JP2022519935A5 - - Google Patents

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Publication number
JP2022519935A5
JP2022519935A5 JP2021557909A JP2021557909A JP2022519935A5 JP 2022519935 A5 JP2022519935 A5 JP 2022519935A5 JP 2021557909 A JP2021557909 A JP 2021557909A JP 2021557909 A JP2021557909 A JP 2021557909A JP 2022519935 A5 JP2022519935 A5 JP 2022519935A5
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JP
Japan
Prior art keywords
cells
cytokine
manipulated
population
car
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021557909A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022519935A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/024671 external-priority patent/WO2020205359A1/en
Publication of JP2022519935A publication Critical patent/JP2022519935A/ja
Publication of JP2022519935A5 publication Critical patent/JP2022519935A5/ja
Pending legal-status Critical Current

Links

JP2021557909A 2019-03-29 2020-03-25 Car-nk細胞の作製方法およびその使用方法 Pending JP2022519935A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962826856P 2019-03-29 2019-03-29
US62/826,856 2019-03-29
PCT/US2020/024671 WO2020205359A1 (en) 2019-03-29 2020-03-25 Methods for production of car-nk cells and use thereof

Publications (2)

Publication Number Publication Date
JP2022519935A JP2022519935A (ja) 2022-03-25
JP2022519935A5 true JP2022519935A5 (enExample) 2023-04-03

Family

ID=72667448

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021557909A Pending JP2022519935A (ja) 2019-03-29 2020-03-25 Car-nk細胞の作製方法およびその使用方法

Country Status (13)

Country Link
US (1) US20220325245A1 (enExample)
EP (1) EP3947647A4 (enExample)
JP (1) JP2022519935A (enExample)
KR (1) KR20220004992A (enExample)
CN (1) CN113811604A (enExample)
AR (1) AR118510A1 (enExample)
AU (1) AU2020254420A1 (enExample)
BR (1) BR112021019411A2 (enExample)
CA (1) CA3135407A1 (enExample)
CO (1) CO2021012719A2 (enExample)
MX (1) MX2021011816A (enExample)
TW (1) TW202104252A (enExample)
WO (1) WO2020205359A1 (enExample)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
KR101520534B1 (ko) 2012-05-07 2015-05-21 고려대학교 산학협력단 말초혈액단핵구 유래 자연 살해세포의 유도 및 증식 방법
CN115710576A (zh) 2018-02-01 2023-02-24 Nkmax有限公司 产生天然杀伤细胞的方法和用于治疗癌症的组合物
WO2019165121A1 (en) 2018-02-21 2019-08-29 Board Of Regents, The University Of Texas System Methods for activation and expansion of natural killer cells and uses therof
SG11202010763VA (en) * 2018-05-03 2020-11-27 Univ Texas Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
JP7773789B2 (ja) 2020-03-28 2025-11-20 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 癌の治療のための細胞免疫療法
GB202005216D0 (en) * 2020-04-08 2020-05-20 Autolus Ltd Cell
AU2022218710A1 (en) * 2021-02-09 2023-08-10 Takeda Pharmaceutical Company Limited Methods and compositions for freezing and thawing mammalian cells
IL310307A (en) * 2021-07-23 2024-03-01 Univ Texas Cd3-expressing natural killer cells with enhanced function for adoptive immunotherapy
CN116262793A (zh) * 2021-12-13 2023-06-16 上海恒润达生生物科技股份有限公司 膜整合型融合蛋白、含有其的细胞及用途
WO2023164455A2 (en) * 2022-02-23 2023-08-31 Aloe Therapeutics Inc Compositions and methods to modulate the immune system
CN115896016B (zh) * 2022-09-07 2023-09-12 普华赛尔生物医疗科技有限公司 培养组合物及其在培养免疫细胞中的应用
WO2024058589A1 (ko) * 2022-09-16 2024-03-21 한국과학기술연구원 유전자 가위 넉-인을 이용하여 제조한 키메릭 항원 수용체 세포 및 이의 용도
EP4602152A1 (en) * 2022-10-10 2025-08-20 Kite Pharma, Inc. New large scale car-t immune cell manufacturing method utilizing lentiviral vector transfection
CN116168765B (zh) * 2023-04-25 2023-08-18 山东大学 基于改进strobemer的基因序列生成方法及系统
EP4719352A1 (en) 2023-05-31 2026-04-08 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2025006799A1 (en) * 2023-06-27 2025-01-02 Capstan Therapeutics, Inc. Extracorporeal and ex vivo engineering of select cell populations from peripheral blood
CN116769722B (zh) * 2023-07-04 2024-07-16 杭州荣谷生物科技有限公司 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用
EP4784165A1 (en) * 2023-09-25 2026-08-05 Legend Biotech USA Inc. Modified immune cells and calcineurin inhibitors and uses thereof
WO2025169136A1 (en) * 2024-02-09 2025-08-14 Takeda Pharmaceutical Company Limited Dosing regimen for cd19 car nk cells in treating cancer
US12655391B2 (en) * 2024-02-28 2026-06-16 Gene Solutions Joint Stock Company Modified K562 feeder cell line expressing factors that enhance the activation and proliferation of natural killer cells and a method for its production

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015339447B2 (en) * 2014-10-27 2021-08-12 University Of Central Florida Research Foundation, Inc. Methods and compositions for natural killer cells
EP3138905A1 (en) * 2015-09-04 2017-03-08 Miltenyi Biotec GmbH Method for natural killer cell expansion
CN107868791B (zh) * 2016-09-26 2021-11-23 阿思科力(苏州)生物科技有限公司 一种加强型Slit2 CAR-T和CAR-NK细胞制备方法和应用
JP2020517259A (ja) * 2017-04-19 2020-06-18 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム 操作された抗原受容体を発現する免疫細胞
SG11202008008UA (en) * 2018-02-21 2020-09-29 Univ Texas Universal antigen presenting cells and uses thereof
SG11202010763VA (en) * 2018-05-03 2020-11-27 Univ Texas Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
EP3790958A1 (en) * 2018-05-08 2021-03-17 Life Technologies Corporation Compositions and methods for culturing and expanding cells

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