JP2022526497A5 - - Google Patents

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Publication number
JP2022526497A5
JP2022526497A5 JP2021556438A JP2021556438A JP2022526497A5 JP 2022526497 A5 JP2022526497 A5 JP 2022526497A5 JP 2021556438 A JP2021556438 A JP 2021556438A JP 2021556438 A JP2021556438 A JP 2021556438A JP 2022526497 A5 JP2022526497 A5 JP 2022526497A5
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JP
Japan
Prior art keywords
cell line
dhodh
endogenous
gene
sequence
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JP2021556438A
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English (en)
Japanese (ja)
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JP7609795B2 (ja
JP2022526497A (ja
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Priority claimed from PCT/EP2020/057583 external-priority patent/WO2020188021A1/en
Publication of JP2022526497A publication Critical patent/JP2022526497A/ja
Publication of JP2022526497A5 publication Critical patent/JP2022526497A5/ja
Application granted granted Critical
Publication of JP7609795B2 publication Critical patent/JP7609795B2/ja
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JP2021556438A 2019-03-19 2020-03-19 新規選択マーカーを含む細胞株及びタンパク質製造のためのそれらの使用 Active JP7609795B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19305331.1 2019-03-19
EP19305331 2019-03-19
PCT/EP2020/057583 WO2020188021A1 (en) 2019-03-19 2020-03-19 Novel selection marker-comprising cell line and uses thereof for protein production

Publications (3)

Publication Number Publication Date
JP2022526497A JP2022526497A (ja) 2022-05-25
JP2022526497A5 true JP2022526497A5 (https=) 2023-03-06
JP7609795B2 JP7609795B2 (ja) 2025-01-07

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ID=66001151

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021556438A Active JP7609795B2 (ja) 2019-03-19 2020-03-19 新規選択マーカーを含む細胞株及びタンパク質製造のためのそれらの使用

Country Status (14)

Country Link
US (1) US12529071B2 (https=)
EP (1) EP3942054A1 (https=)
JP (1) JP7609795B2 (https=)
KR (1) KR20210141511A (https=)
CN (1) CN113811615B (https=)
AU (1) AU2020242966B2 (https=)
BR (1) BR112021018124A2 (https=)
CA (1) CA3134116A1 (https=)
IL (1) IL286419A (https=)
MX (1) MX2021011303A (https=)
SG (1) SG11202110105UA (https=)
TW (1) TWI881970B (https=)
WO (1) WO2020188021A1 (https=)
ZA (1) ZA202106718B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI912369B (zh) * 2020-09-21 2026-01-21 法商賽諾菲公司 用於生產治療蛋白之高生產重組中國倉鼠卵巢細胞株之世代

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
KR100267720B1 (ko) 1997-12-29 2001-03-02 박호군 사람 글루타민 합성효소 유전자를 포함하는 발현벡터 및 이를 이용하여 동물세포에서 에리트로포이에틴을 고수율로 생산하는 방법
US20030166201A1 (en) * 2001-04-30 2003-09-04 Jensen Michael C. Selection systems for genetically modified cells
AU2007250735A1 (en) * 2006-05-16 2007-11-22 Daiichi Sankyo Company, Limited Method for high-level secretory production of protein
US9234210B2 (en) 2010-08-25 2016-01-12 Intrexon Ceu, Inc. Selectable markers and related methods
RU2556816C1 (ru) 2014-03-12 2015-07-20 Открытое акционерное общество "Фармацевтический импорт, экспорт" (ОАО "Фармимэкс") Штамм клеток яичников китайского хомячка - продуцент рекомбинантного антитела против фактора некроза опухоли альфа человека
AU2015334872B2 (en) 2014-10-23 2021-12-16 Sanofi Novel selection marker for cell transfection and protein production
US11096934B2 (en) 2015-09-01 2021-08-24 The Broad Institute, Inc. Compounds and methods useful for treating or preventing hematological cancers
US10736911B2 (en) * 2015-12-29 2020-08-11 The Board Of Trustees Of The Leland Stanford Junior University Use of a DHODH inhibitor in combination with an inhibitor of pyrimidine salvage
CN109777837A (zh) 2018-12-26 2019-05-21 首都医科大学 一种利用CRISPR/Cas9系统构建致死基因全身性敲除小鼠模型的方法
TWI912369B (zh) 2020-09-21 2026-01-21 法商賽諾菲公司 用於生產治療蛋白之高生產重組中國倉鼠卵巢細胞株之世代

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