Cetyl ethylhexanoate (Nippon Fine Chemicals) 5.0
Triethylhexanoin (Nippon Fine Chemicals) 6.0
Propylparaben 0.05
Tocopherol 0.05
Cyclopentasiloxane 5.0
Part C Methylparaben 0.1
Auro Visco CS (Oji Holdings) 10.0
Glycerin 10.0
Water Total amount to be 100 Part D 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.6
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Each of B part and C part was heated to about 80° C. and dissolved. Part A was placed in another container, heated to 100 to 120°C, and cooled to 80°C to form a transparent gel. Part B was added to part A with stirring, and then part C was added and emulsified. After cooling to about 40° C., the mixed Part D was added and mixed evenly.

Example 31
eye cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Squalane 5.0
Diethylhexyl succinate (Nippon Fine Chemicals) 1.0
LUSPLAN PI-DA (Nippon Fine Chemicals) 0.5
Vaseline 2.0
Plandool-MAS (Nippon Fine Chemicals) 3.0
behenyl alcohol 2.0
Cetearyl alcohol 5.0
Beeswax 0.7
Polyglyceryl-10 stearate 0.7
Polyglyceryl-10 oleate 0.3
Glyceryl stearate (SE) 1.0
Tocopherol 0.1
Glycerin 3.0
BG 5.0
Part B Citric acid 0.1
Na citrate pH adjusted to 4.5 Phenoxyethanol 0.4
EDTA-2Na 0.05
Purified water 100 in total Part C Auro Visco CS (Oji Holdings) 20.0
Xanthan gum 0.2
Dimethicone 0.5
3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. Part B was added while part A was stirred with a homodisper. Cool, add part C and mix evenly.

Example 32 Cleansing gel
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Cetyl ethylhexanoate (Nippon Fine Chemicals) 10.0
Plandool-S (Nippon Fine Chemicals) 1.0
Dihydrocholeth-3 (Nippon Fine Chemicals) 2.0
LUSPLAN DD-IS (Nippon Fine Chemical) 8.0
PEG-25 hydrogenated castor oil 20.0
Octyldodeceth-20 15.0
Glycerin 16.0
BG 5.0
Part B Phenoxyethanol 0.5
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 4.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were each heated to about 80° C. and dissolved. Mixed and warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C. Part C was added and mixed evenly.

Example 33 Cleansing Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Neosolue-DE (Nippon Fine Chemicals) 5.0
Glycerin 3.0
Plandool-LG2 (Nippon Fine Chemicals) 1.0
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Seresin 6.0
Mineral oil 28.0
PEG-12 Isostearate 3.0
Sorbitan Sesquioleate 1.5
Polyoxyethylene sorbitan oleate 0.3
Microcrystalline wax 2.0
Tocopherol 0.05
Propylparaben 0.05
Part B DPG 5.0
Auro Visco CS (Oji Holdings) 40.0
Methylparaben 0.2
Edetate 3Na 0.02
Phenoxyethanol 0.2
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 0.4
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were each heated to about 80° C. and dissolved. Mixed and warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C. Part C was added and mixed evenly.

Example 34 Cleansing foam
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A K stearate 10.0
Potassium palmitate 10.0
Potassium myristate 10.0
Potassium Laurate 4.0
Lauroyl sarcosine isopropyl 0.8
PEG1500 10.0
Glycerin 15.0
Glyceryl monostearate 1.0
POE(20) sorbitan monostearate 2.0
Part B Polyquaternium-7 0.5
Polyquaternium-39 0.5
Methylparaben 0.1
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 1.0
Auro Visco CS (Oji Holdings) 20.0
Carboxylated cellulose nanofiber (2% aqueous solution) 3.0
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was dissolved by heating to about 80°C. Part B was warmed to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C. Part C was added and mixed evenly.

Example 35 Cleansing foam
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A (coconut fatty acid/hydrogenated beef tallow fatty acid) sodium glutamate 30.0
Cocoylglycine K 5.0
coconut oil alkyl glucoside 1.0
Plandool-LG2 (Nippon Fine Chemicals) 0.2
Lauric acid diethanolamide 3.0
Tocopherol 0.1
PEG-8 5.0
Glycerin 14.0
Propylparaben 0.1
Part B Methylparaben 0.2
Polyquaternium-51 1.0
Microcrystalline cellulose 0.3
Polyquaternium-7 0.8
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.9
Auro Visco CS (Oji Holdings) 10.0
Tremoist-TP (Nippon Fine Chemicals) 0.02
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was dissolved by heating to about 80°C. Warm part B to about 80°C. Part B was gradually added to part A while stirring, and after mixing, the mixture was cooled to 40°C. Part C was added and mixed evenly.

