JP2022544175A5 - - Google Patents
Info
- Publication number
- JP2022544175A5 JP2022544175A5 JP2022507745A JP2022507745A JP2022544175A5 JP 2022544175 A5 JP2022544175 A5 JP 2022544175A5 JP 2022507745 A JP2022507745 A JP 2022507745A JP 2022507745 A JP2022507745 A JP 2022507745A JP 2022544175 A5 JP2022544175 A5 JP 2022544175A5
- Authority
- JP
- Japan
- Prior art keywords
- enteroderm
- aggregates
- aggregated
- organoids
- monolayer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025075348A JP2025128081A (ja) | 2019-08-13 | 2025-04-30 | オルガノイド組成物を作製するための改良された方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962885903P | 2019-08-13 | 2019-08-13 | |
| US62/885,903 | 2019-08-13 | ||
| PCT/US2020/045809 WO2021030373A1 (en) | 2019-08-13 | 2020-08-11 | Improved methods for making organoid compositions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025075348A Division JP2025128081A (ja) | 2019-08-13 | 2025-04-30 | オルガノイド組成物を作製するための改良された方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022544175A JP2022544175A (ja) | 2022-10-17 |
| JP2022544175A5 true JP2022544175A5 (https=) | 2023-08-18 |
| JP7676361B2 JP7676361B2 (ja) | 2025-05-14 |
Family
ID=74571192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022507745A Active JP7676361B2 (ja) | 2019-08-13 | 2020-08-11 | オルガノイド組成物を作製するための改良された方法 |
| JP2025075348A Pending JP2025128081A (ja) | 2019-08-13 | 2025-04-30 | オルガノイド組成物を作製するための改良された方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025075348A Pending JP2025128081A (ja) | 2019-08-13 | 2025-04-30 | オルガノイド組成物を作製するための改良された方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220275345A1 (https=) |
| EP (1) | EP4013853A4 (https=) |
| JP (2) | JP7676361B2 (https=) |
| CN (1) | CN114502721A (https=) |
| AU (1) | AU2020329194A1 (https=) |
| CA (1) | CA3149805A1 (https=) |
| IL (1) | IL290544A (https=) |
| WO (1) | WO2021030373A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| EP4553082A3 (en) | 2016-11-04 | 2025-08-20 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| JP7248586B2 (ja) | 2017-04-14 | 2023-03-29 | チルドレンズ ホスピタル メディカル センター | 複数ドナー幹細胞組成物およびそれを作製する方法 |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| EP4678727A3 (en) | 2018-07-26 | 2026-03-11 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US12600943B2 (en) | 2019-02-01 | 2026-04-14 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| US12497597B2 (en) | 2019-05-31 | 2025-12-16 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| WO2023278676A1 (en) * | 2021-07-02 | 2023-01-05 | Children’S Hospital Medical Center | Structurally complete organoids |
| EP4388083A4 (en) * | 2021-08-19 | 2025-07-09 | Childrens Hospital Med Ct | VASCULARIZED ORGANOIDS |
| CN114317415B (zh) * | 2022-03-07 | 2022-06-03 | 天九再生医学(天津)科技有限公司 | 人多能干细胞向多谱系大肠类器官定向分化的方法 |
| EP4562127A1 (en) * | 2022-07-29 | 2025-06-04 | Children's Hospital Medical Center | Population-scale organoid pools |
| EP4580691A1 (en) * | 2022-09-22 | 2025-07-09 | Children's Hospital Medical Center | Organoid compositions having immune cells |
| CN119968460A (zh) * | 2022-09-27 | 2025-05-09 | 庆应义塾 | 用于在不存在细胞外基质的条件下培养类器官的药物 |
| WO2024206911A2 (en) | 2023-03-30 | 2024-10-03 | Children's Hospital Medical Center | Clinical-grade organoids |
| WO2024238977A2 (en) | 2023-05-18 | 2024-11-21 | Children's Hospital Medical Center | Liver organoids with intrahepatic sympathetic nerves, and methods of use thereof |
| EP4731750A2 (en) | 2023-06-23 | 2026-04-29 | Children's Hospital Medical Center | Methods of matrix-free suspension culture |
| WO2025072803A1 (en) | 2023-09-29 | 2025-04-03 | Children's Hospital Medical Center | Ntrk2 signaling-mediated alveolar capillary injury and repair |
