JP2006501147A5 - - Google Patents
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- Publication number
- JP2006501147A5 JP2006501147A5 JP2003587325A JP2003587325A JP2006501147A5 JP 2006501147 A5 JP2006501147 A5 JP 2006501147A5 JP 2003587325 A JP2003587325 A JP 2003587325A JP 2003587325 A JP2003587325 A JP 2003587325A JP 2006501147 A5 JP2006501147 A5 JP 2006501147A5
- Authority
- JP
- Japan
- Prior art keywords
- heat shock
- shock protein
- protein preparation
- purified
- purified heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 claims 60
- 102000002812 Heat-Shock Proteins Human genes 0.000 claims 57
- 108010004889 Heat-Shock Proteins Proteins 0.000 claims 57
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 claims 29
- 239000005483 tyrosine kinase inhibitor Substances 0.000 claims 28
- 150000004917 tyrosine kinase inhibitor derivatives Chemical class 0.000 claims 27
- 206010028980 Neoplasm Diseases 0.000 claims 25
- 201000011510 cancer Diseases 0.000 claims 21
- 238000011282 treatment Methods 0.000 claims 21
- 229960003685 imatinib mesylate Drugs 0.000 claims 18
- YLMAHDNUQAMNNX-UHFFFAOYSA-N imatinib methanesulfonate Chemical group CS(O)(=O)=O.C1CN(C)CCN1CC1=CC=C(C(=O)NC=2C=C(NC=3N=C(C=CN=3)C=3C=NC=CC=3)C(C)=CC=2)C=C1 YLMAHDNUQAMNNX-UHFFFAOYSA-N 0.000 claims 18
- 238000002560 therapeutic procedure Methods 0.000 claims 10
- 230000035939 shock Effects 0.000 claims 6
- 101100124795 Caenorhabditis elegans hsp-110 gene Proteins 0.000 claims 3
- 102000004082 Calreticulin Human genes 0.000 claims 3
- 108090000549 Calreticulin Proteins 0.000 claims 3
- 102000006303 Chaperonin 60 Human genes 0.000 claims 3
- 108010058432 Chaperonin 60 Proteins 0.000 claims 3
- 101100016370 Danio rerio hsp90a.1 gene Proteins 0.000 claims 3
- 101100285708 Dictyostelium discoideum hspD gene Proteins 0.000 claims 3
- 101100125027 Dictyostelium discoideum mhsp70 gene Proteins 0.000 claims 3
- 101150031823 HSP70 gene Proteins 0.000 claims 3
- 101100071627 Schizosaccharomyces pombe (strain 972 / ATCC 24843) swo1 gene Proteins 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 101150052825 dnaK gene Proteins 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 claims 3
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 2
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 2
- MCAHMSDENAOJFZ-UHFFFAOYSA-N Herbimycin A Natural products N1C(=O)C(C)=CC=CC(OC)C(OC(N)=O)C(C)=CC(C)C(OC)C(OC)CC(C)C(OC)C2=CC(=O)C=C1C2=O MCAHMSDENAOJFZ-UHFFFAOYSA-N 0.000 claims 2
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940045109 genistein Drugs 0.000 claims 2
- TZBJGXHYKVUXJN-UHFFFAOYSA-N genistein Natural products C1=CC(O)=CC=C1C1=COC2=CC(O)=CC(O)=C2C1=O TZBJGXHYKVUXJN-UHFFFAOYSA-N 0.000 claims 2
- 235000006539 genistein Nutrition 0.000 claims 2
- ZCOLJUOHXJRHDI-CMWLGVBASA-N genistein 7-O-beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 ZCOLJUOHXJRHDI-CMWLGVBASA-N 0.000 claims 2
- MCAHMSDENAOJFZ-BVXDHVRPSA-N herbimycin Chemical compound N1C(=O)\C(C)=C\C=C/[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@@H](OC)[C@@H](OC)C[C@H](C)[C@@H](OC)C2=CC(=O)C=C1C2=O MCAHMSDENAOJFZ-BVXDHVRPSA-N 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090000695 Cytokines Proteins 0.000 claims 1
- 206010051066 Gastrointestinal stromal tumour Diseases 0.000 claims 1
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 claims 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 208000021712 Soft tissue sarcoma Diseases 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 229960004397 cyclophosphamide Drugs 0.000 claims 1