Example 36 Cleansing powder
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Cornstarch Total 100 K myristate 10.0
Sorbitol 5.0
Inulin-SC 3.0
Cocoylglycine Na 3.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.05
Auro Visco CS (Oji Holdings) 1.0
BG 0.5
Silica 1.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was evenly mixed.

Example 37 Non-Silicone Shampoo
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Plandool-LG2 (Nippon Fine Chemicals) 0.03
Diethylhexyl succinate (Nippon Fine Chemicals) 0.01
Neosolue-AquaS (Nippon Fine Chemicals) 0.1
Tremoist-SL (Nippon Fine Chemical) 0.5
Sodium laureth-4 carboxylate (28%) 10.0
Laureth-6 carboxylic acid 4.0
Cocamidopropyl betaine (30%) 10.0
Lauroylmethylalanine Na (30%) 5.0
Cocamidomethyl MEA 3.0
Coconut Fatty Acid PEG-7 Glyceryl 5.0
Na hydroxide 1% liquid 0.5
Polyquaternium-10 0.8
Glycol distearate 0.5
Polyquaternium-7 0.5
EDTA-2Na 0.05
1,2-Pentanediol 5.0
Phenoxyethanol 0.4
Sodium benzoate 0.2
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.2
Auro Visco CS (Oji Holdings) 15.0
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
All the ingredients were heated to about 80° C. and uniformly stirred and mixed.

Example 38 Leave-in hair treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Polyquaternium-37 2.0
Squalane 2.0
PPG-3 caprylyl ether 2.0
Microcrystalline wax 0.1
Lanolin alcohol 0.2
sunflower seed wax 0.1
Polyethylene wax 0.1
Mokurou 0.2
Seresin 0.1
PG Dicaprate 1.0
almond oil 0.5
Ethylhexyl Ethylhexanoate 1.0
Candelilla wax extract 0.1
Octyldodecyl erucate 4.5
Plandool-DP (Nippon Fine Chemicals) 0.2
Tocopherol Acetate 0.02
Erucalactone MCT (Nippon Fine Chemicals) 2.0
Dipentaerythrityl Tripolyhydroxystearate 1.5
PPG-5 Phytosteryl 0.5
1,2-Pentanediol 5.0
Glycerin 4.0
Sorbitol 2.0
Phenoxyethanol 0.5
Part B Hydrolyzed hyaluronic acid 0.1
Panthenol 0.1
Hydroxypropyltrimonium Hyaluronate 0.01
Polyquaternium-11 0.2
Glycosyltrehalose 0.1
Glyceryl glucoside 0.3
Arginine 0.1
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.1
Auro Visco CS (Oji Holdings) 4.0
Part C Purified water Amount for a total of 100 Hydroxypropyl starch phosphate 1.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part C was evenly dispersed and warmed to about 80°C. Next, part A was heated to about 80° C. and dissolved. Part A was added to part C while stirring, and after uniform mixing, the mixture was cooled to about 40°C. Part B was then added respectively and mixed uniformly.

Example 39 Non-Silicone Hair Treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-LG2 (Nippon Fine Chemicals) 0.5
Propanediol 3.0
behenamidopropyl dimethylamine 1.5
Cetanol 2.2
Stearyl alcohol 0.8
Hydrogenated rapeseed oil alcohol 0.5
Neopentyl glycol diethylhexanoate 0.8
Jojoba seed oil 1.0
Isododecane 1.0
Glyceryl stearate 0.4
Propylparaben 0.1
Cocamidomethyl MEA 0.8
Caesalpinia spinosa hydroxypropyltrimonium chloride 0.1
Rice bran wax 0.5
Erucalactone DES (Nippon Fine Chemicals) 2.0
Glycerin 1.0
Part B 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Phosphatidylinositol 0.05
Hydrogenated lecithin 0.1
1,2-Pentanediol 3.0
Purified water 20.0
Part C Phenoxyethanol 0.4
Tremoist-SL (Nippon Fine Chemical) 1.0
Lactic acid 0.4
Auro Visco CS (Oji Holdings) 15.0
Purified water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were each uniformly mixed at about 80°C. Part B was evenly dispersed at about 70°C. Part C was gradually added to part A with stirring, mixed uniformly, and then cooled to about 50°C. Part B was added and mixed uniformly.

