JP2025026843A5 - - Google Patents
Info
- Publication number
- JP2025026843A5 JP2025026843A5 JP2024185014A JP2024185014A JP2025026843A5 JP 2025026843 A5 JP2025026843 A5 JP 2025026843A5 JP 2024185014 A JP2024185014 A JP 2024185014A JP 2024185014 A JP2024185014 A JP 2024185014A JP 2025026843 A5 JP2025026843 A5 JP 2025026843A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antibody
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962871031P | 2019-07-05 | 2019-07-05 | |
| US62/871,031 | 2019-07-05 | ||
| US202063025096P | 2020-05-14 | 2020-05-14 | |
| US63/025,096 | 2020-05-14 | ||
| JP2022500544A JP7579589B2 (ja) | 2019-07-05 | 2020-07-02 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
| PCT/US2020/040725 WO2021007110A1 (en) | 2019-07-05 | 2020-07-02 | Methods for treating ran protein-associated neurological diseases |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500544A Division JP7579589B2 (ja) | 2019-07-05 | 2020-07-02 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025026843A JP2025026843A (ja) | 2025-02-26 |
| JP2025026843A5 true JP2025026843A5 (https=) | 2025-09-29 |
Family
ID=74114201
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500544A Active JP7579589B2 (ja) | 2019-07-05 | 2020-07-02 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
| JP2024185014A Pending JP2025026843A (ja) | 2019-07-05 | 2024-10-21 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022500544A Active JP7579589B2 (ja) | 2019-07-05 | 2020-07-02 | Ｒａｎタンパク質関連神経学的疾患を処置するための方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20220267776A1 (https=) |
| EP (1) | EP3994159A4 (https=) |
| JP (2) | JP7579589B2 (https=) |
| AU (1) | AU2020310843A1 (https=) |
| CA (1) | CA3145291A1 (https=) |
| WO (1) | WO2021007110A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10509045B2 (en) | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| WO2018195110A1 (en) | 2017-04-17 | 2018-10-25 | University Of Florida Research Foundation, Incorporated | Regolation of ran translation by pkr and eif2a-p pathways |
| AU2018308088B2 (en) | 2017-07-25 | 2025-05-29 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| JP2020535448A (ja) | 2017-09-25 | 2020-12-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | Ｒａｎタンパク質の検出のための免役アッセイ |
| US11903910B2 (en) | 2017-09-26 | 2024-02-20 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders |
| AU2020214796A1 (en) | 2019-01-30 | 2021-07-29 | Truebinding, Inc. | Anti-Gal3 antibodies and uses thereof |
| WO2021055880A1 (en) | 2019-09-20 | 2021-03-25 | University Of Florida Researchfoundation, Incorporated | Detection of antibodies against ran proteins from serum and tissue lysates |
| WO2021242776A2 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
| WO2023077153A1 (en) * | 2021-11-01 | 2023-05-04 | University Of Florida Research Foundation, Incorporated | Poly-ga proteins in alzheimer's disease |
| WO2023102111A1 (en) | 2021-12-01 | 2023-06-08 | University Of Florida Research Foundation, Incorporated | Small molecule inhibitors of repeat associated non-aug (ran) translation and combination therapies |
| AU2023373378A1 (en) * | 2022-11-01 | 2025-04-24 | University Of Florida Research Foundation, Incorporated | Interrupted ran proteins in disease |
| WO2024173816A1 (en) * | 2023-02-17 | 2024-08-22 | The University Of North Carolina At Chapel Hill | Methods of detecting telomere-encoded dipeptide repeat proteins and therapeutic applications |
| CN116693621B (zh) * | 2023-03-02 | 2023-11-14 | 东北农业大学 | 抑制革兰氏阴性菌的窄谱抗菌肽pc及其制备方法和应用 |
| WO2025019730A1 (en) * | 2023-07-20 | 2025-01-23 | University Of Florida Research Foundation, Incorporated | Engineered ga antibodies for therapy development |
| WO2025128551A1 (en) * | 2023-12-11 | 2025-06-19 | University Of Florida Research Foundation, Incorporated | Aav-based anti-ga therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2948777T (pt) * | 2013-01-22 | 2019-09-26 | Deutsches Zentrum Fuer Neurodegenerative Erkrankungen E V | Proteínas de repetição por dipeptídeos como alvo terapêutico em doenças neurodegenerativas com expansão de hexanucleotídico repetido |
| WO2014159247A1 (en) * | 2013-03-14 | 2014-10-02 | University Of Florida Research Foundation, Inc. | Di-amino acid repeat-containing proteins associated with als |
| EP3177322A4 (en) * | 2014-08-08 | 2018-07-18 | Alector LLC | Anti-trem2 antibodies and methods of use thereof |
| JP6432023B2 (ja) * | 2014-12-02 | 2018-12-05 | 国立大学法人 東京医科歯科大学 | 脊髄小脳失調症３１型（ｓｃａ３１）治療剤 |
| US10509045B2 (en) * | 2015-05-29 | 2019-12-17 | University Of Florida Research Foundation, Incorporated | Methods for diagnosing Huntington's disease |
| US10940161B2 (en) * | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
| TW201920672A (zh) * | 2017-08-08 | 2019-06-01 | 新加坡商波濤生命科學有限公司 | 寡核苷酸組合物及其使用方法 |
| JP2020535448A (ja) * | 2017-09-25 | 2020-12-03 | ユニバーシティー オブ フロリダ リサーチ ファンデーション， インク． | Ｒａｎタンパク質の検出のための免役アッセイ |
| US11903910B2 (en) * | 2017-09-26 | 2024-02-20 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce RAN protein levels in the treatment of neurological disorders |
-
2020
- 2020-07-02 US US17/624,700 patent/US20220267776A1/en active Pending
- 2020-07-02 WO PCT/US2020/040725 patent/WO2021007110A1/en not_active Ceased
- 2020-07-02 CA CA3145291A patent/CA3145291A1/en active Pending
- 2020-07-02 AU AU2020310843A patent/AU2020310843A1/en active Pending
- 2020-07-02 EP EP20836437.2A patent/EP3994159A4/en active Pending
- 2020-07-02 JP JP2022500544A patent/JP7579589B2/ja active Active
-
2024
- 2024-10-21 JP JP2024185014A patent/JP2025026843A/ja active Pending
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