TW202104252A - 用於生產car-nk細胞之方法及其用途 - Google Patents
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| IL276365B2 (en) | 2018-02-01 | 2023-10-01 | Nkmax Co Ltd | A method for the production of natural killer cells and a preparation for cancer treatment |
| US12473336B2 (en) | 2018-02-21 | 2025-11-18 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses thereof |
| KR20210005240A (ko) * | 2018-05-03 | 2021-01-13 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 면역 관문 차단과 함께 키메라 항원 수용체를 발현하도록 가공된 천연 킬러 세포 |
| GB202005216D0 (en) * | 2020-04-08 | 2020-05-20 | Autolus Ltd | Cell |
| US20240325443A1 (en) * | 2021-07-23 | 2024-10-03 | Board Of Regents, The University Of Texas System | Cd3-expressing natural killer cells with enhanced function for adoptive immunotherapy |
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| CA3244259A1 (en) * | 2022-02-23 | 2023-08-31 | Aloe Therapeutics Inc | Compositions and methods for modulating the immune system |
| CN115896016B (zh) * | 2022-09-07 | 2023-09-12 | 普华赛尔生物医疗科技有限公司 | 培养组合物及其在培养免疫细胞中的应用 |
| WO2024058589A1 (ko) * | 2022-09-16 | 2024-03-21 | 한국과학기술연구원 | 유전자 가위 넉-인을 이용하여 제조한 키메릭 항원 수용체 세포 및 이의 용도 |
| IL320156A (en) * | 2022-10-10 | 2025-06-01 | Kite Pharma Inc | New large scale car-t immune cell manufacturing method utilizing lentiviral vector transfection |
| CN116168765B (zh) * | 2023-04-25 | 2023-08-18 | 山东大学 | 基于改进strobemer的基因序列生成方法及系统 |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025006799A1 (en) * | 2023-06-27 | 2025-01-02 | Capstan Therapeutics, Inc. | Extracorporeal and ex vivo engineering of select cell populations from peripheral blood |
| CN116769722B (zh) * | 2023-07-04 | 2024-07-16 | 杭州荣谷生物科技有限公司 | 功能增强型car-nk细胞、其制备方法及其在免疫疗法中的应用 |
| CN121889169A (zh) * | 2023-09-25 | 2026-04-17 | 南京传奇生物科技有限公司 | 经修饰的免疫细胞和钙调磷酸酶抑制剂及其用途 |
| WO2025169136A1 (en) * | 2024-02-09 | 2025-08-14 | Takeda Pharmaceutical Company Limited | Dosing regimen for cd19 car nk cells in treating cancer |
| US20250333700A1 (en) * | 2024-02-28 | 2025-10-30 | Gene Solutions Joint Stock Company | Modified k562 feeder cell line expressing factors that enhance the activation and proliferation of natural killer cells and a method for its production |
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| HK1245080A1 (zh) * | 2014-10-27 | 2018-08-24 | University Of Central Florida Research Foundation, Inc. | 自然杀伤细胞的方法和组合物 |
| EP3138905A1 (en) * | 2015-09-04 | 2017-03-08 | Miltenyi Biotec GmbH | Method for natural killer cell expansion |
| CN107868791B (zh) * | 2016-09-26 | 2021-11-23 | 阿思科力(苏州)生物科技有限公司 | 一种加强型Slit2 CAR-T和CAR-NK细胞制备方法和应用 |
| EP3612210A4 (en) * | 2017-04-19 | 2021-01-27 | Board Of Regents, The University Of Texas System | MANIPULATED ANTIGEN RECEPTORS EXPRESSING IMMUNE CELLS |
| EP3755347B1 (en) * | 2018-02-21 | 2025-06-25 | Board of Regents, The University of Texas System | Universal antigen presenting cells and uses thereof |
| KR20210005240A (ko) * | 2018-05-03 | 2021-01-13 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 면역 관문 차단과 함께 키메라 항원 수용체를 발현하도록 가공된 천연 킬러 세포 |
| EP3790958A1 (en) * | 2018-05-08 | 2021-03-17 | Life Technologies Corporation | Compositions and methods for culturing and expanding cells |
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