Example 40 Shampoo for Dandruff
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A PPG-3 caprylyl ether 0.2
Lauroyl methylalanine Na (30%) 13.0
Cocamidopropyl betaine (30%) 20.0
Cocoyl glutamic acid TEA (30%) 5.0
Cocamide DEA 1.0
1,2-Pentanediol 3.0
Glycerin 1.0
Glyceryl Caprylate 0.4
Glyceryl undecylenate 0.1
Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Sorbitol 1.6
Miconazole nitrate 0.75
Glycol Distearate 1.5
Polyquaternium-7 0.3
Part B Sodium Benzoate 0.4
Na chloride 0.2
Purified water Amount to be 100 in total Part C 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 25.0
Assembly Extract 3.0
Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Polyquaternium-47 0.1
Piroctone Olamine 0.1
Purified water 9.7
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part B was heated to about 80° C. and dissolved uniformly. Part A was placed in a separate container and heated to dissolve. Gradually add part B to part A, mix evenly and add part C at about 60°C.

Example 41 Shampoo
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Neosolue-DiSM (Nippon Fine Chemicals) 0.3
Cocoyl sarcosine Na 10.0
Sodium cocoyl glutamate (30%) 10.0
Lauryl hydroxysultaine (30%) 10.0
Glycol distearate 0.5
Stealoxypropyldimethylamine 0.5
Neosolue-AquaS (Nippon Fine Chemicals) 0.5
Isostearic acid 0.3
Glyceryl undecylenate 0.5
BG 0.1
Cocamidomethyl MEA 3.0
Phenoxyethanol 0.6
Part B Citric acid 0.1
Methylparaben 0.2
EDTA-2Na 0.1
Purified water 100 in total Part C Polyquaternium-10 0.2
Guar hydroxypropyltrimonium chloride 0.1
Tremoist-SL (Nippon Fine Chemical) 3.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Auro Visco CS (Oji Holdings) 5.0
Purified water 6.7
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was uniformly mixed at about 80°C. Part B, which was set aside separately, was heated to about 60° C. and homogenized. Part B was gradually added to part A with stirring, mixed uniformly, and then cooled to about 50°C. Further, part C was added and mixed uniformly.

Example 42 Leave-on Hair Treatment
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Neosolue-Aqulio (Nippon Fine Chemicals) 2.0
Cetrimonium chloride (25%) 3.8
Isostearic acid 0.02
Erucalactone DES (Nippon Fine Chemicals) 1.0
Caprylyl glucoside (50%) 0.8
Glycerin 4.0
1,2-hexanediol 2.0
Phenoxyethanol 0.5
Part B Ethanol 10.0
Part C Hydrolyzed Keratin 0.2
Hydrolyzed silk 0.1
Hydrolyzed Conchiolin 0.1
Polyquaternium-6 0.6
Polyquaternium-7 0.4
Polyquaternium-39 0.5
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 30.0
Purified water Amount that makes a total of 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part C was warmed to about 80° C. and dissolved. Next, part A was heated to about 80° C. and dissolved. Part A was added to part C while stirring, and after mixing uniformly, the mixture was cooled to about 40°C. Part B was then added and mixed evenly.

Example 43 Water-Containing Gloss
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Octyldodecanol 27.0
Ethyl cellulose 2.5
Hydrogenated polyisobutene 10.0
Isopropyl Sebacate (Nippon Fine Chemicals) 3.0
LUSPLAN PI-DA (Nippon Fine Chemicals) 2.0
Plandool-G (Nippon Fine Chemicals) 0.1
Plandool-SUN (Nippon Fine Chemicals) 0.1
Plandool-ISS (Nippon Fine Chemicals) 0.1
Plandool-LG1 (Nippon Fine Chemicals) 0.1
Plandool-LG2 (Nippon Fine Chemicals) 0.1
Plandool-LG3 (Nippon Fine Chemicals) 0.1
Plandool-LG4 (Nippon Fine Chemicals) 0.1
Silica dimethyl silylate 0.5
Dextrin Palmitate 0.1
PEG-60 hydrogenated castor oil 1.0
Red No. 202 Appropriate amount Red No. 218 Appropriate amount Red No. 223 Appropriate amount Orange No. 201 Appropriate amount Sorbitan stearate, sucrose coconut fatty acid mixture (ALACEL2121 manufactured by Croda Co., Ltd.) 3.0
Part B 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.8
Auro Visco CS (Oji Holdings) 4.0
Glycerin 7.0
Neosolue-AquaS (Nippon Fine Chemicals) 0.4
Maltose 2.0
Phenoxyethanol 0.2
Water Total 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were melted by heating and homogenized, and part B was mixed with part A.

