JP2022529321A5 - - Google Patents
Info
- Publication number
- JP2022529321A5 JP2022529321A5 JP2021559729A JP2021559729A JP2022529321A5 JP 2022529321 A5 JP2022529321 A5 JP 2022529321A5 JP 2021559729 A JP2021559729 A JP 2021559729A JP 2021559729 A JP2021559729 A JP 2021559729A JP 2022529321 A5 JP2022529321 A5 JP 2022529321A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- compound according
- formula
- group
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025060882A JP2025106352A (ja) | 2019-04-22 | 2025-04-02 | 環状リン酸エステル化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962837137P | 2019-04-22 | 2019-04-22 | |
| US62/837,137 | 2019-04-22 | ||
| PCT/US2020/029149 WO2020219464A1 (en) | 2019-04-22 | 2020-04-21 | Cyclic phosphate compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025060882A Division JP2025106352A (ja) | 2019-04-22 | 2025-04-02 | 環状リン酸エステル化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022529321A JP2022529321A (ja) | 2022-06-21 |
| JP2022529321A5 true JP2022529321A5 (https=) | 2023-04-26 |
| JP7661235B2 JP7661235B2 (ja) | 2025-04-14 |
Family
ID=72941350
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559729A Active JP7661235B2 (ja) | 2019-04-22 | 2020-04-21 | 環状リン酸エステル化合物 |
| JP2025060882A Pending JP2025106352A (ja) | 2019-04-22 | 2025-04-02 | 環状リン酸エステル化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025060882A Pending JP2025106352A (ja) | 2019-04-22 | 2025-04-02 | 環状リン酸エステル化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220220145A1 (https=) |
| EP (1) | EP3966221A4 (https=) |
| JP (2) | JP7661235B2 (https=) |
| KR (1) | KR20210154229A (https=) |
| CN (1) | CN113939526A (https=) |
| AU (1) | AU2020263283B2 (https=) |
| CA (1) | CA3136954A1 (https=) |
| MX (1) | MX2021012894A (https=) |
| WO (1) | WO2020219464A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102708995B1 (ko) | 2018-01-10 | 2024-09-23 | 누코리온 파마슈티컬스, 인코포레이티드. | 포스포르(포스포론)아미다타세탈 및 포스프(온)아탈세탈 화합물 |
| US11427550B2 (en) | 2018-01-19 | 2022-08-30 | Nucorion Pharmaceuticals, Inc. | 5-fluorouracil compounds |
| MX2022000573A (es) | 2019-07-17 | 2022-02-10 | Nucorion Pharmaceuticals Inc | Compuestos ciclicos de desoxirribonucleotido. |
| JP2023523415A (ja) * | 2020-04-21 | 2023-06-05 | リガンド・ファーマシューティカルズ・インコーポレイテッド | ヌクレオチドプロドラッグ化合物 |
| WO2021216431A1 (en) * | 2020-04-21 | 2021-10-28 | Ligand Pharmaceuticals, Inc. | Benzyloxy phosph(on)ate compounds |
| EP4232456A4 (en) * | 2020-10-21 | 2026-04-01 | Ligand Pharm Inc | COMPOUNDS OF ANTIVIRAL MEDICINES |
| WO2022245584A1 (en) * | 2021-05-17 | 2022-11-24 | Ligand Pharmaceuticals Incorporated | Unnatural configuration nucleotide prodrug compounds |
| CN118005694B (zh) * | 2023-01-06 | 2025-04-22 | 北京双鹤润创科技有限公司 | 一种环状核苷类似物及其制备方法和应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6023120B2 (ja) * | 1979-08-13 | 1985-06-05 | キッコーマン株式会社 | アデノシン−３′，５′−環状リン酸アルキルトリエステルの製造法 |
| DE3027279A1 (de) * | 1980-07-18 | 1982-05-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Substituierte adenosin-3',5'-phosphorsaeurebenzyltriester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US5834436A (en) * | 1993-04-09 | 1998-11-10 | The Regents Of The University Of California | Membrane-permeant second messengers |
| US5866548A (en) * | 1993-04-09 | 1999-02-02 | The Regents Of The University Of California | Caged membrane-permeant inositol phosphates |
| US5693521A (en) * | 1993-04-09 | 1997-12-02 | The Regents Of The University Of California | Membrane-permeant second messengers |
| WO2007027248A2 (en) * | 2005-05-16 | 2007-03-08 | Valeant Research & Development | 3', 5' - cyclic nucleoside analogues for treatment of hcv |
