JP2022535577A5 - - Google Patents

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Publication number
JP2022535577A5
JP2022535577A5 JP2021572409A JP2021572409A JP2022535577A5 JP 2022535577 A5 JP2022535577 A5 JP 2022535577A5 JP 2021572409 A JP2021572409 A JP 2021572409A JP 2021572409 A JP2021572409 A JP 2021572409A JP 2022535577 A5 JP2022535577 A5 JP 2022535577A5
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JP
Japan
Prior art keywords
heterocyclyl
cancer
pharmaceutically acceptable
acceptable salt
alkyl
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JP2021572409A
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English (en)
Japanese (ja)
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JP7541538B2 (ja
JP2022535577A (ja
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Priority claimed from PCT/US2020/035891 external-priority patent/WO2020247475A1/en
Publication of JP2022535577A publication Critical patent/JP2022535577A/ja
Publication of JP2022535577A5 publication Critical patent/JP2022535577A5/ja
Application granted granted Critical
Publication of JP7541538B2 publication Critical patent/JP7541538B2/ja
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JP2021572409A 2019-06-05 2020-06-03 癌を処置するためのprc2阻害剤としてのイミダゾ[1,2-c]ピリミジン誘導体 Active JP7541538B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962857515P 2019-06-05 2019-06-05
US62/857,515 2019-06-05
PCT/US2020/035891 WO2020247475A1 (en) 2019-06-05 2020-06-03 Imidazo[1,2-c]pyrimidine derivatives as prc2 inhibitors for treating cancer

Publications (3)

Publication Number Publication Date
JP2022535577A JP2022535577A (ja) 2022-08-09
JP2022535577A5 true JP2022535577A5 (enExample) 2023-05-08
JP7541538B2 JP7541538B2 (ja) 2024-08-28

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ID=71842807

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JP2021572409A Active JP7541538B2 (ja) 2019-06-05 2020-06-03 癌を処置するためのprc2阻害剤としてのイミダゾ[1,2-c]ピリミジン誘導体

Country Status (9)

Country Link
US (2) US12252493B2 (enExample)
EP (1) EP3980422A1 (enExample)
JP (1) JP7541538B2 (enExample)
KR (1) KR20220027933A (enExample)
CN (1) CN114269748A (enExample)
AU (1) AU2020288563A1 (enExample)
CA (1) CA3142711A1 (enExample)
IL (1) IL288529A (enExample)
WO (1) WO2020247475A1 (enExample)

Families Citing this family (10)

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MX2020007974A (es) 2018-01-31 2020-09-07 Mirati Therapeutics Inc Inhibidores de complejo represivo polycomb 2 (prc2).
US12421228B2 (en) 2019-04-22 2025-09-23 Mirati Therapeutics, Inc. Naphthyridine derivatives as PRC2 inhibitors
EP3980422A1 (en) 2019-06-05 2022-04-13 Mirati Therapeutics, Inc. Imidazo[1,2-c]pyrimidine derivatives as prc2 inhibitors for treating cancer
CN114907385A (zh) * 2021-02-10 2022-08-16 上海青煜医药科技有限公司 氮杂芳基化合物、其制备方法及应用
TW202312995A (zh) * 2021-08-11 2023-04-01 大陸商上海青煜醫藥科技有限公司 氮雜芳基化合物、其製備方法及應用
EP4404932A4 (en) * 2021-09-24 2025-07-23 Oric Pharmaceuticals Inc PRC2 INHIBITORS FOR USE IN THE TREATMENT OF BLOOD DISORDERS
WO2023049723A1 (en) * 2021-09-24 2023-03-30 Oric Pharmaceuticals, Inc. Prc2 inhibitors for use in treating blood disorders
WO2024123669A1 (en) * 2022-12-05 2024-06-13 Oric Pharmaceuticals, Inc. Treatment of prostate cancer having androgen receptor variants
WO2024215699A1 (en) * 2023-04-11 2024-10-17 Oric Pharmaceuticals, Inc. Treatment of t-cell lymphoma
IL326327A (en) * 2023-08-04 2026-04-01 Oric Pharmaceuticals Inc Prostate cancer treatment

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