JP2022521486A5 - - Google Patents
Info
- Publication number
- JP2022521486A5 JP2022521486A5 JP2021547309A JP2021547309A JP2022521486A5 JP 2022521486 A5 JP2022521486 A5 JP 2022521486A5 JP 2021547309 A JP2021547309 A JP 2021547309A JP 2021547309 A JP2021547309 A JP 2021547309A JP 2022521486 A5 JP2022521486 A5 JP 2022521486A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence number
- sequence
- transposase
- cells
- pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962803142P | 2019-02-08 | 2019-02-08 | |
| US62/803,142 | 2019-02-08 | ||
| PCT/US2020/017283 WO2020163755A1 (en) | 2019-02-08 | 2020-02-07 | Transposon-based modifications of immune cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022521486A JP2022521486A (ja) | 2022-04-08 |
| JP2022521486A5 true JP2022521486A5 (enExample) | 2023-02-14 |
Family
ID=71947504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021547309A Pending JP2022521486A (ja) | 2019-02-08 | 2020-02-07 | トランスポゾンに基づく免疫細胞の改変 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220170044A1 (enExample) |
| EP (1) | EP3920941A4 (enExample) |
| JP (1) | JP2022521486A (enExample) |
| KR (1) | KR20220030205A (enExample) |
| CN (1) | CN114502731A (enExample) |
| AU (1) | AU2020218546A1 (enExample) |
| CA (1) | CA3129263A1 (enExample) |
| IL (1) | IL285422A (enExample) |
| SG (1) | SG11202108665PA (enExample) |
| WO (1) | WO2020163755A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210137085A (ko) | 2019-03-05 | 2021-11-17 | 엔카르타, 인크. | Cd19 유도된 키메라 항원 수용체 및 면역 요법에서 이의 용도 |
| US20220370495A1 (en) * | 2019-08-21 | 2022-11-24 | Board Of Regents, The University Of Texas System | Immune cells for adoptive cell therapies |
| CN114651068B (zh) * | 2019-09-16 | 2024-09-13 | 麦克马斯特大学 | 嵌合共刺激受体及其方法和用途 |
| EP4146798A4 (en) | 2020-05-04 | 2025-02-12 | Saliogen Therapeutics, Inc. | TRANSPOSITION-BASED THERAPIES |
| JP2023544161A (ja) * | 2020-10-02 | 2023-10-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | がんの改善されたｔ細胞免疫療法のためのｄｎａ構築物 |
| WO2022087238A1 (en) * | 2020-10-21 | 2022-04-28 | Wisconsin Alumni Research Foundation | Anti-apoptotic vector and method of using the same |
| CN115894706A (zh) * | 2021-09-30 | 2023-04-04 | 北京康辰药业股份有限公司 | 靶向PD-L1和FasL的融合蛋白、核苷酸序列及其应用 |
| WO2023081815A1 (en) * | 2021-11-04 | 2023-05-11 | Saliogen Therapeutics, Inc. | Manufacturing of stem cells |
| AU2022381757A1 (en) * | 2021-11-04 | 2024-05-09 | Saliogen Therapeutics, Inc. | Immune cells with chimeric antigen receptors or chimeric autoantibody receptors |
| JP2024541501A (ja) * | 2021-11-25 | 2024-11-08 | ドイチェス クレブスフォルシュンクスツェントルム スチフトゥング デス エッフェントリヒェン レヒツ | Ｃｄ９５ポリペプチド |
| EP4476246A4 (en) * | 2022-02-07 | 2026-05-13 | Seattle Childrens Hospital D/B/A Seattle Childrens Res Institute | Recombinant proteins that stimulate an immune response in the presence of a naturally inhibitory ligand bond |
| CN119486759A (zh) * | 2022-02-14 | 2025-02-18 | 加利福尼亚大学董事会 | 用于改善t细胞免疫疗法的dna构建体 |
| US20250195572A1 (en) * | 2022-03-15 | 2025-06-19 | New York Genome Center, Inc. | Methods and compositions comprising fusion proteins for improved immunotherapies |
| WO2023178358A2 (en) * | 2022-03-18 | 2023-09-21 | Dna Twopointo, Inc. | Modification of t cells |
| WO2024233669A2 (en) * | 2023-05-11 | 2024-11-14 | Saliogen Therapeutics, Inc. | Compositions and methods for treatment of cystic fibrosis |
