JP2022522312A5 - - Google Patents
Info
- Publication number
- JP2022522312A5 JP2022522312A5 JP2021559054A JP2021559054A JP2022522312A5 JP 2022522312 A5 JP2022522312 A5 JP 2022522312A5 JP 2021559054 A JP2021559054 A JP 2021559054A JP 2021559054 A JP2021559054 A JP 2021559054A JP 2022522312 A5 JP2022522312 A5 JP 2022522312A5
- Authority
- JP
- Japan
- Prior art keywords
- unsubstituted
- substituted
- alkyl
- monocyclic
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024101773A JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962828919P | 2019-04-03 | 2019-04-03 | |
| US62/828,919 | 2019-04-03 | ||
| US201962932686P | 2019-11-08 | 2019-11-08 | |
| US62/932,686 | 2019-11-08 | ||
| PCT/US2020/026116 WO2020205934A1 (en) | 2019-04-03 | 2020-04-01 | Pyrrole compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024101773A Division JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022522312A JP2022522312A (ja) | 2022-04-15 |
| JP2022522312A5 true JP2022522312A5 (enExample) | 2023-04-11 |
| JP7627008B2 JP7627008B2 (ja) | 2025-02-05 |
Family
ID=72667046
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021559054A Active JP7627008B2 (ja) | 2019-04-03 | 2020-04-01 | ピロール化合物 |
| JP2024101773A Active JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A Active JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024101773A Active JP7710215B2 (ja) | 2019-04-03 | 2024-06-25 | ピロール化合物 |
| JP2025110439A Active JP7811768B2 (ja) | 2019-04-03 | 2025-06-30 | ピロール化合物 |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US11191747B2 (enExample) |
| EP (2) | EP4733305A2 (enExample) |
| JP (3) | JP7627008B2 (enExample) |
| KR (2) | KR102933784B1 (enExample) |
| CN (4) | CN121108034A (enExample) |
| AU (2) | AU2020253444C1 (enExample) |
| BR (1) | BR112021019817A2 (enExample) |
| CA (1) | CA3134635A1 (enExample) |
| CL (1) | CL2021002575A1 (enExample) |
| CO (1) | CO2021014210A2 (enExample) |
| DK (1) | DK3947349T3 (enExample) |
| FI (1) | FI3947349T3 (enExample) |
| GE (2) | GEAP202515762A (enExample) |
| IL (1) | IL286902B2 (enExample) |
| MA (1) | MA55564A (enExample) |
| MX (1) | MX2021012105A (enExample) |
| PE (1) | PE20220252A1 (enExample) |
| PH (1) | PH12021552513A1 (enExample) |
| PT (1) | PT3947349T (enExample) |
| SG (1) | SG11202110718PA (enExample) |
| TW (1) | TWI846853B (enExample) |
| UA (1) | UA129029C2 (enExample) |
| WO (1) | WO2020205934A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102933784B1 (ko) | 2019-04-03 | 2026-03-06 | 알리고스 테라퓨틱스 인코포레이티드 | 피롤 화합물 |
| WO2022143610A1 (zh) * | 2020-12-29 | 2022-07-07 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的应用 |
| WO2022156758A1 (zh) * | 2021-01-22 | 2022-07-28 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的用途 |
| CN118201942A (zh) | 2021-09-08 | 2024-06-14 | 阿利戈斯治疗公司 | 经修饰的短干扰核酸(siNA)分子和其用途 |
| CN116768776B (zh) * | 2022-03-17 | 2024-07-02 | 成都微芯药业有限公司 | 吡咯酰胺类化合物及其制备方法和用途 |
| CN116120219A (zh) * | 2022-12-27 | 2023-05-16 | 吉斯凯(苏州)制药有限公司 | 一种多取代吡咯类化合物及其制备方法和在制备hbv衣壳蛋白抑制剂中的应用 |
