JP2022538926A5 - - Google Patents
Info
- Publication number
- JP2022538926A5 JP2022538926A5 JP2022500544A JP2022500544A JP2022538926A5 JP 2022538926 A5 JP2022538926 A5 JP 2022538926A5 JP 2022500544 A JP2022500544 A JP 2022500544A JP 2022500544 A JP2022500544 A JP 2022500544A JP 2022538926 A5 JP2022538926 A5 JP 2022538926A5
- Authority
- JP
- Japan
- Prior art keywords
- poly
- seq
- antibody
- ran
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024185014A JP2025026843A (ja) | 2019-07-05 | 2024-10-21 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962871031P | 2019-07-05 | 2019-07-05 | |
| US62/871,031 | 2019-07-05 | ||
| US202063025096P | 2020-05-14 | 2020-05-14 | |
| US63/025,096 | 2020-05-14 | ||
| PCT/US2020/040725 WO2021007110A1 (en) | 2019-07-05 | 2020-07-02 | Methods for treating ran protein-associated neurological diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024185014A Division JP2025026843A (ja) | 2019-07-05 | 2024-10-21 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022538926A JP2022538926A (ja) | 2022-09-06 |
| JP2022538926A5 true JP2022538926A5 (https=) | 2023-07-10 |
| JP7579589B2 JP7579589B2 (ja) | 2024-11-08 |
Family
ID=74114201
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500544A Active JP7579589B2 (ja) | 2019-07-05 | 2020-07-02 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
| JP2024185014A Pending JP2025026843A (ja) | 2019-07-05 | 2024-10-21 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024185014A Pending JP2025026843A (ja) | 2019-07-05 | 2024-10-21 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220267776A1 (https=) |
| EP (1) | EP3994159A4 (https=) |
| JP (2) | JP7579589B2 (https=) |
| AU (1) | AU2020310843A1 (https=) |
| CA (1) | CA3145291A1 (https=) |
| WO (1) | WO2021007110A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10509045B2 (en) | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| WO2018195110A1 (en) | 2017-04-17 | 2018-10-25 | University Of Florida Research Foundation, Incorporated | Regolation of ran translation by pkr and eif2a-p pathways |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| EP3688020A4 (en) | 2017-09-25 | 2021-07-14 | University of Florida Research Foundation, Incorporated | IMMUNOASSAYS FOR DETECTION OF RAN PROTEINS |
| AU2018342105B2 (en) | 2017-09-26 | 2023-11-16 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| WO2021055880A1 (en) | 2019-09-20 | 2021-03-25 | University Of Florida Researchfoundation, Incorporated | Detection of antibodies against ran proteins from serum and tissue lysates |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| EP4427049A4 (en) * | 2021-11-01 | 2025-08-20 | Univ Florida | POLY-GA PROTEINS IN ALZHEIMER'S DISEASE |
| EP4440560A1 (en) | 2021-12-01 | 2024-10-09 | University Of Florida Research Foundation, Incorporated | Small molecule inhibitors of repeat associated non-aug (ran) translation and combination therapies |
| WO2024097756A1 (en) * | 2022-11-01 | 2024-05-10 | University Of Florida Research Foundation, Incorporated | Interrupted ran proteins in disease |
| WO2024173816A1 (en) * | 2023-02-17 | 2024-08-22 | The University Of North Carolina At Chapel Hill | Methods of detecting telomere-encoded dipeptide repeat proteins and therapeutic applications |
| CN116693621B (zh) * | 2023-03-02 | 2023-11-14 | 东北农业大学 | 抑制革兰氏阴性菌的窄谱抗菌肽pc及其制备方法和应用 |
| WO2025019730A1 (en) * | 2023-07-20 | 2025-01-23 | University Of Florida Research Foundation, Incorporated | Engineered ga antibodies for therapy development |
| WO2025128551A1 (en) * | 2023-12-11 | 2025-06-19 | University Of Florida Research Foundation, Incorporated | Aav-based anti-ga therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014114660A1 (en) * | 2013-01-22 | 2014-07-31 | Deutsches Zentrum Für Neurodegenerative Erkrankungen E.V. (Dzne) | Dipeptide-repeat proteins as therapeutic target in neurodegenerative diseases with hexanucleotide repeat expansion |
| WO2014159247A1 (en) * | 2013-03-14 | 2014-10-02 | University Of Florida Research Foundation, Inc. | Di-amino acid repeat-containing proteins associated with als |
| CA2955086A1 (en) * | 2014-08-08 | 2016-02-11 | Alector Llc | Anti-trem2 antibodies and methods of use thereof |
| JP6432023B2 (ja) * | 2014-12-02 | 2018-12-05 | 国立大学法人 東京医科歯科大学 | 脊髄小脳失調症３１型（ｓｃａ３１）治療剤 |
| US10509045B2 (en) * | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) * | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| EP3664816A4 (en) * | 2017-08-08 | 2021-05-19 | Wave Life Sciences Ltd. | OLIGONUCLEOTIDE COMPOSITIONS AND RELATED PROCESSES |
| EP3688020A4 (en) * | 2017-09-25 | 2021-07-14 | University of Florida Research Foundation, Incorporated | IMMUNOASSAYS FOR DETECTION OF RAN PROTEINS |
| AU2018342105B2 (en) * | 2017-09-26 | 2023-11-16 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
-
2020
- 2020-07-02 EP EP20836437.2A patent/EP3994159A4/en active Pending
- 2020-07-02 WO PCT/US2020/040725 patent/WO2021007110A1/en not_active Ceased
- 2020-07-02 JP JP2022500544A patent/JP7579589B2/ja active Active
- 2020-07-02 AU AU2020310843A patent/AU2020310843A1/en active Pending
- 2020-07-02 CA CA3145291A patent/CA3145291A1/en active Pending
- 2020-07-02 US US17/624,700 patent/US20220267776A1/en active Pending
-
2024
- 2024-10-21 JP JP2024185014A patent/JP2025026843A/ja active Pending
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