JP2022543421A5 - - Google Patents
Info
- Publication number
- JP2022543421A5 JP2022543421A5 JP2022506949A JP2022506949A JP2022543421A5 JP 2022543421 A5 JP2022543421 A5 JP 2022543421A5 JP 2022506949 A JP2022506949 A JP 2022506949A JP 2022506949 A JP2022506949 A JP 2022506949A JP 2022543421 A5 JP2022543421 A5 JP 2022543421A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- substituted
- alkyl
- compound according
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962884471P | 2019-08-08 | 2019-08-08 | |
| US62/884,471 | 2019-08-08 | ||
| US201962927731P | 2019-10-30 | 2019-10-30 | |
| US62/927,731 | 2019-10-30 | ||
| PCT/US2020/045399 WO2021026450A1 (en) | 2019-08-08 | 2020-08-07 | Hybrid amphotericin b derivatives with reduced toxicity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022543421A JP2022543421A (ja) | 2022-10-12 |
| JP2022543421A5 true JP2022543421A5 (enExample) | 2023-08-08 |
Family
ID=74503744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506949A Pending JP2022543421A (ja) | 2019-08-08 | 2020-08-07 | 毒性が低減されたハイブリッドアムホテリシンｂ誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230000891A1 (enExample) |
| EP (1) | EP4009984A4 (enExample) |
| JP (1) | JP2022543421A (enExample) |
| KR (1) | KR20220058547A (enExample) |
| CN (1) | CN114502173A (enExample) |
| AU (1) | AU2020325054A1 (enExample) |
| CA (1) | CA3149819A1 (enExample) |
| IL (1) | IL290290A (enExample) |
| WO (1) | WO2021026450A1 (enExample) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0431874A1 (en) * | 1989-12-08 | 1991-06-12 | Beecham Group p.l.c. | Novel compounds |
| US5981721A (en) * | 1997-10-23 | 1999-11-09 | Karykion Corporation | Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof |
| KR102548341B1 (ko) * | 2013-10-07 | 2023-06-26 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 개선된 치료 지수를 갖는 암포테리신 b 유도체 |
| JP6543272B2 (ja) * | 2014-05-16 | 2019-07-10 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイＴｈｅ Ｂｏａｒｄ Ｏｆ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｉｌｌｉｎｏｉｓ | 低減された毒性を有するアンホテリシンｂ誘導体 |
| WO2016014779A1 (en) * | 2014-07-23 | 2016-01-28 | The Board Of Trustees Of The University Of Illinois | Antifungal polyene macrolide derivatives with reduced mammalian toxicity |
| ES3072651T3 (en) * | 2014-10-17 | 2026-07-03 | Univ Illinois | Scalable synthesis of reduced toxicity derivative of amphotericin b |
| JP6726192B2 (ja) * | 2015-01-08 | 2020-07-22 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイＴｈｅ Ｂｏａｒｄ Ｏｆ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｉｌｌｉｎｏｉｓ | アムホテリシンｂの尿素誘導体の簡便な合成法 |
| PT3283171T (pt) * | 2015-04-15 | 2021-07-14 | Sfunga Therapeutics Inc | Derivados de anfotericina b |
| CN113056274A (zh) * | 2018-09-07 | 2021-06-29 | 伊利诺伊大学评议会 | 具有降低的毒性的杂化两性霉素b衍生物 |
-
2020
- 2020-08-07 EP EP20851052.9A patent/EP4009984A4/en not_active Withdrawn
- 2020-08-07 AU AU2020325054A patent/AU2020325054A1/en not_active Abandoned
- 2020-08-07 US US17/633,282 patent/US20230000891A1/en not_active Abandoned
- 2020-08-07 CN CN202080070409.4A patent/CN114502173A/zh active Pending
- 2020-08-07 JP JP2022506949A patent/JP2022543421A/ja active Pending
- 2020-08-07 WO PCT/US2020/045399 patent/WO2021026450A1/en not_active Ceased
- 2020-08-07 KR KR1020227007290A patent/KR20220058547A/ko not_active Ceased
- 2020-08-07 CA CA3149819A patent/CA3149819A1/en active Pending
-
2022
- 2022-02-01 IL IL290290A patent/IL290290A/en unknown