JP2020519308A5 - - Google Patents

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Publication number
JP2020519308A5
JP2020519308A5 JP2020512919A JP2020512919A JP2020519308A5 JP 2020519308 A5 JP2020519308 A5 JP 2020519308A5 JP 2020512919 A JP2020512919 A JP 2020512919A JP 2020512919 A JP2020512919 A JP 2020512919A JP 2020519308 A5 JP2020519308 A5 JP 2020519308A5
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JP
Japan
Prior art keywords
antigen
antibody
binding fragment
seq
amino acid
Prior art date
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Granted
Application number
JP2020512919A
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English (en)
Japanese (ja)
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JP7118135B2 (ja
JP2020519308A (ja
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Priority claimed from GBGB1707561.5A external-priority patent/GB201707561D0/en
Application filed filed Critical
Publication of JP2020519308A publication Critical patent/JP2020519308A/ja
Publication of JP2020519308A5 publication Critical patent/JP2020519308A5/ja
Priority to JP2022122483A priority Critical patent/JP2022169549A/ja
Application granted granted Critical
Publication of JP7118135B2 publication Critical patent/JP7118135B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020512919A 2017-05-11 2018-05-11 ＧＡＲＰ－ＴＧＦ－β抗体 Active JP7118135B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022122483A JP2022169549A (ja) 2017-05-11 2022-08-01 ＧＡＲＰ－ＴＧＦ－β抗体

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1707561.5A GB201707561D0 (en) 2017-05-11 2017-05-11 GARP-TGF-beta antibodies
GB1707561.5 2017-05-11
PCT/EP2018/062251 WO2018206790A1 (en) 2017-05-11 2018-05-11 GARP-TGF-β ANTIBODIES

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022122483A Division JP2022169549A (ja) 2017-05-11 2022-08-01 ＧＡＲＰ－ＴＧＦ－β抗体

Publications (3)

Publication Number Publication Date
JP2020519308A JP2020519308A (ja) 2020-07-02
JP2020519308A5 true JP2020519308A5 (https=) 2022-01-25
JP7118135B2 JP7118135B2 (ja) 2022-08-15

Family

ID=59201573

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020512919A Active JP7118135B2 (ja) 2017-05-11 2018-05-11 ＧＡＲＰ－ＴＧＦ－β抗体
JP2022122483A Withdrawn JP2022169549A (ja) 2017-05-11 2022-08-01 ＧＡＲＰ－ＴＧＦ－β抗体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022122483A Withdrawn JP2022169549A (ja) 2017-05-11 2022-08-01 ＧＡＲＰ－ＴＧＦ－β抗体

Country Status (35)

Country Link
US (4) US10479829B2 (https=)
EP (3) EP3606961B8 (https=)
JP (2) JP7118135B2 (https=)
KR (2) KR102664663B1 (https=)
CN (1) CN110945027B (https=)
AU (2) AU2018265241B2 (https=)
BR (1) BR112019023735A8 (https=)
CA (1) CA3061841C (https=)
CL (1) CL2019003211A1 (https=)
CO (1) CO2019013669A2 (https=)
CR (1) CR20190561A (https=)
CY (1) CY1125674T1 (https=)
DK (1) DK3606961T3 (https=)
DO (1) DOP2019000285A (https=)
EC (1) ECSP19087742A (https=)
ES (1) ES2921015T3 (https=)
GB (1) GB201707561D0 (https=)
HR (1) HRP20220787T1 (https=)
HU (1) HUE059237T2 (https=)
IL (2) IL305613A (https=)
LT (1) LT3606961T (https=)
MX (1) MX385670B (https=)
MY (1) MY199335A (https=)
NZ (1) NZ758647A (https=)
PE (1) PE20200618A1 (https=)
PH (1) PH12019502526A1 (https=)
PL (1) PL3606961T3 (https=)
PT (1) PT3606961T (https=)
RS (1) RS63361B1 (https=)
RU (1) RU2767784C2 (https=)
SG (1) SG10201914130VA (https=)
SI (1) SI3606961T1 (https=)
SM (1) SMT202200284T1 (https=)
UA (1) UA125534C2 (https=)
WO (1) WO2018206790A1 (https=)

