JP2020535828A5 - - Google Patents
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- JP2020535828A5 JP2020535828A5 JP2020518812A JP2020518812A JP2020535828A5 JP 2020535828 A5 JP2020535828 A5 JP 2020535828A5 JP 2020518812 A JP2020518812 A JP 2020518812A JP 2020518812 A JP2020518812 A JP 2020518812A JP 2020535828 A5 JP2020535828 A5 JP 2020535828A5
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- JP
- Japan
- Prior art keywords
- viral vector
- seq
- vector according
- cells
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023101880A JP2023115125A (ja) | 2017-10-02 | 2023-06-21 | フェニルケトン尿症を処置するための、プロモーターとエンハンサーの組み合わせを有するベクター |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762566979P | 2017-10-02 | 2017-10-02 | |
| US62/566,979 | 2017-10-02 | ||
| PCT/US2018/053919 WO2019070674A2 (en) | 2017-10-02 | 2018-10-02 | VECTORS COMPRISING PROMOTER AND ACTIVATOR COMBINATIONS FOR THE TREATMENT OF PHENYLCETONURIA |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023101880A Division JP2023115125A (ja) | 2017-10-02 | 2023-06-21 | フェニルケトン尿症を処置するための、プロモーターとエンハンサーの組み合わせを有するベクター |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020535828A JP2020535828A (ja) | 2020-12-10 |
| JP2020535828A5 true JP2020535828A5 (enExample) | 2021-11-04 |
| JP7838779B2 JP7838779B2 (ja) | 2026-04-01 |
Family
ID=65994855
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020518812A Active JP7838779B2 (ja) | 2017-10-02 | 2018-10-02 | フェニルケトン尿症を処置するための、プロモーターとエンハンサーの組み合わせを有するベクター |
| JP2023101880A Pending JP2023115125A (ja) | 2017-10-02 | 2023-06-21 | フェニルケトン尿症を処置するための、プロモーターとエンハンサーの組み合わせを有するベクター |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023101880A Pending JP2023115125A (ja) | 2017-10-02 | 2023-06-21 | フェニルケトン尿症を処置するための、プロモーターとエンハンサーの組み合わせを有するベクター |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200318081A1 (enExample) |
| EP (1) | EP3692157A4 (enExample) |
| JP (2) | JP7838779B2 (enExample) |
| KR (1) | KR20200057766A (enExample) |
| CN (1) | CN111433368A (enExample) |
| AU (1) | AU2018345745A1 (enExample) |
| BR (1) | BR112020006672A2 (enExample) |
| CA (1) | CA3077355A1 (enExample) |
| IL (1) | IL273670B2 (enExample) |
| WO (1) | WO2019070674A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010045659A1 (en) | 2008-10-17 | 2010-04-22 | American Gene Technologies International Inc. | Safe lentiviral vectors for targeted delivery of multiple therapeutic molecules |
| US11980663B2 (en) | 2015-07-08 | 2024-05-14 | American Gene Technologies International Inc. | HIV pre-immunization and immunotherapy |
| IL297238B2 (en) | 2016-01-15 | 2024-08-01 | American Gene Tech Int Inc | Methods and preparations for gamma-delta T-cell activation |
| US10137144B2 (en) | 2016-01-15 | 2018-11-27 | American Gene Technologies International Inc. | Methods and compositions for the activation of gamma-delta T-cells |
| JP7153332B2 (ja) | 2016-02-08 | 2022-10-14 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | Ｈｉｖワクチン接種および免疫療法 |
| ES2911448T3 (es) | 2016-03-09 | 2022-05-19 | American Gene Tech Int Inc | Vectores combinados y métodos para el tratamiento del cáncer |
| WO2017213697A1 (en) | 2016-06-08 | 2017-12-14 | American Gene Technologies International Inc. | Non-integrating viral delivery system and methods related thereto |
| CA3028982A1 (en) | 2016-07-08 | 2018-01-11 | American Gene Technologies International Inc. | Hiv pre-immunization and immunotherapy |
| WO2018017882A1 (en) | 2016-07-21 | 2018-01-25 | American Gene Technologies International Inc. | Viral vectors for treating parkinson's disease |
