JP2022532766A - 家族性腺腫性ポリポーシスを処置するための方法 - Google Patents

家族性腺腫性ポリポーシスを処置するための方法 Download PDF

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JP2022532766A
JP2022532766A JP2021568514A JP2021568514A JP2022532766A JP 2022532766 A JP2022532766 A JP 2022532766A JP 2021568514 A JP2021568514 A JP 2021568514A JP 2021568514 A JP2021568514 A JP 2021568514A JP 2022532766 A JP2022532766 A JP 2022532766A
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eflornithine
sulindac
patient
administered
fap
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JPWO2020236562A5 (https=
JP2022532766A5 (https=
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ユージーン ガーナー
アルフレッド コーエン
ミッシェル ボイティム
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キャンサー プリベンション ファーマシューティカルズ，インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2021568514A 2019-05-17 2020-05-15 家族性腺腫性ポリポーシスを処置するための方法 Pending JP2022532766A (ja)

Applications Claiming Priority (3)

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US201962849590P 2019-05-17 2019-05-17
US62/849,590 2019-05-17
PCT/US2020/033080 WO2020236562A1 (en) 2019-05-17 2020-05-15 Methods for treating familial adenomatous polyposis

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JP2022532766A true JP2022532766A (ja) 2022-07-19
JPWO2020236562A5 JPWO2020236562A5 (https=) 2023-05-16
JP2022532766A5 JP2022532766A5 (https=) 2023-05-16

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US (3) US10945981B2 (https=)
EP (1) EP3968971A1 (https=)
JP (1) JP2022532766A (https=)
CN (1) CN114096240A (https=)
WO (1) WO2020236562A1 (https=)

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JP7262118B2 (ja) * 2016-10-06 2023-04-21 オーバス セラピューティクス インコーポレイテッド 医薬組成物およびその使用
JP2022532766A (ja) * 2019-05-17 2022-07-19 キャンサー プリベンション ファーマシューティカルズ，インコーポレイテッド 家族性腺腫性ポリポーシスを処置するための方法
WO2023283427A2 (en) * 2021-07-09 2023-01-12 Verdure Biotech, Inc. Enteric and delayed release formulations of locally bioavailable drugs (lbd) targeting the colon
WO2026013052A1 (en) * 2024-07-09 2026-01-15 Institut National de la Santé et de la Recherche Médicale Methods of treating familial adenomatous polyposis
US12605349B2 (en) 2024-09-05 2026-04-21 Orbus Therapeutics, Inc. Methods of treating grade 3 astrocytoma

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US20250186380A1 (en) 2025-06-12
US20200360329A1 (en) 2020-11-19
US20220040130A1 (en) 2022-02-10
WO2020236562A1 (en) 2020-11-26
CN114096240A (zh) 2022-02-25
EP3968971A1 (en) 2022-03-23
TW202110431A (zh) 2021-03-16
CA3139162A1 (en) 2020-11-26
US10945981B2 (en) 2021-03-16

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