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000011275 oncology therapy Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13196102A | 2002-04-25 | 2002-04-25 | |
| US10/322,312 US6984389B2 (en) | 2002-04-25 | 2002-12-16 | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| PCT/US2003/012802 WO2003090686A2 (en) | 2002-04-25 | 2003-04-25 | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006501147A JP2006501147A (ja) | 2006-01-12 |
| JP2006501147A5 true JP2006501147A5 (https=) | 2006-06-15 |
Family
ID=29272617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003587325A Pending JP2006501147A (ja) | 2002-04-25 | 2003-04-25 | 非ワクチン治療法の治療効果を改善するための熱ショックタンパク質の使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US20060079458A1 (https=) |
| EP (1) | EP1572083A4 (https=) |
| JP (1) | JP2006501147A (https=) |
| AU (1) | AU2003231098A1 (https=) |
| CA (1) | CA2483449A1 (https=) |
| IL (1) | IL164799A0 (https=) |
| RU (1) | RU2376029C2 (https=) |
| WO (1) | WO2003090686A2 (https=) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7449557B2 (en) | 2000-06-02 | 2008-11-11 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
| HK1079705A1 (zh) | 2001-08-20 | 2006-04-13 | University Of Connecticut Health Center | 包含用於治疗癌症及感染性疾病的热休克蛋白或α2-巨球蛋白的组合物制备方法 |
| WO2003090686A2 (en) | 2002-04-25 | 2003-11-06 | University Of Connecticut Health Center | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| WO2004074454A2 (en) * | 2003-02-20 | 2004-09-02 | University Of Connecticut Health Center | Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes |
| US7329495B2 (en) | 2004-06-09 | 2008-02-12 | Board Of Regents, The University Of Texas System | Mutations in KIT confer imatinib resistance in gastrointestinal stromal tumors |
| KR20070072543A (ko) * | 2004-09-27 | 2007-07-04 | 아스트라제네카 아베 | Ｚｄ6474 및 이마티닙을 포함하는 병합법 |
| GB0512091D0 (en) * | 2005-06-14 | 2005-07-20 | Novartis Ag | Organic compounds |
| WO2007050978A2 (en) * | 2005-10-29 | 2007-05-03 | University Of Connecticut | Methods for the elimination of pathogens and other particulate agents |
| AU2007237096C1 (en) | 2006-04-07 | 2012-12-13 | EyePoint, Inc. | Antibodies that bind human protein tyrosine phosphatase beta (HPTPbeta) and uses thereof |
| US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
| DK2257301T3 (da) | 2008-03-03 | 2014-04-28 | Univ Miami | Immunterapi baseret på allogene cancerceller. |
| AU2009262670B2 (en) | 2008-06-26 | 2013-06-20 | Zevra Denmark A/S | Use of Hsp70 as a regulator of enzymatic activity |
| MY160399A (en) | 2009-07-06 | 2017-03-15 | Aerpio Therapeutics Inc | Compounds, compositions, and methods for preventing metastasis of cancer cells |
| US9634855B2 (en) | 2010-05-13 | 2017-04-25 | Alexander Poltorak | Electronic personal interactive device that determines topics of interest using a conversational agent |
| CA2817773A1 (en) | 2010-11-30 | 2012-06-07 | Orphazyme Aps | Methods for increasing intracellular activity of hsp70 |
| AU2012323856B2 (en) | 2011-10-13 | 2017-05-25 | EyePoint, Inc. | Methods for treating Vascular Leak Syndrome and cancer |
| AU2013222414B2 (en) | 2012-02-21 | 2018-02-15 | Cytonics Corporation | Systems, compositions, and methods for transplantation |
| RU2631002C2 (ru) * | 2012-12-05 | 2017-09-15 | Тевакс Дженетикс Вэксин Ко., Лтд. | Слитые белки для применения в качестве иммуногенных усиливающих агентов для индуцирования антигенспецифического т-клеточного ответа |
| US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
