JP2023011857A5 - - Google Patents
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- Publication number
- JP2023011857A5 JP2023011857A5 JP2022177061A JP2022177061A JP2023011857A5 JP 2023011857 A5 JP2023011857 A5 JP 2023011857A5 JP 2022177061 A JP2022177061 A JP 2022177061A JP 2022177061 A JP2022177061 A JP 2022177061A JP 2023011857 A5 JP2023011857 A5 JP 2023011857A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- fusion protein
- chemotherapeutic agents
- antimicrobial agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662306281P | 2016-03-10 | 2016-03-10 | |
| US62/306,281 | 2016-03-10 | ||
| PCT/US2017/021715 WO2017156356A1 (en) | 2016-03-10 | 2017-03-10 | Methods of producing aggregate-free monomeric diphtheria toxin fusion proteins and therapeutic uses |
| JP2018547409A JP2019512233A (ja) | 2016-03-10 | 2017-03-10 | 凝集体を含まない単量体のジフテリア毒素融合タンパク質の生成方法及び治療的使用法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018547409A Division JP2019512233A (ja) | 2016-03-10 | 2017-03-10 | 凝集体を含まない単量体のジフテリア毒素融合タンパク質の生成方法及び治療的使用法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023011857A JP2023011857A (ja) | 2023-01-24 |
| JP2023011857A5 true JP2023011857A5 (https=) | 2023-06-15 |
| JP7532475B2 JP7532475B2 (ja) | 2024-08-13 |
Family
ID=59789900
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018547409A Pending JP2019512233A (ja) | 2016-03-10 | 2017-03-10 | 凝集体を含まない単量体のジフテリア毒素融合タンパク質の生成方法及び治療的使用法 |
| JP2022177061A Active JP7532475B2 (ja) | 2016-03-10 | 2022-11-04 | 凝集体を含まない単量体のジフテリア毒素融合タンパク質の生成方法及び治療的使用法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018547409A Pending JP2019512233A (ja) | 2016-03-10 | 2017-03-10 | 凝集体を含まない単量体のジフテリア毒素融合タンパク質の生成方法及び治療的使用法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10988512B2 (https=) |
| EP (1) | EP3426785A4 (https=) |
| JP (2) | JP2019512233A (https=) |
| KR (1) | KR102430891B1 (https=) |
| CN (2) | CN118599011A (https=) |
| AU (1) | AU2017230792B2 (https=) |
| BR (1) | BR112018068055A2 (https=) |
| CA (1) | CA3017143A1 (https=) |
| IL (2) | IL261660A (https=) |
| MX (1) | MX2018010850A (https=) |
| WO (2) | WO2017156356A1 (https=) |
| ZA (1) | ZA201806450B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3596108A4 (en) | 2017-03-15 | 2020-12-23 | Pandion Operations, Inc. | TARGETED IMMUNOTOLERANCE |
| US10676516B2 (en) | 2017-05-24 | 2020-06-09 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
| US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| EP3762401A4 (en) * | 2018-03-06 | 2021-12-08 | The Johns Hopkins University | CANCER TREATMENT OR PREVENTION METHODS USING TREG DEPLETING AGENT AND CHECKPOINT INHIBITOR |
| BR112021023345A2 (pt) | 2019-05-20 | 2022-02-01 | Pandion Operations Inc | Imunotolerância com alvo em madcam |
| MX2022000052A (es) * | 2019-07-01 | 2022-04-06 | Eisai R&D Man Co Ltd | Sistema para aumentar el cumplimiento terapéutico del compuesto antineoplásico e7766. |
| EP3845556A1 (fr) * | 2019-12-31 | 2021-07-07 | Peptinov SAS | Conjugue immunogene destine a induire une reponse immunitaire dirigee contre l interleukine-6 |
| EP4107187A4 (en) | 2020-02-21 | 2024-07-03 | Pandion Operations, Inc. | TISSUE-TARGETED IMMUNOTOLERANCE WITH A CD39 EFFECTOR |
| KR20230102682A (ko) * | 2021-12-30 | 2023-07-07 | (주)셀트리온 | 목적 단백질의 발현 방법 |
| CN114903896B (zh) * | 2022-05-30 | 2023-07-25 | 广西大学 | 贝达喹啉在制备治疗弓形虫病药物中的应用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549855B1 (fr) * | 1983-07-29 | 1987-03-27 | Grp Genie Genetique | Sequence nucleotidique codant pour le peptide signal de la toxine diphterique, vecteur contenant cette sequence nucleotidique, leur application a la transformation de micro-organismes et compositions peptidiques obtenues |
| US6022950A (en) | 1984-06-07 | 2000-02-08 | Seragen, Inc. | Hybrid molecules having translocation region and cell-binding region |
| US5668255A (en) | 1984-06-07 | 1997-09-16 | Seragen, Inc. | Hybrid molecules having translocation region and cell-binding region |
| CA1340494C (en) * | 1988-05-19 | 1999-04-13 | The Beth Israel Hospital Association And Brigham And Women's Hospital | Induction of tolerance to a foreign antigen |
| US5725871A (en) | 1989-08-18 | 1998-03-10 | Danbiosyst Uk Limited | Drug delivery compositions comprising lysophosphoglycerolipid |
| US5707644A (en) | 1989-11-04 | 1998-01-13 | Danbiosyst Uk Limited | Small particle compositions for intranasal drug delivery |