Example 44 Liquid Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Plandool-G (Nippon Fine Chemicals) 5.0
Glyceryl stearate (SE) 1.0
PG stearate (SE) 1.0
Tocopherol 0.1
Propylparaben 1.0
Part B Titanium oxide/iron oxide mixture (FDP-W-007 manufactured by Toshiki Pigment Co., Ltd.) 18.0
Mica 7.0
BG 5.0
Methylparaben 0.2
Purified water 100 in total Part C Cellulose gum (2% aqueous dispersion) 5.0
Xanthan gum (2% aqueous dispersion) 5.0
Auro Visco CS (Oji Holdings) 4.0
Part D 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.8
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B and part C were heated and mixed. After adding part B to part A and emulsifying the mixture, the mixture was cooled to about 50°C, and then parts C and D were added and stirred until uniform.

Example 45 Liquid Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Purified water Total 100 3-O-ethyl ascorbic acid (Nippon Fine Chemicals) 1.0
Auro Visco CS (Oji Holdings) 10.0
Carboxyvinyl polymer 0.1
Potassium hydroxide Appropriate amount DPG 5.0
Preservative Appropriate amount Part B Polyoxyethylene-modified dimethylpolysiloxane 1.0
Trimethylsiloxysilicate 3.0
Phenylmethicone 1.0
Cyclomethicone 9.0
Part C Zinc white 10.0
Sericite 0.36
Titanium oxide 8.32
Iron oxide yellow 0.8
Iron oxide red 0.36
Iron oxide black 0.16
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
After heating and stirring Part A to 70° C., Part C was added and dispersed. This was preliminarily heated to 70° C. and added to part B to emulsify and disperse. Cool to about 40° C. and mix uniformly.

Example 46 Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Hydrogenated polyisobutene 5.0
Cyclopentasiloxane 4.0
mineral oil 4.0
Ethylhexyl methoxycinnamate 3.0
Plandool-H (Nippon Fine Chemicals) 1.0
Plandool-G (Nippon Fine Chemicals) 1.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
Vaseline 1.0
Phenyltrimethicone 2.0
Sorbitan Isostearate 1.5
Tribehenin 0.5
(butyl acrylate/glycol dimethacrylate) crosspolymer,
Silica, (methyl methacrylate/glycol dimethacrylate)
Crosspolymer mixture 2.0
Boron Nitride 1.0
PEG/PPG-19/19 dimethicone,
Cyclopentasiloxane mixture 4.0
Disteardimonium hectorite (20%) 2.5
Polypropylsilsesquioxane, cyclopentasiloxane mixture
1.0
Mica 15.0
Talc 4.0
Zinc oxide 5.0
Titanium oxide 10.0
Iron oxide 1.5
Part B Water Total 100 DPG 4.0
Maltitol (75% liquid) 1.0
Neosolue-AquaS (Nippon Fine Chemicals) 0.4
Na chloride 1.0
BG 1.0
Hyaluronic acid (1% liquid) 0.1
Phenoxyethanol 0.3
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.6
Auro Visco CS (Oji Holdings) 4.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was heated to about 70° C. and thoroughly stirred to uniformly disperse. Part B was heated to about 70°C and homogenized, then part B was added to part A, emulsified with stirring at about 70°C, and cooled to about 40°C.

