CN114452403A8 - 一种含有双功能免疫检查点/TGFβ抑制剂的药物组合 - Google Patents

一种含有双功能免疫检查点/TGFβ抑制剂的药物组合 Download PDF

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Publication number
CN114452403A8
CN114452403A8 CN202210121139.6A CN202210121139A CN114452403A8 CN 114452403 A8 CN114452403 A8 CN 114452403A8 CN 202210121139 A CN202210121139 A CN 202210121139A CN 114452403 A8 CN114452403 A8 CN 114452403A8
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tgf
inhibitor
immune checkpoint
pharmaceutical composition
growth factor
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CN202210121139.6A
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CN114452403A (zh
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吕容真
陈志宏
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Tongrun Biomedical Shanghai Co ltd
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Tongrun Biomedical Shanghai Co ltd
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Publication of CN114452403A publication Critical patent/CN114452403A/zh
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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Abstract

本申请涉及一种药物组合，其包含选自双功能免疫检查点/TGFβ抑制剂的第一治疗剂以及选自紫杉醇的第二治疗剂。本申请还提供了包括施用组合的治疗方法，和药物组合用于治疗肿瘤的用途。
CN202210121139.6A 2021-02-10 2022-02-09 一种含有双功能免疫检查点/TGFβ抑制剂的药物组合 Pending CN114452403A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CN202110184081 2021-02-10
CN2021101840815 2021-02-10
CN2021104105572 2021-04-13
CN202110410557 2021-04-13
CN202210099148 2022-01-27
CN202210099148X 2022-01-27

Publications (2)

Publication Number Publication Date
CN114452403A CN114452403A (zh) 2022-05-10
CN114452403A8 true CN114452403A8 (zh) 2023-01-31

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Family Applications (3)

Application Number Title Priority Date Filing Date
CN202280012531.5A Pending CN117222413A (zh) 2021-02-10 2022-02-09 治疗肿瘤的方法和组合
CN202210121154.0A Active CN115105600B (zh) 2021-02-10 2022-02-09 一种PI3Kδ/γ的药物组合及其治疗肿瘤的方法
CN202210121139.6A Pending CN114452403A (zh) 2021-02-10 2022-02-09 一种含有双功能免疫检查点/TGFβ抑制剂的药物组合

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CN202280012531.5A Pending CN117222413A (zh) 2021-02-10 2022-02-09 治疗肿瘤的方法和组合
CN202210121154.0A Active CN115105600B (zh) 2021-02-10 2022-02-09 一种PI3Kδ/γ的药物组合及其治疗肿瘤的方法

Country Status (5)

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US (1) US20240139198A1 (zh)
EP (1) EP4292596A1 (zh)
CN (3) CN117222413A (zh)
TW (1) TW202241494A (zh)
WO (1) WO2022171121A1 (zh)

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TW202241494A (zh) 2022-11-01
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