| AU2024212652A1 (en) * | 2023-01-26 | 2025-07-10 | Aligos Therapeutics, Inc. | Hepatitis b combination therapies |
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| US4784782A (en) | 1986-03-27 | 1988-11-15 | The Lubrizol Corporation | Heterocyclic compounds useful as additives for lubricant and fuel compositions |
| WO2002006278A1 (en) | 2000-07-17 | 2002-01-24 | Ranbaxy Laboratories Limited | Oxazolidinone derivatives as antimicrobials |
| WO2002085908A1 (en) | 2001-04-24 | 2002-10-31 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
| US6956040B2 (en) | 2001-07-16 | 2005-10-18 | Ranbaxy Laboratories Limited | Oxazolidinone piperazinyl derivatives as potential antimicrobials |
| GB0119172D0 (en) | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
| NZ541234A (en) | 2002-12-20 | 2008-06-30 | Amgen Inc | Asthma and allergic inflammation modulators |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| GB2398299A (en) | 2003-02-13 | 2004-08-18 | Melacure Therapeutics Ab | Pharmaceutically active phenyl-pyrrole derivatives |
| US20070191336A1 (en) | 2003-12-24 | 2007-08-16 | Flynn Daniel L | Anti-inflammatory medicaments |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| AU2005221959C1 (en) | 2004-03-13 | 2010-06-17 | Kyoto University | Novel indole derivative for alkylating specific base sequence of DNA and alkylating agent and drug each comprising the same |
| US20060105355A1 (en) | 2004-11-18 | 2006-05-18 | Karl Maurer | Electrode array device having an adsorbed porous reaction layer having a linker moiety |
| US20060102471A1 (en) | 2004-11-18 | 2006-05-18 | Karl Maurer | Electrode array device having an adsorbed porous reaction layer |
| WO2006092059A1 (en) | 2005-03-04 | 2006-09-08 | Fan Wu | Design and synthesis of novel antimicrobials |
| US20100234379A1 (en) | 2005-07-28 | 2010-09-16 | Bahr Ben A | Dual modulation of endocannabinoid transport and fatty-acid amide hydrolase for treatment of excitotoxicity |
| US20070065877A1 (en) | 2005-09-19 | 2007-03-22 | Combimatrix Corporation | Microarray having a base cleavable succinate linker |
| WO2008033562A2 (en) | 2006-09-15 | 2008-03-20 | Xcovery, Inc. | Kinase inhibitor compounds |
| CA2688136A1 (en) | 2007-06-08 | 2008-12-11 | Advinus Therapeutics Private Limited | Pyrrole-2-carboxamide derivatives as glucokinase activators, their process and pharmaceutical application |
| CA2690243A1 (en) | 2007-06-18 | 2008-12-24 | Sanofi-Aventis | Pyrrole derivatives as p2y12 antagonists |
| CA2754492A1 (en) | 2009-03-05 | 2010-09-10 | Purdue Research Foundation | Method for early imaging of atherosclerosis |
| EP2408770B1 (en) | 2009-03-20 | 2014-11-05 | University Of Virginia Patent Foundation | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials |
| JP2013508413A (ja) | 2009-10-22 | 2013-03-07 | ヴァンダービルト ユニバーシティー | mGluR4アロステリック増強剤、組成物、および神経機能不全を治療する方法 |
| RU2012154447A (ru) | 2010-05-12 | 2014-06-20 | Вандербилт Юниверсити | Гетероциклические сульфоновые аллостерические потенциаторы mglur4, композиции и способы лечения неврологических дисфункций |