| US8173621B2 (en) * | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| CA2819041A1 (en) * | 2010-12-22 | 2012-06-28 | Alios Biopharma, Inc. | Cyclic nucleotide analogs |
| US9296778B2 (en) * | 2012-05-22 | 2016-03-29 | Idenix Pharmaceuticals, Inc. | 3′,5′-cyclic phosphate prodrugs for HCV infection |
| EP2906579B1 (en) * | 2012-10-08 | 2018-04-18 | Idenix Pharmaceuticals LLC. | 2'-chloro nucleoside analogs for hcv infection |
| JP2016501200A (ja) * | 2012-11-19 | 2016-01-18 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | ウイルス性疾患を処置するための２−アルキニル置換ヌクレオシド誘導体 |
| BR112015014457A2 (pt) * | 2012-12-21 | 2017-11-21 | Alios Biopharma Inc | composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica e respectivos usos e processos para melhorar ou tratar infecção de hcv, para inibir a atividade da ns5b polimerase do vírus da hepatite c e a replicação de vírus da hepatite c |
| US10202411B2 (en) * | 2014-04-16 | 2019-02-12 | Idenix Pharmaceuticals Llc | 3′-substituted methyl or alkynyl nucleosides nucleotides for the treatment of HCV |
| EP3471737B1 (en) * | 2016-06-20 | 2025-06-04 | Merck Sharp & Dohme LLC | Cyclic phosphate substituted nucleoside compounds and methods of use thereof for the treatment of viral diseases |
| EP3661513A4 (en) | 2017-07-31 | 2021-07-14 | January Therapeutics, Inc. | ORGANOPHOSPHATE DERIVATIVES |
| CN111801339B (zh) | 2018-01-19 | 2025-06-24 | 纽科利制药公司 | 5-氟尿嘧啶化合物 |
| US20210038628A1 (en) * | 2018-03-02 | 2021-02-11 | January Therapeutics, Inc. | Nanoparticle compositions |
-
2020
- 2020-04-21 MX MX2021012894A patent/MX2021012894A/es unknown
- 2020-04-21 AU AU2020263283A patent/AU2020263283B2/en active Active
- 2020-04-21 US US17/604,681 patent/US20220220145A1/en active Pending
- 2020-04-21 CA CA3136954A patent/CA3136954A1/en active Pending
- 2020-04-21 KR KR1020217037884A patent/KR20210154229A/ko not_active Ceased
- 2020-04-21 CN CN202080038544.0A patent/CN113939526A/zh active Pending
- 2020-04-21 JP JP2021559729A patent/JP7661235B2/ja active Active
- 2020-04-21 WO PCT/US2020/029149 patent/WO2020219464A1/en not_active Ceased
- 2020-04-21 EP EP20796308.3A patent/EP3966221A4/en active Pending
-
2025
- 2025-04-02 JP JP2025060882A patent/JP2025106352A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022529321A5 (https=) | ||
| CN109528721B (zh) | 联合治疗 | |
| JP2020169171A5 (https=) | ||
| RU2009102278A (ru) | Модуляторы рецептора s1p для лечения рассеянного склероза | |
| FI3518960T3 (fi) | Annostusohjelma kontrolloidusti vapautuvalle PTH-yhdisteelle | |
| RU97115713A (ru) | Соединения, содержащие бензопиран и способ их применения | |
| CN1129397A (zh) | 治疗眼炎的含3-苯甲酰基苯乙酸衍生物的局部给药组合物 | |
| JP2022137237A5 (https=) | ||
| RU2004106555A (ru) | Производные фенэтаноламина для лечения респираторных заболеваний | |
| JP2002508302A (ja) | 鎮痛薬として有用なα−アミノアミド誘導体 | |
| RU2012110380A (ru) | Новое производное 5-фторурацила | |
| JP2022527556A5 (https=) | ||
| JP2023546565A5 (https=) | ||
| JP2012525437A5 (https=) | ||
| JP2015535847A (ja) | ケタミン誘導体 | |
| RU2005121927A (ru) | Производные безводного кристаллического азидоцитозинполусульфата | |
| RU2002101622A (ru) | Нафтохиноновые производные и их использование для лечения и борьбы с туберкулезом | |
| MX2022011242A (es) | Inmunomodulación de o-het/aril azálidos. | |
| RU2008131907A (ru) | Новые соединения | |
| JP2023522866A5 (https=) | ||
| JP2009507810A (ja) | 自己免疫性疾患の処置 | |
| RU2011129771A (ru) | Противораковые соединения | |
| US4148911A (en) | Method of treating respiratory disorders | |
| RU2004109817A (ru) | Производные аминопиррола в качестве противовоспалительных средств | |
| RU2021129954A (ru) | Циклические фосфатные соединения |