| WO2025212920A1 (en) | 2024-04-03 | 2025-10-09 | Children's Hospital Medical Center | Multi-zonal liver organoids |
| WO2025217202A1 (en) | 2024-04-08 | 2025-10-16 | Children's Hospital Medical Center | Bile duct organoid |
| WO2026015589A1 (en) * | 2024-07-09 | 2026-01-15 | Children's Hospital Medical Center | Pancreatic organoids and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8895300B2 (en) * | 2008-11-04 | 2014-11-25 | Viacyte, Inc. | Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof |
| WO2011119507A2 (en) * | 2010-03-25 | 2011-09-29 | International Stem Cell Corporation | Method of altering the differentiative state of a cell and compositions thereof |
| US8859286B2 (en) * | 2013-03-14 | 2014-10-14 | Viacyte, Inc. | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells |
| EP3350313B1 (en) * | 2015-09-15 | 2025-11-26 | Agency For Science, Technology And Research (A*star) | Derivation of liver organoids from human pluripotent stem cells |
| CA3027317A1 (en) * | 2016-06-14 | 2017-12-21 | Cellply S.R.L. | Screening kit and method |
| US11898166B2 (en) * | 2017-09-20 | 2024-02-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | In vitro generation of thymic organoid from human pluripotent stem cells |
-
2020
- 2020-08-11 JP JP2022507745A patent/JP7676361B2/ja active Active
- 2020-08-11 CA CA3149805A patent/CA3149805A1/en active Pending
- 2020-08-11 WO PCT/US2020/045809 patent/WO2021030373A1/en not_active Ceased
- 2020-08-11 EP EP20853468.5A patent/EP4013853A4/en active Pending
- 2020-08-11 US US17/634,148 patent/US20220275345A1/en active Pending
- 2020-08-11 CN CN202080055433.0A patent/CN114502721A/zh active Pending
- 2020-08-11 AU AU2020329194A patent/AU2020329194A1/en active Pending
-
2022
- 2022-02-10 IL IL290544A patent/IL290544A/en unknown
-
2025
- 2025-04-30 JP JP2025075348A patent/JP2025128081A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022544175A5 (https=) | ||
| Bartfeld et al. | Stem cell-derived organoids and their application for medical research and patient treatment | |
| Nikolić et al. | Human lung development: recent progress and new challenges | |
| JP7386290B2 (ja) | ヒト心室前駆細胞の生着のための遺伝子マーカー | |
| Wu et al. | Roles of airway basal stem cells in lung homeostasis and regenerative medicine | |
| Shankaran et al. | Advances in development and application of human organoids | |
| Zhang et al. | Generation of 3D human gastrointestinal organoids: principle and applications | |
| JP6738808B2 (ja) | ヒト心室前駆体細胞を単離するための細胞表面マーカーとしてのJagged1/Frizzled4の使用 | |
| Frum et al. | hPSC-derived organoids: models of human development and disease | |
| JP7225096B2 (ja) | ヒト心室前駆細胞を単離するための方法 | |
| JP7275109B2 (ja) | ニューロピリン-1(nrp1)のヒト心室前駆細胞を単離するための細胞表面マーカーとしての使用 | |
| CN113631699A (zh) | 用于生产造血谱系细胞的方法和系统 | |
| Grapin‐Botton | Three‐dimensional pancreas organogenesis models | |
| JP2017524377A (ja) | 単一細胞由来オルガノイド | |
| JP2005516616A5 (https=) | ||
| CN109777773A (zh) | 一种从造血干细胞分化产生nk细胞的方法及其培养基 | |
| CN113684182B (zh) | TGF-β抑制剂在诱导神经干细胞及类器官形成中的应用 | |
| CN113151149B (zh) | 一种诱导肺类器官的方法及实验模型的建立 | |
| JPWO2019066059A1 (ja) | 臓器オルガノイド及びその製造方法 | |
| Bhattacharyya et al. | The voyage of stem cell toward terminal differentiation: a brief overview | |
| US20090305413A1 (en) | Multipotent adult stem cells having an ability of oct4 expression derived from umbilical cord blood and method for preparing the same | |
| Oshima et al. | Regeneration of complex oral organs using 3D cell organization technology | |
| Lou et al. | Inner ear organoids: recent progress and potential applications | |
| JP5602364B2 (ja) | 幹細胞及び/又は前駆細胞の賦活剤 | |
| Mai et al. | Application of hiPSCs in tooth regeneration via cellular modulation |