Example 47 Base cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A LUSPLAN DD-DA7 (Nippon Fine Chemicals) 5.0
Cyclomethicone 14.0
Trimethylsiloxysilicate 3.0
Glyceryl stearate (SE) 2.0
PG stearate (SE) 2.0
Plandool-MAS (Nippon Fine Chemicals) 0.5
Stearic acid 0.5
Palmitic acid 0.5
Ethylhexyl methoxycinnamate 0.5
Tocopherol 0.2
Part B BG 10.0
Ethanol 1.0
Mica 8.0
Talc 7.0
Phenoxyethanol 0.8
Titanic acid (Li/cobalt) 0.2
Purified water Amount to total 100 Part C Dextrin (1%) 1.0
Xanthan gum (10%) 1.0
Cellulose gum (10%) 1.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Auro Visco CS (Oji Holdings) 10.0
Purified water 15.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part B were heated and dissolved in separate containers. Part B was added to part A and emulsified, then part C was added and mixed uniformly. After stirring, the mixture was cooled to 40°C.

Example 48 Sunscreen cosmetics
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Quaternium-18 Hectorite 1.0
Part B Cyclomethicone 13.7
Diphenyl dimethicone 2.0
Cyclopentasiloxane 10.0
Plandool-H (Nippon Fine Chemicals) 1.0
Plandool-G (Nippon Fine Chemicals) 0.5
Plandool-MAS (Nippon Fine Chemicals) 2.0
Dicaprylyl carbonate 1.0
Dimethicone copolyol 5.5
Part C Silicone treated fine titanium dioxide 3.9
Siliconized zinc oxide 2.1
Part D Al stearate 0.7
Al hydroxide 0.5
isononyl isononanoate 2.5
Neosolue-MP (Nippon Fine Chemicals) 1.0
Neosolue-DE (Nippon Fine Chemicals) 1.0
Part E Trimethylsiloxysilicate 1.2
Stearyl Glycyrrhetinate 0.02
Sorbitan Sesquioleate 2.0
Tocopherol 0.02
Part F Na chloride 1.0
Methylparaben 0.15
Purified water Amount to be 100 in total G part 3-O-ethyl ascorbic acid (Nippon Fine Chemical) 1.0
Auro Visco CS (Oji Holdings) 10.0
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A is added to part B and stirred. Further C was added and dispersed using a roller mill. Part D was melted by heating and added to the mixture of parts A, B and C, then part E was added and brought to about 70°C. Part F was warmed and gradually emulsified into the mixture of parts A to E with stirring. Cool while stirring and add part G at 40-35° C. and mix uniformly.

Example 49 Sunscreen cosmetics
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-PP (Nippon Fine Chemicals) 1.0
BG 10.0
Glycerin 9.0
Part B Octocrylene 4.0
Octyl Salicylate 4.0
Diethylaminohydroxybenzoyl hexyl benzoate 2.25
t-Butyl methoxydibenzoylmethane 1.0
Diethylhexyl Sebacate (Nippon Fine Chemicals) 3.0
Pentaerythrityl tetraethylhexanoate (Nippon Fine Chemicals) 2.0
Isopropyl Sebacate (Nippon Fine Chemicals) 1.0
behenyl alcohol 2.0
Cetearyl alcohol 2.0
Plandool-MAS (Nippon Fine Chemicals) 1.0
Tocopherol 0.05
Part C Neosolue-AquaS (Nippon Fine Chemicals) 1.0
Methylparaben Appropriate amount Water Total amount to be 100 Part D Carbomer (2%) 5.0
Water-dispersed titanium oxide 5.0
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.5
Auro Visco CS (Oji Holdings) 24.0
Tremoist-TP (Nippon Fine Chemicals) 0.1
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was evenly dispersed. Part B and part C were heated to about 70° C. and dissolved. After gradually adding part B to part A, part C was gradually added and emulsified. The mixture was cooled while stirring, and part D was added at 45°C and stirred.

Example 50 Sunscreen cosmetics
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-PP (Nippon Fine Chemicals) 1.0
BG 10.0
Glycerin 9.0
Part B Ethylhexyl methoxycinnamate 7.0
Diethylaminohydroxybenzoyl hexyl benzoate 7.0
Behenyl alcohol 4.0
Plandool-LG1 (Nippon Fine Chemicals) 0.5
Plandool-MAS (Nippon Fine Chemicals) 1.0
Part C Methylparaben 0.15
Purified water 100 in total Part D Xanthan gum 0.2
Sodium hyaluronate 0.01
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.7
Auro Visco CS (Oji Holdings) 4.0
Carboxylated cellulose nanofiber (2% aqueous solution) 2.0
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was evenly dispersed. Part B and part C were heated to about 70° C. and dissolved. After gradually adding part B to part A, part C was gradually added and emulsified. After cooling while stirring, the D part and the E part were added at 45° C. and mixed uniformly.

