JP2022532991A5 - - Google Patents
Info
- Publication number
- JP2022532991A5 JP2022532991A5 JP2021563239A JP2021563239A JP2022532991A5 JP 2022532991 A5 JP2022532991 A5 JP 2022532991A5 JP 2021563239 A JP2021563239 A JP 2021563239A JP 2021563239 A JP2021563239 A JP 2021563239A JP 2022532991 A5 JP2022532991 A5 JP 2022532991A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- antigen
- binding fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2019112296A RU2734432C1 (ru) | 2019-04-23 | 2019-04-23 | Моноклональное антитело, которое специфически связывается с GITR |
| RU2019112296 | 2019-04-23 | ||
| PCT/RU2020/050080 WO2020218951A2 (ru) | 2019-04-23 | 2020-04-23 | Моноклональное антитело, которое специфически связывается с gitr |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022532991A JP2022532991A (ja) | 2022-07-21 |
| JP2022532991A5 true JP2022532991A5 (enExample) | 2023-05-02 |
| JP7695200B2 JP7695200B2 (ja) | 2025-06-18 |
Family
ID=69821666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021563239A Active JP7695200B2 (ja) | 2019-04-23 | 2020-04-23 | Ｇｉｔｒに特異的に結合するモノクローナル抗体 |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US12410257B2 (enExample) |
| EP (1) | EP3964525A4 (enExample) |
| JP (1) | JP7695200B2 (enExample) |
| KR (1) | KR20220010501A (enExample) |
| CN (1) | CN110903392B (enExample) |
| AR (1) | AR118763A1 (enExample) |
| AU (1) | AU2020261207A1 (enExample) |
| BR (1) | BR112021021281A2 (enExample) |
| CA (1) | CA3137822A1 (enExample) |
| CL (1) | CL2021002792A1 (enExample) |
| CO (1) | CO2021014153A2 (enExample) |
| EA (1) | EA202192907A1 (enExample) |
| IL (1) | IL287531A (enExample) |
| JO (1) | JOP20210286A1 (enExample) |
| MA (2) | MA54969B2 (enExample) |
| MX (1) | MX2021012962A (enExample) |
| MY (1) | MY210018A (enExample) |
| PE (1) | PE20220144A1 (enExample) |
| PY (1) | PY2018606A (enExample) |
| RU (1) | RU2734432C1 (enExample) |
| TW (1) | TWI803718B (enExample) |
| UY (1) | UY38672A (enExample) |
| WO (1) | WO2020218951A2 (enExample) |
| ZA (1) | ZA202109374B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2724470C1 (ru) * | 2019-11-11 | 2020-06-23 | Автономная некоммерческая образовательная организация высшего образования Сколковский институт науки и технологий | Применение cas9 белка из бактерии pasteurella pneumotropica для модификации геномной днк в клетках |
| CN111732658B (zh) * | 2020-06-28 | 2022-04-26 | 英诺湖医药(杭州)有限公司 | 一组gitr单克隆抗体及其医药用途 |
| CN112540179B (zh) * | 2020-08-06 | 2023-07-07 | 武汉天德生物科技有限公司 | 一种测试ApoE4蛋白含量的ELISA试剂盒 |
| CN112362876B (zh) * | 2020-08-06 | 2023-12-15 | 武汉天德生物科技有限公司 | 一种检测早期老年痴呆症的胶体金试纸条及其制备方法 |
| CN111763257B (zh) * | 2020-09-01 | 2020-12-15 | 北京百奥赛图基因生物技术有限公司 | 抗gitr抗体及其用途 |
