JP2024540101A5 - - Google Patents

Info

Publication number
JP2024540101A5
JP2024540101A5 JP2024525401A JP2024525401A JP2024540101A5 JP 2024540101 A5 JP2024540101 A5 JP 2024540101A5 JP 2024525401 A JP2024525401 A JP 2024525401A JP 2024525401 A JP2024525401 A JP 2024525401A JP 2024540101 A5 JP2024540101 A5 JP 2024540101A5
Authority
JP
Japan
Prior art keywords
lipid
compound according
lipid nanoparticles
compound
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525401A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540101A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/080576 external-priority patent/WO2023078946A1/en
Publication of JP2024540101A publication Critical patent/JP2024540101A/ja
Publication of JP2024540101A5 publication Critical patent/JP2024540101A5/ja
Pending legal-status Critical Current

Links

JP2024525401A 2021-11-02 2022-11-02 オリゴヌクレオチド送達のための脂質ナノ粒子 Pending JP2024540101A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21205899.4 2021-11-02
EP21205899 2021-11-02
PCT/EP2022/080576 WO2023078946A1 (en) 2021-11-02 2022-11-02 Lipid nanoparticles for oligonucleotide delivery

Publications (2)

Publication Number Publication Date
JP2024540101A JP2024540101A (ja) 2024-10-31
JP2024540101A5 true JP2024540101A5 (enExample) 2025-10-31

Family

ID=78500458

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525401A Pending JP2024540101A (ja) 2021-11-02 2022-11-02 オリゴヌクレオチド送達のための脂質ナノ粒子

Country Status (16)

Country Link
US (1) US20250073177A1 (enExample)
EP (2) EP4613740A3 (enExample)
JP (1) JP2024540101A (enExample)
KR (1) KR20240099375A (enExample)
CN (1) CN118215472A (enExample)
AU (1) AU2022381685A1 (enExample)
CA (1) CA3236638A1 (enExample)
DK (1) DK4426269T3 (enExample)
ES (1) ES3048411T3 (enExample)
FI (1) FI4426269T3 (enExample)
IL (1) IL312431B2 (enExample)
MX (1) MX2024005110A (enExample)
PL (1) PL4426269T3 (enExample)
PT (1) PT4426269T (enExample)
WO (1) WO2023078946A1 (enExample)
ZA (1) ZA202403337B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118125994A (zh) * 2022-11-25 2024-06-04 艾斯拓康医药科技(北京)有限公司 可离子化脂质及其应用
WO2025088152A1 (en) 2023-10-27 2025-05-01 Ziphius Nv MODIFIED 5'UTRs
US12599560B2 (en) 2023-11-02 2026-04-14 Longuide Biopharma Corporation Lipids and lipid nanoparticle formulations
CN117550985B (zh) * 2023-11-08 2025-02-18 深圳厚存纳米药业有限公司 一种脂质化合物及其用途
WO2025104023A1 (en) 2023-11-13 2025-05-22 Ziphius Nv MODIFIED ALPHAVIRAL nsP3
WO2025140594A1 (zh) * 2023-12-29 2025-07-03 厦门赛诺邦格生物科技股份有限公司 一种含有多级叔胺的不对称阳离子脂质
WO2026046237A1 (zh) * 2024-08-27 2026-03-05 北京剂泰生命科技有限公司 肺靶向的脂质化合物
CN120943786A (zh) * 2025-07-17 2025-11-14 深圳市艾迪贝克生物技术有限公司 脂质化合物、其纳米颗粒及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451592B1 (en) 1996-04-05 2002-09-17 Chiron Corporation Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
CN1989250B (zh) 2004-05-18 2013-11-20 阿尔法瓦克斯公司 Tc-83衍生的甲病毒属载体、颗粒和方法
US7332322B2 (en) 2004-09-14 2008-02-19 Ilya Frolov Venezuelan equine encephalitis virus replicons with adaptive mutations in the genome and uses thereof
US8691750B2 (en) * 2011-05-17 2014-04-08 Axolabs Gmbh Lipids and compositions for intracellular delivery of biologically active compounds
WO2014028487A1 (en) * 2012-08-13 2014-02-20 Massachusetts Institute Of Technology Amine-containing lipidoids and uses thereof
WO2018232120A1 (en) * 2017-06-14 2018-12-20 Modernatx, Inc. Compounds and compositions for intracellular delivery of agents

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