JP2022543421A5 - - Google Patents

Info

Publication number
JP2022543421A5
JP2022543421A5 JP2022506949A JP2022506949A JP2022543421A5 JP 2022543421 A5 JP2022543421 A5 JP 2022543421A5 JP 2022506949 A JP2022506949 A JP 2022506949A JP 2022506949 A JP2022506949 A JP 2022506949A JP 2022543421 A5 JP2022543421 A5 JP 2022543421A5
Authority
JP
Japan
Prior art keywords
unsubstituted
substituted
alkyl
compound according
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022506949A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022543421A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/045399 external-priority patent/WO2021026450A1/en
Publication of JP2022543421A publication Critical patent/JP2022543421A/ja
Publication of JP2022543421A5 publication Critical patent/JP2022543421A5/ja
Pending legal-status Critical Current

Links

JP2022506949A 2019-08-08 2020-08-07 毒性が低減されたハイブリッドアムホテリシンb誘導体 Pending JP2022543421A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962884471P 2019-08-08 2019-08-08
US62/884,471 2019-08-08
US201962927731P 2019-10-30 2019-10-30
US62/927,731 2019-10-30
PCT/US2020/045399 WO2021026450A1 (en) 2019-08-08 2020-08-07 Hybrid amphotericin b derivatives with reduced toxicity

Publications (2)

Publication Number Publication Date
JP2022543421A JP2022543421A (ja) 2022-10-12
JP2022543421A5 true JP2022543421A5 (https=) 2023-08-08

Family

ID=74503744

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022506949A Pending JP2022543421A (ja) 2019-08-08 2020-08-07 毒性が低減されたハイブリッドアムホテリシンb誘導体

Country Status (9)

Country Link
US (1) US20230000891A1 (https=)
EP (1) EP4009984A4 (https=)
JP (1) JP2022543421A (https=)
KR (1) KR20220058547A (https=)
CN (1) CN114502173A (https=)
AU (1) AU2020325054A1 (https=)
CA (1) CA3149819A1 (https=)
IL (1) IL290290A (https=)
WO (1) WO2021026450A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0431874A1 (en) * 1989-12-08 1991-06-12 Beecham Group p.l.c. Novel compounds
US5981721A (en) * 1997-10-23 1999-11-09 Karykion Corporation Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof
KR102548341B1 (ko) * 2013-10-07 2023-06-26 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 개선된 치료 지수를 갖는 암포테리신 b 유도체
ES2749927T3 (es) * 2014-05-16 2020-03-24 Univ Illinois Derivado de anfotericina b con toxicidad reducida
WO2016014779A1 (en) * 2014-07-23 2016-01-28 The Board Of Trustees Of The University Of Illinois Antifungal polyene macrolide derivatives with reduced mammalian toxicity
WO2016061437A1 (en) * 2014-10-17 2016-04-21 The Board Of Trustees Of The University Of Illinois Scalable synthesis of reduced toxicity derivative of amphotericin b
WO2016112260A1 (en) * 2015-01-08 2016-07-14 The Board Of Trustees Of The University Of Illinois Concise synthesis of urea derivatives of amphotericin b
JP7240811B2 (ja) * 2015-04-15 2023-03-16 スファンガ セラピューティクス インコーポレイテッド アムホテリシンbの誘導体
CA3111565A1 (en) * 2018-09-07 2020-03-12 The Board Of Trustees Of The University Of Illinois Hybrid amphotericin b derivatives with reduced toxicity

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