| BR112012032247A2 (pt) | 2010-06-15 | 2015-09-15 | Bayer Ip Gmbh | derivados de ácido antranílico |
| SI2616444T1 (sl) | 2010-09-14 | 2016-03-31 | Instytut Biochemii I Biofizyki Pan | Spojine kot modulatorji mutantnega cftr proteina in njihova uporaba za zdravljenje bolezni, povezanih s cftr proteinsko okvaro |
| WO2012047525A2 (en) | 2010-09-27 | 2012-04-12 | Endocyte, Inc. | Folate conjugates for treating inflammation of the eye |
| WO2012078902A2 (en) | 2010-12-08 | 2012-06-14 | Proteostasis Therapeutics, Inc. | Proteostasis regulators |
| WO2012087976A2 (en) | 2010-12-21 | 2012-06-28 | Intermune, Inc. | Novel inhibitors of hepatitis c virus replication |
| WO2012154880A1 (en) | 2011-05-09 | 2012-11-15 | Proteostasis Therapeutics, Inc. | Proteostasis regulators for treating cystic fibrosis and other protein misfolding diseases |
| US20130072473A1 (en) | 2011-05-09 | 2013-03-21 | Proteostasis Therapeutics, Inc. | Compounds for treating protein folding disorders |
| RS58718B1 (sr) | 2011-05-12 | 2019-06-28 | Proteostasis Therapeutics Inc | Regulatori proteostaze |
| JP5977347B2 (ja) | 2011-07-01 | 2016-08-24 | バルーク エス.ブルームバーグ インスティテュート | Hbv感染に対する抗ウイルス剤としてのスルファモイルベンズアミド誘導体 |
| US8835640B1 (en) | 2011-11-16 | 2014-09-16 | Paresh T. Gandhi | Nicotine derivatives |
| HK1210969A1 (en) | 2012-01-20 | 2016-05-13 | 奥克塞拉有限公司 | Substituted heterocyclic compounds for disease treatment |
| EP3345597A3 (en) | 2012-09-19 | 2018-08-22 | Faller & Williams Technology, LLC | Pkc delta inhibitors for use as therapeutics |
| JO3583B1 (ar) | 2013-05-17 | 2020-07-05 | Janssen Sciences Ireland Uc | مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي |
| NO3024819T3 (enExample) | 2013-07-25 | 2018-07-21 | ||
| MX368158B (es) | 2013-10-23 | 2019-09-20 | Janssen Sciences Ireland Uc | Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
| CN104672221B (zh) | 2013-11-29 | 2018-01-23 | 中国科学院上海有机化学研究所 | 一种氟代苯并杂环‑杂芳环结构的合成方法 |
| WO2015134539A1 (en) | 2014-03-03 | 2015-09-11 | The Regents Of The University Of California | Mcl-1 antagonists |
| DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
| US20160166679A1 (en) | 2014-12-12 | 2016-06-16 | Purdue Research Foundation | Method of treatment using folate conjugates and tyrosine kinase inhibitors |
| KR101726060B1 (ko) | 2015-07-28 | 2017-04-12 | 한양대학교 산학협력단 | 디피롤 유도체와 금속 염을 포함하는 염화수소 가스 검출용 조성물 및 이를 포함하는 염화수소 가스 검출용 색변환 센서 |
| KR101726059B1 (ko) | 2015-07-28 | 2017-04-12 | 한양대학교 산학협력단 | 디피롤 유도체와 암모늄 염을 포함하는 브롬화수소 가스 검출용 조성물 및 이를 포함하는 브롬화수소 가스 검출용 색변환 센서 |
| WO2017081615A1 (en) | 2015-11-09 | 2017-05-18 | Wockhardt Limited | 7-oxo -6-(sulfooxy)- 1,6-diazabicyclo [3.2.1] octane containing compounds and their use in treatment of bacterial infections |
| AU2017231817B2 (en) | 2016-03-09 | 2021-02-25 | Emory University | Elimination of hepatitis B virus with antiviral agents |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CN108250121A (zh) | 2016-12-28 | 2018-07-06 | 上海长森药业有限公司 | 磺酰胺-芳基酰胺类化合物及其治疗乙型肝炎的药物用途 |