| AU2014233363B2 (en) | 2013-03-15 | 2017-06-29 | EyePoint, Inc. | Compositions, formulations and methods for treating ocular diseases |
| CA2922806A1 (en) | 2013-08-28 | 2015-03-05 | Cytonics Corporation | Systems, compositions, and methods for transplantation and treating conditions utilizing a composition comprising a wild-type or a variant a2m polypeptide or portion thereof |
| WO2015038832A1 (en) | 2013-09-11 | 2015-03-19 | The Board Of Trustees Of The Leland Stanford Junior University | Arrays of accelerating structures and rapid imaging for facilitating rapid radiation therapies |
| FR3011850B1 (fr) | 2013-10-15 | 2018-04-06 | Cfl Biotech | Vaccin therapeutique contre le cancer a base de proteines de stress rendues immunogenes |
| EP3116503A4 (en) | 2014-03-14 | 2017-08-23 | Aerpio Therapeutics, Inc. | Hptp-beta inhibitors |
| EP3145516A4 (en) * | 2014-05-20 | 2018-06-13 | Kiromic, LLC | Methods and compositions for treating malignancies with dendritic cells |
| KR20160015076A (ko) | 2014-07-30 | 2016-02-12 | 삼성전자주식회사 | c-Met 저해제의 효능 예측을 위한 바이오마커 Hsp90 |
| WO2016022813A1 (en) | 2014-08-07 | 2016-02-11 | Aerpio Therapeutics, Inc. | Combination of immunotherapies with activators of tie-2 |
| KR102259232B1 (ko) | 2014-08-25 | 2021-05-31 | 삼성전자주식회사 | 항 c-Met/항 Ang2 이중 특이 항체 |
| AU2015317447B2 (en) | 2014-09-15 | 2021-02-25 | Zevra Denmark A/S | Arimoclomol formulation |
| BR112017016681A2 (pt) * | 2015-02-06 | 2018-04-10 | Heat Biologics Inc | vetor de coexpressão de vacina e moléculas coestimulatórias |
| SG10201912485PA (en) | 2015-05-13 | 2020-02-27 | Agenus Inc | Vaccines for treatment and prevention of cancer |
| ES2981607T3 (es) | 2015-09-23 | 2024-10-09 | Eyepoint Pharmaceuticals Inc | Activadores de Tie-2 para uso en el tratamiento de la presión intraocular |
| US10898476B2 (en) | 2016-04-13 | 2021-01-26 | Orphazyme A/S | Heat shock proteins and cholesterol homeostasis |
| DK3782624T3 (da) | 2016-04-29 | 2025-12-15 | Zevra Denmark As | Arimoclomol til behandling af glucocerebrosidase-associerede lidelser |
| US11666649B2 (en) | 2016-10-11 | 2023-06-06 | University Of Miami | Vectors and vaccine cells for immunity against Zika virus |
| CA3058938A1 (en) | 2017-04-04 | 2018-10-11 | Heat Biologics, Inc. | Intratumoral vaccination |
| EP3654976A1 (en) | 2017-07-21 | 2020-05-27 | Varian Medical Systems, Inc. | Methods of use of ultra-high dose rate radiation and therapeutic agents |
| MA52363A (fr) | 2018-04-26 | 2021-03-03 | Agenus Inc | Compositions peptidiques de liaison à une protéine de choc thermique (hsp) et leurs méthodes d'utilisation |
| KR20230128462A (ko) | 2020-11-19 | 2023-09-05 | 제브라 덴마크 에이/에스 | 아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5736146A (en) * | 1992-07-30 | 1998-04-07 | Yeda Research And Development Co. Ltd. | Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them |
| AU5873994A (en) | 1992-12-18 | 1994-07-19 | Duke University | Immune response modulator complex, and uses thereof |
| DK0702683T3 (da) | 1993-06-08 | 2004-02-02 | Cancer Rec Tech Ltd | 06-substituerede guaninderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf i behandling af tumorceller |
| US5750119A (en) * | 1994-01-13 | 1998-05-12 | Mount Sinai School Of Medicine Of The City University Of New York | Immunotherapeutic stress protein-peptide complexes against cancer |
| US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
| US5961979A (en) * | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
| US5869058A (en) * | 1994-05-25 | 1999-02-09 | Yeda Research And Development Co. Ltd. | Peptides used as carriers in immunogenic constructs suitable for development of synthetic vaccines |