| WO2025235576A1 (en) * | 2024-05-08 | 2025-11-13 | Saliogen Therapeutics, Inc. | Myotis lucifugus transposase engineering |
| CN121065098B (zh) * | 2025-11-10 | 2026-04-17 | 浙江大学 | 一种stat3突变的细胞产品及其用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0826043B1 (en) * | 1995-05-04 | 2003-07-02 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE NAVY | Methods for modulating t cell survival by modulating bcl-xl protein level |
| US6143291A (en) * | 1995-05-04 | 2000-11-07 | Us Navy | Methods for modulating T cell survival by modulating bcl-XL protein level |
| FR2736931B1 (fr) * | 1995-07-17 | 1997-09-19 | Univ Paris Curie | Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures |
| WO2003089618A2 (en) * | 2002-04-22 | 2003-10-30 | Regents Of The University Of Minnesota | Transposon system and methods of use |
| WO2010085699A2 (en) * | 2009-01-23 | 2010-07-29 | The Johns Hopkins University | Mammalian piggybac transposon and methods of use |
| US8592211B2 (en) * | 2009-03-20 | 2013-11-26 | The Rockefeller University | Enhanced PiggyBac transposon and methods for transposon mutagenesis |
| RU2729401C2 (ru) * | 2012-10-02 | 2020-08-06 | Мемориал Слоан-Кеттеринг Кэнсер Сентер | Композиции и способы для иммунотерапии |
| US10927384B2 (en) * | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| CA2964785A1 (en) * | 2014-11-05 | 2016-05-12 | Board Of Regents, The University Of Texas System | Gene modified immune effector cells and engineered cells for expansion of immune effector cells |
| LT3359671T (lt) * | 2015-10-08 | 2021-12-10 | Dna Twopointo Inc. | Dnr vektoriai, transpozonai ir transpozazės, skirti eukariotinio genomo modifikacijai |
| EP4289944A3 (en) * | 2015-10-08 | 2024-03-13 | National University Corporation Tokai National Higher Education and Research System | Method for preparing genetically-modified t cells which express chimeric antigen receptor |
| WO2017133175A1 (en) * | 2016-02-04 | 2017-08-10 | Nanjing Legend Biotech Co., Ltd. | Engineered mammalian cells for cancer therapy |
| JP2019506177A (ja) * | 2016-02-26 | 2019-03-07 | ポセイダ セラピューティクス， インコーポレイテッド | トランスポゾン系および使用方法 |
| US11535662B2 (en) * | 2017-01-26 | 2022-12-27 | Novartis Ag | CD28 compositions and methods for chimeric antigen receptor therapy |
| EP4119552A1 (en) * | 2017-02-08 | 2023-01-18 | Dana-Farber Cancer Institute, Inc. | Regulating chimeric antigen receptors |
| US11725210B2 (en) * | 2017-03-17 | 2023-08-15 | Fred Hutchinson Cancer Center | Immunomodulatory fusion proteins and uses thereof |
-
2020
- 2020-02-07 CA CA3129263A patent/CA3129263A1/en active Pending
- 2020-02-07 EP EP20752984.3A patent/EP3920941A4/en not_active Withdrawn
- 2020-02-07 AU AU2020218546A patent/AU2020218546A1/en not_active Abandoned
- 2020-02-07 US US17/429,342 patent/US20220170044A1/en not_active Abandoned
- 2020-02-07 WO PCT/US2020/017283 patent/WO2020163755A1/en not_active Ceased
- 2020-02-07 SG SG11202108665PA patent/SG11202108665PA/en unknown
- 2020-02-07 KR KR1020217028177A patent/KR20220030205A/ko not_active Abandoned
- 2020-02-07 CN CN202080027488.0A patent/CN114502731A/zh active Pending
- 2020-02-07 JP JP2021547309A patent/JP2022521486A/ja active Pending
-
2021
- 2021-08-05 IL IL285422A patent/IL285422A/en unknown
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