JP2024536146A5 - - Google Patents

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Publication number
JP2024536146A5
JP2024536146A5 JP2024519313A JP2024519313A JP2024536146A5 JP 2024536146 A5 JP2024536146 A5 JP 2024536146A5 JP 2024519313 A JP2024519313 A JP 2024519313A JP 2024519313 A JP2024519313 A JP 2024519313A JP 2024536146 A5 JP2024536146 A5 JP 2024536146A5
Authority
JP
Japan
Prior art keywords
modified oligonucleotide
compound according
modified
nucleic acid
nucleoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024519313A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024536146A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/077389 external-priority patent/WO2023056446A1/en
Publication of JP2024536146A publication Critical patent/JP2024536146A/ja
Publication of JP2024536146A5 publication Critical patent/JP2024536146A5/ja
Pending legal-status Critical Current

Links

JP2024519313A 2021-10-01 2022-09-30 アンジオテンシノーゲンを調節する組成物及びその使用方法 Pending JP2024536146A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163251562P 2021-10-01 2021-10-01
US63/251,562 2021-10-01
US202163287960P 2021-12-09 2021-12-09
US63/287,960 2021-12-09
PCT/US2022/077389 WO2023056446A1 (en) 2021-10-01 2022-09-30 Angiotensinogen-modulating compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024536146A JP2024536146A (ja) 2024-10-04
JP2024536146A5 true JP2024536146A5 (enExample) 2025-10-07

Family

ID=85783681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519313A Pending JP2024536146A (ja) 2021-10-01 2022-09-30 アンジオテンシノーゲンを調節する組成物及びその使用方法

Country Status (7)

Country Link
US (1) US20240401045A1 (enExample)
EP (1) EP4408525A4 (enExample)
JP (1) JP2024536146A (enExample)
KR (1) KR20240099244A (enExample)
AU (1) AU2022355198A1 (enExample)
CA (1) CA3233330A1 (enExample)
WO (1) WO2023056446A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL312811A (en) 2021-11-16 2024-07-01 Shanghai Argo Biopharmaceutical Co Ltd Composition and method for inhibiting angiotensinogen (agt) protein expression
AU2022396536A1 (en) * 2021-11-24 2024-06-06 Adarx Pharmaceuticals, Inc. Complement factor b-modulating compositions and methods of use thereof
AU2024301682A1 (en) * 2023-07-21 2026-01-22 Adarx Pharmaceuticals, Inc. Coagulation factor xi-modulating compositions and methods of use thereof
WO2025087237A1 (zh) * 2023-10-23 2025-05-01 广东东阳光药业股份有限公司 一种新型的双链siRNA、其缀合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015264038B2 (en) * 2014-05-22 2021-02-11 Alnylam Pharmaceuticals, Inc. Angiotensinogen (AGT) iRNA compositions and methods of use thereof
CN113817735A (zh) * 2015-10-08 2021-12-21 Ionis制药公司 用于调节血管紧张素原表达的化合物和方法
TWI851574B (zh) * 2018-05-14 2024-08-11 美商阿尼拉製藥公司 血管收縮素原(AGT)iRNA組成物及其使用方法
JP2024513972A (ja) * 2021-04-13 2024-03-27 エーダーエックス ファーマシューティカルズ, インコーポレイテッド Rnaサイレンシング剤および使用方法
US20240041913A1 (en) * 2022-04-01 2024-02-08 Adarx Pharmaceuticals, Inc. Angiotensinogen-modulating compositions and methods of use thereof

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