JP2022542399A5 - - Google Patents
Info
- Publication number
- JP2022542399A5 JP2022542399A5 JP2022506196A JP2022506196A JP2022542399A5 JP 2022542399 A5 JP2022542399 A5 JP 2022542399A5 JP 2022506196 A JP2022506196 A JP 2022506196A JP 2022506196 A JP2022506196 A JP 2022506196A JP 2022542399 A5 JP2022542399 A5 JP 2022542399A5
- Authority
- JP
- Japan
- Prior art keywords
- soluble
- cells
- concentration
- interleukin
- culture medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962881311P | 2019-07-31 | 2019-07-31 | |
| US62/881,311 | 2019-07-31 | ||
| US201962932342P | 2019-11-07 | 2019-11-07 | |
| US62/932,342 | 2019-11-07 | ||
| PCT/US2020/044033 WO2021021907A1 (en) | 2019-07-31 | 2020-07-29 | Methods and compositions for enhanced expansion and cytotoxicity of natural killer cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542399A JP2022542399A (ja) | 2022-10-03 |
| JP2022542399A5 true JP2022542399A5 (enExample) | 2023-08-03 |
| JP7724765B2 JP7724765B2 (ja) | 2025-08-18 |
Family
ID=74229259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506196A Active JP7724765B2 (ja) | 2019-07-31 | 2020-07-29 | ナチュラルキラー細胞の増殖を亢進する、および細胞障害性を増強するための方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220411754A1 (enExample) |
| EP (1) | EP4003379A4 (enExample) |
| JP (1) | JP7724765B2 (enExample) |
| KR (1) | KR20220038439A (enExample) |
| CN (1) | CN114450015A (enExample) |
| AU (1) | AU2020321354A1 (enExample) |
| CA (1) | CA3144724A1 (enExample) |
| IL (1) | IL289902A (enExample) |
| MX (1) | MX2022001255A (enExample) |
| WO (1) | WO2021021907A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3143134T3 (da) | 2014-05-15 | 2021-01-04 | Nat Univ Singapore | Modificerede, naturlige dræberceller og anvendelser deraf |
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| BR112019019917A2 (pt) | 2017-03-27 | 2020-04-22 | Nat Univ Singapore | receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais |
| EP3749685A4 (en) | 2018-02-09 | 2021-12-22 | National University of Singapore | ACTIVATOR CHEMERIC RECEPTORS AND THEIR USES IN NATURAL KILLING CELL IMMUNOTHERAPY |
| JP7334985B2 (ja) | 2018-04-02 | 2023-08-29 | ナショナル ユニヴァーシティー オブ シンガポール | 免疫細胞で発現される膜結合抗サイトカイン非シグナル伝達バインダーによるヒトサイトカインの中和 |
| EP3844186A4 (en) | 2018-08-29 | 2022-08-17 | National University of Singapore | METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS |
| CA3120563A1 (en) | 2018-11-26 | 2020-06-04 | Nkarta, Inc. | Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy |
| EP3773918A4 (en) | 2019-03-05 | 2022-01-05 | Nkarta, Inc. | CD19 DIRECTED CHIMERIC ANTIGEN RECEPTORS AND THEIR USES IN IMMUNOTHERAPY |
| AU2020288829A1 (en) * | 2019-06-04 | 2021-12-02 | Nkarta, Inc. | Combinations of engineered natural killer cells and engineered T cells for immunotherapy |
| US12551530B2 (en) | 2020-08-14 | 2026-02-17 | Kite Pharma, Inc. | Immune cell function |
| IL300903A (en) * | 2020-09-02 | 2023-04-01 | Nkarta Inc | Expansion and enhanced cytotoxicity of natural killer cells and their uses |
| US20240316102A1 (en) | 2021-07-01 | 2024-09-26 | Indapta Therapeutics, Inc. | Engineered natural killer (nk) cells and related methods |
| AU2022319878A1 (en) * | 2021-07-28 | 2024-01-18 | Nkarta, Inc. | Selection of optimal cell donors and methods and compositions for enhanced expansion and cytotoxicity of donor cells |
| CN116236461B (zh) * | 2021-12-08 | 2026-03-24 | 深圳先进技术研究院 | 一种氧化还原型纳米颗粒和活细胞载体及其应用 |
| JP2025525439A (ja) | 2022-06-30 | 2025-08-05 | インダプタ セラピューティクス インコーポレイテッド | 操作されたナチュラルキラー（ｎｋ）細胞と抗体療法との組み合わせおよび関連する方法 |
| EP4649139A1 (en) * | 2023-02-01 | 2025-11-19 | Nkarta, Inc. | Methods for expanding immune cells and related compositions and uses thereof |
| WO2025150751A1 (ko) * | 2024-01-11 | 2025-07-17 | 사회복지법인 삼성생명공익재단 | Nk 세포의 활성화 및 증폭용 배양보조세포 및 이의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101684456A (zh) * | 2008-09-28 | 2010-03-31 | 江门罗森生物制药有限公司 | 一种体外培养条件下扩增人nk细胞的方法 |
| DK3143134T3 (da) * | 2014-05-15 | 2021-01-04 | Nat Univ Singapore | Modificerede, naturlige dræberceller og anvendelser deraf |
| HK1245080A1 (zh) * | 2014-10-27 | 2018-08-24 | University Of Central Florida Research Foundation, Inc. | 自然杀伤细胞的方法和组合物 |
| US20190134095A1 (en) * | 2016-05-02 | 2019-05-09 | Cerus Corporation | Compositions and methods for improved nk cell therapies |
| CN106085958A (zh) * | 2016-08-04 | 2016-11-09 | 英普乐孚生物技术(上海)有限公司 | 一种nk细胞的制备方法 |
| US10300089B2 (en) * | 2016-11-08 | 2019-05-28 | University Of Central Florida Research Foundation, Inc. | Methods for high scale therapeutic production of memory NK cells |
| CA3056591A1 (en) * | 2017-03-27 | 2018-10-04 | National University Of Singapore | Stimulatory cell lines for ex vivo expansion and activation of natural killer cells |
-
2020
- 2020-07-29 JP JP2022506196A patent/JP7724765B2/ja active Active
- 2020-07-29 US US17/628,105 patent/US20220411754A1/en active Pending
- 2020-07-29 MX MX2022001255A patent/MX2022001255A/es unknown
- 2020-07-29 AU AU2020321354A patent/AU2020321354A1/en active Pending
- 2020-07-29 CN CN202080068418.XA patent/CN114450015A/zh active Pending
- 2020-07-29 CA CA3144724A patent/CA3144724A1/en active Pending
- 2020-07-29 EP EP20848600.1A patent/EP4003379A4/en active Pending
- 2020-07-29 WO PCT/US2020/044033 patent/WO2021021907A1/en not_active Ceased
- 2020-07-29 KR KR1020227005973A patent/KR20220038439A/ko active Pending
-
2022
- 2022-01-16 IL IL289902A patent/IL289902A/en unknown
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