| PT765386E (pt) | 1994-06-14 | 2015-02-06 | Univ Leland Stanford Junior | Processos para a activação in vivo de células t, através de células dendríticas pulsadas com antigénio |
| CA2178914A1 (en) * | 1994-07-27 | 1996-02-08 | Yasunori Kitano | Benzoylethylene derivative |
| WO1997006821A1 (en) | 1995-08-18 | 1997-02-27 | Sloan-Kettering Institute For Cancer Research | Heat shock protein-based vaccines and immunotherapies |
| US5935576A (en) * | 1995-09-13 | 1999-08-10 | Fordham University | Compositions and methods for the treatment and prevention of neoplastic diseases using heat shock proteins complexed with exogenous antigens |
| US5985270A (en) * | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
| US5837251A (en) * | 1995-09-13 | 1998-11-17 | Fordham University | Compositions and methods using complexes of heat shock proteins and antigenic molecules for the treatment and prevention of neoplastic diseases |
| WO1997010000A1 (en) * | 1995-09-13 | 1997-03-20 | Fordham University | Therapeutic and prophylactic methods using heat shock proteins |
| US5939098A (en) | 1996-09-19 | 1999-08-17 | Schering Corporation | Cancer treatment with temozolomide |
| US5830464A (en) * | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
| US6017540A (en) * | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
| US6150359A (en) * | 1997-08-20 | 2000-11-21 | Warner-Lambert Company | Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation |
| JPH1180131A (ja) * | 1997-09-01 | 1999-03-26 | Mitsubishi Chem Corp | エチニルピリミジン誘導体 |
| EP1027070A4 (en) * | 1997-10-31 | 2004-08-18 | Sloan Kettering Institutefor C | CONJUGATES FROM HEAT SHOCK PROTEIN-BINDING PEPTIDES |
| US7396681B1 (en) * | 1998-03-27 | 2008-07-08 | Gabriele Multhoff | Application of Hsp70 proteins |
| US6403092B1 (en) | 1998-04-01 | 2002-06-11 | Duke University | Immune response modulator alpha-2 macroglobulin complex |
| WO1999055689A1 (en) * | 1998-04-24 | 1999-11-04 | Kyowa Hakko Kogyo Co., Ltd. | Radicicol derivatives |
| GB9810423D0 (en) | 1998-05-15 | 1998-07-15 | Cancer Res Campaign Tech | Ionizing radiation or diathermy-switched gene therapy vectors and their use in antitumour therapy |
| US6251886B1 (en) | 1998-12-07 | 2001-06-26 | Schering Corporation | Methods of using temozolomide in the treatment of cancers |
| CA2367692A1 (en) | 1999-03-15 | 2000-09-21 | Introgen Therapeutics, Inc. | Dendritic cells transduced with a wild-type self gene elicit potent antitumor immune responses |
| JP2002539174A (ja) | 1999-03-17 | 2002-11-19 | エントレメッド インコーポレイテッド | 癌および血管新生関連の疾病の治療のためのｌｄｌ様受容体リガンドを使用する組成物および方法 |
| US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
| US6358954B1 (en) * | 1999-11-09 | 2002-03-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | PDGF receptor kinase inhibitory compounds, their preparation, purification and pharmaceutical compositions including same |
| JP3273777B2 (ja) * | 2000-04-07 | 2002-04-15 | 武田薬品工業株式会社 | 複素環化合物、その製造法および用途 |
| PE20011178A1 (es) * | 2000-04-07 | 2001-11-19 | Takeda Chemical Industries Ltd | Compuestos heterociclicos y su produccion |
| US7449557B2 (en) | 2000-06-02 | 2008-11-11 | University Of Connecticut Health Center | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy |
| WO2002011669A2 (en) | 2000-08-07 | 2002-02-14 | Antigenics, Llc | Compositions comprising heat shock proteins or alpha(2)macroglobulin, antigenic molecules and saponins, and methods of use thereof |