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EP3960855A1 (en) * 2001-12-28 2022-03-02 Chugai Seiyaku Kabushiki Kaisha Method for stabilizing proteins
EP3436480A4 (en) * 2016-03-30 2019-11-27 Musc Foundation for Research Development METHOD FOR THE TREATMENT AND DIAGNOSIS OF CANCER BY TARGETING GLYCOPROTEIN A REPETITION PREDOMINANT (GARP) AND FOR EFFECTIVE IMMUNOTHERAPY ALONE OR IN COMBINATION
CN114729370B (zh) 2019-08-28 2025-03-21 中外制药株式会社 跨物种抗潜伏TGF-β1抗体和使用方法
US20240190961A1 (en) 2019-10-25 2024-06-13 Daiichi Sankyo Company, Limited Combination of anti-garp antibody and immunomodulator
TW202135862A (zh) * 2020-01-11 2021-10-01 美商供石公司 TGFβ抑制劑及其用途
WO2021167703A1 (en) 2020-02-19 2021-08-26 Nammi Therapeutics, Inc. Formulated and/or co-formulated liposome compositions containing tgfb antagonist prodrugs useful in the treatment of cancer and methods thereof
US20230192867A1 (en) * 2020-05-15 2023-06-22 Bristol-Myers Squibb Company Antibodies to garp
WO2022103705A1 (en) * 2020-11-11 2022-05-19 Versapeutics Inc. Antibody variants against wnt receptor ryk
WO2022116877A1 (en) 2020-12-02 2022-06-09 Shanghai Henlius Biotech, Inc. ANTI-GARP/TGFβ ANTIBODIES AND METHODS OF USE
BR112023014319A2 (pt) * 2021-01-18 2023-09-26 Jiangxi Jemincare Group Co Ltd Anticorpo contra a proteína garp e aplicação do mesmo
US20260013513A1 (en) 2022-05-18 2026-01-15 Vestaron Corporation Pesticidal actx peptide variants
JP2025526336A (ja) 2022-07-22 2025-08-13 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Ｔ細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのｇａｒｐ
JP2025524957A (ja) 2022-07-29 2025-08-01 アッヴィ・バイオセラピューティクス・インコーポレイテッド 抗ＧＡＲＰ－ＴＧＦ－β１／ＰＤ－１併用療法
TW202434643A (zh) 2023-01-09 2024-09-01 大陸商北京拓界生物醫藥科技有限公司 ＴＧＦβ１結合分子、ＧＡＲＰ－ＴＧＦβ１結合分子及其醫藥用途
CN118829657A (zh) * 2023-02-06 2024-10-22 贝达药业股份有限公司 多特异性抗体及其应用

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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5892019A (en) 1987-07-15 1999-04-06 The United States Of America, As Represented By The Department Of Health And Human Services Production of a single-gene-encoded immunoglobulin
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
ATE207080T1 (de) 1991-11-25 2001-11-15 Enzon Inc Multivalente antigen-bindende proteine
NZ298145A (en) 1994-12-29 1998-08-26 Yamanouchi Pharma Co Ltd Monoclonal antibodies having inhibitory effect on type ii phospholipase a2, proteins forming part thereof, cells producing them, dna encoding them, recombinant vector comprising the dna and medicament
US7709610B2 (en) 2003-05-08 2010-05-04 Facet Biotech Corporation Therapeutic use of anti-CS1 antibodies
ES2304069B1 (es) * 2003-08-22 2009-08-12 Proyecto De Biomedicina Cima, S.L. Peptidos con capacidad de unirse al factor transformante de crecimiento beta 1 (tgf-b1).
US20070048785A1 (en) 2004-06-09 2007-03-01 Lin Laura L Anti-IL-13 antibodies and complexes
WO2006103639A2 (en) 2005-03-31 2006-10-05 Case Western Reserve University Methods and reagents for identifying/isolating t regulatory (treg) cells and for treating individuals
US20110086367A1 (en) 2006-04-03 2011-04-14 Medizinische Hochschule Hannover Pharmaceuticals for influencing the reaction of the human immune system
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EP2832747A1 (en) * 2013-08-01 2015-02-04 Université Catholique de Louvain Anti-GARP protein and uses thereof
ES2860952T3 (es) * 2013-08-01 2021-10-05 Univ Catholique Louvain Proteína anti-garp y usos de la misma
WO2016125017A1 (en) * 2015-02-03 2016-08-11 Universite Catholique De Louvain Anti-garp protein and uses thereof
DK3354729T5 (da) * 2015-09-24 2024-09-30 Daiichi Sankyo Co Ltd Anti-garp-antistof
CN110049773A (zh) * 2016-07-14 2019-07-23 供石公司 TGFβ抗体、方法和用途

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