| CA3094022A1 (en) | 2018-03-30 | 2019-10-03 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof |
| CA3113109A1 (en) | 2018-10-05 | 2020-04-09 | Emory University | Monomer and multimeric anti-hbv agents |
| US11096931B2 (en) | 2019-02-22 | 2021-08-24 | Janssen Sciences Ireland Unlimited Company | Amide derivatives useful in the treatment of HBV infection or HBV-induced diseases |
| KR102933784B1 (ko) | 2019-04-03 | 2026-03-06 | 알리고스 테라퓨틱스 인코포레이티드 | 피롤 화합물 |
| US11903924B2 (en) | 2019-11-13 | 2024-02-20 | Xi'an Xintong Pharmaceutical Research Co., Ltd. | HBV inhibitor and its use |
| WO2022143610A1 (zh) | 2020-12-29 | 2022-07-07 | 广东东阳光药业有限公司 | 新型酰胺吡咯类化合物及其在药物中的应用 |
-
2020
- 2020-04-01 KR KR1020217035886A patent/KR102933784B1/ko active Active
- 2020-04-01 MX MX2021012105A patent/MX2021012105A/es unknown
- 2020-04-01 WO PCT/US2020/026116 patent/WO2020205934A1/en not_active Ceased
- 2020-04-01 MA MA055564A patent/MA55564A/fr unknown
- 2020-04-01 UA UAA202105907A patent/UA129029C2/uk unknown
- 2020-04-01 CN CN202511330314.2A patent/CN121108034A/zh active Pending
- 2020-04-01 EP EP26163262.4A patent/EP4733305A2/en active Pending
- 2020-04-01 PH PH1/2021/552513A patent/PH12021552513A1/en unknown
- 2020-04-01 CN CN202080028131.4A patent/CN114258391A/zh active Pending
- 2020-04-01 TW TW109111398A patent/TWI846853B/zh active
- 2020-04-01 GE GEAP202515762A patent/GEAP202515762A/en unknown
- 2020-04-01 JP JP2021559054A patent/JP7627008B2/ja active Active
- 2020-04-01 CN CN202511435986.XA patent/CN121108187A/zh active Pending
- 2020-04-01 BR BR112021019817A patent/BR112021019817A2/pt unknown
- 2020-04-01 KR KR1020267006069A patent/KR20260036605A/ko active Pending
- 2020-04-01 US US16/837,515 patent/US11191747B2/en active Active
- 2020-04-01 EP EP20784496.0A patent/EP3947349B1/en active Active
- 2020-04-01 DK DK20784496.0T patent/DK3947349T3/da active
- 2020-04-01 CA CA3134635A patent/CA3134635A1/en active Pending
- 2020-04-01 PT PT207844960T patent/PT3947349T/pt unknown
- 2020-04-01 SG SG11202110718PA patent/SG11202110718PA/en unknown
- 2020-04-01 CN CN202511436317.4A patent/CN121085825A/zh active Pending
- 2020-04-01 PE PE2021001658A patent/PE20220252A1/es unknown
- 2020-04-01 FI FIEP20784496.0T patent/FI3947349T3/fi active
- 2020-04-01 AU AU2020253444A patent/AU2020253444C1/en active Active
- 2020-04-01 GE GEAP202015762A patent/GEP20257772B/en unknown
- 2020-04-01 IL IL286902A patent/IL286902B2/en unknown
-
2021
- 2021-10-01 CL CL2021002575A patent/CL2021002575A1/es unknown
- 2021-10-25 CO CONC2021/0014210A patent/CO2021014210A2/es unknown
- 2021-11-16 US US17/455,178 patent/US11771680B2/en active Active
-
2023
- 2023-08-22 US US18/453,887 patent/US12599582B2/en active Active
-
2024
- 2024-06-25 JP JP2024101773A patent/JP7710215B2/ja active Active
-
2025
- 2025-06-30 JP JP2025110439A patent/JP7811768B2/ja active Active
- 2025-08-13 AU AU2025217289A patent/AU2025217289A1/en active Pending
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