Example 51 Sunscreen cosmetics
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytocompo-PP (Nippon Fine Chemicals) 1.0
BG 10.0
Glycerin 9.0
Part B Ethylhexyl methoxycinnamate 7.0
Diethylaminohydroxybenzoyl hexyl benzoate 7.0
Behenyl alcohol 4.0
Plandool-LG2 (Nippon Fine Chemicals) 0.5
Plandool-MAS (Nippon Fine Chemicals) 1.0
Part C Methylparaben 0.15
Purified water 100 in total Part D Xanthan gum 0.2
Sodium hyaluronate 0.01
3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.7
Carboxylated cellulose nanofiber (2% aqueous solution) 10.0
Purified water 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was evenly dispersed. Part B and part C were heated to about 70° C. and dissolved. After gradually adding part B to part A, part C was gradually added and emulsified. After cooling while stirring, the D part and the E part were added at 45° C. and mixed uniformly.

Example 52 Skin Care Oil
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Olive oil 24.0
Squalane 24.0
Caprylic/capric triglyceride (Nippon Fine Chemicals) 10.0
Plandool-SUN (Nippon Fine Chemical) 2.0
Tocopherol 0.1
Part B 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.3
Auro Visco CS (Oji Holdings) 5.0
Neosolue-AquaS (Nippon Fine Chemicals) 0.5
NaCl 0.1
Methylparaben 0.1
Phenoxyethanol 0.4
Water Amount that sums to 100－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A was warmed to 50° C., dissolved homogeneously and cooled to room temperature. Part B was warmed to 80°C, dissolved homogeneously and cooled to about 40°C. Mix with Part A and Part B.

Example 53 Cream
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Glycerin 9.0
DPG 5.0
Phytocompo-PP (Nippon Fine Chemicals) 1.0
Part B Mineral oil 8.0
Vaseline 10.0
Pentaerythrityl tetraisostearate 5.0
Astaxanthin 0.01
Cetyl PG hydroxyethyl palmitamide 0.05
Sodium cyclic lysophosphatidate 0.01
Dipentaerythrityl hexahydroxystearate 1.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Xanthan gum 0.1
Purified water 10.0
Part D Phenoxyethanol 0.4
Ethylhexylglycerin 0.2
Methylparaben 0.05
Purified water Amount to total 100 Part E Carboxylated cellulose nanofiber (2% aqueous solution) 30.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A, part B, and part D were mixed, heated to about 70° C., and uniformly dissolved and dispersed. Part C was mixed and stirred to a viscous liquid. After adding part B while stirring part A with a homodisper, part D was added and emulsified. After cooling, add part C and part E at about 50°C, stir and cool to about 40°C.

Example 54 Lotion
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Phytopresome (Nippon Fine Chemicals) 0.2
BG 10.0
Part B Purified water 20.0
Part C 3-O-ethylascorbic acid (Nippon Fine Chemicals) 0.8
Neosolue-Aqulio (Nippon Fine Chemicals) 1.0
Succinic acid 0.1
Sodium succinate Appropriate amount Phenoxyethanol 0.2
Methylparaben 0.15
Purified water Amount that totals 100 Part D Carboxylated cellulose nanofiber (2% aqueous solution) 10.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Mix part A and slowly add to part B with stirring. Further, pre-mixed parts C and D were added to obtain a uniform liquid.

Example 55 Sunscreen
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Ethylhexyl methoxycinnamate 10.0
Dimethicone 25.0
Trimethylsiloxysilicate, Polypropylsilsesquioxane 4.0
PEG-10 Dimethicone 4.0
Isododecane, disteardimonium hectorite, propylene carbonate 4.0
Part B Titanium oxide, hydrous silica, hydrodimethicone 5.0
Part C Water Total 100 Auro Visco CS (Oji Holdings) 1.0
Ethanol 3.0
BG 6.0
Phenoxyethanol 0.4
Part D 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
Part A and part C were dissolved by heating to about 80°C. After adding part B to part A, part C was gradually added and emulsified. The mixture was cooled while stirring, and part D was added at 45°C and stirred.

