JP2022541254A5 - - Google Patents
Info
- Publication number
- JP2022541254A5 JP2022541254A5 JP2022502926A JP2022502926A JP2022541254A5 JP 2022541254 A5 JP2022541254 A5 JP 2022541254A5 JP 2022502926 A JP2022502926 A JP 2022502926A JP 2022502926 A JP2022502926 A JP 2022502926A JP 2022541254 A5 JP2022541254 A5 JP 2022541254A5
- Authority
- JP
- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875402P | 2019-07-17 | 2019-07-17 | |
| US62/875,402 | 2019-07-17 | ||
| PCT/IB2020/000634 WO2021009566A1 (en) | 2019-07-17 | 2020-07-16 | N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,5,6,7-tetrahydrobenzofuran -2-sulfonamide derivatives and related compounds as nlpr3 modulators for the treatment of multiple sclerosis (ms) |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022541254A JP2022541254A (ja) | 2022-09-22 |
| JP2022541254A5 true JP2022541254A5 (https=) | 2023-07-25 |
| JPWO2021009566A5 JPWO2021009566A5 (https=) | 2023-07-25 |
| JP7723652B2 JP7723652B2 (ja) | 2025-08-14 |
Family
ID=72145418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502926A Active JP7723652B2 (ja) | 2019-07-17 | 2020-07-16 | 多発性硬化症（ＭＳ）の治療のためのＮＬＰＲ３モジュレーターとしてのＮ－（（１，２，３，５，６，７－ヘキサヒドロ－ｓ－インダセン－４－イル）カルバモイル）－４，５，６，７－テトラヒドロベンゾフラン－２－スルホンアミド誘導体および関連化合物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12466800B2 (https=) |
| EP (1) | EP3999496B1 (https=) |
| JP (1) | JP7723652B2 (https=) |
| KR (1) | KR20220064364A (https=) |
| CN (1) | CN114555571B (https=) |
| AU (1) | AU2020312800B2 (https=) |
| BR (1) | BR112022000878A2 (https=) |
| CA (1) | CA3151865A1 (https=) |
| IL (1) | IL289885B2 (https=) |
| MX (1) | MX2022000646A (https=) |
| WO (1) | WO2021009566A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220064364A (ko) | 2019-07-17 | 2022-05-18 | 조마젠 바이오사이언시즈 엘티디 | 다발성 경화증(ms)의 치료를 위한 nlpr3 조절제로서의 n-((1,2,3,5,6,7-헥사하이드로-s-인다센-4-일)카바모일)-4,5,6,7-테트라하이드로벤조푸란-2-설폰아미드 유도체 및 관련 화합물 |
| EP3999179A1 (en) | 2019-07-17 | 2022-05-25 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| PH12022552447A1 (en) | 2020-03-16 | 2024-01-03 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| WO2023077046A1 (en) | 2021-10-29 | 2023-05-04 | Arcus Biosciences, Inc. | Inhibitors of hif-2alpha and methods of use thereof |
| WO2023116812A1 (zh) * | 2021-12-22 | 2023-06-29 | 瑞石生物医药有限公司 | 一种磺酰脲类化合物 |
| WO2024010772A1 (en) * | 2022-07-06 | 2024-01-11 | Kodiak Sciences Inc. | Nlrp3 inhibitors |
| CN116283533B (zh) * | 2023-02-17 | 2024-02-23 | 华南理工大学 | 具有nlrp3抑制活性的鸡脚参酮a及其衍生物与应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3259253T1 (sl) * | 2015-02-16 | 2020-07-31 | The University Of Queensland | Sulfonilsečnine in sorodne spojine ter njihova uporaba |
| JP2019512009A (ja) | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| US11339136B2 (en) | 2016-04-18 | 2022-05-24 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| US11447460B2 (en) | 2016-04-18 | 2022-09-20 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| EP3571187B1 (en) | 2017-01-23 | 2023-11-22 | Genentech, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
| JP7072586B2 (ja) * | 2017-05-24 | 2022-05-20 | ザ ユニバーシティ オブ クィーンズランド | 新規な化合物及び使用 |
| NZ760129A (en) | 2017-07-07 | 2025-12-19 | Inflazome Ltd | Novel sulfonamide carboxamide compounds |
| MA49903A (fr) | 2017-08-15 | 2020-06-24 | Inflazome Ltd | Sulfonylureés et sulfonylthioureés en tant qu'inhibiteurs de nlrp3 |
| UY37848A (es) | 2017-08-15 | 2019-03-29 | Inflazome Ltd | Sulfonilureas y sulfoniltioureas útiles como inhibidores de nlrp3 |
| EP3668601A1 (en) | 2017-08-15 | 2020-06-24 | Inflazome Limited | Novel sulfonamide carboxamide compounds |
| WO2019079119A1 (en) | 2017-10-17 | 2019-04-25 | IFM Tre, Inc. | SULFONAMIDES AND ASSOCIATED COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH NLRP ACTIVITY |
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| CA3105521A1 (en) | 2018-07-20 | 2020-01-23 | F. Hoffmann-La Roche Ag | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| JP2022505525A (ja) * | 2018-10-24 | 2022-01-14 | ノバルティス アーゲー | Ｎｌｒｐ活性に関連する状態を治療するための化合物及び組成物 |
| KR20220064364A (ko) | 2019-07-17 | 2022-05-18 | 조마젠 바이오사이언시즈 엘티디 | 다발성 경화증(ms)의 치료를 위한 nlpr3 조절제로서의 n-((1,2,3,5,6,7-헥사하이드로-s-인다센-4-일)카바모일)-4,5,6,7-테트라하이드로벤조푸란-2-설폰아미드 유도체 및 관련 화합물 |
| EP3999179A1 (en) | 2019-07-17 | 2022-05-25 | Zomagen Biosciences Ltd | Nlrp3 modulators |
| PY2121402A (es) | 2020-03-16 | 2022-08-09 | Norvatis Ag | Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead |
| CL2022002490A1 (es) | 2020-03-16 | 2023-05-05 | Novartis Ag | Derivados de biarilo como inhibidores de la interacción proteína-proteína de yap/taz-tead |
| PH12022552447A1 (en) | 2020-03-16 | 2024-01-03 | Zomagen Biosciences Ltd | Nlrp3 modulators |
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2020
- 2020-07-16 KR KR1020227005288A patent/KR20220064364A/ko active Pending
- 2020-07-16 AU AU2020312800A patent/AU2020312800B2/en active Active
- 2020-07-16 CA CA3151865A patent/CA3151865A1/en active Pending
- 2020-07-16 US US17/627,082 patent/US12466800B2/en active Active
- 2020-07-16 EP EP20757941.8A patent/EP3999496B1/en active Active
- 2020-07-16 CN CN202080064480.1A patent/CN114555571B/zh active Active
- 2020-07-16 JP JP2022502926A patent/JP7723652B2/ja active Active
- 2020-07-16 WO PCT/IB2020/000634 patent/WO2021009566A1/en not_active Ceased
- 2020-07-16 MX MX2022000646A patent/MX2022000646A/es unknown
- 2020-07-16 IL IL289885A patent/IL289885B2/en unknown
- 2020-07-16 BR BR112022000878A patent/BR112022000878A2/pt unknown