JP2022544175A5 - - Google Patents

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Publication number
JP2022544175A5
JP2022544175A5 JP2022507745A JP2022507745A JP2022544175A5 JP 2022544175 A5 JP2022544175 A5 JP 2022544175A5 JP 2022507745 A JP2022507745 A JP 2022507745A JP 2022507745 A JP2022507745 A JP 2022507745A JP 2022544175 A5 JP2022544175 A5 JP 2022544175A5
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JP
Japan
Prior art keywords
enteroderm
aggregates
aggregated
organoids
monolayer
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JP2022507745A
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English (en)
Japanese (ja)
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JP7676361B2 (ja
JP2022544175A (ja
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Priority claimed from PCT/US2020/045809 external-priority patent/WO2021030373A1/en
Publication of JP2022544175A publication Critical patent/JP2022544175A/ja
Publication of JP2022544175A5 publication Critical patent/JP2022544175A5/ja
Priority to JP2025075348A priority Critical patent/JP2025128081A/ja
Application granted granted Critical
Publication of JP7676361B2 publication Critical patent/JP7676361B2/ja
Active legal-status Critical Current
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JP2022507745A 2019-08-13 2020-08-11 オルガノイド組成物を作製するための改良された方法 Active JP7676361B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025075348A JP2025128081A (ja) 2019-08-13 2025-04-30 オルガノイド組成物を作製するための改良された方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962885903P 2019-08-13 2019-08-13
US62/885,903 2019-08-13
PCT/US2020/045809 WO2021030373A1 (en) 2019-08-13 2020-08-11 Improved methods for making organoid compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025075348A Division JP2025128081A (ja) 2019-08-13 2025-04-30 オルガノイド組成物を作製するための改良された方法

Publications (3)

Publication Number Publication Date
JP2022544175A JP2022544175A (ja) 2022-10-17
JP2022544175A5 true JP2022544175A5 (https=) 2023-08-18
JP7676361B2 JP7676361B2 (ja) 2025-05-14

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ID=74571192

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JP2022507745A Active JP7676361B2 (ja) 2019-08-13 2020-08-11 オルガノイド組成物を作製するための改良された方法
JP2025075348A Pending JP2025128081A (ja) 2019-08-13 2025-04-30 オルガノイド組成物を作製するための改良された方法

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JP2025075348A Pending JP2025128081A (ja) 2019-08-13 2025-04-30 オルガノイド組成物を作製するための改良された方法

Country Status (8)

Country Link
US (1) US20220275345A1 (https=)
EP (1) EP4013853A4 (https=)
JP (2) JP7676361B2 (https=)
CN (1) CN114502721A (https=)
AU (1) AU2020329194A1 (https=)
CA (1) CA3149805A1 (https=)
IL (1) IL290544A (https=)
WO (1) WO2021030373A1 (https=)

Families Citing this family (24)

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Publication number Priority date Publication date Assignee Title
US9719068B2 (en) 2010-05-06 2017-08-01 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
SG10201801654RA (en) 2014-05-28 2018-04-27 Childrens Hospital Med Ct Methods and systems for converting precursor cells into gastric tissues through directed differentiation
EP4553082A3 (en) 2016-11-04 2025-08-20 Children's Hospital Medical Center Liver organoid compositions and methods of making and using same
JP7248586B2 (ja) 2017-04-14 2023-03-29 チルドレンズ ホスピタル メディカル センター 複数ドナー幹細胞組成物およびそれを作製する方法
EP3694603B1 (en) 2017-10-10 2026-04-08 Children's Hospital Medical Center Esophageal tissue and/or organoid compositions and methods of making same
EP3727394A4 (en) 2017-12-21 2021-09-08 Children's Hospital Medical Center DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF
EP4678727A3 (en) 2018-07-26 2026-03-11 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
CA3112026A1 (en) 2018-09-12 2020-03-19 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
US12600943B2 (en) 2019-02-01 2026-04-14 The University Of Hong Kong Innervated organoid compositions and methods of making same
US12497597B2 (en) 2019-05-31 2025-12-16 Children's Hospital Medical Center Methods of generating and expanding hematopoietic stem cells
AU2020283048A1 (en) 2019-05-31 2021-12-23 Children's Hospital Medical Center Shaped organoid compositions and methods of making same
WO2023278676A1 (en) * 2021-07-02 2023-01-05 Children’S Hospital Medical Center Structurally complete organoids
EP4388083A4 (en) * 2021-08-19 2025-07-09 Childrens Hospital Med Ct VASCULARIZED ORGANOIDS
CN114317415B (zh) * 2022-03-07 2022-06-03 天九再生医学(天津)科技有限公司 人多能干细胞向多谱系大肠类器官定向分化的方法
EP4562127A1 (en) * 2022-07-29 2025-06-04 Children's Hospital Medical Center Population-scale organoid pools
EP4580691A1 (en) * 2022-09-22 2025-07-09 Children's Hospital Medical Center Organoid compositions having immune cells
CN119968460A (zh) * 2022-09-27 2025-05-09 庆应义塾 用于在不存在细胞外基质的条件下培养类器官的药物
WO2024206911A2 (en) 2023-03-30 2024-10-03 Children's Hospital Medical Center Clinical-grade organoids
WO2024238977A2 (en) 2023-05-18 2024-11-21 Children's Hospital Medical Center Liver organoids with intrahepatic sympathetic nerves, and methods of use thereof
EP4731750A2 (en) 2023-06-23 2026-04-29 Children's Hospital Medical Center Methods of matrix-free suspension culture
WO2025072803A1 (en) 2023-09-29 2025-04-03 Children's Hospital Medical Center Ntrk2 signaling-mediated alveolar capillary injury and repair
WO2025212920A1 (en) 2024-04-03 2025-10-09 Children's Hospital Medical Center Multi-zonal liver organoids
WO2025217202A1 (en) 2024-04-08 2025-10-16 Children's Hospital Medical Center Bile duct organoid
WO2026015589A1 (en) * 2024-07-09 2026-01-15 Children's Hospital Medical Center Pancreatic organoids and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8895300B2 (en) * 2008-11-04 2014-11-25 Viacyte, Inc. Scalable primate pluripotent stem cell aggregate suspension culture and differentiation thereof
WO2011119507A2 (en) * 2010-03-25 2011-09-29 International Stem Cell Corporation Method of altering the differentiative state of a cell and compositions thereof
US8859286B2 (en) * 2013-03-14 2014-10-14 Viacyte, Inc. In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells
EP3350313B1 (en) * 2015-09-15 2025-11-26 Agency For Science, Technology And Research (A*star) Derivation of liver organoids from human pluripotent stem cells
CA3027317A1 (en) * 2016-06-14 2017-12-21 Cellply S.R.L. Screening kit and method
US11898166B2 (en) * 2017-09-20 2024-02-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services In vitro generation of thymic organoid from human pluripotent stem cells

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