| US11820999B2 (en) | 2017-04-03 | 2023-11-21 | American Gene Technologies International Inc. | Compositions and methods for treating phenylketonuria |
| US12559769B2 (en) | 2017-06-16 | 2026-02-24 | American Gene Technologies International Inc. | Methods and compositions for the activation of tumor cytotoxicity via human gamma-delta t-cells |
| BR112021024124A2 (pt) * | 2019-05-31 | 2022-01-11 | American Gene Tech Int Inc | Expressão otimizada de fenilalanina hidroxilase |
| WO2021144649A2 (en) * | 2020-01-16 | 2021-07-22 | Takeda Pharmaceutical Company Limited | Adeno associated virus based gene therapy for phenylketonuria |
| TW202208632A (zh) * | 2020-05-27 | 2022-03-01 | 美商同源醫藥公司 | 用於恢復ｐａｈ基因功能的腺相關病毒組成物及其使用方法 |
| KR20230079172A (ko) | 2020-10-01 | 2023-06-05 | 젠자임 코포레이션 | 간-유도 유전자 대체 요법에 의한 pku의 치료를 위한 인간 pah 발현 카세트 |
| WO2023225569A1 (en) * | 2022-05-17 | 2023-11-23 | Umoja Biopharma, Inc. | Manufacturing viral particles |
| CN115772503B (zh) * | 2022-08-16 | 2023-10-17 | 广东省南山医药创新研究院 | 一种表达pah的基因修饰细胞药物及其制备方法与应用 |
| TWI893802B (zh) * | 2023-05-11 | 2025-08-11 | 大陸商四川至善唯新生物科技有限公司 | 工程化的肝臟特異性增強子、核心啟動子及其應用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001036620A2 (en) * | 1999-11-16 | 2001-05-25 | Genzyme Corporation | Vectors and transgenies with regulatory elements for gene delivery to the liver |
| US20030198620A1 (en) * | 2002-04-16 | 2003-10-23 | Keiya Ozawa | Method of treating amino acid metabolic disorders using recombinant adeno-associated virus virions |
| US20050138677A1 (en) * | 2003-09-16 | 2005-06-23 | Pfister Herbert J. | Transgenic animal model for the treatment of skin tumors |
| EP1854455B1 (en) | 2006-05-10 | 2009-10-07 | Biocompatibles UK Limited | Spherical microcapsules comprising GLP-1 peptides, their production and use |
| EP2008656A1 (en) * | 2007-06-28 | 2008-12-31 | Bergen Teknologioverforing AS | Compositions for the treatment of hyperphenylalaninemia |
| SG10201604810UA (en) * | 2012-02-07 | 2016-08-30 | Global Bio Therapeutics Inc | Compartmentalized method of nucleic acid delivery and compositions and uses thereof |
| CN105813579B (zh) | 2013-08-08 | 2019-05-07 | 全球生物疗法有限公司 | 用于微创手术过程的夹具装置和其应用 |
| ES2744565T3 (es) * | 2014-04-25 | 2020-02-25 | Genethon | Tratamiento de la hiperbilirrubinemia |
| WO2017100551A1 (en) * | 2015-12-09 | 2017-06-15 | Alexion Pharmaceuticals, Inc. | HETEROLOGOUS UTR SEQUENCES FOR ENHANCED mRNA EXPRESSION |
| US11820999B2 (en) * | 2017-04-03 | 2023-11-21 | American Gene Technologies International Inc. | Compositions and methods for treating phenylketonuria |
| EP3692141A1 (en) * | 2017-10-03 | 2020-08-12 | Children's Hospital and Clinics of Minnesota | Vectors and methods of use |
| KR20210008501A (ko) * | 2018-05-09 | 2021-01-22 | 바이오마린 파머수티컬 인크. | 페닐케톤뇨증을 치료하는 방법 |
-
2018
- 2018-10-02 KR KR1020207012276A patent/KR20200057766A/ko not_active Ceased
- 2018-10-02 EP EP18864047.8A patent/EP3692157A4/en active Pending
- 2018-10-02 US US16/652,867 patent/US20200318081A1/en active Pending
- 2018-10-02 CN CN201880077904.0A patent/CN111433368A/zh active Pending
- 2018-10-02 BR BR112020006672-9A patent/BR112020006672A2/pt not_active Application Discontinuation
- 2018-10-02 JP JP2020518812A patent/JP7838779B2/ja active Active
- 2018-10-02 IL IL273670A patent/IL273670B2/en unknown
- 2018-10-02 AU AU2018345745A patent/AU2018345745A1/en not_active Abandoned
- 2018-10-02 CA CA3077355A patent/CA3077355A1/en active Pending
- 2018-10-02 WO PCT/US2018/053919 patent/WO2019070674A2/en not_active Ceased
-
2023
- 2023-06-21 JP JP2023101880A patent/JP2023115125A/ja active Pending
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