Example 56 Foundation
Ingredient Amount (% by weight)
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
Part A Ethylhexyl methoxycinnamate 6.0
Titanium oxide, Al hydroxide, dimethicone 12.0
Iron oxide, dimethicone 1.4
Part B Dimethicone 23.0
Trimethylsiloxysilicate, Polypropylsilsesquioxane 3.0
PEG-10 Dimethicone 4.0
Part C: synthetic fluorophlogopite (synthetic phlogopite), hydrogen dimethicone 3.0
Silica dimethylsilylate 1.5
Isododecane, disteardimonium hectorite, propylene carbonate 3.0
Part D Purified water Amount that makes a total of 100 Auro Visco CS (Oji Holdings) 1.0
Ethanol 3.0
BG 6.0
Phenoxyethanol 0.4
Part E 3-O-ethylascorbic acid (Nippon Fine Chemicals) 1.0
Purified water 5.0
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－
(Preparation method)
After part A is kneaded, part B is added and heated to 80°C. After mixing part C, part D dissolved by heating to about 80° C. is added and emulsified. After cooling with stirring, part E was added at 45° C. and stirred.

In the above formulation, the details of the ingredients described in the product names are as follows.

〇 LUSPLAN PI-DA: di(isostearyl/phytosteryl) dimer dilinoleate
〇 LUSPLAN DD-IS: dimer dilinoleyl diisostearate 〇 LUSPLAN DD-DA7: dimer dilinoleyl dimer dilinoleate 〇 LUSPLAN SR-DM4: dimer dilinoleyl dimer dilinoleate, tri(caprylic/capric) glyceryl ○ Inulin-SC: inulin ○ Neosolue-Aqulio: bisethoxydiglycol cyclohexanedicarboxylate ○ Neosolue-Aqua: (eicosanedioic acid / tetradecanedioic acid) polyglyceryl-10
○Neosolue-AquaS: (Eicosanedioic acid/tetradecanedioic acid) polyglyceryl-10
〇Neosolue-DiSM: diisostearyl malate 〇Neosolue-DE: diethylpentanediol dineopentanoate 〇Neosolue-MP: methylpentanediol dineopentanoate 〇Plandool-DP: bisdiglyceryl polyacyladipate-2
〇 Plandool-ISS: Phytosteryl isostearate 〇 Plandool-SUN: Sunflower seed oil fatty acid phytosteryl 〇 Plandool-MAS: Macadamia nut oil fatty acid phytosteryl 〇 Plandool-LG1: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
○ Plandool-LG2: Lauroyl glutamate di(phytosteryl/octyldodecyl)
○ Plandool-LG3: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
○ Plandool-LG4: Lauroyl glutamate di(phytosteryl/octyldodecyl/behenyl)
〇 Plandool-G: dimer dilinoleyl bis(behenyl/isostearyl/phytosteryl) dimer dilinoleate
〇Plandool-H: dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl)
〇Plandool-S: dimer dilinoleic acid (phytosteryl/isostearyl/cetyl/stearyl/behenyl)
○ Phytopresome: hydrogenated lecithin, phytosterol ○ Phytopresome MEL: glycolipid, hydrogenated lecithin, BG, purified water ○ Phytocompo-PP: hydrogenated lecithin, phytosterol Ceramide 6II
○ PrimeLipid PI: Hydrogenated lecithin, lecithin, phytosterol, tocopherol ○ Tremoist-SL: White fungus polysaccharide solution (1%)
〇 Tremoist-TP: White jellyfish polysaccharide 〇 Erucalactone DES: γ-docosalactone, diethyl sebacate 〇 Erucalactone MCT: γ-docosalactone, tri (caprylic acid / capric acid) glyceryl

Claims (4)

A cosmetic or external preparation for skin containing the following components (A) and (B).
(A) Cellulose nanofibers with anionic functional groups (B) 3-O-ethylascorbic acid 2. The cosmetic or external preparation for skin according to claim 1, further comprising, as component (C), one or more selected from monohydric alcohols having 1 to 3 carbon atoms and polyhydric alcohols. 3. The cosmetic or external preparation for skin according to claim 1, further comprising a chelating agent as component (D). 4. The cosmetic or topical preparation for skin according to any one of claims 1 to 3, wherein the anionic functional group of component (A) is a phosphate group.