JP2023504415A5 - - Google Patents

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Publication number
JP2023504415A5
JP2023504415A5 JP2022531534A JP2022531534A JP2023504415A5 JP 2023504415 A5 JP2023504415 A5 JP 2023504415A5 JP 2022531534 A JP2022531534 A JP 2022531534A JP 2022531534 A JP2022531534 A JP 2022531534A JP 2023504415 A5 JP2023504415 A5 JP 2023504415A5
Authority
JP
Japan
Prior art keywords
isopropylphenyl
pulmonary fibrosis
azetidine
carbamoyl
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022531534A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023504415A (ja
JP7665619B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/084401 external-priority patent/WO2021110805A1/en
Publication of JP2023504415A publication Critical patent/JP2023504415A/ja
Publication of JP2023504415A5 publication Critical patent/JP2023504415A5/ja
Application granted granted Critical
Publication of JP7665619B2 publication Critical patent/JP7665619B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022531534A 2019-12-04 2020-12-03 線維性疾患の治療に使用するためのアゼチジンlpa1受容体アンタゴニストのピルフェニドン及び/又はニンテダニブとの合剤 Active JP7665619B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2019/083757 2019-12-04
EP2019083757 2019-12-04
PCT/EP2020/084401 WO2021110805A1 (en) 2019-12-04 2020-12-03 Combination of an azetidine lpa1 receptor antagonist with pirfenidone and/or nintedanib for use in the treatment of fibrotic diseases

Publications (3)

Publication Number Publication Date
JP2023504415A JP2023504415A (ja) 2023-02-03
JP2023504415A5 true JP2023504415A5 (https=) 2023-12-12
JP7665619B2 JP7665619B2 (ja) 2025-04-21

Family

ID=76221504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022531534A Active JP7665619B2 (ja) 2019-12-04 2020-12-03 線維性疾患の治療に使用するためのアゼチジンlpa1受容体アンタゴニストのピルフェニドン及び/又はニンテダニブとの合剤

Country Status (14)

Country Link
US (1) US12539294B2 (https=)
EP (1) EP4069227A1 (https=)
JP (1) JP7665619B2 (https=)
KR (1) KR20220109439A (https=)
CN (1) CN114761001A (https=)
AU (1) AU2020397207B2 (https=)
BR (1) BR112022010891A2 (https=)
CA (1) CA3160410A1 (https=)
CL (1) CL2022001439A1 (https=)
IL (1) IL293474A (https=)
MX (1) MX2022006736A (https=)
PH (1) PH12022551359A1 (https=)
TW (1) TWI895300B (https=)
WO (1) WO2021110805A1 (https=)

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TWI843503B (zh) 2020-06-03 2024-05-21 美商基利科學股份有限公司 Lpa受體拮抗劑及其用途
EP4161936A1 (en) 2020-06-03 2023-04-12 Gilead Sciences, Inc. Lpa receptor antagonists and uses thereof
WO2022240879A1 (en) 2021-05-11 2022-11-17 Gilead Sciences, Inc. Lpa receptor antagonists and uses thereof
KR20240007233A (ko) 2021-05-13 2024-01-16 길리애드 사이언시즈, 인코포레이티드 Lpa 수용체 길항제 및 이의 용도
WO2023107938A1 (en) 2021-12-08 2023-06-15 Gilead Sciences, Inc. Lpa receptor antagonists and uses thereof
JP2025511066A (ja) * 2022-03-31 2025-04-15 ピュアテック・エル・ワイ・ティ・100・インコーポレイテッド デューピルフェニドンにより間質性肺疾患ならびに他の線維化介在性肺疾患及び障害を治療する方法
CN120379666A (zh) * 2022-12-23 2025-07-25 百时美施贵宝公司 用于治疗间质性肺病的lpa1拮抗剂
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