| WO1991013090A1 (en) | 1990-03-02 | 1991-09-05 | Diane Williams | Improved chimeric toxins |
| US5466468A (en) | 1990-04-03 | 1995-11-14 | Ciba-Geigy Corporation | Parenterally administrable liposome formulation comprising synthetic lipids |
| NO175188C (no) * | 1990-06-27 | 1994-09-14 | Sjur Olsnes | Fremgangsmåte for fremstilling av et peptidkonjugat med evne til å trenge inn i cellecytosol |
| US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| DK0590060T3 (da) | 1991-06-21 | 1998-05-11 | Univ Cincinnati | Oralt indgivelige terapeutiske proteiner samt fremgangsmåde til fremstilling |
| US5756353A (en) | 1991-12-17 | 1998-05-26 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol-and liposome-based delivery |
| ES2105262T3 (es) | 1992-05-18 | 1997-10-16 | Minnesota Mining & Mfg | Dispositivo de suministro de farmaco a traves de las mucosas. |
| US5792451A (en) | 1994-03-02 | 1998-08-11 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| ATE280235T1 (de) | 1993-03-05 | 2004-11-15 | Wyeth Corp | Plasmid zur herstellung von crm-protein und diphtherie-toxin |
| US5543158A (en) | 1993-07-23 | 1996-08-06 | Massachusetts Institute Of Technology | Biodegradable injectable nanoparticles |
| US5654273A (en) | 1994-09-22 | 1997-08-05 | Children's Medical Center Corporation | Synducin mediated modulation of tissue repair |
| US5580579A (en) | 1995-02-15 | 1996-12-03 | Nano Systems L.L.C. | Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers |
| IE80468B1 (en) | 1995-04-04 | 1998-07-29 | Elan Corp Plc | Controlled release biodegradable nanoparticles containing insulin |
| US6737514B1 (en) | 1998-12-22 | 2004-05-18 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
| US6613308B2 (en) | 2000-09-19 | 2003-09-02 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
| WO2004007663A2 (en) | 2002-05-22 | 2004-01-22 | Advanced Microbial Solutions Corporation | Gene expression using metal ion dependent repressor/operator tandems |
| EP1687016A4 (en) * | 2003-11-25 | 2009-07-29 | Anjin Corp | GENETIC VARIANT OF DIPHTHERIC TOXIN |
| AU2006260240B2 (en) * | 2005-06-21 | 2012-03-15 | The Research Foundation For Microbial Diseases Of Osaka University | Therapeutic agent for cancer |
| AU2008279550B2 (en) | 2007-06-21 | 2012-08-09 | Angelica Therapeutics, Inc. | Modified toxins |
| EP2600843B9 (en) * | 2010-07-19 | 2020-03-11 | Pressure BioSciences, Inc. | Therapeutic protein compositions having reduced immunogenicity and/or improved efficacy |
| WO2012039954A2 (en) * | 2010-09-08 | 2012-03-29 | The Scripps Research Institute | Reliable stabilization of n-linked polypeptide native states with enhanced aromatic sequons located in polypeptide tight turns |
| WO2012110596A1 (en) * | 2011-02-16 | 2012-08-23 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Fusion protein for the treatment of immunologic or allergic reactions |
| KR101895768B1 (ko) * | 2011-06-01 | 2018-09-07 | 시아먼 유니버시티 | 디프테리아 독소 무독성 돌연변이 씨알엠197 또는 그의 단편을 포함하는 융합 단백질 |
| US8906681B2 (en) * | 2011-08-02 | 2014-12-09 | The Scripps Research Institute | Reliable stabilization of N-linked polypeptide native states with enhanced aromatic sequons located in polypeptide tight turns |
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2017
- 2017-03-10 JP JP2018547409A patent/JP2019512233A/ja active Pending
- 2017-03-10 EP EP17764163.6A patent/EP3426785A4/en active Pending
- 2017-03-10 BR BR112018068055A patent/BR112018068055A2/pt not_active Application Discontinuation
- 2017-03-10 KR KR1020187029101A patent/KR102430891B1/ko active Active
- 2017-03-10 MX MX2018010850A patent/MX2018010850A/es unknown
- 2017-03-10 AU AU2017230792A patent/AU2017230792B2/en active Active
- 2017-03-10 US US16/083,848 patent/US10988512B2/en active Active
- 2017-03-10 CN CN202410629953.8A patent/CN118599011A/zh active Pending
- 2017-03-10 CA CA3017143A patent/CA3017143A1/en active Pending
- 2017-03-10 WO PCT/US2017/021715 patent/WO2017156356A1/en not_active Ceased
- 2017-03-10 CN CN201780025215.0A patent/CN109790545A/zh active Pending
- 2017-09-11 WO PCT/US2017/051020 patent/WO2018164712A1/en not_active Ceased
-
2018
- 2018-09-06 IL IL261660A patent/IL261660A/en unknown
- 2018-09-27 ZA ZA2018/06450A patent/ZA201806450B/en unknown
-
2022
- 2022-03-22 IL IL291586A patent/IL291586A/en unknown
- 2022-11-04 JP JP2022177061A patent/JP7532475B2/ja active Active