JP2022521877A5 - - Google Patents
Info
- Publication number
- JP2022521877A5 JP2022521877A5 JP2021534224A JP2021534224A JP2022521877A5 JP 2022521877 A5 JP2022521877 A5 JP 2022521877A5 JP 2021534224 A JP2021534224 A JP 2021534224A JP 2021534224 A JP2021534224 A JP 2021534224A JP 2022521877 A5 JP2022521877 A5 JP 2022521877A5
- Authority
- JP
- Japan
- Prior art keywords
- double
- nucleic acid
- stranded nucleic
- acid inhibitor
- inhibitor molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024070175A JP7748500B2 (ja) | 2018-12-12 | 2024-04-24 | トリループを含む二本鎖核酸インヒビター分子 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862778759P | 2018-12-12 | 2018-12-12 | |
| US62/778,759 | 2018-12-12 | ||
| PCT/US2019/061241 WO2020123083A1 (en) | 2018-12-12 | 2019-11-13 | Double-stranded nucleic acid inhibitor molecules containing a triloop |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024070175A Division JP7748500B2 (ja) | 2018-12-12 | 2024-04-24 | トリループを含む二本鎖核酸インヒビター分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022521877A JP2022521877A (ja) | 2022-04-13 |
| JP2022521877A5 true JP2022521877A5 (enExample) | 2022-11-24 |
| JP7535047B2 JP7535047B2 (ja) | 2024-08-15 |
Family
ID=71076672
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534224A Active JP7535047B2 (ja) | 2018-12-12 | 2019-11-13 | トリループを含む二本鎖核酸インヒビター分子 |
| JP2024070175A Active JP7748500B2 (ja) | 2018-12-12 | 2024-04-24 | トリループを含む二本鎖核酸インヒビター分子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024070175A Active JP7748500B2 (ja) | 2018-12-12 | 2024-04-24 | トリループを含む二本鎖核酸インヒビター分子 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20220064640A1 (enExample) |
| EP (1) | EP3894560A4 (enExample) |
| JP (2) | JP7535047B2 (enExample) |
| KR (1) | KR20210127917A (enExample) |
| CN (1) | CN113454221A (enExample) |
| AU (1) | AU2019397247A1 (enExample) |
| BR (1) | BR112021011294A2 (enExample) |
| CA (1) | CA3122930A1 (enExample) |
| CL (1) | CL2021001552A1 (enExample) |
| IL (1) | IL283775A (enExample) |
| MX (1) | MX2021007001A (enExample) |
| SG (1) | SG11202106046XA (enExample) |
| WO (1) | WO2020123083A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020123083A1 (en) * | 2018-12-12 | 2020-06-18 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules containing a triloop |
| AU2020268798A1 (en) * | 2019-05-03 | 2021-11-04 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules with shortened sense strands |
| CA3190481A1 (en) * | 2020-08-04 | 2022-02-10 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting plp1 expression |
| AU2022315530A1 (en) | 2021-07-20 | 2024-01-18 | Ags Therapeutics Sas | Extracellular vesicles from microalgae, their preparation, and uses |
| WO2023144127A1 (en) | 2022-01-31 | 2023-08-03 | Ags Therapeutics Sas | Extracellular vesicles from microalgae, their biodistribution upon administration, and uses |
| US20230374522A1 (en) * | 2022-04-15 | 2023-11-23 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for modulating scap activity |
| WO2023232976A1 (en) | 2022-06-03 | 2023-12-07 | Ags Therapeutics Sas | Extracellular vesicles from genetically-modified microalgae containing endogenously-loaded cargo, their preparation, and uses |
| WO2024088808A1 (en) | 2022-10-24 | 2024-05-02 | Ags Therapeutics Sas | Extracellular vesicles from microalgae, their biodistribution upon intranasal administration, and uses thereof |
| WO2025176843A1 (en) | 2024-02-21 | 2025-08-28 | Ags Therapeutics Sas | Microalgae extracellular vesicle based gene therapy vectors (mev-gtvs), their preparation, and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1891216B1 (en) * | 2005-05-25 | 2012-02-22 | The University Of York | Hybrid interfering rna |
| DK2341943T3 (en) * | 2008-09-22 | 2019-02-25 | Dicerna Pharmaceuticals Inc | COMPOSITIONS AND METHODS OF SPECIFIC INHIBITION OF DSRNA REPRINT WITH MODIFICATIONS |
| CN102264898B (zh) * | 2008-10-23 | 2013-10-16 | 国立大学法人东京大学 | 微小rna的功能抑制方法 |
| EP2562257A4 (en) * | 2010-04-19 | 2014-10-01 | Riken | PROCESS FOR STABILIZING FUNCTIONAL NUCLEIC ACIDS |
| JP6091424B2 (ja) * | 2011-11-16 | 2017-03-08 | 公立大学法人大阪市立大学 | ＲＮＡｉ分子の活性を抑制するための核酸分子 |
| DK3569711T3 (da) * | 2014-12-15 | 2021-02-22 | Dicerna Pharmaceuticals Inc | Ligandmodificerede dobbeltstrengede nukleinsyrer |
| US10821112B2 (en) * | 2016-03-16 | 2020-11-03 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
| HUE059718T2 (hu) * | 2016-09-02 | 2022-12-28 | Dicerna Pharmaceuticals Inc | 4'-foszfát analógok és azokat tartalmazó oligonukleotidok |
| IL271680B (en) * | 2017-06-29 | 2022-09-01 | Dicerna Pharmaceuticals Inc | Compositions and methods for inhibiting hmgb1 expression |
| JP2021520355A (ja) * | 2018-04-13 | 2021-08-19 | ディセルナ ファーマシューティカルズ インコーポレイテッド | Ｔｍ上昇ヌクレオチドで修飾された二本鎖核酸阻害剤分子 |
| WO2020123083A1 (en) * | 2018-12-12 | 2020-06-18 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules containing a triloop |
-
2019
- 2019-11-13 WO PCT/US2019/061241 patent/WO2020123083A1/en not_active Ceased
- 2019-11-13 JP JP2021534224A patent/JP7535047B2/ja active Active
- 2019-11-13 AU AU2019397247A patent/AU2019397247A1/en not_active Abandoned
- 2019-11-13 CN CN201980091916.3A patent/CN113454221A/zh not_active Withdrawn
- 2019-11-13 SG SG11202106046XA patent/SG11202106046XA/en unknown
- 2019-11-13 KR KR1020217021547A patent/KR20210127917A/ko not_active Ceased
- 2019-11-13 CA CA3122930A patent/CA3122930A1/en active Pending
- 2019-11-13 US US17/311,949 patent/US20220064640A1/en not_active Abandoned
- 2019-11-13 MX MX2021007001A patent/MX2021007001A/es unknown
- 2019-11-13 BR BR112021011294-4A patent/BR112021011294A2/pt not_active IP Right Cessation
- 2019-11-13 EP EP19895099.0A patent/EP3894560A4/en active Pending
-
2021
- 2021-06-07 IL IL283775A patent/IL283775A/en unknown
- 2021-06-11 CL CL2021001552A patent/CL2021001552A1/es unknown
-
2024
- 2024-04-24 JP JP2024070175A patent/JP7748500B2/ja active Active