| CN114920845A (zh) * | 2020-12-31 | 2022-08-19 | 中元汇吉生物技术股份有限公司 | 特异性结合人IgG4的蛋白及其应用 |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4740461A (en) | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| EP0216846B2 (en) | 1985-04-01 | 1995-04-26 | Celltech Limited | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US4959455A (en) | 1986-07-14 | 1990-09-25 | Genetics Institute, Inc. | Primate hematopoietic growth factors IL-3 and pharmaceutical compositions |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US4912040A (en) | 1986-11-14 | 1990-03-27 | Genetics Institute, Inc. | Eucaryotic expression system |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| ATE158021T1 (de) | 1990-08-29 | 1997-09-15 | Genpharm Int | Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5571894A (en) | 1991-02-05 | 1996-11-05 | Ciba-Geigy Corporation | Recombinant antibodies specific for a growth factor receptor |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| FI941572A7 (fi) | 1991-10-07 | 1994-05-27 | Oncologix Inc | Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä |
| CA2372813A1 (en) | 1992-02-06 | 1993-08-19 | L.L. Houston | Biosynthetic binding protein for cancer marker |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| DE19544393A1 (de) | 1995-11-15 | 1997-05-22 | Hoechst Schering Agrevo Gmbh | Synergistische herbizide Mischungen |
| US6517529B1 (en) | 1999-11-24 | 2003-02-11 | Radius International Limited Partnership | Hemodialysis catheter |
| US7618632B2 (en) * | 2003-05-23 | 2009-11-17 | Wyeth | Method of treating or ameliorating an immune cell associated pathology using GITR ligand antibodies |
| WO2005047327A2 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| US20110123440A1 (en) | 2005-03-29 | 2011-05-26 | Genevieve Hansen | Altered Antibody FC Regions and Uses Thereof |
| AU2006265936A1 (en) | 2005-07-01 | 2007-01-11 | Medimmune, Llc | An integrated approach for generating multidomain protein therapeutics |
| KR101790802B1 (ko) * | 2009-09-03 | 2017-10-27 | 머크 샤프 앤드 돔 코포레이션 | 항-ｇｉｔｒ 항체 |
| TW201605896A (zh) | 2013-08-30 | 2016-02-16 | 安美基股份有限公司 | Gitr抗原結合蛋白 |
| SI3148579T1 (sl) * | 2014-05-28 | 2021-07-30 | Agenus Inc. | Proti GITR antitelesa in postopki z njihovo uporabo |
| PE20170441A1 (es) | 2014-06-06 | 2017-04-26 | Bristol Myers Squibb Co | Anticuerpos contra el receptor del factor de necrosis tumoral inducido por glucocorticoides (gitr) y sus usos |
| WO2016115345A1 (en) * | 2015-01-14 | 2016-07-21 | The Brigham And Women's Hospital, | Treatment of cancer with anti-lap monoclonal antibodies |
| EP3365371B1 (en) | 2015-10-22 | 2025-10-08 | Ablynx NV | Gitr agonists |
| EP3383431A4 (en) | 2015-12-02 | 2019-08-28 | Agenus Inc. | ANTI-GITR ANTIBODIES AND METHOD OF USE THEREOF |
| CN109563170B (zh) | 2016-06-10 | 2023-10-13 | 瑞泽恩制药公司 | 抗gitr抗体及其用途 |
| JP2019519536A (ja) | 2016-07-01 | 2019-07-11 | ファイブ プライム セラピューティクス， インコーポレイテッド | Ｇｉｔｒアゴニストおよびｃｐｇを用いた組み合わせ抗腫瘍療法 |
| WO2018031400A1 (en) * | 2016-08-12 | 2018-02-15 | Janssen Biotech, Inc. | Fc engineered anti-tnfr superfamily member antibodies having enhanced agonistic activity and methods of using them |
| CA3042727A1 (en) * | 2016-11-19 | 2018-05-24 | Potenza Therapeutics, Inc. | Anti-gitr antigen-binding proteins and methods of use thereof |
| EP3576793A4 (en) | 2017-02-06 | 2021-03-31 | Dana Farber Cancer Institute, Inc. | COMPOSITIONS AND PROCEDURES FOR ENHANCING ANTIBODY-MEDIATED RECEPTOR SIGNALING |