| DE60140966D1 (de) | 2000-08-29 | 2010-02-11 | Genentech Inc | Verfahren zur Verbesserung von Krebstherapie |
| WO2002022133A1 (en) | 2000-09-12 | 2002-03-21 | Virginia Commonwealth University | Promotion of adoptosis in cancer cells by co-administration of cyclin dependent kinase inhibitors and cellular differentiation agents |
| CA2422867A1 (en) | 2000-09-15 | 2002-04-25 | University Of Connecticut Health Center | Improved formulations using heat shock/stress protein-peptide complexes |
| US20020172682A1 (en) * | 2000-10-20 | 2002-11-21 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
| US7132109B1 (en) * | 2000-10-20 | 2006-11-07 | University Of Connecticut Health Center | Using heat shock proteins to increase immune response |
| RU2192884C2 (ru) * | 2000-11-09 | 2002-11-20 | Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН | Вакцина для стимуляции противоопухолевого иммунитета |
| FR2835746B1 (fr) | 2002-02-14 | 2006-05-26 | Vincience | Composition cosmetique ou pharmaceutique comprenant des hsp et des retinoides, procede de traitement et utilisation |
| CA2477417A1 (en) * | 2002-02-28 | 2003-09-04 | Antigenics Inc. | Methods and products based on oligomerization of stress proteins |
| US6984389B2 (en) | 2002-04-25 | 2006-01-10 | University Of Connecticut Health Center | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| WO2003090686A2 (en) | 2002-04-25 | 2003-11-06 | University Of Connecticut Health Center | Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality |
| WO2003092624A2 (en) | 2002-05-02 | 2003-11-13 | University Of Connecticut Health Center | Use of heat shock proteins to enhance efficacy of antibody therapeutics |
| EP1539223A2 (en) * | 2002-05-02 | 2005-06-15 | University of Connecticut Health Center | Using heat shock proteins and alpha-2-macroglobulins to increase immune response to vaccines comprising heat shock protein-peptide complexes or alpha-2-macroglobulin-peptide complexes |
| RU2324493C2 (ru) * | 2003-02-20 | 2008-05-20 | Юниверсити Оф Коннектикут Хелт Сентер | Способ применения композиций, содержащих белки теплового шока или альфа-2-макроглобулин, для лечения рака и инфекционных болезней |
| AU2005333515B2 (en) | 2004-07-09 | 2012-05-10 | Arizona Board Of Regents, Acting On Behalf Of The University Of Arizona | Wortmannin analogs and methods of using same in combination with chemotherapeutic agents |
-
2003
- 2003-04-25 WO PCT/US2003/012802 patent/WO2003090686A2/en not_active Ceased
- 2003-04-25 AU AU2003231098A patent/AU2003231098A1/en not_active Abandoned
- 2003-04-25 JP JP2003587325A patent/JP2006501147A/ja active Pending
- 2003-04-25 CA CA002483449A patent/CA2483449A1/en not_active Abandoned
- 2003-04-25 IL IL16479903A patent/IL164799A0/xx unknown
- 2003-04-25 RU RU2004134355/14A patent/RU2376029C2/ru not_active Application Discontinuation
- 2003-04-25 EP EP03724225A patent/EP1572083A4/en not_active Withdrawn
-
2005
- 2005-11-18 US US11/283,103 patent/US20060079458A1/en not_active Abandoned
-
2009
- 2009-04-06 US US12/418,724 patent/US8029808B2/en not_active Expired - Fee Related
-
2011
- 2011-09-30 US US13/250,141 patent/US8591890B2/en not_active Expired - Fee Related
- 2011-09-30 US US13/250,208 patent/US20120021997A1/en not_active Abandoned
-
2013
- 2013-10-01 US US14/043,666 patent/US9248172B2/en not_active Expired - Fee Related
-
2015
- 2015-04-27 US US14/696,846 patent/US9352019B2/en not_active Expired - Fee Related
-
2016
- 2016-05-16 US US15/155,542 patent/US20170100455A1/en not_active Abandoned
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