JP2022535745A5 - - Google Patents
Info
- Publication number
- JP2022535745A5 JP2022535745A5 JP2021570364A JP2021570364A JP2022535745A5 JP 2022535745 A5 JP2022535745 A5 JP 2022535745A5 JP 2021570364 A JP2021570364 A JP 2021570364A JP 2021570364 A JP2021570364 A JP 2021570364A JP 2022535745 A5 JP2022535745 A5 JP 2022535745A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- percent
- codon
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962855506P | 2019-05-31 | 2019-05-31 | |
| US62/855,506 | 2019-05-31 | ||
| PCT/US2020/035584 WO2020243717A1 (en) | 2019-05-31 | 2020-06-01 | Optimized phenylalanine hydroxylase expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022535745A JP2022535745A (ja) | 2022-08-10 |
| JP2022535745A5 true JP2022535745A5 (enExample) | 2023-06-08 |
Family
ID=73553945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021570364A Pending JP2022535745A (ja) | 2019-05-31 | 2020-06-01 | 最適化されたフェニルアラニンヒドロキシラーゼ発現 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220162643A1 (enExample) |
| EP (1) | EP3976076A4 (enExample) |
| JP (1) | JP2022535745A (enExample) |
| KR (1) | KR20220068954A (enExample) |
| CN (1) | CN113905768A (enExample) |
| AU (1) | AU2020283069A1 (enExample) |
| BR (1) | BR112021024124A2 (enExample) |
| CA (1) | CA3137698A1 (enExample) |
| IL (1) | IL288400A (enExample) |
| WO (1) | WO2020243717A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010045659A1 (en) | 2008-10-17 | 2010-04-22 | American Gene Technologies International Inc. | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
| US11980663B2 (en) | 2015-07-08 | 2024-05-14 | American Gene Technologies International Inc. | HIV pre-immunization and immunotherapy |
| US10137144B2 (en) | 2016-01-15 | 2018-11-27 | American Gene Technologies International Inc. | Methods and compositions for the activation of gamma-delta T-cells |
| IL297238B2 (en) | 2016-01-15 | 2024-08-01 | American Gene Tech Int Inc | Methods and preparations for gamma-delta T-cell activation |
| JP7153332B2 (ja) | 2016-02-08 | 2022-10-14 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Ｈｉｖワクチン接種および免疫療法 |
| ES2911448T3 (es) | 2016-03-09 | 2022-05-19 | American Gene Tech Int Inc | Vectores combinados y métodos para el tratamiento del cáncer |
| WO2017213697A1 (en) | 2016-06-08 | 2017-12-14 | American Gene Technologies International Inc. | Non-integrating viral delivery system and methods related thereto |
| CA3028982A1 (en) | 2016-07-08 | 2018-01-11 | American Gene Technologies International Inc. | Hiv pre-immunization and immunotherapy |
| WO2018017882A1 (en) | 2016-07-21 | 2018-01-25 | American Gene Technologies International Inc. | Viral vectors for treating parkinson's disease |
| US11820999B2 (en) | 2017-04-03 | 2023-11-21 | American Gene Technologies International Inc. | Compositions and methods for treating phenylketonuria |
| US12559769B2 (en) | 2017-06-16 | 2026-02-24 | American Gene Technologies International Inc. | Methods and compositions for the activation of tumor cytotoxicity via human gamma-delta t-cells |
| US11939601B2 (en) | 2017-11-22 | 2024-03-26 | Modernatx, Inc. | Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria |
| MX2023003019A (es) * | 2020-09-16 | 2023-05-08 | Generation Bio Co | Vectores de adn de extremo cerrado y usos de estos para expresar fenilalanina hidroxilasa (pah). |
| EP4402267A4 (en) * | 2021-09-16 | 2025-11-26 | Generation Bio Co | Liver-specific expression cassettes, vectors, and their uses for expressing therapeutic proteins |
| CN115772503B (zh) * | 2022-08-16 | 2023-10-17 | 广东省南山医药创新研究院 | 一种表达pah的基因修饰细胞药物及其制备方法与应用 |
| IL327036A (en) * | 2023-09-19 | 2026-05-01 | Poseida Therapeutics Inc | Compositions and methods for combining viral vectors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013151664A1 (en) * | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins |
| EP3574923A1 (en) * | 2013-10-22 | 2019-12-04 | Translate Bio, Inc. | Mrna therapy for phenylketonuria |
| CN115094062A (zh) * | 2015-04-16 | 2022-09-23 | 埃默里大学 | 用于肝脏中蛋白质表达的重组启动子和载体及其用途 |
| WO2017106326A1 (en) * | 2015-12-14 | 2017-06-22 | The Trustees Of The University Of Pennsylvania | Aav-anti pcsk9 antibody constructs and uses thereof |
| AU2017248189B2 (en) * | 2016-04-08 | 2021-04-29 | Translate Bio, Inc. | Multimeric coding nucleic acid and uses thereof |
| EP3562494A4 (en) * | 2016-12-30 | 2020-08-19 | The Trustees Of The University Of Pennsylvania | GENE THERAPY FOR THE TREATMENT OF PHENYLKETONURIS |
| US11820999B2 (en) * | 2017-04-03 | 2023-11-21 | American Gene Technologies International Inc. | Compositions and methods for treating phenylketonuria |
| KR20200057766A (ko) * | 2017-10-02 | 2020-05-26 | 아메리칸 진 테크놀로지스 인터내셔널 인코포레이티드 | 페닐케톤뇨증을 치료하기 위한 프로모터 및 인핸서 조합을 포함하는 벡터 |
-
2020
- 2020-06-01 BR BR112021024124A patent/BR112021024124A2/pt unknown
- 2020-06-01 WO PCT/US2020/035584 patent/WO2020243717A1/en not_active Ceased
- 2020-06-01 US US17/610,111 patent/US20220162643A1/en active Pending
- 2020-06-01 CN CN202080040373.5A patent/CN113905768A/zh active Pending
- 2020-06-01 JP JP2021570364A patent/JP2022535745A/ja active Pending
- 2020-06-01 KR KR1020217042390A patent/KR20220068954A/ko active Pending
- 2020-06-01 EP EP20814445.1A patent/EP3976076A4/en active Pending
- 2020-06-01 CA CA3137698A patent/CA3137698A1/en active Pending
- 2020-06-01 AU AU2020283069A patent/AU2020283069A1/en not_active Abandoned
-
2021
- 2021-11-25 IL IL288400A patent/IL288400A/en unknown