| CA3054885A1 (en) * | 2017-03-03 | 2018-09-07 | Rinat Neuroscience Corp. | Anti-gitr antibodies and methods of use thereof |
| TWI788340B (zh) * | 2017-04-07 | 2023-01-01 | 美商必治妥美雅史谷比公司 | 抗icos促效劑抗體及其用途 |
-
2019
- 2019-04-23 RU RU2019112296A patent/RU2734432C1/ru active
- 2019-12-03 TW TW108144110A patent/TWI803718B/zh active
- 2019-12-03 CN CN201911222245.8A patent/CN110903392B/zh active Active
-
2020
- 2020-04-22 UY UY0001038672A patent/UY38672A/es unknown
- 2020-04-23 MA MA54969A patent/MA54969B2/fr unknown
- 2020-04-23 US US17/605,933 patent/US12410257B2/en active Active
- 2020-04-23 AR ARP200101146A patent/AR118763A1/es unknown
- 2020-04-23 AU AU2020261207A patent/AU2020261207A1/en active Pending
- 2020-04-23 KR KR1020217038209A patent/KR20220010501A/ko active Pending
- 2020-04-23 MY MYPI2021006363A patent/MY210018A/en unknown
- 2020-04-23 CA CA3137822A patent/CA3137822A1/en active Pending
- 2020-04-23 EA EA202192907A patent/EA202192907A1/ru unknown
- 2020-04-23 WO PCT/RU2020/050080 patent/WO2020218951A2/ru not_active Ceased
- 2020-04-23 EP EP20794288.9A patent/EP3964525A4/en active Pending
- 2020-04-23 BR BR112021021281A patent/BR112021021281A2/pt unknown
- 2020-04-23 PE PE2021001765A patent/PE20220144A1/es unknown
- 2020-04-23 MX MX2021012962A patent/MX2021012962A/es unknown
- 2020-04-23 JP JP2021563239A patent/JP7695200B2/ja active Active
- 2020-05-06 PY PY202002018606A patent/PY2018606A/es unknown
- 2020-06-30 MA MA55390A patent/MA55390B1/fr unknown
-
2021
- 2021-10-22 CL CL2021002792A patent/CL2021002792A1/es unknown
- 2021-10-22 CO CONC2021/0014153A patent/CO2021014153A2/es unknown
- 2021-10-24 JO JOP/2021/0286A patent/JOP20210286A1/ar unknown
- 2021-10-24 IL IL287531A patent/IL287531A/en unknown
- 2021-11-22 ZA ZA2021/09374A patent/ZA202109374B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107151269B (zh) | 一种pdl-1抗体、其药物组合物及其用途 | |
| JP2022532991A5 (enExample) | ||
| KR20220110177A (ko) | 항인간 클라우딘 18.2 항체 및 그의 적용 | |
| AU2020213579B2 (en) | Anti-PD-1 antibody, antigen-binding fragment thereof and pharmaceutical use thereof | |
| JP2024075737A5 (enExample) | ||
| JP2021524276A5 (enExample) | ||
| JP2019536430A5 (enExample) | ||
| CN114181310A (zh) | 抗tigit抗体、其药物组合物及用途 | |
| CA3114467C (en) | Anti pd-l1 antibody and use thereof | |
| JP2024016024A5 (enExample) | ||
| JP2023518153A5 (enExample) | ||
| EP4506360A1 (en) | Anti-pvrig antibody, pharmaceutical composition thereof and use thereof | |
| WO2023241656A1 (zh) | 包含抗cldn18.2抗体的双特异性抗体、药物组合物及用途 | |
| CN117679505A (zh) | 药物组合及用途 | |
| JP2025514610A5 (enExample) | ||
| JP2024519078A5 (enExample) | ||
| JP2024540062A5 (enExample) | ||
| JP2024508597A5 (enExample) | ||
| CN113549152A (zh) | 一种抗basigin人源化抗体及其应用 | |
| CN106963950B (zh) | 用于治疗肿瘤的联合用药物 | |
| EP4678186A1 (en) | Pharmaceutical composition comprising anti-ctla4-anti-pd-1 bispecific antibody and use thereof | |
| HK40114665A (zh) | 包含抗ctla4-抗pd-1双特异性抗体的药物组合及其用途 | |
| WO2026061538A1 (zh) | 用于治疗恶性肿瘤的抗pd-l1和抗4-1bb双特异性抗体及其药物组合 | |
| RU2021118025A (ru) | Выделенное биспецифическое антитело, которое специфически связывается с CD47 и PD-L1 | |
| CN120623343A (zh) | 一种b7-h6单克隆抗体及其应用 |